东坡叙云∶昔尝观《千金方》三建散于病无所不治，而孙思邈着论，以谓此
方用药，节度不近人情，至于救急，其验特异。乃知神物效灵，不拘常制，至理关感，智不
能知。今予所得圣散子，殆此类也。自古论病，唯伤寒至为危急，表里虚实，日数证候，应
汗应下之法，差之毫厘，辄至不救。而用圣散子者，一切不问，阴阳二感，男女相易，状至
危笃者，连饮数剂，则汗出气通，饮食渐进，神宇完复，更不用诸药，连服取瘥。其余轻者
，额微汗，正尔无恙。药性小热，而阳毒发狂之类，入口即觉清凉，此殆不可以常理诘也。
时疫流行，平旦辄煮一釜，不问老少良贱，各饮一大盏，则时气不入其门。平居无病，能空
腹一服，则饮食快美，百疾不生，真济世卫生之宝也。其方不知所从来，故巢君数世宝之，
以治此疾，百不失一。余既得之，谪居黄州，连岁大疫，所全活者，至不可数。巢君初甚惜
此方，指江水为盟，约不传人。余切隘之，乃以传蕲水庞君安常。庞以医闻于世，又善着书
，故授之。且使巢君之名，与此方同不朽也。用药于后。
草豆蔻（十个） 木猪苓(去皮) 石菖蒲 茯苓 高良姜(锉炒) 独活 柴胡 吴茱萸 附
子(炮去皮脐) 麻黄(去节) 浓朴(姜汁制炒) 本 芍药 枳壳(麸炒去瓤) 白术 苍术
(泔浸) 半夏(汤洗去滑) 泽泻（各半两） 藿香 防风 细辛（各半两） 甘草(炙，一两)
上为锉散。每服五钱，水盏半，煎七分，去滓热服，空腹。此药以治寒疫，因东坡作序
，天下通行。辛未年，永嘉瘟疫，被害者不可胜数，往往顷时，寒疫流行，其药偶中，抑未
知方土有所偏宜，未可考也。东坡便谓与三建散同类，一切不问，似太不近人情。夫寒疫，
亦能自发狂。盖阴能发躁，阳能发厥，物极则反，理之常然，不可不知。今录以备疗寒疫，
用者宜审之，不可不究其寒温二疫也。辛巳年，余尝作《指治》，至癸巳复作此书，见《石
林避暑录》亦云∶宣和间，此药盛行于京师，太学生信之尤笃，杀人无数，医顿废之。然不
妨留以备寒疫，无使偏废也。
苏东坡叙述道：过去我曾观察《千金方》中的三建散，认为它对各种疾病都有疗效，而孙思邈撰写了论述，指出这个方子的用药剂量和法度不合常理，但在急救时，其效果却特别显著。由此可知，神妙的药物显现灵效，不拘泥于常规制度；深刻的医理关乎感应，智慧也无法完全知晓。如今我所得到的圣散子，大概就属于这一类。自古以来讨论疾病，只有伤寒最为危急，表里虚实、发病天数与证候表现，该发汗还是该攻下的治法，如果差错毫厘，就会导致无法挽救的后果。然而使用圣散子的人，一概不问这些区别，无论是阴感还是阳感，男女病情相互转化，症状极其危重的患者，连续服用几剂后，就能汗出气通，饮食逐渐恢复，精神神态完全复原，不再需要其他药物，连续服用即可痊愈。其余较轻的患者，额头微微出汗，便安然无恙。药性略微偏热，但对于阳毒发狂之类的病症，入口即感觉清凉，这大概不能用常理来责问。当时疫流行，清晨就煮好一锅药，不论老少贵贱，每人喝一大盏，那么时邪之气就不会侵入家门。平时没有生病，如果能空腹服用一次，就会觉得饮食甘美，百病不生，真是救世养生的宝物啊。这个方子不知道是从哪里来的，所以巢君几代人都珍视它，用它治疗这种疾病，百次尝试不失一次。我得到这个方子后，被贬谪居住在黄州，连年发生大瘟疫，所保全救活的人，多得数不过来。巢君起初非常吝惜这个方子，指着江水发誓，约定不传给他人。我恳切地劝说他，于是他将方子传给了蕲水的庞君安常。庞安常以医术闻名于世，又擅长著书立说，所以我接受了他的传承。并且希望让巢君的名字，与此方一同不朽。用药方法在后面。
草豆蔻（十个） 木猪苓（去皮） 石菖蒲 茯苓 高良姜（锉碎炒制） 独活 柴胡 吴茱萸 附子（炮制，去皮去脐） 麻黄（去节） 浓朴（姜汁制炒） 本（藁本） 芍药 枳壳（麸炒去瓤） 白术 苍术（淘米水浸泡） 半夏（热水洗去滑腻） 泽泻（各半两） 藿香 防风 细辛（各半两） 甘草（炙，一两）
以上药材切碎成散剂。每次服用五钱，用水一盏半，煎至七分，滤去药渣，趁热空腹服用。此药用于治疗寒疫，因为苏东坡作了序，所以在天下通行。辛未年，永嘉发生瘟疫，受害人数不胜数，往往在短时间内，寒疫流行，此药偶然有效，也不知道是否是方土有所偏宜，已不可考证了。苏东坡便说它与三建散同类，一概不问，似乎太不合常理。其实寒疫，也能导致发狂。因为阴盛能引发躁动，阳盛能引发厥逆，事物发展到极端就会向反面转化，这是正常的道理，不可不知。现在记录下来以备治疗寒疫之用，使用者应当审慎，不能不探究寒疫与温疫的区别。辛巳年，我曾经编写过《指治》，到癸巳年又编写了这本书，看到《石林避暑录》中也说：宣和年间，此药在京城盛行，太学生相信它尤为笃定，导致无数人死亡，医生们因此废弃了它。然而不妨保留它以备治疗寒疫，不要使其被片面地废弃。
Su Dongpo narrated: In the past, I observed Sanjian San (Three Jian Powder) from *Qianjin Fang* (Essential Prescriptions Worth a Thousand Gold), believing it to be effective for various diseases. However, Sun Simiao wrote an essay stating that the dosage and regulation of this prescription are contrary to human nature, yet in emergency rescue, its efficacy is exceptionally distinct. Thus, one knows that divine medicines manifest their spiritual efficacy without being bound by conventional systems; profound medical principles relate to resonance, which wisdom cannot fully comprehend. The Shengsanzi Formula (Holy Dispersion Formula) I obtained now is likely of this category. Since ancient times, when discussing diseases, only Shanghan (Cold Damage) has been extremely critical. Regarding exterior and interior, deficiency and excess, the number of days, and symptom manifestations, if the methods of sweating or purging are mistaken by even a hair's breadth, it leads to untreatable conditions. However, those who use Shengsanzi Formula do not inquire about these distinctions at all. Whether it is Yin or Yang infection, whether male or female conditions transform into each other, and even when symptoms are extremely critical, after drinking several doses continuously, sweat will emerge, Qi will flow freely, diet will gradually improve, and the spirit and demeanor will completely recover. No other medicines are needed; continuous administration leads to recovery. For milder cases, slight sweating on the forehead suffices, leaving the patient perfectly healthy. The medicinal properties are slightly warm, yet for conditions like Yang Du (Yang Toxin) causing madness, one feels cool immediately upon ingestion. This cannot be questioned by ordinary reasoning. During the epidemic, one pot was boiled at dawn. Regardless of age or status, everyone drank a large cup, ensuring that seasonal pathogens did not enter their homes. When healthy, taking one dose on an empty stomach makes food taste delicious and prevents all diseases. It is truly a treasure for saving the world and preserving health. The origin of this formula is unknown, so Lord Chao treasured it for generations, using it to treat this disease with a success rate of nearly one hundred percent. After obtaining it, I was demoted to Huangzhou, where major epidemics occurred for consecutive years. The number of people saved was incalculable. Lord Chao initially cherished this formula greatly, swearing by the river water that he would not pass it on. I earnestly persuaded him, and thus he passed it to Pang Anchang of Qishui. Pang was famous for his medical skills and good at writing books, so I accepted the transmission. And may Lord Chao's name remain immortal along with this formula. The ingredients follow below.
Caodoukou (Grass Cardamom Seed, Ten pieces) Zhu Ling (Polyporus Umbellatus, peeled) Shichangpu (Acori Tatarinowii Rhizoma) Fuling (Poria) Gaoliangjiang (Galangal Rhizome, chopped and stir-fried) Duhuo (Angelicae Pubescentis Radix) Chaihu (Bupleuri Radix) Wuzhuyu (Evodiae Fructus) Fuzi (Prepared Aconite Lateralis Radix, processed, peeled, and navel removed) Mahuang (Ephedrae Herba, nodes removed) Houpo (Magnoliae Officinalis Cortex, prepared with ginger juice and stir-fried) Bencao (Ligustici Rhizoma et Radix - Note: Text says "Ben", likely referring to Ligusticum or similar aromatic herb) Shaoyao (Paeoniae Radix) Zhike (Aurantii Fructus Immaturus, bran-fried and pith removed) Baizhu (Atractylodis Macrocephalae Rhizoma) Cangzhu (Atractylodis Rhizoma, soaked in rice water) Banxia (Pinelliae Rhizoma, washed with hot water to remove slipperiness) Zexie (Alismatis Rhizoma) [Each half liang] Huoxiang (Agastaches Herba) Fangfeng (Saposhnikoviae Radix) Xixin (Asari Radix et Rhizoma) [Each half liang] Gancao (Licorice Root, honey-fried, one liang)
Crush the above into a coarse powder. Take five qian per dose, add one and a half cups of water, decoct until seven-tenths remain, strain, and take hot on an empty stomach. This medicine treats Cold Epidemic. Because Su Dongpo wrote the preface, it became widely circulated throughout the realm. In the Xinwei year, a plague broke out in Yongjia, claiming countless lives. Often, within a short time, a cold epidemic spread, and this medicine happened to be effective. It is unknown whether this was due to local suitability, which cannot be verified. Su Dongpo claimed it was similar to Sanjian San and should be used indiscriminately, which seems too unreasonable. Actually, Cold Epidemic can also cause madness. Yin excess can lead to restlessness, and Yang excess can lead to Jue (cold extremities/reversal). When things reach an extreme, they reverse, which is a normal principle that must be understood. Now recorded for reference in treating Cold Epidemic, users should exercise caution and must investigate the differences between Cold and Warm Epidemics. In the Xinsi year, I compiled *Zhi Zhi*. By the Guisi year, I compiled this book. *Shilin Bushu Lu* (Record of Summer Retreat in Stone Forest) also states: During the Xuanhe era, this medicine was prevalent in the capital. University students believed in it fervently, resulting in countless deaths, leading doctors to abandon it. Nevertheless, it is advisable to retain it for Cold Epidemic to avoid one-sided abandonment.