伤寒脉微而厥,至七八日肤冷,其人躁,无暂安时者,此为藏厥,非蛔厥也。蛔厥者,其人当吐蛔。今病者
静而复时烦,此非藏寒。蛔上入膈故烦,须臾复止,得食而呕。又烦者,蛔闻食臭出,其人故吐蛔。吐蛔者,乌
梅丸主之,又主久利。
伤寒脉微厥冷烦躁者,在六七日,急灸厥阴以救之。此至七八日而肤冷,不烦而躁,是纯阴无阳,因藏寒而厥,
不治之证矣。然蛔厥之证,亦有脉微肤冷者,是内热而外寒,勿遽认为藏厥而不治也。其显证在吐蛔,而细辨在烦
躁。藏寒则躁而不烦,内热则烦而不躁。其人静而时烦,与躁而无暂安者迥殊矣。此与气上撞心,心中疼热,饥
不能食,食即吐蛔者,互文以见意也夫蛔者,虫也,因所食生冷之物,
与胃中湿热之气,相结而成。今风木为患,相火上攻,故不下行谷道而上出咽喉,故用药亦寒热相须也。此是胸
中烦而吐蛔,不是胃中寒而吐蛔,故可用连、柏。要知连、柏是寒因热用,不特苦以安蛔。看厥阴诸证,与本方相
符,下之利不止,与又主久利句合,则乌梅丸为厥阴主方,非只为蛔厥之剂矣。
乌梅丸∶
乌梅(二百枚) 细辛(六两) 干姜(十两) 黄连(十六两) 当归(四两) 附子(六两,炮去皮)
蜀椒(四两,出汗) 桂枝(六两,去皮) 人参(六两) 黄柏(六两)
上十味,异捣筛,合治之。以苦酒渍乌梅一宿,去核,蒸之五升米下,饭熟,捣成泥,和药令相得,内臼
中,与蜜杵三千下,丸如梧桐子大。先食饮服十丸,日三服,稍加至二十丸。禁生冷滑物臭食等。
蛔从风化,得酸则静,得辛则伏,得苦则下。故用乌梅、苦酒至酸者为君,姜,椒、辛、附、连、柏,大
辛大苦者为臣,佐参、归以调气血,桂枝以散风邪。藉米之气以和胃,蜜之味以引蛔,少与之而渐加之,则烦渐
止而蛔渐化矣。食生冷则蛔动,得滑物则蛔上入膈,故禁之。
伤寒病出现脉象微弱且四肢厥冷,到了七八天皮肤也发凉,病人躁动不安,没有片刻安宁的时候,这是脏厥,不是蛔厥。蛔厥的病人,应当有吐蛔虫的表现。现在的病人安静时多,只是偶尔心烦,这说明不是内脏虚寒。因为蛔虫上行进入膈部所以心烦,过了一会儿又停止,进食后会出现呕吐,再次心烦,是因为蛔虫闻到食物的气味而出动,所以病人会吐出蛔虫。吐出蛔虫的,用乌梅丸主治,乌梅丸同时也主治长期的腹泻。
伤寒病出现脉微、四肢厥冷、烦躁的症状,在发病六七天时,应当紧急艾灸厥阴经穴位来救治。如果到了七八天皮肤发冷,不烦而只躁动,这是纯阴无阳,因内脏虚寒导致的厥逆,属于不治之症。然而蛔厥证候,也有脉微、皮肤发冷的情况,这是内热外寒,不要立刻认定为脏厥而不治。其明显症状在于吐蛔,细微辨别在于烦躁与躁动的区别。内脏虚寒则表现为躁动而不心烦,内热则表现为心烦而不躁动。病人安静而偶尔心烦,与躁动而没有片刻安宁的情况截然不同。这与气上冲心脏、心中疼痛灼热、饥饿却不想吃东西、吃东西就吐蛔虫的症状,是互文见义的关系。蛔虫这种寄生虫,是因为食用生冷食物,与胃中的湿热之气相结合而形成的。现在风木之气为患,相火上攻,所以蛔虫不下行从肛门排出,反而上行从咽喉吐出,因此用药也需要寒热并用。这是胸中烦闷而吐蛔,不是胃中寒盛而吐蛔,所以可以使用黄连、黄柏。要知道黄连、黄柏是寒药热用,不仅是用苦味来安蛔。观察厥阴病的各种证候,与本方相符,误用下法导致腹泻不止,与“又主久利”这句话相合,那么乌梅丸就是厥阴病的主方,不仅仅是治疗蛔厥的药剂了。
乌梅丸方剂组成:
乌梅(二百枚) 细辛(六两) 干姜(十两) 黄连(十六两) 当归(四两) 附子(六两,炮制去皮)
蜀椒(四两,炒至出汗) 桂枝(六两,去皮) 人参(六两) 黄柏(六两)
以上十味药,分别捣碎过筛,混合处理。用醋浸泡乌梅一夜,去掉核,放在五升米下面蒸,饭熟后,将乌梅捣成泥状,与药物混合均匀,放入臼中,加蜂蜜捣击三千下,制成梧桐子大小的丸药。饭前饮服十丸,每天三次,逐渐增加到二十丸。禁止食用生冷、滑腻、臭秽的食物等。
蛔虫随风气而动,遇到酸味就安静,遇到辛味就潜伏,遇到苦味就下行。所以用乌梅、醋这样极酸的药作为君药,干姜、蜀椒、细辛、附子、黄连、黄柏这些大辛大苦的药作为臣药,佐以人参、当归来调和气血,桂枝来疏散风邪。借助米的气来和胃,蜜的味道来引导蛔虫,少量给予并逐渐增加剂量,那么心烦就会逐渐停止,蛔虫也会逐渐化解。吃生冷食物会使蛔虫扰动,吃滑腻食物会使蛔虫上行进入膈部,所以要禁止食用。
Taiyang disease presenting with a faint pulse and cold extremities, progressing to cold skin after seven or eight days, where the patient is restless without any moment of peace, is termed Zang Jue (Visceral Cold Reversal), not Hui Jue (Roundworm Reversal). Patients with Hui Jue typically vomit roundworms. The current patient is mostly quiet but occasionally irritable, indicating this is not due to visceral cold. The irritability arises because the roundworms move upward into the diaphragm; they stop after a short while. Vomiting occurs after eating, and subsequent irritability happens because the roundworms are stirred by the smell of food, causing the patient to vomit them. For patients vomiting roundworms, Wumei Wan (Mume Pill) is the primary formula; it also treats chronic diarrhea.
In Taiyang disease, if a patient presents with a faint pulse, cold extremities, and irritability within six or seven days, moxibustion on the Jueyin meridian should be urgently applied to rescue the condition. However, if after seven or eight days the skin becomes cold and the patient is restless without irritability, this indicates pure Yin without Yang, a reversal caused by visceral cold, which is an untreatable condition. Nevertheless, Hui Jue can also present with a faint pulse and cold skin; this represents internal heat with external cold. One should not hastily diagnose it as Zang Jue and deem it untreatable. The obvious sign is vomiting roundworms, while the subtle distinction lies in differentiating between irritability (fan) and restlessness (zao). Visceral cold manifests as restlessness without irritability, whereas internal heat manifests as irritability without restlessness. A patient who is quiet but occasionally irritable is distinctly different from one who is constantly restless without peace. This corresponds mutually with symptoms such as Qi rushing up to the heart, pain and heat in the epigastrium, hunger without desire to eat, and vomiting roundworms upon eating. Roundworms are parasites formed by the combination of consumed raw/cold foods and damp-heat qi in the stomach. Due to Wind-Liver pathogenic factors and Ministerial Fire attacking upward, the worms do not descend through the intestines but ascend to the throat. Therefore, treatment requires the simultaneous use of cold and hot herbs. This case involves chest irritability with vomiting roundworms, not gastric cold causing vomiting, so Huanglian (Coptis Rhizome) and Huangbai (Phellodendron Bark) can be used. It must be understood that Huanglian and Huangbai are cold herbs used in a hot context, not merely for their bitter taste to pacify roundworms. Observing various Jueyin syndromes matching this formula, and noting that purgation leads to unceasing diarrhea (aligning with "also treats chronic diarrhea"), Wumei Wan is the master formula for Jueyin diseases, not just a remedy for Hui Jue.
Wumei Wan:
Wumei (Fructus Mume, 200 pieces), Xixin (Asari Radix et Rhizoma, 6 liang), Ganjiang (Zingiberis Rhizoma Recens, 10 liang), Huanglian (Coptidis Rhizoma, 16 liang), Danggui (Angelicae Sinensis Radix, 4 liang), Fuzi (Aconiti Lateralis Radix Praeparata, 6 liang, processed and peeled), Shujiao (Sichuan Pepper Fruit, 4 liang, stir-fried until oil appears), Guizhi (Cinnamomi Ramulus, 6 liang, bark removed), Renshen (Ginseng Radix, 6 liang), Huangbai (Phellodendri Cortex, 6 liang).
The above ten ingredients are separately pounded and sifted, then mixed. Soak Wumei in vinegar overnight, remove pits, and steam over five sheng of rice. Once the rice is cooked, pound the Wumei into a paste, mix thoroughly with the other medicines, place in a mortar, add honey, and pound three thousand times to form pills the size of tung tree seeds. Take ten pills before meals with warm water, three times daily, gradually increasing to twenty pills. Avoid raw/cold, slippery, and foul-smelling foods.
Roundworms move with wind; they become quiet with sour flavors, dormant with pungent flavors, and descend with bitter flavors. Thus, Wumei and vinegar, being extremely sour, serve as the Sovereign herb. Ganjiang, Shujiao, Xixin, Fuzi, Huanglian, and Huangbai, being strongly pungent and bitter, serve as Ministers. Renshen and Danggui assist in regulating Qi and Blood, while Guizhi disperses Wind pathogens. The Qi of rice harmonizes the Stomach, and the flavor of honey guides the roundworms. Administering small amounts and gradually increasing them will gradually cease irritability and dissolve the roundworms. Consuming raw/cold food agitates the roundworms, and consuming slippery food causes them to ascend to the diaphragm; hence, these are prohibited.