好豉（一升绵裹） 葱白（一升切） 童尿（三升）
上三味。先熬豉葱。令相得。则投童尿。煮取二升。分再服。徐徐服之。覆令汗神验。
琥按上主治云。疫气伤寒。则知此疫气。非大瘟大疫。即四时反凉反热之气。人不及备。而病者率多相似。以故云。
疫。乃四时伤寒也。葱豉辛凉。以散肠胃之郁。童尿针寒。以降阳明之热。热郁去。而病自解矣。
栀子仁 黄连 黄柏 大黄（各半两） 好豉（一升） 葱白（七茎）
上 咀。以水八升。煮上四物六七沸。内葱豉。煮三升。顿服一升。日三。服汤讫。温覆令汗出不得汗者。复服重
发。此药无忌。特宜老小神良。
琥按上方。乃治阳明经府齐热。又疗三焦实热之剂。头痛壮热。四肢烦疼。经中热也。不能饮食。府中实也。解
除实热。此汤最神。
又治夏月伤寒四肢烦疼。发热。其人喜烦呕逆支满。剧如祸祟。寒热相搏。故令喜烦。宜七物黄连汤方。
黄连 茯苓 黄芩（各十八铢） 芍药 葛根（各一两） 甘草（一两六铢） 小麦（三合）
上 咀。以水七升。煮取三升。分三服。不能一升者。可稍稍服。之汤势安乃卧药主毒瓦斯。服汤之后。胸中热。及
咽喉痛。皆瘥。其明日。复煮一剂。如法服之。此汤无毒但除热。下气安病患。小儿服者。取三分之一。以水四升。煮
得二升。稍稍服。
琥按上方。乃清解阳明风热之剂。其用小麦者。犹仲景白虎汤中加粳米也。
又治时气病。烦热如火。狂言欲走宜水导散方。
【孙真人治疗疫气伤寒，发病三日以前未解的方子】
好豉（一升，用绵布包裹） 葱白（一升，切碎） 童尿（三升）
以上三味药。先煎煮豉和葱。待二者药性融合后，再投入童尿。煮取药液二升。分两次服用。慢慢服用。盖被令其出汗，效果神奇显著。
琥按：上述主治说明中提到“疫气伤寒”，由此可知这种“疫气”，并非大规模的瘟疫，而是指四季中反常的凉热之气。人们来不及防备，而患病者症状大多相似，因此称之为“疫”。这实际上是四时发生的伤寒病。葱和豉气味辛凉，用以疏散肠胃中的郁结；童尿性质寒凉，用以降泄阳明经的热邪。热邪郁结去除，疾病自然解除。
【又治伤寒四五日，头痛、高热、四肢烦痛、不能饮食的方子 / 七物黄连汤方】
栀子仁 黄连 黄柏 大黄（各半两） 好豉（一升） 葱白（七茎）
以上药物捣碎。用水八升，先煮前四味药，煮沸六七次后，加入葱和豉。继续煮至药液剩三升。一次性服下一升，每日三次。服药完毕后，温覆身体令其出汗。若不出汗，再次服用以发汗。此药没有禁忌，特别适合老人和儿童，疗效极佳。
琥按：上方是治疗阳明经和腑同时有热的方剂，也是治疗三焦实热的药剂。头痛、高热、四肢烦痛，是经中热邪所致；不能饮食，是腑中实邪所致。解除实热，此汤最为神效。
又用于治疗夏季伤寒，出现四肢烦痛、发热，患者喜欢烦躁、呕吐逆气、胸胁胀满。病情严重如同遭受鬼祟作怪，寒热邪气相互搏结，所以导致患者容易烦躁。宜用七物黄连汤方。
黄连 茯苓 黄芩（各十八铢） 芍药 葛根（各一两） 甘草（一两六铢） 小麦（三合）
以上药物捣碎。用水七升，煮取药液三升。分三次服用。如果一次喝不下一升，可以少量慢慢服用。服药后药势安定即可躺下休息。此药主要清除毒瓦斯。服药之后，胸中的热邪及咽喉疼痛，都会痊愈。第二天，再煮一剂，按照上述方法服用。此汤无毒，只起到清热、下气、安顿病患的作用。小儿服用时，取三分之一的剂量，用水四升，煮取二升，少量慢慢服用。
[Formula by Sun Simiao for treating epidemic qi cold damage, where the condition has not resolved within three days of onset]
Hao Chi (Fermented Soybean) (1 sheng, wrapped in silk gauze) Cong Bai (Scallion White) (1 sheng, chopped) Tong Niao (Child's Urine) (3 sheng)
Take the above three ingredients. First decoct the Hao Chi and Cong Bai until their properties are well combined. Then add the Tong Niao. Decoct to obtain 2 sheng of liquid. Divide into two doses. Administer slowly. Cover the patient to induce sweating; this is highly effective.
Hu notes: The aforementioned indications mention "epidemic qi cold damage." From this, we know that this "epidemic qi" does not refer to a large-scale plague, but rather to abnormal cool or hot air occurring out of season during the four seasons. People are unprepared for it, and those who fall ill tend to have similar symptoms; hence it is called "epidemic." This is essentially cold damage occurring in the four seasons. Cong Bai and Hao Chi are acrid and cool, used to disperse stagnation in the stomach and intestines. Tong Niao is cold in nature, used to descend heat from the Yangming channel. Once the heat and stagnation are removed, the disease resolves spontaneously.
[Another formula for treating cold damage after four or five days, characterized by headache, high fever, vexing pain in the four limbs, and inability to eat / Seven-Ingredient Coptis Decoction]
Zhi Zi Ren (Gardenia Seed) Huang Lian (Coptis Rhizome) Huang Bo (Phellodendron Bark) Da Huang (Rhubarb Root) (each 0.5 liang) Hao Chi (Fermented Soybean) (1 sheng) Cong Bai (Scallion White) (7 stalks)
Crush the above herbs. Use 8 sheng of water. Decoct the first four ingredients for six or seven boils. Add the Cong Bai and Hao Chi. Continue decocting until 3 sheng remains. Take 1 sheng at one time, three times a day. After taking the decoction, cover warmly to induce sweating. If sweating does not occur, administer again to promote diaphoresis. This medicine has no contraindications and is particularly excellent for both the elderly and children.
Hu notes: The above formula treats simultaneous heat in the Yangming channel and fu-organs. It is also a preparation for clearing excess heat from the Sanjiao (Triple Burner). Headache, high fever, and vexing pain in the four limbs indicate heat in the channel. Inability to eat indicates excess in the fu-organs. To resolve excess heat, this decoction is most efficacious.
It is also used to treat summer cold damage, presenting with vexing pain in the four limbs, fever, frequent irritability, vomiting and regurgitation, and chest/hypochondriac fullness. The condition may be severe as if possessed by evil spirits, with cold and heat pathogens battling each other, causing frequent irritability. The Seven-Ingredient Coptis Decoction is indicated.
Huang Lian (Coptis Rhizome) Fu Ling (Poria) Huang Qin (Scutellaria Root) (each 18 zhu) Shao Yao (Peony Root) Ge Gen (Kudzu Root) (each 1 liang) Gan Cao (Licorice Root) (1 liang 6 zhu) Xiao Mai (Wheat Grain) (3 he)
Crush the above herbs. Use 7 sheng of water. Decoct to obtain 3 sheng. Divide into three doses. If one cannot take 1 sheng at once, administer gradually. After the medicinal effect settles, lie down to rest. This medicine primarily clears toxic vapors. After taking the decoction, heat in the chest and sore throat will heal. On the following day, decoct another dose and administer according to the same method. This decoction is non-toxic; it only clears heat, directs qi downward, and calms the patient. For children, use one-third of the dose: use 4 sheng of water, decoct to 2 sheng, and administer gradually.
Hu notes: The above formula clears and resolves wind-heat in the Yangming channel. The use of Xiao Mai (Wheat Grain) is analogous to the addition of Jing Mi (Rice Grain) in Zhang Zhongjing's Bai Hu Tang (White Tiger Decoction).
It is also used to treat seasonal qi diseases, characterized by irritability and fever like fire, delirious speech, and restlessness wanting to run. The Water-Guiding Powder is indicated.