黄连（四两） 黄芩（一两） 芍药（二两） 鸡子黄（二枚） 阿胶（三两）
上五味。以水五升。先煮三物。取二升。去滓。内胶烊尽。小冷。内鸡子黄。扰令相得。温服七合。日三服。
成注云。阳有余。以苦除之。黄芩黄连之苦以除热。阴不足。以甘补之。鸡子黄阿胶之甘。以补血。酸。收也。
泄也。芍药之酸。收阴气而泄邪热。
琥按上方。乃治足少阴肾水不足。手少阴心火有余。火有余者。阳热内盛也。阳热盛。必以苦泄之。以寒胜之。故
用黄连为君。黄芩佐之。水不足者。阴血下虚也。阴血虚。必以甘温补之。酸平收之。故以阿胶鸡子黄为君。白芍药为
使也。且也。白芍药能敛阴益血。成注反云其泄邪热。殊非善解。
琥又按此方。凡系好色之徒。精血内虚而病邪热者。宜用之。或问好色之徒。复病风寒。此系阴证伤寒。须急投附
子四逆辈。犹恐未及。若用上药。是以寒治阴。不几速其死邪。余答云。人身一阴阳耳。而阴阳之根蒂。皆本于肾。好
色之徒。两肾受伤阴虚者多。阳虚者少。阳虚者。命门火衰也。阴虚者。肾中水竭也。凡人入房过度。则精多所遗。所
遗之精。皆为水而属阴。况其作强之时。心火先炽。火炽则水流。水愈流则火愈炽。五内燥热。外复伤寒而病邪热。两
热相夹。肾水必枯，其人发烦躁。而舌黑生芒。则就死矣。语云。伤寒偏打下虚人者。正此谓也。又今人有耽于淫乐。
精泄不止而死者。世俗不云走阴。而反云。走阳何谬之极邪。或又问云。诚如吾子所言。则是人病伤寒。无所谓阴证矣。
余答云。有之阴证者。中寒也。其病乃是阳虚阳虚之人。命门火衰。其平日必言语低微。饮食不化。四肢无力。腰以下
冷前阴不举。小便清白。此为真气不足。复为外寒所袭。表里四末皆冷。是为真阴之证。然亦不全因入房所致即小儿亦
有病阴证者。以胃中阳气虚。不能作郁热故也。其证详中寒论中。
少阴病得之一二日。口中和。其背恶寒者。当灸之附子汤主之。
附子汤方
少阴病身体痛。手足寒骨节痛。脉沉者。附子汤主之。
上二条证并汤方（俱见中寒论中）
少阴病。下利便脓血者。桃花汤主之。
桃花汤方
少阴病二三日至四五日腹痛。小便不利。下利不止。便脓血者。桃花汤主之。
上二条证。并汤方（俱见中寒论中）
少阴下利。便脓血者可刺。（此条即上条桃花汤证。愚意云可刺者。当是可灸之讹。正文与注并灸法俱见中寒论中）
少阴病吐利手足厥冷。烦躁欲死者。吴茱萸汤主之。（此条病亦真阴证。正文与注并汤俱见中寒论中）
少阴病下利。咽痛胸满心烦者。猪肤汤主之。（此条少阴病。亦自三阳经传来者。热邪传入少阴。少阴之经气虚。故
下利。其咽痛胸满心烦者。以其经之脉循喉咙。其支者从肺出。络心注胸中。尚论篇云。少阴邪热。充斥上下中间。无
所不到故也。成注云。与猪肤汤以调阴散热。）
黄连（四两） 黄芩（一两） 芍药（二两） 鸡子黄（两个） 阿胶（三两）
以上五味药。用水五升。先煎煮前三味药。取汁二升。滤去药渣。加入阿胶使其完全溶化。待药液稍凉后。加入鸡子黄。搅拌均匀使药液与蛋黄融合。每次温服七合。每日服用三次。
成无己注解说。阳气有余。用苦味药清除它。黄芩、黄连的苦味能清除热邪。阴气不足。用甘味药补益它。鸡子黄、阿胶的甘味能补血。酸味。具有收敛作用。
也有泄的作用。芍药的酸味。能收敛阴气并泄除邪热。
王琥按：上述方剂。是治疗足少阴肾水不足。手少阴心火有余的方子。心火有余。是阳热内盛。阳热盛。必须用苦味药泄热。用寒性药胜热。所以
用黄连作为君药。黄芩作为佐药。肾水不足。是阴血下虚。阴血虚。必须用甘温药补益。用酸平药收敛。所以以阿胶、鸡子黄为君药。白芍药为
使药。况且。白芍药能敛阴益血。成无己反而说它泄邪热。这绝不是好的解释。
王琥又按：此方。凡是喜好房事的人。精血内虚而患邪热病的。适宜使用。如果问喜好房事的人。又患了风寒。这是阴证伤寒。必须急投附
子四逆汤之类的药物。还恐怕来不及救治。如果使用上面的清热药。是用寒凉药治疗阴证。岂不是加速他的死亡吗？我回答说。人身不过是一阴阳罢了。而阴阳的根本。都源于肾。喜好房事的人。两肾受伤阴虚的多。阳虚的少。阳虚。是命门火衰。阴虚。是肾中水枯竭。凡人入房过度。则精气多所耗损。所
耗损的精。都是水而属于阴。何况在作强之时。心火先炽盛。火炽盛则水流。水愈流则火愈炽盛。五脏内部燥热。外部又受伤寒而患邪热病。两
种热邪夹杂。肾水必然枯涸。其人出现烦躁。舌黑生芒刺。就会死亡了。俗话说。伤寒偏容易打下虚之人。正是这个意思。又有如今有人沉溺于淫乐。
精气泄漏不止而死。世俗人不叫走阴。反而叫走阳。多么荒谬至极啊。有人又问我说。确实像您所说的那样。那么人患伤寒。就没有所谓的阴证了。
我回答说。有的。阴证。就是中寒证。这种病乃是阳虚。阳虚的人。命门火衰。他平日一定言语低微。饮食不消化。四肢无力。腰以下
冷。前阴不能勃起。小便清亮白色。这是真气不足。又被外寒侵袭。表里四肢末端都冷。这是真阴证。然而也不全是因为入房所致。即使是小儿也
有病阴证的。因为胃中阳气虚。不能产生郁热。所以如此。其症状详细记载在中寒论中。
少阴病得之一二日。口中平和。背部恶寒的。应当施灸。主用附子汤。
附子汤方
少阴病身体痛。手足寒冷骨节痛。脉沉的。主用附子汤。
以上两条证候及汤方（均见于中寒论中）
少阴病。下利便脓血的。主用桃花汤。
桃花汤方
少阴病二三日至四五日腹痛。小便不利。下利不止。便脓血的。主用桃花汤。
以上两条证候。及汤方（均见于中寒论中）
少阴下利。便脓血的可以针刺。（这一条即上一条桃花汤证。我认为“可刺”可能是“可灸”的讹误。正文与注解并灸法均见中寒论中）
少阴病吐利手足厥冷。烦躁欲死的。主用吴茱萸汤。（这一条病也是真阴证。正文与注解并汤方均见中寒论中）
少阴病下利。咽痛胸满心烦的。主用猪肤汤。（这一条少阴病。也是从三阳经传来的。热邪传入少阴。少阴的经气虚。所以
下利。其咽痛胸满心烦的。是因为它的经脉循行喉咙。其支脉从肺出。络心注入胸中。尚论篇说。少阴邪热。充斥上下中间。无
处不到。所以如此。成无己注解说。给予猪肤汤来调和阴气散热。）
Coptidis Rhizoma (4 liang), Scutellariae Radix (1 liang), Paeoniae Radix Alba (2 liang), Ovum Gallinae (2 pieces), Euphorbiae Semen Preparatum (3 liang) [Note: 'Ephedrae Herba' is incorrect for Ejiao; Ejiao is Donkey-hide Gelatin. Correcting to Asini Corii Colla].
Asini Corii Colla (Donkey-hide Gelatin).
The above five herbs. Use five sheng of water. First decoct the first three herbs. Obtain two sheng of liquid. Remove the dregs. Add the gelatin and melt it completely. When slightly cool, add the Ovum Gallinae (Chicken Egg Yolk). Stir until well mixed. Take seven he of warm medicine orally. Three times a day.
Cheng Wuji's commentary states: When Yang is in excess, eliminate it with bitter flavors. The bitterness of Huangqin (Scutellariae Radix) and Huanglian (Coptidis Rhizoma) eliminates heat. When Yin is deficient, tonify it with sweet flavors. The sweetness of Ji Zi Huang (Ovum Gallinae) and Ejiao (Asini Corii Colla) nourishes blood. Sour flavor has a consolidating effect.
It also has a draining effect. The sourness of Shaoyao (Paeoniae Radix) consolidates Yin Qi and drains pathogenic heat.
Wang Hu notes: The above formula treats insufficiency of Water of Foot-Shaoyin Kidney Meridian (Zu Shao Yin Shen Jing) and excess of Fire of Hand-Shaoyin Heart Meridian (Shou Shao Yin Xin Jing). Excess Heart Fire indicates internal flourishing of Yang-Heat. Flourishing Yang-Heat must be drained with bitter flavors and overcome with cold properties. Therefore, Huanglian (Coptidis Rhizoma) is used as the Sovereign herb, and Huangqin (Scutellariae Radix) as the Minister herb. Insufficiency of Kidney Water indicates deficiency of Yin-Blood below. Deficient Yin-Blood must be tonified with sweet-warm properties and consolidated with sour-flat properties. Therefore, Ejiao (Asini Corii Colla) and Ji Zi Huang (Ovum Gallinae) are used as Sovereign herbs, and Baishao Yao (Paeoniae Radix Alba) as the Envoy herb. Moreover, Baishao Yao can consolidate Yin and benefit blood. Cheng Wuji's comment that it drains pathogenic heat is certainly not a good interpretation.
Wang Hu further notes: This formula is suitable for those who indulge in sexual activities, suffering from internal deficiency of Essence-Blood and pathogenic heat diseases. If such individuals also contract Wind-Cold, this constitutes a Yin Syndrome Cold Damage (Yin Zheng Shang Han). One must urgently administer formulas like Fuzi Sini Tang (Aconite Decoction for Reversal of Cold), lest it be too late. Using the aforementioned cooling herbs to treat a Yin Syndrome with cold-natured drugs would merely accelerate death. I reply: The human body consists only of Yin and Yang. The root of Yin and Yang lies in the Kidney. Those who indulge in sex often suffer from Kidney Yin deficiency rather than Yang deficiency. Yang deficiency implies decline of Mingmen Fire (Gate of Life Fire). Yin deficiency implies exhaustion of Water in the Kidney. Excessive sexual activity leads to excessive loss of Essence. The lost Essence is Water and belongs to Yin. Furthermore, during sexual exertion, Heart Fire flares up first. Flaring Fire causes Water flow; more Water flow causes more Flaring Fire. Internal organs become dry and hot. External contraction of Cold Damage combined with pathogenic heat creates a dual heat condition. Kidney Water must wither. The patient becomes irritable, the tongue turns black with prickles, and death ensues. As the saying goes, "Cold Damage tends to harm those with weak constitutions," which refers precisely to this. There are also those today who indulge in lust, leak Essence endlessly, and die. Secular people do not call this "leaking Yin" but rather "leaking Yang," how extremely absurd! Someone asks again: "If what you say is true, then there is no such thing as Yin Syndrome in Cold Damage?" I reply: There is. Yin Syndrome refers to Zhong Han (Strike by Cold). This disease is due to Yang deficiency. Individuals with Yang deficiency have declining Mingmen Fire. They typically speak softly, fail to digest food properly, have weak limbs, feel cold below the waist, have impotence, and pass clear, white urine. This is deficiency of True Qi, compounded by external Cold invasion. Exterior, interior, and extremities are all cold. This is True Yin Syndrome. However, it is not solely caused by sexual activity. Even children can suffer from Yin Syndrome because of deficiency of Stomach Yang Qi, which fails to generate stagnant heat. Thus, the symptoms are detailed in the Treatise on Cold Strike.
In Shaoyin Disease, within one or two days, if the mouth feels normal and there is aversion to cold on the back, moxibustion should be applied. The primary formula is Fuzi Tang (Aconite Decoction).
Fuzi Tang Formula
In Shaoyin Disease, if there is body pain, cold hands and feet, bone and joint pain, and a deep pulse, the primary formula is Fuzi Tang (Aconite Decoction).
The above two syndromes and formulas (both found in the Treatise on Cold Strike)
In Shaoyin Disease, if there is diarrhea with pus and blood in the stool, the primary formula is Taohua Tang (Peach Kernel Decoction).
Taohua Tang Formula
In Shaoyin Disease, from two to three days up to four to five days, if there is abdominal pain, difficulty in urination, incessant diarrhea, and pus and blood in the stool, the primary formula is Taohua Tang (Peach Kernel Decoction).
The above two syndromes and formulas (both found in the Treatise on Cold Strike)
In Shaoyin diarrhea with pus and blood in the stool, acupuncture may be used. (This clause corresponds to the previous Taohua Tang syndrome. I believe "acupuncture may be used" is likely an error for "moxibustion may be used." The main text, commentary, and moxibustion methods are all found in the Treatise on Cold Strike.)
In Shaoyin Disease, if there is vomiting and diarrhea, cold extremities, and severe irritability bordering on despair, the primary formula is Wuzhuyu Tang (Evodia Decoction). (This syndrome is also a True Yin Syndrome. The main text, commentary, and formula are all found in the Treatise on Cold Strike.)
In Shaoyin Disease, if there is diarrhea, sore throat, chest fullness, and vexation, the primary formula is Zhufu Tang (Swine Skin Decoction). (This Shaoyin Syndrome is transmitted from the Three Yang meridians. Pathogenic Heat transmits into Shaoyin. The Qi of the Shaoyin meridian is deficient, hence diarrhea. The sore throat, chest fullness, and vexation occur because its meridian circulates along the throat, and its branch emerges from the Lung, connects with the Heart, and enters the Chest. Shanglun Pian states: "Shaoyin pathogenic heat fills the upper, lower, middle, and intermediate, reaching everywhere." Cheng Wuji comments: "Administer Zhufu Tang to harmonize Yin and dissipate heat.")