杨 疟状作止有时非若寒热往来或疏或数而作止无定时也凡感冒之人忽觉毛寒股栗筋节拘挛百骸鼓撼呕不欲食其
寒不可御未几复转而发热者此即温疟不必谓疟脉自弦或洪数或紧实或虚缓或刮涩皆为疟状但以外证别之用药固有本条
小柴胡汤如前斟酌加减亦是活法虽然血虚能生寒热败血亦作寒热阴阳相胜一证虽各有一方皆当以川芎为佐太阳病得之
八九日如疟状发热恶寒热多寒少其人不呕清便欲自可一日二三度发脉微缓者为欲愈也脉微而恶寒者此阴阳俱虚不可更
发汗更下更吐也面反有热色者未能解也以其不能得小汗出身必痒宜桂枝麻黄半各汤服桂枝汤大汗出脉洪大者与桂枝汤
如前法若形如疟日再发者汗出必解宜桂枝二麻黄一汤(成 经曰如服一剂病证犹在者故当复作本汤服之桂枝汤汗出后脉
洪大者病犹在也若形如疟日再发邪气客于荣卫之间也与桂枝二麻黄一汤以解散荣卫之邪)
桂枝二麻黄一汤方
枝桂(三钱去粗皮) 芍药(三钱) 麻黄(去节一钱六分) 生姜(切三钱) 甘草(一钱六分炙) 杏仁(去
皮尖四枚) 大枣(二枚擘)上七味以水二钟先煮麻黄一二沸去上沫纳诸药煮取一钟去渣分二服
病患头热汗出则解又如疟状日晡所发热者属阳明也脉实者宜下之脉虚浮者宜发汗下之与大承气汤发汗宜桂枝汤(虽
得阳明证未可便为里实审看脉候别内外有脉实者热已入腑为实可与大承气汤下之其脉浮虚者是热未入腑犹在于表也可
与桂枝汤发汗则愈)
妇人中风七八日续得寒热发作有时经水适断者此为热入血室其血必结故为疟状发作有时小柴胡汤主之(详妇人伤
寒)
杨氏指出:疟疾的症状发作和停止都有固定的时间,不像寒热往来(指恶寒与发热交替出现)那样或疏或密、发作和停止没有固定时间。凡是感冒的人,忽然觉得毛发寒冷、大腿战栗、筋骨关节拘挛紧缩、全身骨骼像被鼓撼动一样,恶心呕吐而不想进食,这种寒冷难以抵御,不久又转而发热的,这就是温疟(一种以高热为主、伴有寒战的疟疾)。不必认为只有脉象自弦才是疟疾,或者脉象洪数、紧实、虚缓、刮涩都是疟疾的表现,这些都是疟疾的症状,但应当通过外在证候来加以辨别。用药固然有本条所述的方法,如小柴胡汤(和解少阳的主方),可以根据前文的原则斟酌加减,这也是灵活运用的方法。虽然血虚能产生寒热,败血(瘀血阻滞)也会引起寒热,阴阳相互偏胜这一类病症,虽然各自有一方的主治,但都应当以川芎作为佐使药。
太阳病(外感风寒初期,邪在肌表)得之八九日,症状像疟疾一样,发热多而恶寒少,病人不呕吐,大小便基本正常,一天发作两三次,如果脉象微缓的,是病情将要痊愈的表现;如果脉象微而恶寒的,这是阴阳俱虚,不可再发汗、攻下或催吐;如果面部反而有热色的,说明病邪未能解除,因为不能得到微微的小汗,身体一定会发痒,适宜服用桂枝麻黄各半汤(调和营卫、小发其汗的方剂)。
服用桂枝汤后大汗出,脉象洪大的,仍给予桂枝汤,按照前面的方法处理。如果症状像疟疾,一天发作两次,汗出后必然解除,适宜服用桂枝二麻黄一汤(比桂枝麻黄各半汤发汗力更弱的方剂)。成无己说:如果服用一剂后,病证仍在,所以应当再次制作本汤服用。桂枝汤汗出后脉洪大,说明病邪仍在。如果症状像疟疾,一天发作两次,是邪气客居于荣卫之间,给予桂枝二麻黄一汤以解散荣卫之间的邪气。
桂枝二麻黄一汤方:
桂枝(三钱,去除粗皮)、芍药(三钱)、麻黄(去节,一钱六分)、生姜(切片,三钱)、甘草(炙,一钱六分)、杏仁(去皮尖,四枚)、大枣(两枚,掰开)。以上七味药,用水二钟,先煮麻黄一二沸,去掉上面的浮沫,加入其他药物,煮取一钟,去渣,分两次服用。
病患头部发热、汗出则病解。又如疟疾症状,在傍晚时分(日晡所,约下午3-5点)发热的,属于阳明病(邪入胃肠,燥热内结)。脉象实的,适宜用攻下法;脉象虚浮的,适宜用发汗法。攻下法给予大承气汤(峻下热结的主方),发汗法适宜用桂枝汤。虽然得到了阳明病的证候,但不可立即认为是里实证,需仔细审察脉候,辨别内外。如果脉象实,说明热邪已入腑成为实证,可以给予大承气汤攻下;如果脉象浮虚,说明热邪未入腑,仍然在表,可以给予桂枝汤发汗则痊愈。
妇女中风七八日后,持续出现寒热,发作有固定时间,月经恰好中断的,这是热入血室(热邪侵入子宫血海),血液必然凝结,所以出现像疟疾一样发作有时的症状,以小柴胡汤为主治方。(详细情况参见妇人伤寒章节)
Yang states: The onset and cessation of malaria symptoms occur at regular intervals, unlike the alternating chills and fever (alternating aversion to cold and fever) which may be sparse or frequent with no fixed timing for onset and cessation. In individuals who have contracted a common cold, if they suddenly feel cold hairs, trembling of the thighs, stiffness and spasm of muscles and joints, a sensation as if all bones are being shaken like a drum, nausea, vomiting, and loss of appetite, followed by an unbearable coldness that soon turns into fever, this is termed warm malaria (a type of malaria characterized by high fever accompanied by chills). One should not assume that only a wiry pulse indicates malaria; nor should one consider rapid and surging, tight and solid, deficient and slow, or rough and choppy pulses as definitive signs of malaria without differentiation. These are all manifestations of malaria, but they must be distinguished by external syndromes. Medication naturally follows specific guidelines, such as using Xiao Chai Hu Tang (Minor Bupleurum Decoction, the primary formula for harmonizing Shaoyang), which can be flexibly adjusted according to previous principles. Although blood deficiency can generate chills and fever, and stagnant blood (blood stasis obstruction) can also cause chills and fever, and although each syndrome of yin-yang imbalance has its own specific formula, Chuanxiong Rhizoma (Chuanxiong) should generally be used as an adjuvant herb in all cases.
In Taiyang disease (an early stage of exogenous cold-wind pathogen affecting the exterior), after eight or nine days, if the symptoms resemble malaria with more heat than cold, the patient does not vomit, bowel and bladder functions are relatively normal, and episodes occur two or three times a day, a slightly moderate pulse indicates impending recovery. If the pulse is faint with aversion to cold, this indicates deficiency of both yin and yang, and sweating, purgation, or emesis should not be induced. If the face appears flushed with heat, the pathogen has not been resolved because slight perspiration has not been achieved, leading to body itching; Guizhi Mahuang Ge Ban Tang (Cinnamon Twig and Ephedra Half-Dose Decoction) is appropriate to induce mild sweating.
After taking Guizhi Tang (Cinnamon Twig Decoction), if profuse sweating occurs and the pulse becomes surging, Guizhi Tang should still be administered according to the previous method. If symptoms resemble malaria occurring twice a day, resolution will follow sweating; Guizhi Er Mahuang Yi Tang (Cinnamon Twig Twice-Ephedra Once Decoction) is indicated. Cheng Wuji stated: If symptoms persist after one dose, the original decoction should be prepared again. A surging pulse after sweating from Guizhi Tang indicates the pathogen remains. If symptoms resemble malaria occurring twice daily, it signifies pathogenic factors lodged between Ying (Nutritive) and Wei (Defensive) levels; Guizhi Er Mahuang Yi Tang is used to dissipate these pathogens.
Formula for Guizhi Er Mahuang Yi Tang:
Guizhi (Cinnamomi Ramulus, 3 qian, remove coarse bark), Shaoyao (Paeoniae Radix Alba, 3 qian), Mahuang (Ephedrae Herba, 1.6 qian, remove nodes), Shengjiang (Zingiberis Rhizoma Recens, 3 qian, sliced), Gancao (Glycyrrhizae Radix et Rhizoma Praeparata cum Melle, 1.6 qian, honey-fried), Xingren (Armeniacae Semen Amarum, 4 pieces, remove skin and pointed ends), Dazao (Ziziphi Jujubae Fructus, 2 pieces, split). The above seven ingredients are boiled in two zhong of water. First, boil Mahuang for one or two boils, skim off the foam, then add the remaining herbs. Boil until one zhong remains, strain, and divide into two doses.
If the patient’s head feels hot and sweating occurs, the condition resolves. If symptoms resemble malaria with fever occurring in the late afternoon (Ribu, approximately 3-5 PM), this belongs to Yangming disease (excess heat in the stomach and intestines). If the pulse is excess, purgation is indicated; if the pulse is deficient and floating, sweating is indicated. For purgation, Da Chengqi Tang (Major Order the Qi Decoction) is used; for sweating, Guizhi Tang is appropriate. Although Yangming syndrome patterns are present, internal excess cannot be assumed immediately; pulse and condition must be carefully examined to distinguish interior from exterior. An excess pulse indicates heat has entered the fu organs becoming excess, allowing for purgation with Da Chengqi Tang. A floating-deficient pulse indicates heat has not entered the fu organs but remains on the exterior, allowing for resolution via sweating with Guizhi Tang.
In women suffering from wind-stroke for seven or eight days, if chills and fever continue to occur at regular intervals and menstruation happens to cease, this is termed "heat entering the blood chamber" (heat invading the uterus/blood sea). Blood coagulation results, causing malaria-like periodic symptoms. Xiao Chai Hu Tang (Minor Bupleurum Decoction) is the primary treatment. (For details, refer to the section on Cold Damage in Women.)