治真阴虚，相火炽而发热，其热在午后子前。（属阴分，）或皮寒骨蒸。（骨髓空虚，火
焰骨
唇红颧赤，口苦舌干，（皆内热之征也。）耳鸣目眩，腰膝酸软，四肢无力，倦怠嗜卧，（皆
精血虚损内伤之故。）大便燥结小便黄赤。（内热。）六脉弦数，或虚或无力。（皆虚损的症，
不必吐血咳嗽也。故有吐血咳嗽症，而无上文之内热虚症，脉数仍非虚劳，不可不辨。）若
病久饮食少思，大便溏泄，（脾胃伤之故也。）午后洒淅恶寒，少倾发热，或至鸡鸣，寅卯时
分盗汗出而解，并以此方，或六味、左归加减治之。
熟地（三钱至一二两） 生地（二三四钱，二地补肾阴，培其根本） 麦冬（三四五钱，清
肺降
山药（蒸用，三四五钱，同茯苓以补脾） 玉竹（五六钱，治虚损寒热，一切不足，用代参、
） 鳖甲（退劳热在骨及阴虚寒热往来之上品） 龟甲（补肾阴，退骨蒸。二甲酥炙，各三钱
至一两），加桂圆肉（十枚至三十枚），入人乳牛乳（各一杯），骨蒸内热，有汗加骨皮（二钱），
无汗加丹皮（一钱五分），腰痛加枸杞（三钱至八钱）、杜仲（二钱）、余用猪腰子（一枚）、猪
脊髓（五钱至八钱），五味（一分至一钱），怔忡不寐，加枣仁倍桂圆肉。咳嗽加桑白皮（蜜炙
，
血加藕汁一杯，或童便一杯。食少加苡仁（炒，五钱至一两）。泄泻去生地天冬乳汁，加白芍
（炒，三四钱）、大枣莲肉（二三十粒）、萸肉或用石斛煎汤煎药。肺经无热，肺脉按之无力者
，量加人参。
古方有人参固本丸，人参（二两）、二地二冬（各四两）是也。固本丸、加牛膝枸杞七味
均分，即集灵膏也。
此方君以甘寒滋阴添精之品，所谓损其肾者，益其精也。臣以二冬，保金而滋其生化
之源，恐太沉阴濡润，而又佐以甘平补脾之剂，顾其中气，备加减之法，以善其用。
治疗真阴亏损，相火亢盛而导致的发热，这种热象出现在午后至子时前。（属于阴分病变，）或者出现皮肤寒冷、骨中蒸热的症状。（骨髓空虚，虚火内扰，表现为嘴唇红、颧骨赤红，口苦舌干，（这些都是内热的征象。）耳鸣目眩，腰膝酸软，四肢无力，倦怠嗜卧，（这都是精血亏虚导致内伤的缘故。）大便干燥结滞，小便黄赤。（为内热所致。）六脉弦数，或虚或无力。（这些都是虚损的确切证候，不一定非要出现吐血咳嗽。所以，如果有吐血咳嗽的症状，但没有上述的内热虚症，且脉数，仍然不是虚劳病，这一点必须仔细辨别。）如果病程长久，饮食减少，思食欲望低，大便溏泄，（这是脾胃受损的缘故。）午后感到阵阵恶寒，片刻后发热，或者直到鸡鸣时分，寅卯时段盗汗出后热解，也使用此方，或者用六味地黄丸、左归丸加减来治疗。
熟地黄（三钱至一二两） 生地黄（二三四钱，二地补肾阴，培补根本） 麦冬（三四五钱，清肺降火） 山药（蒸制使用，三四五钱，同茯苓一起补脾） 玉竹（五六钱，治疗虚损引起的寒热，一切不足之症，可用它代替人参、黄芪） 鳖甲（退除骨中劳热及阴虚寒热往来的上品药） 龟甲（补肾阴，退除骨蒸。二甲酥炙，各三钱至一两），加桂圆肉（十枚至三十枚），加入人乳牛乳（各一杯），若骨蒸内热有汗，加地骨皮（二钱），无汗加牡丹皮（一钱五分），腰痛加枸杞子（三钱至八钱）、杜仲（二钱），其余用猪腰子（一枚）、猪脊髓（五钱至八钱），五味子（一分至一钱），怔忡不寐，加酸枣仁并倍用桂圆肉。咳嗽加桑白皮（蜜炙），吐血加藕汁一杯，或童便一杯。食欲少加薏苡仁（炒，五钱至一两）。泄泻去掉生地、天冬、乳汁，加白芍（炒，三四钱）、大枣莲肉（二三十粒）、山茱萸或用石斛煎汤煎药。肺经无热，肺脉按之无力者，酌情加人参。
古方有人参固本丸，由人参（二两）、二地二冬（各四两）组成。固本丸加上牛膝、枸杞七味均分，就是集灵膏。
此方以甘寒滋阴添精的药物为君药，所谓损伤肾精的，要益其精。臣药以二冬为主，保金（肺）而滋生化之源，担心药性过于沉阴濡润，又佐以甘平补脾的药物，顾护其中气，具备加减之法，以完善其功效。
Treats deficiency of True Yin (True Yin), with hyperactive Ministerial Fire (Ministerial Fire) causing fever, where the heat occurs from noon to midnight. (Belongs to the Yin aspect,) or presents with cold skin and steaming bone sensation. (Empty marrow, fire flames into bones; red lips and malar flush, bitter taste in mouth and dry tongue, (all are signs of internal heat.) tinnitus and vertigo, soreness and weakness of waist and knees, weakness in four limbs, fatigue and desire to lie down, (all due to injury of essence and blood deficiency.) dry and constipated stool, yellow and red urine. (Internal heat.) Six pulses are wiry and rapid, or empty or weak. (All are definite signs of deficiency and damage, not necessarily requiring hemoptysis or cough. Therefore, if there are symptoms of hemoptysis and cough but without the aforementioned internal heat and deficiency symptoms, and the pulse is rapid, it is still not consumption disease; this must be distinguished carefully.) If the disease has lasted long, with little appetite and desire for food, loose stools, (due to damage of Spleen and Stomach.) afternoon chills and shivering, followed by fever after a while, or until cockcrow time, sweating at night during Yin-Mao hours resolving the heat, also use this formula, or treat with Liuwei Dihuang Wan (Six-Ingredient Rehmannia Pill) or Zuogui Wan (Left Restoring Pill) with modifications.
Shu Di Huang (Prepared Rehmanniae Radix) (3 qian to 1-2 liang) Sheng Di Huang (Raw Rehmanniae Radix) (2-4 qian, these two Rehmannies tonify Kidney Yin and cultivate the root) Mai Dong (Ophiopogonis Radix) (3-5 qian, clears Lung and descends fire) Shan Yao (Dioscoreae Rhizoma) (steamed, 3-5 qian, together with Fu Ling tonifies Spleen) Yu Zhu (Polygonati Odorati Rhizoma) (5-6 qian, treats deficiency-damage with alternating cold and heat, all insufficiencies, used to replace Ren Shen and Huang Qi) Bie Jia (Testudinis Carapax et Plastrum) (superior herb for retreating bone-steaming labor-fever and alternating cold/heat in Yin deficiency) Gui Jia (Chelonis Carapax et Plastrum) (tonifies Kidney Yin, retreats bone-steaming. Both shells roasted with butter, each 3 qian to 1 liang), add Long Yan Rou (Longan Aril) (10 to 30 pieces), add Ren Ru (Human Milk) and Niu Ru (Bovine Milk) (each 1 cup). For bone-steaming internal heat with sweating, add Gu Pi (Cortex Lycii) (2 qian); without sweating, add Dan Pi (Moutan Cortex) (1.5 qian). For waist pain, add Gou Qi Zi (Lycii Fructus) (3-8 qian), Du Zhong (Eucommiae Cortex) (2 qian). Use remaining ingredients: Zhu Yao Zi (Porcine Kidney) (1 piece), Zhu Ji Sui (Porcine Spinal Cord) (5-8 qian), Wu Wei Zi (Schisandrae Fructus) (1 fen to 1 qian). For palpitations and insomnia, add Zao Ren (Ziziphi Spinosomi Semen) and double the amount of Long Yan Rou. For cough, add Sang Bai Pi (Mori Cortex) (honey-fried). For bleeding, add Ou Zhi (Nelumbinis Rhizomatis Jus) 1 cup, or Tong Bian (Child's Urine) 1 cup. For poor appetite, add Yi Yi Ren (Coicis Semen) (stir-fried, 5 qian to 1 liang). For diarrhea, remove Sheng Di, Tian Dong, and milks; add Bai Shao (Paeoniae Radix Alba) (stir-fried, 3-4 qian), Da Zao Lian Rou (Loti Semen cum Plumula) (20-30 grains), Yu Rou (Corni Fructus) or decoct Shi Hu (Dendrobii Caulis) to decoct the medicine. If Lung channel has no heat and Lung pulse is weak upon pressure, add Ren Shen (Ginseng Radix et Rhizoma) according to measure.
Ancient formulas include Ren Shen Gu Ben Wan (Ginseng Root-Solidifying Pill), composed of Ren Shen (2 liang), Er Di (two Rehmannies) and Er Dong (two Ophiopogons) (each 4 liang). Gu Ben Wan plus Niu Xi, Gou Qi, seven ingredients divided equally, is Ji Ling Gao (Ji Ling Elixir).
This formula uses sweet-cold herbs that nourish Yin and replenish essence as the Sovereign (Jun) drugs, meaning "for those who damage the Kidney, benefit their essence." The Ministers (Chen) are the two Dongs, protecting Metal (Lung) and nourishing the source of transformation and generation. Fearing they are too heavy, yin, and moistening, they are assisted by sweet-flat Spleen-tonifying agents to protect Middle Qi, with methods for modification to perfect its application.