夫病深而药浅，终见无功；病浅而药深，反增他剧。寒微而热药太过，内则目赤
咽痛，痰壅气促，外则斑烂痈毒，燥裂干红；热微而寒药太过，内则吐泻腹胀，外则
陷伏痒塌。势缓而投急剂，急则拂乱其经，病剧又宜劫药，缓则援生不及，以本药而治
本病，病去盒饭行别议。防变症而用变药，变症贵审乎将来，故偏行补法，未必尽为怯
弱，执用辛温，岂因概是虚寒？合用即用，当去即去，药随病迁，机要在我，故升麻进
于未点之先，若还泻甚而莫投；黄 用于催脓之际，必待气弱而可用。身无壮热，休加
干葛、柴胡，脸不繁红，勿进芩连、翘芥，拥遏只许疏通，投补剂则胸膨减食；内热便
宜清利，多发药则表烂疮疼。热壅心烦，丁桂须知患目；便溏胃弱，芩连误用夭亡。伤
食吐酸，先宜消导；不食干呕，须与和胃。粪焦热泻，温补岂其所宜；溏泻清稀，凉药
总为不合。胃虚弱而补阴，恐增泄泻；三焦拥而益阳，虑发狂颠，喘满便清，虽虚烦而
可补；气粗腹胀如秘结而可通。咳嗽有痰切勿乱投半夏；热冲作吐且教慢入干姜。气虚
不振，参 奏捷；脾胃虚寒，桂附成功。芩连，解热毒于未解；荆翘清血热于血泡。然
若势在行浆，此等皆为所叱。六七日内不起，保元勿禁；八九日外泻生，异攻何迟？
补法不宜早，加温药必须在后；发散乃是先锋，温补总为截阵。
疾病深重而用药轻浅，最终必然无效；疾病轻微而用药峻猛，反而会增加其他严重的症状。寒邪轻微却使用热药过量，在内则导致眼睛发红、咽喉疼痛、痰液壅盛、气息急促，在外则出现斑疹溃烂、痈疽毒疮、皮肤干燥皲裂且颜色干红；热邪轻微却使用寒药过量，在内则导致呕吐腹泻、腹部胀满，在外则出现痘疹内陷伏匿、瘙痒塌陷。病势缓和却投用急峻之剂，会扰乱经络气血；病情危重又适宜使用劫夺邪气之药，若用药过缓则救援生命不及。应当用本方治疗本病，病去之后便应另行商议对策。预防变证而使用针对变证的药物，变证贵在审察其未来的发展趋势，因此偏执于补法，未必是因为患者体质全部虚弱；固执地使用辛温药物，难道是因为所有情况都是虚寒吗？该合用时就合用，该去除时就去除，药物随着病情的变化而调整，关键在于医者对时机的把握。因此，升麻应在痘疹未出之前使用，但如果泻下严重则不可投用；黄芪用于催脓阶段，必须等到气虚时才可使用。身体没有高热，不要加入干葛（葛根）、柴胡；脸部不呈现繁复的红赤，不要进服黄芩、黄连、连翘、芥穗。痘疹拥遏不畅只允许疏通，投用补益剂则会导致胸部膨满、食欲减退；体内热邪适宜清利，如果过多发汗解表药物则会导致体表溃烂、疮疡疼痛。热邪壅滞导致心烦，需知丁香、肉桂可能引发眼部疾患；大便溏薄、胃气虚弱，误用黄芩、黄连可能导致死亡。伤食导致的吐酸，先宜消食导滞；不想进食且干呕，须调和胃气。粪便焦黑、热性腹泻，温补岂是适宜的；大便溏泄清稀，凉药总是不合适的。胃虚弱而补阴，恐怕增加泄泻；三焦壅塞而益阳，担心引发狂乱癫疾。气喘胸满但二便清长，虽然有心烦但属于可补之证；呼吸粗重、腹部胀满如同便秘那样需要通下。咳嗽有痰切勿乱投半夏；热气上冲导致呕吐，暂且缓慢加入干姜。气虚不振，人参奏效迅速；脾胃虚寒，肉桂、附子能获成功。黄芩、黄连，在未解的热毒中解除热毒；荆芥、连翘在血泡中清除血热。然而如果病势正处于行浆阶段，这些药物都会被斥责不用。六七日之内痘疹不起，保元汤不禁用；八九日之外痘疹生发迟缓，异功散为何迟疑？补法不宜过早，加用温药必须在后面；发散解表乃是先锋部队，温补固本总是作为截击阵地的后援。
When the disease is deep-seated but the medication is superficial, it ultimately yields no effect; when the disease is mild but the medication is profound, it may instead exacerbate other severe symptoms. If cold pathogenic factors are slight yet hot-natured medicines are overused, internally this leads to red eyes, sore throat, phlegm obstruction, and shortness of breath; externally, it results in ulcerated rashes, carbuncles, toxins, dry cracked skin, and a dry red appearance. If heat pathogenic factors are slight yet cold-natured medicines are overused, internally this causes vomiting, diarrhea, and abdominal distension; externally, it leads to involution, itching, and collapse of lesions. When the condition is slow-moving but urgent prescriptions are administered, urgency disrupts the meridians; when the condition is critical and "robbing" (strong purgative or resolving) medicines are indicated, using them too slowly fails to rescue life in time. One should use the fundamental prescription to treat the fundamental disease; once the disease is eliminated, further discussions on alternative strategies should follow. To prevent transformation syndromes by using medicines for transformed conditions, one must carefully anticipate future developments. Therefore, relying solely on tonification methods does not necessarily imply universal weakness; rigidly employing acrid-warm herbs does not imply that all cases are deficiency-cold. Combine when appropriate, discard when necessary; let the medicine adapt to the shifting disease, with the key lying in the practitioner's judgment. Thus, *Shengma* (Cimicifugae Rhizoma) should be advanced before eruption occurs, unless there is severe diarrhea, in which case it should not be administered; *Huangqi* (Astragali Radix) is used during the pus-formation stage, but only when Qi deficiency is present. If the body lacks high fever, do not add *Gegen* (Puerariae Lobatae Radix) or *Chaihu* (Bupleuri Radix); if the face is not excessively red, do not administer *Qinlian* (Scutellariae Baicalensis Radix et Coptidis Rhizoma), *Qiao* (Lonicerae Japonicae Flos), or *Jiejie* (Schizonepetae Spica). For obstruction and stagnation, only dredging and unblocking are permitted; administering tonics will cause chest fullness and reduced appetite. Internal heat is suitable for clearing and draining; excessive diaphoretic herbs lead to surface ulceration and sore sores. Heat obstruction causing irritability requires caution with *Dingxiang* (Caryophylli Flos) and *Guirou* (Cinnamomi Cortex), as they may affect the eyes; loose stools and weak stomach function mean that misusing *Qinlian* could be fatal. For food stagnation causing acid regurgitation, digestion-promoting and guiding-out methods are first indicated; for anorexia and dry retching, harmonizing the stomach is required. Scorched, hot diarrhea indicates that warming and tonifying are inappropriate; loose, clear, and thin diarrhea indicates that cooling medicines are altogether unsuitable. Tonifying Yin when the Stomach is weak may worsen diarrhea; benefiting Yang when the Sanjiao (Triple Burner) is obstructed may provoke mania or epilepsy. With wheezing, fullness, and clear urination/defecation, although there is irritability, tonification is permissible; with coarse breathing and abdominal distension resembling constipation, unblocking is appropriate. For cough with phlegm, avoid indiscriminate use of *Banxia* (Pinelliae Rhizoma); for vomiting caused by rising heat, introduce *Ganjiang* (Zingiberis Rhizoma) slowly. For Qi deficiency lacking vigor, *Renshen* (Ginseng Radix et Rhizoma) brings quick results; for Spleen-Stomach deficiency-cold, *Guizhi* (Cinnamomi Ramulus) and *Fuzi* (Aconiti Lateralis Radix Praeparata) achieve success. *Qinlian* clears heat toxins before they manifest; *Jingqiao* (Schizonepetae Spica et Lonicerae Japonicae Flos) clears blood heat from blood blisters. However, if the pathological trend is in the pustule-filling stage, such medicines are rejected. If within six to seven days the lesions do not rise, *Baoyuan Tang* (Preserve the Origin Decoction) is not prohibited; if after eight to nine days the generation is slow, why delay *Yigong San* (Extraordinary Merit Powder)? Tonification should not be applied too early; adding warming medicines must come later. Dispersing and releasing the exterior serves as the vanguard, while warming and tonifying serve as the rear guard.