大寒丑上，初之气，自大寒至春分，厥阴风木之位，一阳用事，其气
微。故曰少阳得甲子元头，常以大寒初交之气，分以六周甲子，以应六气
下。十二月、正月、二月少阳，三阴三阳亦同。
注云∶初之气为病，多发咳嗽，风痰，风厥，涎潮，痹塞口 ，半身不遂，失音，
风〔癫〕，风中妇人，胃中留饮，脐腹微痛，呕逆恶心，旋运惊悸，〔阳狂〕心风，
搐搦颤掉。初之〔气〕根据《内经》在上者宜吐，在下者宜下。
春分卯上，二之气，春分至小满，少阴君火之位，阳气〔动〕清明之
间，有阳明之位也。
注云∶二之气为病，多发风湿风热。经曰∶风伤于阳，湿伤于阴，微则头痛身
热，发作风湿之候，风伤于血也，湿伤于胃气也。是以风湿为病，阴阳俱虚，而脉
浮，汗出，身重，眠多鼻息，语言难出。以上二证，不宜热药，下之必死。二之气
病，宜以桂枝麻黄汤发汗而已。
小满以上，三之气，小满至大暑，少阳相火之位，阳〔气〕发万物俱
盛，故云太阳旺。其脉洪大而长，天气并万物人脉盛。
注云∶三之气为病，〔多发热〕，皆传足经者多矣，太阳、阳明、少阳、太阴、
厥阴、少阴。太阳者，发热恶寒，头项痛，腰背强。阳明者，肌痛目痛，鼻干不得
卧。少阳胸胁痛，耳聋，口苦，寒热往来而呕。此三阳属热。太阴者，腹满咽干，手足
自温，自利不渴，或腹满时痛。少阴，口燥舌干而渴。厥阴〔烦〕满，舌卷囊缩，
喘热闷乱，四肢厥冷，爪甲青色。三之气病，宜下清上凉〔及〕温养，不宜用巴豆
热药下之。
大暑未上，四之气，大暑至秋分，太阴湿土之位，阳气发散之后，阴已
用事，故曰太阴旺，此三阴三阳，与天气标本阴阳异矣。脉缓大而长，燥金
旺；紧细短涩，以万物干燥，明可见矣。
注云∶四之气为病，多发暑气，头痛身热，发渴，不宜作热病治（宜）以白虎汤，
得此病不传染，次发脾泄，胃泄，大肠泄，小肠泄，大瘕泄，霍乱吐泻，〔白利〕及
赤白相杂，米谷不消，肠鸣切痛，面浮足肿，目黄口干，胀满气痞，手足无力，小儿亦
如之。四之气〔病〕宜渗泄，五苓之类是也。
秋分酉上，五之气，秋分至小雪，阳明燥金之位，阳衰阴盛，故曰金气
旺，其脉细而微。
注云∶五之气为病，多发喘息，呕逆咳嗽，及妇人寒热往来， 疟瘅痔，消渴中
满，小儿斑疹痘疮。五之气病，宜以大柴胡汤解治表里。
小雪亥上，终之气，小雪至大寒，太阳寒水之位，阴极而尽，天气所
收，故曰厥阴旺。厥者，极也，其脉沉短而〔微〕。万物收藏在内，寒气闭
塞肤腠，气液不能越，故脉微也。
注云∶终之气为病，多发风寒，风痰湿痹，四肢不收。秋尽冬水复旺，水湿相搏，
肺气又衰，冬寒甚，故发则收引，病厥〔痿〕弱无以运用。水液澄澈清冷，大寒之疾，
积滞瘕块，寒疝血瘕。终之气病，宜破积发汗之药是也。
大寒节气之后进入丑月，为初之气阶段，时间跨度自大寒至春分，对应厥阴风木的主位。此时一阳之气开始发动，但气势尚微弱。因此说少阳得甲子元头之时，通常以大寒初交时的气候特征为准，将其分为六个六日周期（共三十六天），以对应六气的下行规律。十二月、正月、二月均涉及少阳之气，三阴三阳的演变规律与此相同。
注释指出：初之气引发的疾病，多表现为咳嗽、风痰、风厥、涎液上涌、痹症导致口眼歪斜或半身不遂、失音、风癫、妇女中风、胃中停饮、脐腹轻微疼痛、呕吐恶心、眩晕惊悸、阳狂心风、抽搐震颤等。对于初之气的病症，依据《内经》理论，病邪在上者宜用吐法，在下者宜用下法。
春分节气之后进入卯月，为二之气阶段，时间跨度从春分至小满，对应少阴君火的主位。此时阳气在清明之间活跃升发，同时也伴有阳明之位的影响。
注释指出：二之气引发的疾病，多发风湿和风热。经书说：“风邪伤及阳分，湿邪伤及阴分。”症状轻微时表现为头痛、身热，呈现风湿之候；若风邪伤血，湿邪伤胃气，则导致阴阳俱虚，脉象浮大，出汗，身体沉重，嗜睡，鼻息粗重，言语困难。以上两种证候，不宜使用热性药物，若误用攻下法必致死亡。二之气的病症，适宜用桂枝麻黄汤发汗治疗即可。
小满节气之后进入巳月，为三之气阶段，时间跨度从小满至大暑，对应少阳相火的主位。此时阳气发散，万物生长旺盛，所以说太阳之气旺盛。其脉象洪大而长，反映天气与人体经脉之气皆盛。
注释指出：三之气引发的疾病，多表现为发热，且多传变至足部经络，包括太阳、阳明、少阳、太阴、厥阴、少阴经。太阳经受病，表现为发热恶寒、头项强痛、腰背僵硬；阳明经受病，表现为肌肉疼痛、目痛、鼻干不得卧；少阳经受病，表现为胸胁疼痛、耳聋、口苦、寒热往来且呕吐。这三阳经的病证属于热证。太阴经受病，表现为腹部胀满、咽干、手足自温、自利而不渴，或腹部胀满有时疼痛；少阴经受病，表现为口燥舌干而渴；厥阴经受病，表现为烦闷、舌卷囊缩、喘促闷热烦躁、四肢厥冷、指甲青紫。三之气的病症，适宜采用下法、清上法、凉法及温养法，不宜使用巴豆等热性药物攻下。
大暑节气之前进入未月，为四之气阶段，时间跨度从大暑至秋分，对应太阴湿土的主位。此时阳气发散之后，阴气开始主事，所以说太阴之气旺盛。这里的三阴三阳，与天气标本阴阳有所不同。脉象缓大而长，反映燥金之气旺盛；若脉象紧细短涩，是因为万物干燥，显而易见。
注释指出：四之气引发的疾病，多表现为暑气致病，如头痛身热、口渴，不宜当作普通热病治疗，适宜用白虎汤。此类疾病不具传染性。其次可引发脾泄、胃泄、大肠泄、小肠泄、大瘕泄、霍乱吐泻、白痢及赤白相杂、米谷不消化、肠鸣剧痛、面浮足肿、目黄口干、胀满气痞、手足无力，小儿也会出现类似症状。四之气的病症，适宜用渗泄法，如五苓散之类的方剂。
秋分节气之后进入酉月，为五之气阶段，时间跨度从秋分至小雪，对应阳明燥金的主位。此时阳气衰退，阴气盛大，所以说金气旺盛，其脉象细而微。
注释指出：五之气引发的疾病，多表现为喘息、呕吐逆咳，以及妇女寒热往来、疟疾、疸病、痔疮、消渴、中满，小儿斑疹痘疮等。五之气的病症，适宜用大柴胡汤解表治里。
小雪节气之后进入亥月，为终之气阶段，时间跨度从小雪至大寒，对应太阳寒水的主位。此时阴极而尽，天气收敛，所以说厥阴之气旺盛。“厥”意为极，其脉象沉短而微。万物收藏于内，寒气闭塞肌肤腠理，气液不能外越，所以脉象微弱。
注释指出：终之气引发的疾病，多表现为风寒、风痰湿痹、四肢不收。秋末冬初水气复旺，水湿相互搏结，肺气又衰，冬季寒气甚重，所以发病时表现为收引，病证为厥逆、痿弱无力无法运用。水液清澈寒冷，为大寒之疾，积滞形成瘕块，寒疝血瘕。终之气的病症，适宜用破积发汗的药物进行治疗。
After the Great Cold solar term, entering the Chou month, marks the First Qi phase. This period spans from Great Cold to the Spring Equinox, corresponding to the position of Jueyin Wind-Wood. At this time, Yang Qi begins to function but remains weak. Thus, it is said that when Shaoyang receives the beginning of the Jiazi cycle, the climatic characteristics at the onset of Great Cold are typically used as a reference. This is divided into six cycles of sixty days (totaling 360 days) to correspond with the descent of the Six Qi. The twelfth, first, and second months all involve Shaoyang Qi, and the evolution of the Three Yin and Three Yang follows the same pattern.
The annotation states: Diseases caused by the First Qi often manifest as cough, wind-phlegm, wind-Jue, surging saliva, bi-syndrome leading to facial paralysis or hemiplegia, aphonia, wind-epilepsy, stroke in women, retained fluid in the stomach, mild pain in the umbilical and abdominal regions, vomiting and nausea, vertigo and palpitations, yang-manic heart-wind, convulsions, tremors, and shaking. Regarding diseases of the First Qi, according to the *Neijing* (Inner Canon), if the pathogen is above, emesis should be induced; if below, purgation should be applied.
After the Spring Equinox, entering the Mao month, marks the Second Qi phase. This period spans from the Spring Equinox to the Beginning of Summer, corresponding to the position of Shaoyin Sovereign Fire. At this time, Yang Qi becomes active and clear between the Qingming period, accompanied by the influence of the Yangming position.
The annotation states: Diseases caused by the Second Qi often involve wind-dampness and wind-heat. The classics state: "Wind pathogen injures the Yang aspect, dampness pathogen injures the Yin aspect." Mild symptoms include headache and fever, presenting as wind-dampness patterns; if wind injures the blood and dampness injures the Stomach Qi, it leads to deficiency of both Yin and Yang, floating pulse, sweating, heavy body, excessive sleepiness, coarse nasal breathing, and difficulty speaking. For these two types of syndromes, hot medicines are contraindicated; misapplication of purgation will lead to death. Diseases of the Second Qi are suitable for treatment with Guizhi Mahuang Tang (Cinnamon Twig and Ephedra Decoction) to induce sweating.
After the Beginning of Summer, entering the Si month, marks the Third Qi phase. This period spans from the Beginning of Summer to the Major Heat, corresponding to the position of Shaoyang Ministerial Fire. At this time, Yang Qi disperses, and all things grow vigorously, hence it is said that Taiyang Qi is prosperous. The pulse is large, surging, and long, reflecting that both heavenly climate and human meridians are abundant.
The annotation states: Diseases caused by the Third Qi often manifest as fever and frequently transmit to the foot meridians, including Taiyang, Yangming, Shaoyang, Taiyin, Jueyin, and Shaoyin. Taiyang meridian disease presents with fever, aversion to cold, pain and stiffness in the head and neck, and stiffness in the lower back and back. Yangming meridian disease presents with muscle pain, eye pain, dry nose, and inability to lie down. Shaoyang meridian disease presents with chest and hypochondriac pain, deafness, bitter taste in the mouth, alternating chills and fever, and vomiting. These three Yang meridians' diseases belong to heat syndromes. Taiyin meridian disease presents with abdominal fullness, dry throat, warmth of hands and feet, spontaneous diarrhea without thirst, or abdominal fullness with occasional pain. Shaoyin meridian disease presents with dry mouth and tongue with thirst. Jueyin meridian disease presents with irritability and fullness, curled tongue and retracted scrotum, panting, stifling heat, restlessness, cold limbs, and cyanotic fingernails. Diseases of the Third Qi are suitable for purgation, clearing the upper, cooling, and warming/nourishing methods, but should not use hot purgatives like Radix et Rhizoma Imperatoris (Badou).
Before the Major Heat solar term, entering the Wei month, marks the Fourth Qi phase. This period spans from Major Heat to the Autumn Equinox, corresponding to the position of Taiyin Damp-Earth. After Yang Qi disperses, Yin Qi begins to govern, hence it is said that Taiyin Qi is prosperous. The Three Yin and Three Yang here differ from the heaven-earth root-and-branch Yin-Yang. A slow, large, and long pulse indicates prosperity of Dry-Metal Qi; a tight, fine, short, and choppy pulse indicates dryness of all things, which is evident.
The annotation states: Diseases caused by the Fourth Qi often manifest as summer-heat illness, such as headache, fever, and thirst. They should not be treated as ordinary heat diseases but are suitable for Baihu Tang (White Tiger Decoction). Such diseases are non-contagious. Subsequently, they may cause Pi-xie (Spleen diarrhea), Wei-xie (Stomach diarrhea), Dachang-xie (Large Intestine diarrhea), Xiaochang-xie (Small Intestine diarrhea), Dajia-xie (Major mass diarrhea), cholera with vomiting and diarrhea, white dysentery, mixed red and white dysentery, undigested food, loud borborygmus and severe pain, facial and foot edema, yellow eyes, dry mouth, distension and qi stagnation, weakness of hands and feet, and similar symptoms in children. Diseases of the Fourth Qi are suitable for leaching and draining methods, such as Wuling San (Five Ling Powder).
After the Autumn Equinox, entering the You month, marks the Fifth Qi phase. This period spans from the Autumn Equinox to the Beginning of Snow, corresponding to the position of Yangming Dry-Metal. At this time, Yang declines and Yin prevails, hence it is said that Metal Qi is prosperous, and the pulse is fine and faint.
The annotation states: Diseases caused by the Fifth Qi often manifest as panting, vomiting, retching, and cough, as well as alternating chills and fever in women, malaria, jaundice, hemorrhoids, xiao-ke (wasting-thirst), middle-fullness, and infant rashes and smallpox. Diseases of the Fifth Qi are suitable for treatment with Da Chaihu Tang (Greater Bupleurum Decoction) to resolve both exterior and interior conditions.
After the Beginning of Snow, entering the Hai month, marks the Final Qi phase. This period spans from the Beginning of Snow to Great Cold, corresponding to the position of Taiyang Cold-Water. At this time, Yin reaches its extreme and ends, and Heaven's energy gathers, hence it is said that Jueyin Qi is prosperous. "Jue" means extreme. The pulse is deep, short, and faint. All things store within, cold Qi blocks the skin and pores, preventing Qi and fluids from escaping, hence the pulse is faint.
The annotation states: Diseases caused by the Final Qi often manifest as wind-cold, wind-phlegm, damp-bi, and flaccidity of the four limbs. At the end of autumn and beginning of winter, Water Qi revives and prospers. Water and dampness contend, Lung Qi declines, and winter cold is severe, so disease onset involves contraction, resulting in Jue-ni (reversal cold) and wei-ruo (flaccid weakness) with inability to move. Fluids are clear and cold, representing major cold diseases, accumulation and masses, cold hernia, and blood masses. Diseases of the Final Qi are suitable for herbs that break accumulations and induce sweating.