夏伤于暑，秋必病疟。（治法见疟门。）
〔《脉》〕阴阳俱盛，重于阴者，变为温疟。
春应暖反寒，夏应热反凉，秋应凉反热，冬应寒反温，此非其时而有其气，是以一岁之中，长幼之病多相
似者，为时行瘟疫病也。（论见伤寒。）
〔《活》〕一岁之中，病无长幼率相似，此则时行之气，俗谓之天行是也。老君神明散、务成子萤火丸、
圣散子败毒散，不拘日数浅深吐下，随症施行。所以圣散子不问阴阳表里也。
老君神明散 治瘟疫。
白术（一钱） 桔梗（一分） 细辛（一两） 附子（一两，炮去黑皮） 乌头（四两，炮去皮尖）
上五味，为粗末，缝绢袋盛带之，居闾里皆无病。若有疫疠者，温酒服方寸匕，覆取汗，得吐则瘥。若经
三四日，抄三寸匕，以水一碗，煮令大沸，分三服。
圣散子 苏内翰序，全文见《活人书》，时毒流行，用圣散子者，一切不问阴阳之感，连服取瘥，不可
与伤寒比也。若疾疫之行，平旦辄煮一釜，不问老幼良贱，各一大盏，实时气不入。
草豆蔻（十个，面裹，煨，去皮） 猪苓（去皮） 石菖蒲 茯苓 良姜 独活（去芦） 附子（炮制，
去皮脐） 麻黄（去根） 浓朴（去皮，姜制） 本 芍药 枳壳（炒，去穣） 柴胡 泽泻 细辛
防风（去芦） 白术 藿香 半夏 吴茱萸（汤洗） 苍术 甘草（各半两）
上 咀，每服五钱，水一盏半，煮取八分，去渣热服，余渣再煎，空心服之。
上二方治疫，虽不分阴阳，然亦寒多、表多者宜之。
〔丹〕众人病一般者，是谓天行时疫，有宜补宜散宜降方。
大黄 黄芩 黄连 人参 桔梗 防风 人中黄 滑石 香附 苍术
上曲糊为丸，每服五七十丸，分气、血、痰，作汤使送下。气虚者，四君子汤送下。血虚者，四物汤送下。
痰多者，二陈汤送下。热甚者，用童便和前药同送下。
〔《本》〕粪清，腊月截淡竹，去青皮，浸渗取汁。治天行、热狂、热疾、中毒，并恶疮、蕈毒。取汁浸
皂角、甘蔗，治天行热疾。
〔丹〕解一切灾病。用粉草五两，细切，微炒，量病患吃得多少酒，取无灰酒一处研，去渣温服。须臾大
泻，毒亦随出，虽十分渴，亦不可饮水，饮水难救。
上三方，热多、里多者宜之。
〔洁〕雄黄丸 治疫，不相染。
雄黄（一两，研） 赤小豆（炒熟） 丹参 鬼箭羽（各二两）
上为细末，炼蜜为丸，如桐子大。每日空心以温水下五丸，可与病同床共衣，亦不相染矣。
〔《活》〕务成子萤火丸 主辟疫疾，恶气，百鬼、虎、野狼、蛇、虺、蜂、虿诸毒，五兵白刃，盗贼凶害
皆辟之。
萤火 鬼箭羽（去皮） 蒺藜（各一两） 雄黄 雌黄（各二两） 矾石（一两，烧汁尽） 羚羊角 锻灶灰
铁锤柄（入锻处烧焦，用一分半）
上九味，捣为散，以鸡子黄，并雄鸡冠一具，和之如杏仁大。作三角缝囊，盛五丸，带左臂上，仍可挂于
户上。
春应暖而清气折之，则实邪在肝，升麻解肌汤主之。（方见温病。）夏应暑而寒气折之，则实邪在心，
调中汤、射干汤、半夏桂枝甘草汤选用之。
调中汤 治夏月初秋忽有暴寒折于盛热，结于四肢，则壮热头痛，寒伤于胃则下利，或血、或水、或赤，壮热
晕闷，脉数，宜下之。
大黄（去皮，三分） 黄芩 芍药 葛根 桔梗 茯苓（去皮） 本（择真者，无则川芎代之） 白术
甘草（炙。以上各半两）
上 咀，每服五钱，水一盏半，煮取一盏，移时再服之。得快利便止，小儿减与服。（虚冷，不壮热，但下利，
或霍乱者，不宜服此。）
射干汤（方见哑。） 半夏桂枝甘草汤（方见咽痛。）
秋应凉而反大热，抑之则实邪在肺，白虎加苍术汤、茵陈汁调五苓散。（白虎苍术汤见暑，五苓散见渴。）
〔丹〕冬温为病，非其时而有其气者，冬时严寒，君子当闭藏而反发泄于外，专用补药带表药。
作人中黄方
以竹筒两头留节，一节中作一窍，内甘草于中，仍以竹木钉塞其窍，置大粪缸内浸一月，取出晒干，用治
瘟毒。（用此药一味，入补药带表，同煎服之。）
〔《活》〕冬应寒而反大温，抑之则实邪在肾，宜葳蕤汤。（方见风湿。）
夏天感受暑邪，到了秋天必定发生疟疾。（治疗方法参见疟疾门类。）
《脉经》指出：如果阴阳脉象都盛大，其中阴气偏盛严重的，会转变为温疟。
春天本该温暖却反而寒冷，夏天本该炎热却反而凉爽，秋天本该凉爽却反而炎热，冬天本该寒冷却反而温暖，这种在非其时却有非其气的情况，导致一年之中，无论老少患病症状大多相似，这称为时行瘟疫病。（详细论述参见伤寒章节。）
《活人书》指出：一年之中，病人不分老少症状大多相似，这是时行之气，俗称天行。老君神明散、务成子萤火丸、圣散子败毒散，不拘泥于病程日数的深浅，根据病情采用催吐或泻下的方法，随症施治。所以圣散子不问是阴证还是阳证、表证还是里证。
老君神明散 治疗瘟疫。
白术（一钱） 桔梗（一分） 细辛（一两） 附子（一两，炮制后去掉黑皮） 乌头（四两，炮制后去掉皮和尖）
以上五味药，研成粗末，缝在绢袋中佩戴，居住在乡里间都不会生病。如果有疫疠之气侵袭，用温酒送服方寸匕的药量，覆盖身体取汗，如果呕吐出来则病愈。如果经过三四天，取三寸匕的药量，用水一碗，煮沸，分三次服用。
圣散子 苏内翰作序，全文见《活人书》，当时毒流行，使用圣散子的，一概不问是阴感还是阳感，连续服用直到病愈，不能与伤寒病相比。如果是疾疫流行，清晨就煮好一锅药，不分老少贵贱，每人一大盏，即时饮用，邪气就不会侵入。
草豆蔻（十个，用面包裹，煨熟，去皮） 猪苓（去皮） 石菖蒲 茯苓 良姜 独活（去芦头） 附子（炮制，去皮和脐） 麻黄（去根） 浓朴（去皮，姜汁制） 本（藁本） 芍药 枳壳（炒，去瓤） 柴胡 泽泻 细辛 防风（去芦头） 白术 藿香 半夏 吴茱萸（汤洗） 苍术 甘草（各半两）
以上药材切碎，每次服用五钱，水一盏半，煮取八分，去渣热服，剩下的药渣再煎，空腹服用。
以上两个方子治疗疫病，虽然不区分阴阳，但也是寒邪多、表邪多的情况适宜使用。
《丹溪心法》指出：众人得病症状一般相同，这叫天行时疫，有适宜补益、发散、降逆的方剂。
大黄 黄芩 黄连 人参 桔梗 防风 人中黄 滑石 香附 苍术
以上药物用曲糊制成丸药，每次服用五七十丸，根据气、血、痰的不同，分别用汤药送下。气虚者，用四君子汤送下。血虚者，用四物汤送下。痰多者，用二陈汤送下。热势重者，用童便和前药一同送下。
《本草纲目》指出：粪清，腊月截取淡竹，去掉青皮，浸泡渗滤取汁。治疗天行、热狂、热疾、中毒，以及恶疮、蕈毒。取汁浸泡皂角、甘蔗，治疗天行热疾。
《丹溪心法》指出：解除一切灾病。用粉草五两，细细切碎，微炒，根据病患能喝多少酒，取无灰酒一起研磨，去渣温服。不久后会大泻，毒素也随之排出，即使十分口渴，也不可饮水，饮水则难以救治。
以上三个方子，热邪多、里邪多的情况适宜使用。
《洁古针经》指出：雄黄丸 治疗疫病，不被传染。
雄黄（一两，研细） 赤小豆（炒熟） 丹参 鬼箭羽（各二两）
以上研成细末，炼蜜为丸，如梧桐子大。每天空腹用温水送服五丸，可以与病人同床共衣，也不会被传染。
《活人书》指出：务成子萤火丸 主要辟除疫疾、恶气，以及百鬼、虎、野狼、蛇、虺、蜂、虿等各种毒害，兵器白刃、盗贼凶害都能辟除。
萤火 鬼箭羽（去皮） 蒺藜（各一两） 雄黄 雌黄（各二两） 矾石（一两，烧至汁液流尽） 羚羊角 锻灶灰 铁锤柄（入锻处烧焦，取一分半）
以上九味药，捣碎成散剂，用鸡蛋黄和一只雄鸡冠调和，做成杏仁大小的丸药。制作三角缝囊，装入五丸，佩戴在左臂上，也可以挂在门上。
春天本该温暖却被清气折损，则实邪在肝，用升麻解肌汤主治。（方剂见温病章节。）夏天本该暑热却被寒气折损，则实邪在心，选用调中汤、射干汤、半夏桂枝甘草汤。
调中汤 治疗夏初秋初忽然有暴寒折伤盛热，结于四肢，则出现壮热头痛，寒邪伤胃则下利，或者便血、或者水样便、或者赤色便，壮热晕闷，脉数，适宜用下法。
大黄（去皮，三分） 黄芩 芍药 葛根 桔梗 茯苓（去皮） 本（选真品，没有则用川芎代替） 白术 甘草（炙。以上各半两）
以上切碎，每次服用五钱，水一盏半，煮取一盏，过一段时间再服。得到快利大便就停止，小儿减量服用。（虚冷，不壮热，只是下利，或者霍乱者，不宜服用此方。）
秋天本该凉爽却反而大热，抑制它则实邪在肺，用白虎加苍术汤、茵陈汁调五苓散。（白虎苍术汤见暑病章节，五苓散见渴病章节。）
《丹溪心法》指出：冬温为病，是非其时而有其气，冬天严寒，君子应当闭藏却反而发泄于外，专用补药配合解表药。
制作人中黄方
用竹筒两头保留节，在一节中间开一个孔，将甘草放入其中，仍用竹木钉塞住孔，放在大粪缸内浸泡一个月，取出晒干，用来治疗瘟毒。（只用这一味药，加入补药和解表药中，同煎服用。）
In summer, one is injured by summer-heat; in autumn, malaria must occur. (For treatment methods, see the Malaria section.)
[From *Mai Jing*] If both Yin and Yang pulses are full and vigorous, with Yin being more severe, it transforms into Warm Malaria.
If spring should be warm but turns cold, summer should be hot but turns cool, autumn should be cool but turns hot, and winter should be cold but turns warm, this is having the qi of a different season at the wrong time. Therefore, throughout the year, the illnesses of people of all ages tend to be similar, which is called an epidemic disease of the seasonal passage. (The discussion can be found in the Treatise on Cold Damage section.)
[From *Huo Ren Shu*] Throughout the year, if patients of all ages have similar symptoms, this is the qi of seasonal passage, commonly known as Tian Xing (Heavenly Transmission). Lao Jun Shen Ming San, Wuchengzi Yinghuo Wan, and Sheng San Zi Bai Du San can be used regardless of the duration or depth of the illness; emetics or purgatives are applied according to the symptoms. Thus, Sheng San Zi does not distinguish between Yin/Yang or Exterior/Interior patterns.
Lao Jun Shen Ming San treats Plague.
Bai Zhu (Atractylodis Rhizoma, 1 qian), Jie Geng (Platycodonis Radix, 1 fen), Xi Xin (Asari Radix et Rhizoma, 1 liang), Fu Zi (Aconiti Lateralis Radix Praeparata, 1 liang, processed to remove black skin), Wu Tou (Aconiti Radix, 4 liang, processed to remove skin and tip).
The above five herbs are ground into coarse powder, placed in a silk bag, and worn. Living among villages, one will remain free of disease. If plague qi invades, take one fang cun bi with warm wine, cover up to induce sweating; vomiting indicates recovery. If three or four days have passed, take three cun bi, boil in one bowl of water until boiling vigorously, and divide into three doses.
Sheng San Zi: Preface by Su Nei Han, full text in *Huo Ren Shu*. When toxic heat spreads, use Sheng San Zi without distinguishing between Yin or Yang infection; take continuously until cured. It cannot be compared to Cold Damage diseases. During epidemics, cook a pot at dawn; give one large cup to everyone regardless of age, status, or gender, so that seasonal qi does not enter.
Cao Dou Kou (Tsaoko Cardamomi Fructus, 10 pieces, wrapped in flour, baked, peel removed), Zhu Ling (Polypori Sclerotium, peel removed), Shi Chang Pu (Acori Tatarinowii Rhizoma), Fu Ling (Poria), Liang Jiang (Zingiberis Rhizoma Recens), Du Huo (Angelicae Pubescentis Radix, remove rhizome), Fu Zi (Aconiti Lateralis Radix Praeparata, processed, remove skin and navel), Ma Huang (Ephedrae Herba, remove roots), Nong Po (Magnoliae Officinalis Cortex, processed with ginger juice), Ben (Ligustici Rhizoma et Radix), Shao Yao (Paeoniae Radix), Zhi Ke (Aurantii Fructus, stir-fried, remove pith), Chai Hu (Bupleuri Radix), Ze Xie (Alismatis Rhizoma), Xi Xin (Asari Radix et Rhizoma), Fang Feng (Saposhnikoviae Radix, remove rhizome), Bai Zhu (Atractylodis Rhizoma), Huo Xiang (Agastaches Herba), Ban Xia (Pinelliae Rhizoma), Wu Zhu Yu (Evodiae Fructus, washed with decoction), Cang Zhu (Atractylodis Rhizoma), Gan Cao (Glycyrrhizae Radix et Rhizoma) (each half liang).
Chop the above ingredients. Take 5 qian per dose, add 1.5 cups of water, boil to obtain 0.8 cup, remove dregs, and take hot. Re-boil the remaining dregs and take on an empty stomach.
Although these two formulas treat epidemics without distinguishing Yin/Yang, they are suitable for cases with excess cold and exterior pathogenic factors.
[Danxi] When everyone suffers from similar symptoms, it is called Tian Xing Shi Yi (Seasonal Epidemic). There are formulas suitable for tonification, dispersing, or descending.
Da Huang (Rhei Radix et Rhizoma), Huang Qin (Scutellariae Radix), Huang Lian (Coptidis Rhizoma), Ren Shen (Ginseng Radix), Jie Geng (Platocodonis Radix), Fang Feng (Saposhnikoviae Radix), Ren Zhong Huang (Humanis Excrementum Purificatum), Hua Shi (Talcum), Xiang Fu (Cyperi Rhizoma), Cang Zhu (Atractylodis Rhizoma).
Make pills with Qu paste. Take 50-70 pills per dose. Administer with decoctions based on Qi, Blood, or Phlegm differentiation. For Qi deficiency, send down with Si Jun Zi Tang. For Blood deficiency, send down with Si Wu Tang. For excessive Phlegm, send down with Er Chen Tang. For severe heat, send down with fresh urine mixed with the previous medicine.
[Ben Cao] Fen Qing (Urine Sediment): In the twelfth lunar month, cut Dandan Bamboo, remove green skin, soak to extract juice. Treats Tian Xing, mania due to heat, febrile diseases, poisoning, malignant sores, and mushroom toxicity. Soak Gleditsia Sinensis Fruit and Sugarcane in the juice to treat Tian Xing febrile diseases.
[Danxi] Resolves all disasters and diseases. Use 5 liang of Fen Cao (Licorice Root), finely chop, lightly stir-fry. Grind with appropriate amount of non-intoxicating wine according to the patient's capacity. Remove dregs and take warm. Profuse diarrhea will occur shortly, expelling toxins. Even if extremely thirsty, do not drink water; drinking water makes rescue difficult.
The above three formulas are suitable for cases with excess heat and interior pathogenic factors.
[Jiegu] Xiong Huang Wan treats epidemics and prevents contagion.
Xiong Huang (Realgar, 1 liang, ground), Chi Xiao Dou (Vigna umbellata Seed, stir-fried until cooked), Dan Shen (Salviae Miltiorrhizae Radix), Gui Jian Yu (Eucommiae Ramulus? Note: Traditionally Araliae Chinensis Ramus or similar, here likely Eucommiae or specific anti-parasitic herb, WHO term often linked to Artemisia or similar context, but literal is Arrow Branch Feather - usually refers to *Eucommiae Ramulus* or *Artemisiae Annuae Herba* in some contexts, strictly "Gui Jian Yu" is *Eucommiae Ramulus* in modern pharmacopoeia but historically varied. Here kept as Gui Jian Yu), each 2 liang.
Grind into fine powder, mix with refined honey to make pills the size of paulownia seeds. Take 5 pills daily on an empty stomach with warm water. One can share bed and clothes with the sick without contagion.
[Huo Ren Shu] Wuchengzi Yinghuo Wan primarily wards off epidemic diseases, evil qi, ghosts, tigers, wild wolves, snakes, vipers, bees, scorpions, various poisons, weapons, blades, thieves, and凶害 (violent harm).
Ying Huo (Lampyris), Gui Jian Yu (Eucommiae Ramulus, remove skin), Ji Li (Tribuli Fructus) (each 1 liang), Xiong Huang (Realgar), Ci Huang (Orpiment) (each 2 liang), Fan Shi (Alumen, 1 liang, roasted until liquid evaporates), Ling Yang Jiao (Saiga Tatarica Cornu), Duan Zao Hui (Furnace Ash), Tie Chui Bing (Iron Hammer Handle, charred at the striking end, 1.5 fen).
Grind the above nine ingredients into powder. Mix with egg yolk and one rooster comb to form pills the size of apricot kernels. Sew into triangular bags, place 5 pills inside, wear on the left arm, or hang on the door.
If spring should be warm but clear qi is suppressed, excess pathogen resides in the Liver; Sheng Ma Jie Ji Tang is the primary formula. (Formula seen in Warm Disease section.) If summer should be hot but cold qi suppresses it, excess pathogen resides in the Heart; choose Tiao Zhong Tang, She Gan Tang, or Ban Xia Gui Zhi Gan Cao Tang.
Tiao Zhong Tang treats sudden cold suppressing intense heat in early summer/autumn, knotting in the four limbs, causing high fever and headache. Cold injuring the Stomach causes diarrhea, possibly bloody, watery, or red stools, high fever, dizziness, rapid pulse; purgation is indicated.
Da Huang (Rhei Radix et Rhizoma, peeled, 3 fen), Huang Qin (Scutellariae Radix), Shao Yao (Paeoniae Radix), Ge Gen (Puerariae Lobatae Radix), Jie Geng (Platocodonis Radix), Fu Ling (Poria, peeled), Ben (Ligustici Rhizoma et Radix, select authentic; if unavailable, use Chuan Xiong), Bai Zhu (Atractylodis Rhizoma), Gan Cao (Glycyrrhizae Radix et Rhizoma, honey-fried) (each half liang).
Chop the above. Take 5 qian per dose, add 1.5 cups of water, boil to 1 cup, wait a while, then take again. Stop when loose bowels are achieved. Reduce dose for children. (Not suitable for deficiency-cold, no high fever, only diarrhea, or cholera-like symptoms.)
She Gan Tang (Formula seen in Aphonia section.) Ban Xia Gui Zhi Gan Cao Tang (Formula seen in Sore Throat section.)
If autumn should be cool but turns excessively hot, suppression leads to excess pathogen in the Lung; use Bai Hu Jia Cang Zhu Tang or Yin Chen Zhi Tiao Wu Ling San. (Bai Hu Cang Zhu Tang seen in Summer-Heat section, Wu Ling San seen in Thirst section.)
[Danxi] Winter-Warm disease occurs when there is qi out of season. In deep winter, gentlemen should store energy but instead emit it outward; use tonifying herbs combined with exterior-releasing herbs.
Formula for Ren Zhong Huang:
Take a bamboo tube, keep the nodes at both ends. Make a hole in one node, put Gan Cao inside, plug the hole with bamboo/wood nail, immerse in a fecal pit for one month. Take out, dry, and use to treat Plague Toxin. (Use this single herb, added to tonifying and exterior-releasing herbs, decoct and take together.)
[Huo Ren Shu] If winter should be cold but turns excessively warm, suppression leads to excess pathogen in the Kidney; use Wei Rui Tang. (Formula seen in Wind-Dampness section.)