治肾精不足, 虚火炎上, 腰膝痿软, 骨热酸痛, 足
跟痛, 小便淋秘或不禁, 遗精梦泄, 水泛为痰, 自汗, 盗汗, 亡血消
渴,头目眩运, 耳聋齿摇, 尺脉虚大者.
熟地黄八两 山茱萸四两 白茯苓三两 干山药四两 牡丹皮三两
泽泻三两, , 右为末, 炼蜜丸, 如桐子大, 空心淡盐汤下.
【集注】柯琴曰: 肾虚不能藏精, 坎宫之火无所附而妄行, 下无以奉
肝木升生之令, 上绝其肺金生化之源. 地黄禀甘寒之性, 制熟则味厚
,是精不足者补之以味也, 用以大滋肾阴, 填精补髓, 壮水之主. 以
泽泻为使, 世或恶其泻肾而去之, 不知一阴一阳者, 天地之道; 一开
一阖者, 动静之机. 精者属癸, 阴水也, 静而不走, 为肾之体; 溺者
属壬, 阳水也, 动而不居, 为肾之用. 是以肾主五液, 若阴水不守,
则真水不足, 阳水不流, 则邪水泛行. 故君地黄以密封蛰之本, 即佐
泽泻以疏水道之滞也. 然肾虚不补其母, 不导其上源, 亦无以固封蛰
之用. 山药凉补, 以培癸水之上源, 茯苓淡渗, 以导壬水之上源. 加
以茱萸之酸温, 借以收少阳之火, 以滋阴厥之液. 丹皮辛寒, 以清少
阴之火, 还以奉少阳之气也. 滋化源, 奉生气, 天癸居其所矣. 壮水
制火, 特其一端耳.
【按】五行皆一, 惟火有二, 君火, 相火也. 君火为心经之火, 君主
一身之火也. 相火为肾中之火, 宣布一身之火也. 使君火无相火, 则
不能宣布诸火, 以奉生身之本. 相火无君火, 则不能君主诸火, 以制
其妄行之灾. 故李杲立内伤劳倦, 火乘土位之论 , 以心火有余, 用
升阳气, 泻阴火朱砂安神等药, 而未及心火之不足者, 以前人已有归
脾,养心等方也. 震亨立阳常有余, 阴常不足之论, 以肾火有余, 用
补阴, 补天等药, 而未及肾火之不足者, 以前人已有肾气, 桂附地黄
汤丸也. 根据本方加附子, 肉桂, 名桂附地黄丸, 治两尺脉弱, 相火不
足,虚羸少气, 王冰所谓益火之原, 以消阴翳者是也. 加黄柏, 知母
,名知柏地黄丸, 治两尺脉旺, 阴虚火动, 午热骨痿, 王冰所谓壮水
之主, 以制阳光者是也. 经云: 阴平阳秘, 精神乃治. 若阴阳偏胜,
则疾病丛生. 夫肾取象乎坎, 阳藏于阴之藏也. 不独阴盛阳衰, 阳畏
其阴而不敢附, 即阴衰阳盛, 阴难藏阳亦无可根据, 虽同为火不归原,
而其为病则异也. 故于肾药中加桂, 附, 壮阳胜阴, 使阳无所畏, 而
自归原矣. 加知柏补阴秘阳, 使阳有所贮, 而自归藏矣. 世人但知以
桂,附引火归原, 不知以知, 柏平阴秘阳, 举世皆蒙其误, 故震亨特
立补阴之论, 以辟以火济火之非, 而未达其旨者, 从而诽之, 良可叹
也.
治疗肾精亏虚,虚火上炎,腰膝酸软无力,骨骼发热酸痛,足跟疼痛,小便淋漓涩痛或失禁,遗精及梦中泄精,水液代谢失常化为痰饮,自汗,盗汗,失血,消渴病,头晕目眩,耳聋,牙齿松动,尺脉虚弱而大的病症。
熟地黄八两,山茱萸四两,白茯苓三两,干山药四两,牡丹皮三两,泽泻三两。以上六味药研为细末,用炼蜜制成丸剂,大小如梧桐子大,空腹时用淡盐水送服。
【集注】柯琴说:肾虚不能藏精,肾中命门之火(坎宫之火)失去依附而妄行,向下无法奉养肝木升发生发的功能,向上断绝了肺金生化之源。地黄禀受甘寒的性质,制成熟地后味道醇厚,这是“精不足者补之以味”的道理,用来大滋肾阴,填精补髓,壮旺真水之主。以泽泻为使药,世人有的厌恶它泻肾而将其去掉,却不知道一阴一阳是天地运行的规律;一开一阖是动静变化的机理。精属于癸水,是阴水,静止而不流动,是肾的本体;尿属于壬水,是阳水,流动而不居留,是肾的功能。所以肾主五液,如果阴水不守,则真水不足;如果阳水不流,则邪水泛滥。因此用熟地黄作为君药来密封固摄肾的根本,同时佐以泽泻来疏通水道的滞塞。然而肾虚如果不补其母(脾土),不引导其上源(肺气),也无法巩固封藏的作用。山药性凉而补,用以培补癸水之上源;茯苓性淡而渗利,用以引导壬水之上源。加上山茱萸的酸温之性,借以收敛少阳相火,以滋养厥阴肝木之液。牡丹皮辛寒,用以清泄少阴心火,从而奉养少阳之气。滋生化之源,奉养生气,天癸就能安居其位。壮水制火,只是其中的一个方面罢了。
【按语】五行之中,每一行只有一个,唯独火有两个,即君火和相火。君火是心经之火,君主一身之火。相火是肾中之火,宣布一身之火。如果君火没有相火的配合,就不能宣布诸火,以奉养生命之本。如果相火没有君火的统帅,就不能君主诸火,以制止其妄行的灾祸。所以李杲提出内伤劳倦、火乘土位的理论,针对心火有余,使用升阳气、泻阴火的朱砂安神等药物,而没有涉及心火不足的情况,因为前人已有归脾汤、养心汤等方剂。朱震亨提出阳常有余、阴常不足的理论,针对肾火有余,使用补阴丸、补天大造丸等药物,而没有涉及肾火不足的情况,因为前人已有肾气丸、桂附地黄汤丸等方剂。在本方基础上加入附子、肉桂,名为桂附地黄丸,治疗两尺脉弱,相火不足,身体虚弱瘦弱、气息短少,这就是王冰所说的“益火之原,以消阴翳”。加入黄柏、知母,名为知柏地黄丸,治疗两尺脉旺,阴虚火动,午后发热、骨骼痿软,这就是王冰所说的“壮水之主,以制阳光”。经文说:“阴平阳秘,精神乃治。”如果阴阳偏胜,则疾病丛生。肾取象于坎卦,是阳藏于阴中的脏器。不仅阴盛阳衰时,阳畏惧阴而不敢依附;就是阴衰阳盛时,阴难以藏阳,阳也无可依托,虽然都称为火不归原,但其所导致的病症却不同。所以在补肾药中加入桂枝、附子,壮阳胜阴,使阳无所畏惧,而自然回归本源。加入知母、黄柏,补阴秘阳,使阳有所贮藏,而自然回归潜藏。世人只知道用桂枝、附子引火归原,不知道用知母、黄柏平阴秘阳,举世皆受此误导,所以朱震亨特意立补阴之论,以驳斥以火济火的错误观点,但不理解其中旨意的人,反而诽谤他,实在令人叹息。
Treats conditions of Kidney Essence deficiency, with deficient fire flaring upward, soreness and weakness of the waist and knees, bone heat and aching pain, heel pain, dysuria or urinary incontinence, spermatorrhea and nocturnal emission, water metabolism disorder transforming into phlegm, spontaneous sweating, night sweats, blood loss, Xiao Ke (Wasting and Thirsting syndrome), dizziness and vertigo, deafness, loose teeth, and a Chi pulse that is deficient and large.
Shu Di Huang (Prepared Rehmanniae Radix) 8 liang, Shan Zhu Yu (Corni Fructus) 4 liang, Bai Fu Ling (Poria) 3 liang, Gan Shan Yao (Dioscoreae Rhizoma) 4 liang, Mu Dan Pi (Moutan Cortex) 3 liang, Ze Xie (Alismatis Rhizoma) 3 liang. The above six herbs are ground into fine powder, mixed with refined honey to make pills, sized like tung tree seeds, taken on an empty stomach with light salt water.
[Collected Notes] Ke Qin said: Kidney deficiency fails to store essence, causing the Fire of the Kan Palace (Mingmen Fire) to lose its attachment and act recklessly. Downward, it fails to nourish the Liver Wood's ascending and generating function; upward, it severs the source of generation for Lung Metal. Di Huang possesses a sweet and cold nature; when processed into Shu Di Huang, its flavor becomes rich. This follows the principle of "nourishing deficiency with flavor," used to greatly nourish Kidney Yin, fill essence and supplement marrow, and strengthen the master of True Water. Ze Xie is used as an envoy herb. Some people dislike its draining effect on the Kidney and remove it, not realizing that one Yin and one Yang constitute the Way of Heaven and Earth; one opening and one closing constitute the mechanism of motion and stillness. Essence belongs to Gui Water, which is Yin Water, static and non-flowing, constituting the substance of the Kidney. Urine belongs to Ren Water, which is Yang Water, moving and non-abiding, constituting the function of the Kidney. Therefore, the Kidney governs the five fluids. If Yin Water does not remain, True Water is insufficient; if Yang Water does not flow, pathogenic water overflows. Thus, Jun Yao (Chief Herb) Di Huang is used to seal and store the root, while assisting Ze Xie to unblock stagnation in the water pathways. However, if Kidney deficiency is not treated by tonifying its mother (Spleen Earth) or guiding its upper source (Lung Qi), the function of sealing and storing cannot be consolidated. Shan Yao is cool and tonifying, used to cultivate the upper source of Gui Water. Fu Ling is bland and permeating, used to guide the upper source of Ren Water. Added with the sour and warm nature of Zhu Yu, it helps to restrain Shaoyang Ministerial Fire and nourish the fluid of Jueyin Liver. Dan Pi is acrid and cold, clearing Shaoyin Heart Fire, thereby supporting Shaoyang Qi. Nourishing the source of transformation and supporting the breath of life allows Tian Gui to reside in its place. Strengthening Water to control Fire is merely one aspect.
[Commentary] Among the Five Elements, each has only one, except for Fire, which has two: Jun Fire (Monarch Fire) and Xiang Fire (Ministerial Fire). Jun Fire is the Fire of the Heart Meridian, governing the Fire of the whole body. Xiang Fire is the Fire within the Kidney, disseminating the Fire of the whole body. If Jun Fire lacks Xiang Fire, it cannot disseminate the various Fires to support the foundation of life. If Xiang Fire lacks Jun Fire, it cannot govern the various Fires to prevent disasters from reckless action. Therefore, Li Gao proposed the theory of internal injury due to fatigue, where Fire attacks the Earth position. For excess Heart Fire, he used herbs like Zhusha Anshen Wan to raise Yang Qi and drain Yin Fire, but did not address Heart Fire deficiency, as predecessors had already provided formulas like Guipi Tang and Yangxin Tang. Zhu Zhenheng proposed the theory that Yang is often in excess and Yin is often insufficient. For excess Kidney Fire, he used herbs like Buyin Wan and Butian Dazao Wan, but did not address Kidney Fire deficiency, as predecessors had already provided formulas like Shenqi Wan and Guifu Dihuang Wan. By adding Fuzi (Aconiti Lateralis Radix Praeparata) and Rougui (Cinnamomi Cortex) to this formula, it becomes Guifu Dihuang Wan, treating weak Chi pulses, insufficient Ministerial Fire, emaciation, and shortness of breath. This corresponds to Wang Bing's statement: "Tonify the origin of Fire to eliminate Yin shadows." By adding Huangbai (Phellodendri Cortex) and Zhimu (Anemarrhenae Rhizoma), it becomes Zhibai Dihuang Wan, treating vigorous Chi pulses, Yin deficiency with Fire agitation, afternoon fever, and bone weakness. This corresponds to Wang Bing's statement: "Strengthen the master of Water to control the sunlight." The Classic states: "When Yin is balanced and Yang is secure, spirit and vitality are regulated." If Yin and Yang are imbalanced, diseases arise. The Kidney takes the image of Kan, a vessel where Yang is hidden within Yin. Not only when Yin is excessive and Yang is deficient does Yang fear Yin and dare not attach itself; even when Yin is deficient and Yang is excessive, Yin cannot hide Yang, leaving Yang without support. Although both are termed "Fire returning to its origin," the resulting diseases differ. Therefore, in Kidney-tonifying herbs, adding Guizhi (Cinnamomi Ramulus) and Fuzi strengthens Yang to overcome Yin, so that Yang has no fear and naturally returns to its origin. Adding Zhimu and Huangbai nourishes Yin and secures Yang, so that Yang has a reservoir and naturally returns to storage. People only know to use Guizhi and Fuzi to guide Fire back to its origin, unaware that Zhimu and Huangbai balance Yin and secure Yang. The world is misled by this, so Zhu Zhenheng specifically established the theory of nourishing Yin to refute the error of using Fire to assist Fire. Those who fail to understand its purport slander him, which is truly lamentable.