治一切血虚, 血热, 血燥诸证.
当归 熟地各三钱 川芎一钱五分 白芍(酒沙)二钱, 右四味, 水
煎服.
【集注】张璐曰: 四物为阴血受病之专剂, 非调补真阴之的方. 方书
咸谓四物补阴, 遂以治阴虚发热, 火炎失血等证, 蒙害至今. 又专事
女科者, 咸以此汤随证漫加风, 食, 痰, 气等药, 纷然杂出; 其最可
恨者, 不辨热之虚实, 率加知母, 黄柏, 令人久服, 而庸工利其有劫
病之能, 咸乐用之. 殊不知四君子气药, 治上下失血过多, 一切血药
置而不用. 独推独参汤, 童便以固其脱者, 以有形之血, 不能速生,
无形之气, 所当急固也. 昔人有言, 见血休治血, 必先调其气. 又云
:四物汤不得补气药, 不能成阳生阴长之功. 诚哉言也! 然此汤伤寒
火邪解后, 余热留于血分, 至夜微热不除, 或合柴胡, 或加桂枝, 靡
不应手辄效, 不可没其功也.
柯琴曰: 经云: 心生血, 肝藏血. 故凡生血者, 则究之于心; 调血者
,当求之于肝也. 是方乃肝经调血之专剂, 非心经生血之主方也. 当
归甘温和血, 川芎辛温活血, 芍药酸寒敛血, 地黄甘平补血. 四物具
生长收藏之用, 故能使营气安行经隧也. 若血虚加参耆, 血结加桃仁
,红花, 血闭加大黄, 芒硝, 血寒加桂, 附, 血热加芩, 连; 欲行血
去芍, 欲止血去芎, 随所利而行之, 则又不必拘于四矣. 若妇人数脱
其血, 故用以调经种子. 如遇血崩, 血晕等证, 四物不能骤补, 而反
助其滑脱, 则又当补气生血, 助阳生阴长之理. 盖此方能补有形之血
于平时, 不能生无形之血于仓猝, 能调阴中之血, 而不能培真阴之本
,为血分立法, 不专为女科套剂也. 王好古治妇女, 不论内伤, 外感
,胎前, 产后, 随证加二味于四物中, 名曰六合, 未免任意牵强.
治疗一切血虚、血热、血燥等证候。
当归、熟地黄各三钱,川芎一钱五分,白芍(酒炒)二钱,以上四味药,用水煎煮后服用。
【集注】张璐说:四物汤是治疗阴血受病的专用方剂,并非调补真阴的确切方子。医书中都说四物汤能补阴,于是用它来治疗阴虚发热、火炎失血等证候,至今仍在蒙蔽害人。另外,专门从事妇科的医生,都随意在这个汤剂中加入祛风、消食、化痰、理气等药物,杂乱无章地出现;其中最令人痛恨的是,不辨别热的虚实,就随意加入知母、黄柏,让人长期服用,而庸医贪图它有控制病势的能力,都乐于使用它。殊不知对于上下失血过多的一切情况,应当将各种补血药搁置不用,唯独推崇独参汤,配合童便来固护正气以防脱证,因为有形之血不能迅速生成,无形之气应当紧急固护。古人曾说,见到出血不要只治血,必须先调理气机。又说:四物汤如果不配合补气药,就不能达成“阳生阴长”的功效。这确实是至理名言!然而此汤在伤寒火邪解除后,余热留存在血分,导致夜间微热不退,或者配合柴胡,或者加入桂枝,没有不立即见效的,不能抹杀它的功效。
柯琴说:《内经》讲:心主生血,肝主藏血。所以凡是生血的,就要探究于心;凡是调血的,就要求之于肝。这个方子是肝经调血的专用方剂,不是心经生血的主方。当归味甘性温以和血,川芎味辛性温以活血,芍药味酸性寒以敛血,地黄味甘性平以补血。这四味药具备生长收藏的作用,所以能使营气在经脉中安稳运行。如果血虚加人参、黄芪,血结加桃仁、红花,血闭加大黄、芒硝,血寒加桂枝、附子,血热加黄芩、黄连;想要行血就去掉芍药,想要止血就去掉川芎,根据有利之处灵活变通,那么就不必拘泥于这四味药了。如果妇女多次失血,所以用此方调经助孕。如果遇到血崩、血晕等证候,四物汤不能快速补血,反而可能助长滑脱之势,这时又应当遵循补气生血、助阳生阴长的道理。大概此方能平时补充有形的血,不能在仓促间生成无形的血,能调和阴中之血,但不能培补真阴的根本,它是为血分立法,并非专为妇科设立的固定套方。王好古治疗妇女病,不论内伤、外感、胎前、产后,都在四物汤中加入两味药,命名为六合,未免有些任意牵强。
Treats all conditions of blood deficiency, blood heat, and blood dryness.
Danggui (Radix Angelicae Sinensis), Shudi (Prepared Radix Rehmanniae) each 3 qian; Chuanxiong (Rhizoma Chuanxiong) 1.5 qian; Baishao (Radix Paeoniae Alba, wine-fried) 2 qian. The above four herbs are decocted in water and taken orally.
[Collected Annotations] Zhang Lu said: Siwu Tang (Four Substance Decoction) is a specialized formula for treating diseases of Yin-blood, but it is not the precise formula for tonifying True Yin. Medical texts generally claim that Siwu Tang tonifies Yin, leading to its use in treating conditions such as Yin-deficiency fever and hemorrhage due to flaming fire, which has been misleading and harmful to this day. Furthermore, practitioners specializing in gynecology often arbitrarily add wind-dispelling, food-resolving, phlegm-resolving, and Qi-regulating herbs to this decoction according to symptoms, resulting in chaotic prescriptions; what is most detestable is that they fail to distinguish between excess and deficiency of heat, yet rashly add Zhi Mu (Rhizoma Anemarrhenae) and Huang Bo (Cortex Phellodendri), causing patients to take them for long periods. Quacks, attracted by their ability to forcibly suppress disease, readily employ them. Little do they know that for massive hemorrhage from above or below, all blood-tonifying herbs should be set aside, and only Dushen Tang (Single Ginseng Decoction) combined with Tongbian (Child's Urine) should be advocated to secure the collapse, because formed blood cannot be generated quickly, whereas formless Qi must be urgently secured. As the ancients said, when encountering bleeding, do not merely treat the blood; first, regulate the Qi. It is also said: Without Qi-tonifying herbs, Siwu Tang cannot achieve the merit of "Yang generating Yin." Indeed, these are true words! However, after the resolution of pathogenic fire in Shanghan (Cold Damage), residual heat may remain in the blood level, causing slight fever at night that does not subside. In such cases, combining it with Chaihu (Radix Bupleuri) or adding Guizhi (Ramulus Cinnamomi) yields immediate results. Its efficacy should not be overlooked.
Ke Qin said: The Classic states: "The Heart generates blood, and the Liver stores blood." Therefore, for the generation of blood, one should investigate the Heart; for the regulation of blood, one should seek the Liver. This formula is a specialized agent for regulating blood in the Liver meridian, not the primary formula for generating blood in the Heart meridian. Danggui is sweet and warm to harmonize blood; Chuanxiong is acrid and warm to invigorate blood; Shaoyao is sour and cold to astringe blood; Dihuang is sweet and neutral to tonify blood. These four substances possess the functions of growth, flourishing, harvesting, and storing, thus enabling Ying-Qi (Nutritive Qi) to flow smoothly through the meridians. If there is blood deficiency, add Renshen (Radix Ginseng) and Huangqi (Radix Astragali); if there is blood stasis, add Taoren (Semen Persicae) and Honghua (Flos Carthami); if there is blood obstruction, add Dahuang (Radix et Rhizoma Rhei) and Mangxiao (Natrii Sulfas); if there is blood cold, add Guizhi (Ramulus Cinnamomi) and Fuzi (Lateralis Radix Aconiti Preparata); if there is blood heat, add Huangqin (Radix Scutellariae) and Lianqiao (Fructus Forsythiae). To promote blood circulation, remove Shaoyao; to stop bleeding, remove Chuanxiong. Act according to what is beneficial, and one need not be rigidly confined to these four herbs. For women who frequently lose blood, this formula is used to regulate menstruation and facilitate conception. However, in cases of metrorrhagia (uterine bleeding) or syncope due to blood loss, Siwu Tang cannot rapidly replenish blood and may instead exacerbate slipping and collapsing; in such instances, one should follow the principle of tonifying Qi to generate blood and assisting Yang to grow Yin. Generally, this formula can tonify formed blood during normal times but cannot generate formless blood in emergencies; it can regulate blood within Yin but cannot cultivate the root of True Yin. It establishes laws for the blood level and is not merely a stereotyped prescription exclusively for gynecology. Wang Haogu treated women's diseases, regardless of internal injury, external contraction, antenatal, or postnatal conditions, by adding two herbs to Siwu Tang, naming it Liuhe Tang (Six Harmonies Decoction), which was somewhat arbitrary and forced.