附: 加减诸汤 治阳明病, 脉浮而紧, 咽燥口苦,
腹满而喘, 发热汗出, 不恶寒, 反恶热, 身重烦躁, 心中愦愦, 怵惕
懊??, 目疼鼻干, 不得卧.
栀子 ( 擘 ) 十四枚 香豉 ( 绵裹 ) 四合, 右二味, 以水四升, 先
煮栀子, 得二升半; 纳豉, 煮取一升半, 去滓, 分二服. 温进一服,
得吐止后服. 若少气者, 加甘草二两. 若呕者, 加生姜三两. 若下后
心烦腹满, 起卧不安者, 去香豉加厚朴四两, 枳实四枚. 若医以丸药
下之, 身热不去, 心中结痛, 去香豉加干姜二两. 若身热发黄者, 去
香豉加甘草一两, 黄柏二两.
【集注】柯琴曰: 太阳以心腹为里, 阳明以心腹为表. 盖阳明之里是
胃实, 不特发热恶热, 目痛鼻干, 汗出身重, 谓之表; 一切虚烦虚热
,咽燥口苦舌胎, 腹满烦躁不得卧, 消渴而小便不利, 凡在胃之外者
,悉是阳明之表也. 仲景制汗剂, 是开太阳表邪之出路, 制吐剂是引
阳明表邪之出路, 所以太阳之表宜汗不宜吐, 阳明之表当吐不当汗,
太阳当汗而反吐之, 便见自汗出不恶寒, 饥不能食, 朝食暮吐, 欲食
冷食, 不欲近衣等证, 此太阳转属阳明之表法, 当栀子豉汤吐之. 阳
明当吐而不吐, 反行汗下, 温针等法, 以致心中愦愦, 怵惕懊??, 烦
躁舌胎等证, 然仍在阳明之表, 仍当栀子豉汤主之. 栀子苦能涌泄,
寒能胜热, 其形像心, 又赤色通心, 故主治心中上, 下一切证. 豆形
像肾, 又黑色入肾, 制而为豉, 轻浮上行, 能使心腹之浊邪上出于口
,一吐而心腹得舒, 表里之烦热悉解矣. 所以然者, 急除胃外之热,
不致胃家之实, 即此栀豉汤为阳明解表之圣剂矣. 热伤气者少气, 加
甘草以益气, 虚热相搏者多呕, 加生姜以散邪. 若下后而心腹满, 起
卧不安, 是热已入胃, 便不当吐, 故去香豉. 屎未燥硬, 不宜复下,
故只用栀子以除烦, 佐枳朴以泄满, 此两解心腹之妙, 又小承气之轻
剂也. 若以丸药下之, 身热不去, 知表未解也, 心中结痛, 知寒留于
中也. 表热里寒, 故任栀子之苦以除热, 倍干姜之辛以逐寒, 而表热
自解, 里寒自除. 然非吐不能达表, 故用此以探吐之, 此又寒热并用
,为和中解表之剂矣. 内外热炽, 肌肉发黄, 必须苦甘之剂以调之 ,
柏皮, 甘草色黄而润, 助栀子以除内烦而解外热, 形色之病, 仍假形
色以通之. 此皆用栀豉加减以御阳明表证之变幻也. 夫栀子之性, 能
屈曲下行, 不是上涌之剂, 惟豉之腐气上蒸心肺, 能令人吐耳. 观瓜
蒂散必用豉汁和服, 是吐在豉而不在栀也. 栀子干姜汤去豉用姜, 是
取其横开. 栀子厚朴汤, 以枳朴易豉, 是取其下泄. 似皆不欲上越之
义,虽苦亦能作涌, 然非探吐不能吐也. 病人旧微溏者不可与, 则栀
子之性自明矣.
附:加减诸汤
治疗阳明病,脉象浮而紧,咽喉干燥、口苦,腹部胀满且喘息,发热出汗,不恶寒反而怕热,身体沉重、烦躁不安,心中烦乱郁闷,惊恐懊恼,眼睛疼痛、鼻干,无法安卧。
栀子(掰开)十四枚,香豉(用绵布包裹)四合。以上两味药,用水四升,先煮栀子,取汁二升半;加入香豉,再煮至一升半,滤去药渣,分两次温服。第一次温服后,如果引起呕吐,则停止服用后面的药。如果气短者,加甘草二两。如果呕吐者,加生姜三两。如果经过泻下治疗后出现心烦、腹部胀满、坐卧不安的,去掉香豉,加厚朴四两、枳实四枚。如果医生误用丸药泻下,导致身热不退、心中结聚疼痛的,去掉香豉,加干姜二两。如果身体发热并出现发黄的,去掉香豉,加甘草一两、黄柏二两。
【集注】柯琴说:太阳经以心腹为里,阳明经以心腹为表。大概阳明经的“里”是指胃中实证,不仅发热怕热、眼痛鼻干、汗出身体沉重被称为“表”;凡是虚烦、虚热、咽燥口苦舌苔异常、腹部胀满烦躁不能安卧、口渴且小便不利等,凡是在胃腑之外的症状,都属于阳明经的“表”。张仲景制定发汗剂,是为了给太阳经表邪提供出路;制定催吐剂,是为了给阳明经表邪提供出路。所以太阳经的表证宜发汗而不宜催吐,阳明经的表证应当催吐而不宜发汗。太阳经应当发汗却反而使用催吐法,就会出现自汗出、不恶寒、饥饿但不能进食、早晨吃晚上吐、想吃冷食、不喜欢靠近衣物等症状,这是太阳经病转属阳明经表证的方法,应当用栀子豉汤催吐。阳明经应当催吐却不催吐,反而使用发汗、泻下、温针等方法,导致心中烦乱郁闷、惊恐懊恼、烦躁舌苔异常等症状,但这仍然属于阳明经的表证,仍应当用栀子豉汤主治。栀子味苦能涌泄,性寒能胜热,其形状像心,又因赤色通心,所以主治心中及上下的一切病症。豆的形状像肾,又因黑色入肾,制成豆豉后,性质轻浮上行,能使心腹中的浊邪向上从口中排出,一次呕吐后心腹得以舒缓,表里的烦热全部解除。之所以这样,是因为急除胃腑之外的热邪,就不会导致胃家形成实证,因此这个栀豉汤就是阳明经解表的圣剂。热邪伤气导致气短,加甘草以益气;虚热相搏导致多呕吐,加生姜以散邪。如果泻下后心腹胀满,坐卧不安,说明热邪已经入胃,就不应当再催吐,所以去掉香豉。大便尚未燥硬,不宜再次泻下,所以只用栀子来除烦,佐以枳实、厚朴来泄满,这是两解心腹之妙的妙方,也是小承气汤的轻剂。如果用丸药泻下,身热不退,说明表证未解;心中结聚疼痛,说明寒邪留滞于中焦。表热里寒,所以任栀子之苦以除热,倍用干姜之辛以逐寒,表热自然解除,里寒自然消除。然而不用催吐法不能通达表邪,所以用此方来试探催吐,这又是寒热并用,作为调和中和、解除表证的方剂。内外热势炽盛,肌肉发黄,必须用苦甘性质的方剂来调理,黄柏皮和甘草颜色黄而滋润,辅助栀子来清除内烦并解除外热,针对形色的病变,仍借助形色来疏通。这些都是通过加减栀豉汤来应对阳明经表证变幻的方法。栀子的药性,能够屈曲下行,并不是上涌的药剂,只有豆豉的腐气上蒸心肺,才能使人呕吐。看瓜蒂散必须用豆豉汁调和服用,说明催吐的作用在于豆豉而不在栀子。栀子干姜汤去掉豆豉改用生姜,是取其横向开通的作用。栀子厚朴汤,用枳实、厚朴代替豆豉,是取其向下泄下的作用。似乎都不主张向上涌越的意义,虽然苦味也能产生涌吐作用,但如果不采用探吐的方法就不能引起呕吐。病人平时大便微溏的不可给予此方,那么栀子的药性就显而易见了。
Appendix: Various Decoctions with Modifications
Treating Yangming disease, characterized by a floating and tight pulse, dryness of the throat and bitter taste in the mouth, abdominal fullness with panting, fever with sweating, aversion to cold absent but aversion to heat present, heaviness of the body, irritability, mental restlessness (Xin Zhong Kui Kui), palpitations and remorsefulness (Chu Ti Ao Nao), eye pain and nasal dryness, and inability to sleep.
Zhi Zi (Gardeniae Fructus) [broken] 14 pieces; Xiang Chi (Fermented Sojae Semen Nigrum) [wrapped in cotton cloth] 4 he. The above two ingredients are boiled in 4 sheng of water. First, boil Zhi Zi until the liquid reduces to 2.5 sheng; then add Xiang Chi and boil until 1.5 sheng remains. Strain the dregs, divide into two doses, and take warm. After taking the first dose, if vomiting occurs, discontinue subsequent doses. If there is shortness of breath (Shao Qi), add Gan Cao (Glycyrrhizae Radix et Rhizoma) 2 liang. If there is vomiting, add Sheng Jiang (Zingiberis Rhizoma Recens) 3 liang. If after purgation, there is irritability, abdominal fullness, and restlessness (Qi Wo Bu An), remove Xiang Chi and add Hou Po (Magnoliae Officinalis Cortex) 4 liang and Zhi Shi (Aurantii Fructus Immaturus) 4 pieces. If a physician mistakenly used pill-based purgatives, resulting in persistent fever and a knotted pain in the heart region (Xin Zhong Jie Tong), remove Xiang Chi and add Gan Jiang (Zingiberis Rhizoma) 2 liang. If there is fever accompanied by jaundice (Fa Huang), remove Xiang Chi and add Gan Cao (Glycyrrhizae Radix et Rhizoma) 1 liang and Huang Bo (Phellodendri Cortex) 2 liang.
[Collected Annotations] Ke Qin stated: In Taiyang disease, the heart and abdomen are considered the interior; in Yangming disease, the heart and abdomen are considered the exterior. Essentially, the "interior" of Yangming refers to gastric excess (Wei Shi). Not only are symptoms such as fever, aversion to heat, eye pain, nasal dryness, sweating, and body heaviness termed "exterior"; all conditions involving empty irritability (Xu Fan), empty heat, dry throat, bitter taste, abnormal tongue coating, abdominal fullness, irritability, insomnia, thirst with difficult urination, etc., that exist outside the stomach organ, are all considered the "exterior" of Yangming. Zhang Zhongjing formulated diaphoretic agents to provide an exit for pathogenic factors in the Taiyang exterior, and emetic agents to provide an exit for pathogenic factors in the Yangming exterior. Therefore, Taiyang exterior syndromes should be treated with diaphoresis rather than emesis, while Yangming exterior syndromes should be treated with emesis rather than diaphoresis. If Taiyang requires diaphoresis but emesis is used instead, symptoms such as spontaneous sweating, absence of aversion to cold, hunger without ability to eat, morning intake with evening vomiting, desire for cold food, and dislike of being near clothing will appear. This represents the method of Taiyang transforming into Yangming exterior syndrome, which should be treated with Zhi Zi Chi Tang (Gardenia and Fermented Soybean Decoction) to induce emesis. If Yangming requires emesis but it is not performed, and instead diaphoresis, purgation, or warm needle therapy are used, leading to mental restlessness, palpitations, remorsefulness, irritability, and abnormal tongue coating, these symptoms still belong to the Yangming exterior and should still be primarily treated with Zhi Zi Chi Tang. Zhi Zi is bitter and can induce emesis and purgation, and cold in nature to overcome heat. Its shape resembles the heart, and its red color connects to the heart, so it treats all conditions affecting the heart region and upper/lower areas. The bean shape resembles the kidney, and black enters the kidney; when processed into Chi (fermented soybean), it becomes light and floats upward, enabling turbid pathogens in the heart and abdomen to emerge from the mouth. One episode of emesis relieves the heart and abdomen, resolving all exterior and interior irritability and heat. This is because urgently removing heat outside the stomach prevents the formation of gastric excess; thus, this Zhi Zi Chi Tang is the supreme agent for resolving the exterior of Yangming. Heat damaging Qi causes shortness of breath; adding Gan Cao tonifies Qi. Empty heat clashing with deficiency causes frequent vomiting; adding Sheng Jiang disperses pathogens. If after purgation there is heart and abdominal fullness with restlessness, the heat has entered the stomach, so emesis is inappropriate; hence, Xiang Chi is removed. Since the stool is not yet dry and hard, further purgation is unsuitable; thus, only Zhi Zi is used to remove irritability, assisted by Zhi Shi and Hou Po to drain fullness. This is a subtle method to resolve both heart and abdominal issues, serving as a mild version of Xiao Cheng Qi Tang. If pill-based purgatives were used, persistent fever indicates the exterior is unresolved; knotted pain in the heart indicates cold lingering in the middle jiao. With exterior heat and interior cold, one relies on the bitterness of Zhi Zi to clear heat and doubles the pungency of Gan Jiang to drive out cold, thereby naturally resolving exterior heat and eliminating interior cold. However, since emesis is required to reach the exterior, this formula is used to probe for emesis, representing a combination of cold and heat to harmonize the middle and resolve the exterior. When internal and external heat are blazing, causing yellowing of the muscles, bitter-sweet agents must be used to regulate. Huang Bo Pi and Gan Cao are yellow and moistening, assisting Zhi Zi to remove internal irritability and resolve external heat; diseases of form and color are addressed by utilizing corresponding forms and colors. These are all modifications of Zhi Zi Chi Tang to manage the variations of Yangming exterior syndromes. The nature of Zhi Zi allows it to descend curving downward; it is not an emetic agent itself. Only the fermented aroma of Chi steaming upward to the heart and lungs can induce vomiting. Observing Gua Di San (Melon Seed Powder), which must be taken mixed with Chi juice, shows that the emetic effect lies in Chi, not Zhi Zi. In Zhi Zi Gan Jiang Tang, removing Chi and using Jiang takes advantage of horizontal opening. In Zhi Zi Hou Po Tang, replacing Chi with Zhi Shi and Hou Po takes advantage of downward drainage. These seem to avoid upward surging meanings. Although bitter flavors can also cause emesis, without probing for emesis, vomiting cannot be induced. Patients with a history of loose stools should not receive this formula, clarifying the nature of Zhi Zi.