桂枝三钱 芍药(酒焙)二钱 甘草(炙)二钱 黄芩(酒炒)三钱 生姜三片 大
枣(擘)二枚
右水煎,去滓温服,无时,日二、三服。本方加干姜,名阴旦汤。
甘草(炙)四两 干姜(炮)二两
右二味,以水三升,煮取一升五合,去滓,分温再服。
芍药四两 甘草(炙)四两
右二味,以水三升,煮取一升五合,去滓,分温再服。
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伤寒吐、下后,发汗,虚烦,脉甚微,八、九日心下痞□,□下痛,气上冲咽喉,眩
冒,经脉动惕者,久而成痿。
【按】
「八、九日心下痞□,□下痛,气上冲咽喉」三句,与上下文义不属,必是错简。注
家因此三句,皆蔓衍支离,牵强注释。不知此证,总因汗出过多,大伤津液而成,当
用补气补血益筋壮骨之药,经年始可愈也。
【注】
伤寒吐下后,复发其汗,治失其宜矣,故令阳气阴液两虚也。阴液虚,故虚烦;阳气
虚,故脉微;阳气微而不升,故目眩冒;阴液虚而不濡,故经脉动惕也。阳气阴液亏
损,久则百体失所滋养,故力乏筋软而成痿矣。
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伤寒六、七日,大下后,寸脉沉而迟,手足厥逆,下部脉不至,咽喉不利,唾脓血,
泄利不止者,为难治,麻黄升麻汤主之。
【注】
伤寒六、七日,邪传厥阴,厥热胜复之时,医不详审阴阳,而大下之,致变中寒下竭
之坏证。中寒故寸脉沉迟,手足厥逆;下竭故尺脉不至,泄利不止也。盖未下之前,
阳经尚伏表热,大下之后,则其热乘虚下陷,内犯厥阴,厥阴经循喉咙,贯膈注肺,
故咽喉不利,唾脓血也。此为阴阳错杂,表里混淆之证,若温其下,恐助上热,欲清
其上,愈益中寒,仲景故以此汤主之,正示人以阴阳错杂为难治,当于表里上下求治
法也。盖下寒上热,固为难温,里寒无汗,还宜解表,故用麻黄升麻汤,以解表和里
,清上温下,随证治之也。
【集注】
程知曰:言厥逆有因于误下致变者也。凡伤寒热炽者,其阴必虚,六、七日虽当传里
之时,设表证仍在而大下之,则阴伤而阳亦陷。寸脉沉迟,手足厥冷,下利不止,伤
其阳而气内陷也;下部脉不至,咽喉不利吐脓血,伤其阴而热内逼也。一下之误,既
伤其阳,复伤其阴,故难治,与麻黄升麻汤,以升阳调下,清热滋阴。盖传经热邪,
从外入于内者,仍当从内出于外也,故曰:汗出愈。
喻昌曰:寸脉沉而迟,明是阳去入阴之故,非阳气衰微可拟。故虽手足厥冷,下部脉
不至,泄利不止,其不得为纯阴无阳可知。况咽喉不利,唾脓血,又阳邪抟阴上逆之
征验,所以仲景特于阴中提出其阳,得汗出而错杂之邪尽解矣。
桂枝三钱,芍药(经酒烘焙)二钱,甘草(经蜜炙)二钱,黄芩(经酒炒)三钱,生姜三片,大枣(掰开)两枚。
以上药材加水煎煮,滤去药渣,温服,不限固定时间,每日服用二至三次。本方若加入干姜,则名为阴旦汤。
甘草(经蜜炙)四两,干姜(经炮制)二两。
以上两味药,加水三升,煎煮至取汁一升五合,滤去药渣,分两次温服。
芍药四两,甘草(经蜜炙)四两。
以上两味药,加水三升,煎煮至取汁一升五合,滤去药渣,分两次温服。
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伤寒病经过催吐或泻下治疗后,又发汗,导致虚烦,脉象极其微弱;八九日后出现心下痞塞、胁下疼痛、气上冲咽喉、头晕目眩、经脉跳动颤抖等症状,日久将发展为痿证。
【按语】
“八九日心下痞塞、胁下疼痛、气上冲咽喉”这三句,与上下文义不连贯,必定是竹简错乱所致。注家因此三句,都进行了牵强附会、支离破碎的注释。不知道此证总因出汗过多,严重损伤津液而成,应当使用补气补血、益筋壮骨的药物,经过一年左右才能痊愈。
【注解】
伤寒病经过催吐和泻下后,再次发汗,治疗失当,导致阳气和阴液双重虚弱。阴液虚弱,所以出现虚烦;阳气虚弱,所以脉象微弱;阳气微弱不能上升,所以出现头晕目眩;阴液虚弱不能濡养,所以经脉跳动颤抖。阳气和阴液亏损,日久全身失去滋养,所以乏力筋软而形成痿证。
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伤寒六七天,经过猛烈泻下后,寸脉沉而迟,手足厥冷,下部脉摸不到,咽喉不利,唾脓血,泄利不止的,属于难治之症,用麻黄升麻汤主治。
【注解】
伤寒六七天,邪气传入厥阴经,处于厥热胜复的阶段,医生不详审阴阳情况,而进行猛烈泻下,导致变为中寒下竭的坏证。中寒所以寸脉沉迟,手足厥冷;下竭所以尺脉不至,泄利不止。大概在下法之前,阳经尚潜伏表热,猛烈泻下之后,热邪乘虚下陷,内犯厥阴经。厥阴经循行喉咙,贯穿膈肌注入肺脏,所以咽喉不利,唾脓血。这是阴阳错杂、表里混淆的病证,如果温补下部,恐怕助长上部之热;想要清解上部之热,又会加重中部之寒。张仲景因此用此汤主治,正是提示人们阴阳错杂为难治之证,应当在表里上下寻求治疗方法。大概下寒上热,固然难以温补,里寒无汗,还应当解表,所以用麻黄升麻汤,以解表和里,清上温下,随证治疗。
【集注】
程知说:这里说的是厥逆有因误下导致变证的。凡是伤寒热势炽盛的,其阴必虚,六七天虽然是将传里的时期,假设表证仍在而猛烈泻下,则阴伤而阳亦陷入。寸脉沉迟,手足厥冷,下利不止,是伤了阳气而气机内陷;下部脉不至,咽喉不利吐脓血,是伤了阴液而热邪内逼。一次下法的错误,既伤了阳,又伤了阴,所以难治,给予麻黄升麻汤,以升举阳气、调理下部,清热滋阴。大概传经的热邪,从外入于内的,仍应当从内出于外,所以说:出汗后痊愈。
喻昌说:寸脉沉而迟,明显是阳气去而入阴的缘故,不是阳气衰微可以比拟的。所以虽然手足厥冷,下部脉不至,泄利不止,可知其并非纯阴无阳。况且咽喉不利,唾脓血,又是阳邪搏结于阴并上逆的征象验证,所以张仲景特意在阴证中提出其阳气,得汗出而错杂之邪尽解矣。
Guizhi Tang (Cinnamon Twig Decoction) variant: Guizhi (Cinnamon Twig) 3 qian, Shaoyao (White Peony Root) [roasted with wine] 2 qian, Gancao (Licorice Root) [honey-fried] 2 qian, Huangqin (Scutellaria Root) [stir-fried with wine] 3 qian, Shengjiang (Fresh Ginger) 3 slices, Dazao (Jujube Fruit) [split open] 2 pieces.
Decoct the above ingredients in water, remove the dregs, and take warm at any time, twice or three times a day. If Ganjiang (Dried Ginger) is added to this formula, it is named Yindan Tang (Yin Dawn Decoction).
Gancao (Licorice Root) [honey-fried] 4 liang, Ganjiang (Dried Ginger) [pao-processed] 2 liang.
Take the above two herbs, add 3 sheng of water, decoct to obtain 1.5 sheng of liquid, remove the dregs, and divide into two doses to be taken warm.
Shaoyao (White Peony Root) 4 liang, Gancao (Licorice Root) [honey-fried] 4 liang.
Take the above two herbs, add 3 sheng of water, decoct to obtain 1.5 sheng of liquid, remove the dregs, and divide into two doses to be taken warm.
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After Shanghan (Cold Damage) has been treated with emesis or purgation, followed by sweating, deficiency vexation occurs, the pulse is extremely faint; after eight or nine days, epigastric fullness/stuffiness, pain below the costal region, qi rushing up to the throat, dizziness, and twitching/trembling of the meridians occur, which may eventually develop into Wei syndrome (flaccidity syndrome).
[Commentary]
The phrases "after eight or nine days, epigastric fullness/stuffiness, pain below the costal region, qi rushing up to the throat" do not align with the context and are likely due to misplaced bamboo slips. Commentators have thus provided forced and disjointed interpretations for these lines. In reality, this condition arises primarily from excessive sweating causing severe damage to body fluids. It should be treated with herbs that tonify Qi and blood, nourish tendons, and strengthen bones, and recovery may take about a year.
[Annotation]
In Shanghan, after emesis and purgation, administering sweat-inducing therapy again is inappropriate, leading to dual deficiency of Yang Qi and Yin fluids. Deficiency of Yin fluids causes deficiency vexation; deficiency of Yang Qi causes a faint pulse. When Yang Qi is weak and fails to ascend, dizziness and vertigo occur; when Yin fluids are deficient and fail to moisten, twitching and trembling of the meridians occur. Long-term depletion of Yang Qi and Yin fluids leads to loss of nourishment throughout the body, resulting in weakness and soft tendons, forming Wei syndrome (flaccidity syndrome).
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In Shanghan, after six or seven days, following aggressive purgation, if the cun (inch) pulse is deep and slow, hands and feet are cold, the radial pulse at the lower position is imperceptible, there is throat discomfort, expectoration of pus and blood, and unceasing diarrhea, this is difficult to treat and should be managed with Mahuang Shengma Tang (Ephedra and Ma-Huang Decoction).
[Annotation]
In Shanghan, on the sixth or seventh day, as pathogenic factors transmit to the Jueyin (Lesser Yin) stage, characterized by alternating cold and heat, if the physician fails to carefully examine Yin and Yang and administers aggressive purgation, it results in a complicated syndrome of middle-cold and lower exhaustion. Middle-cold manifests as deep and slow cun pulses and cold extremities; lower exhaustion manifests as an imperceptible chi (cubit) pulse and unceasing diarrhea. Prior to purgation, latent heat existed in the Yang channels; after aggressive purgation, this heat sinks downward due to deficiency, invading the Jueyin channel. The Jueyin channel traverses the throat, passes through the diaphragm, and connects to the lungs, hence throat discomfort and expectoration of pus and blood. This is a syndrome of mixed Yin and Yang, and confused interior and exterior. Warming the lower part may exacerbate upper heat, while clearing upper heat may worsen middle cold. Zhang Zhongjing uses this formula to illustrate that mixed Yin and Yang syndromes are difficult to treat, requiring therapeutic strategies addressing both exterior/interior and upper/lower aspects. Since there is lower cold and upper heat, warming alone is difficult; since there is interior cold without sweating, releasing the exterior is still indicated. Thus, Mahuang Shengma Tang is used to release the exterior and harmonize the interior, clear the upper and warm the lower, treating according to the specific presentation.
[Collected Annotations]
Cheng Zhi states: This discusses cases of Jue-ni (cold limbs) caused by complications from erroneous purgation. In cases where Shanghan heat is intense, Yin is inevitably deficient. Although the sixth or seventh day is typically when transmission to the interior occurs, if exterior symptoms persist and aggressive purgation is administered, Yin is damaged and Yang collapses inward. Deep and slow cun pulses, cold extremities, and unceasing diarrhea indicate damage to Yang Qi and inward collapse of Qi; an imperceptible lower pulse, throat discomfort, and expectoration of pus and blood indicate damage to Yin fluids and internal pressure from heat. One error in purgation damages both Yang and Yin, making it difficult to treat. Mahuang Shengma Tang is given to raise Yang Qi, regulate the lower, clear heat, and nourish Yin. Generally, heat pathogens transmitted from exterior to interior should be expelled from interior to exterior, hence it is said: "recovery follows sweating."
Yu Chang states: A deep and slow cun pulse clearly indicates Yang Qi retreating into Yin, not merely Yang Qi deficiency. Therefore, despite cold extremities, an imperceptible lower pulse, and unceasing diarrhea, it cannot be considered a pure Yin syndrome without Yang. Moreover, throat discomfort and expectoration of pus and blood are signs of Yang pathogens clashing with Yin and regurgitating upward. Thus, Zhang Zhongjing specifically extracts Yang Qi from within the Yin syndrome, allowing the mixed pathogens to be resolved completely through sweating.