麻黄(去节)二两 附子(炮去皮,破八片)一枚 甘草(炙)二两
右三味,以水七升,先煮麻黄一两沸,去上沫,内诸药,煮取三升,去滓,温服一升
,日三服。
【集解】
柯琴曰:彼太阳病而脉反沉,便用四逆以急救其里,是里寒阴盛也。此少阴脉而表反
热,便于表剂中加附子以预固其阳,是表热阳衰也。夫以发热无汗,太阳之表脉沉,
但欲寐,少阴之里,设用麻黄开腠理,细辛散浮热,而无附子以固元阳,则太阳之微
阳外亡。惟附子与麻黄并用,则寒邪散而阳不亡,此里病及表,脉沉而当发汗者,与
病在表,脉浮而发汗者,径庭也。若表微热,则受寒亦轻,故以甘草易细辛而微发其
汗,甘以缓之,与辛以散之者,又少间矣。
@@@
少阴病,脉微,不可发汗,亡阳故也。阳已虚,尺脉弱涩者,复不可下之。
【注】
少阴病,脉微,虽有发热,亦为少阴里寒外热,非太阳发热者可比,故不可发汗,发
汗则亡阳。然阳已虚,津液已涸,即见少阴口燥咽干可下之证,若尺脉弱涩者,复不
可下之,又恐亡阴也。
【集注】
方有执曰:微者,阳气不充,故曰无阳,无阳则化不行,故汗不可发也。尺以候阴,
弱涩者,阴血不足也,故谓复不可下,其当亟行温补,又可知矣。
程应旄曰:少阴多自利证,人固无肯轻下者。但拈出「尺脉弱涩」字,则少阴之有大
承气汤证,其尺脉必强而滑,已伏见于此处矣。
@@@
病人脉阴阳俱紧,反汗出者,亡阳也,此属少阴,法当咽痛,而复吐利。
【注】
病人脉阴阳俱紧发热无汗者,太阳伤寒证也;发热汗出不止者,太阳亡阳证也。今脉
紧无热而反汗出,此属少阴。然少阴证,法当咽痛而复吐利也。上条脉微无汗,不可
发汗者,是以脉为主也;此条有汗脉紧,不可发汗者,是以证为主也。从脉从证,不
可不察。
【集注】
程知曰:阴阳俱紧,伤寒之脉也,法当无汗,而反汗出,太阳之阳外亡也。若以少阴
亡阳之证,而认为太阳中风之证,则误矣。少阴之寒上逼,则咽痛而吐,下逼则下利
也。
@@@
少阴病,脉紧,至七、八日,自下利,脉暴微,手足反温,脉紧反去者为欲解也,虽
烦下利,必自愈。
【注】
此承上条互发其义,以别阴阳寒热也。少阴病,脉沉微细,寒邪脉也;脉沉数细,热
邪脉也。若脉紧汗出,是少阴寒虚证也;今脉紧无汗,乃少阴寒实证也。因循至七、
八日之久,而自下利,若寒实解,则脉必紧去而暴微,其证必手足由冷而反温,是知
邪随利去,为欲解也。故此时虽烦下利,乃阴退阳回,故知其必自愈也。
【集注】
方有执曰:紧,寒邪也。自下利脉暴微者,阴寒内泻也。故谓手足为反温,言阳回也
。阳回则阴退,故谓紧反去,为欲解也。夫寒邪在阴而脉紧,得自利脉暴微,手足温
,紧去为欲解者,犹之邪在阳脉数而热,得汗出脉和身凉数去,为欲愈之意,同阴阳
胜复之机也。
程应旄曰:脉于利后顿变紧而为微,手足于利后变不温而为温,则微非诸微亡阳之微
,乃紧去人安之微。盖以从前之寒,已从下利而去,故阳气得回而欲解也,虽烦下利
必自愈。
@@@
少阴病,得之一、二日,口中和,其背恶寒者,当灸之,附子汤主之。
【注】
背恶寒为阴阳俱有之证,如阳明病无大热,口燥渴,心烦背微恶寒者,乃白虎加人参
汤证也。今少阴病但欲寐,得之二、三日,口中不燥而和,其背恶寒者,乃少阴阳虚
之背恶寒,非阳明热蒸之背恶寒也。故当灸之,更主以附子汤,以助阳消阴也。口燥
、口和,诚二者之确征矣。
【集注】
程知曰:言初得之证,口中和,不渴、不燥,全无里热也。『内经』曰:背为阳,背
恶寒则阳虚阴盛,寒深可知。若风寒在表而恶寒,则一身尽寒矣。灸之以助阳消阴,
与附子汤以温经散寒。论中云:伤寒无大热口燥渴,心烦背微恶寒者,白虎汤加人参
主之。彼是阳热乘阴虚而内陷之恶寒,与此之阴寒盛者不同。阳入阴者,则口燥心烦
,阴寒盛者,则不能销铄津液,故口中和。
张璐曰:太阳表气大虚,邪气得入犯少阴,故得之一、二日,尚背恶寒不发热,此阴
阳两亏,较之两感,更自不同。两感表里皆属热邪,犹堪发表攻里,此则内外皆属虚
寒,无邪热可以攻击。惟当温经补阳,以温补其不足,更灸关元以辅助之。虽其证似
缓于发热脉沉,而危殆尤甚焉。
汪琥曰:此条论仲景不言当灸何穴。常器之云:当灸鬲俞、关元穴,背俞第三行。郭
壅云:此有错字,当是灸鬲俞、关元穴也。鬲俞是背俞第二行穴。按鬲俞实系背俞部
第二行穴,然常器之所云第三行穴者,当是鬲关,非鬲俞也。『图经』云:鬲关二穴
在第七椎下,两旁相去各三寸陷中,正坐取之,足太阳气脉所发,专治背恶寒,脊强
,俯仰难,可灸五壮。盖少阴中寒,必由太阳而入,故宜灸其穴。又关元一穴在腹部
中行脐下三寸,足三阴、任脉之会,可灸百壮。常器之所谓灸鬲关者,是温其表以散
外邪;灸关元者,是温其里以助其元气也。
@@@
少阴病,身体痛,手足寒,骨节痛,脉沉者,附子汤主之。
【注】
此承上条详举其证,互发其义,以出其治也。身体痛,表里俱有之证也,如太阳病脉
浮发热,恶寒身痛,手足热,骨节痛,是为表寒,当主麻黄汤,发表以散其寒。今少
阴病,脉沉无热,恶寒身痛,手足寒,骨节痛,乃是里寒,故主附子汤,温里以散寒
也。
【集注】
方有执曰:少阴肾也,肾主骨,寒淫则痛。
程应旄曰:身体痛,手足寒,骨节痛,太阳伤寒同有此证也。以脉沉辨之,沉属阴寒
重着所致,里阴有余,表阳不足,故以附子汤主之。
麻黄(去节)二两 附子(炮去皮,破八片)一枚 甘草(炙)二两
以上三味药,用水七升,先煮麻黄至一沸,去掉水面上的浮沫,加入其余药物,煎取三升药液,滤去药渣,温服一升,每日服用三次。
【集解】
柯琴说:太阳病而脉象反而沉,就用四逆汤来急救其里证,这是里寒阴盛的表现。此条少阴病脉象而表反热,便在解表剂中加入附子以预先固护其阳气,这是表热阳衰的表现。发热无汗,是太阳表的脉象沉;但想睡觉,是少阴里的表现。如果只用麻黄开泄腠理,细辛发散浮热,而没有附子来固护元阳,那么太阳的微阳就会外亡。只有附子与麻黄并用,才能散寒邪而不使阳气外亡,这是里病及表,脉沉而应当发汗的情况,与病在表、脉浮而发汗的情况截然不同。如果表有微热,说明受寒也轻,所以用甘草代替细辛来微微发汗,甘味药能缓和药性,与辛味药发散药力相比,又稍微温和一些。
@@@
少阴病,脉象微弱,不可发汗,因为会亡阳的缘故。阳气已经虚弱,尺脉弱涩的,也不可攻下。
【注】
少阴病,脉象微弱,虽然有发热,也是少阴里寒外热,不能与太阳发热相提并论,所以不可发汗,发汗就会导致亡阳。然而阳气已经虚弱,津液已经枯竭,即使出现少阴口燥咽干等可下的证候,如果尺脉弱涩的,也不可以攻下,又恐怕导致亡阴。
【集注】
方有执说:脉微,是阳气不充盛,所以说无阳,无阳则气化不行,所以汗不可发。尺脉候阴,弱涩,是阴血不足,所以说也不可以攻下,应当紧急施行温补,也就知道了。
程应旄说:少阴病多自利证,人本来就不会轻易攻下。但特意提出“尺脉弱涩”这几个字,那么少阴病有大承气汤证的,其尺脉必定强而滑,已经隐含在此处了。
@@@
病人脉象寸关尺三部都紧,反而出汗的,是亡阳,这属于少阴病,按照常理应当咽痛,并且伴有呕吐和下利。
【注】
病人脉象寸关尺三部都紧,发热无汗的,是太阳伤寒证;发热汗出不止的,是太阳亡阳证。现在脉紧无热反而出汗,这属于少阴病。然而少阴病,按照常理应当咽痛并且伴有呕吐和下利。上一条脉微无汗,不可发汗的,是以脉象为主;这一条有汗脉紧,不可发汗的,是以症状为主。从脉从证,不可以不仔细考察。
【集注】
程知说:阴阳三部脉都紧,是伤寒的脉象,按理应当无汗,反而出汗,是太阳的阳气外亡。如果把少阴亡阳的证候,误认为太阳中风的证候,那就错了。少阴的寒邪上逼,就会咽痛和呕吐,下逼就会下利。
@@@
少阴病,得病一两天,口中平和,背部怕冷的,应当施灸,用附子汤主治。
【注】
背恶寒是阴阳都有可能出现证候,如阳明病没有大热,口燥渴,心烦背微恶寒的,是白虎加人参汤证。现在少阴病但想睡觉,得病两三天,口中不燥而平和,背部怕冷的,是少阴阳虚的背恶寒,不是阳明热蒸的背恶寒。所以应当施灸,更用附子汤主治,以助阳消阴。口燥、口和,确实是两者的确凿征象。
【集注】
程知说:说的是刚得病的证候,口中平和,不渴、不燥,完全没有里热。《内经》说:背为阳,背恶寒则是阳虚阴盛,寒邪深重可知。如果是风寒在表而恶寒,则全身都会寒冷。施灸以助阳消阴,用附子汤温经散寒。论中说:伤寒没有大热口燥渴,心烦背微恶寒的,用白虎汤加人参主治。那是阳热乘阴虚而内陷的恶寒,与此处的阴寒盛不同。阳入阴者,就会口燥心烦,阴寒盛者,就不能销铄津液,所以口中平和。
张璐说:太阳表气大虚,邪气得入犯少阴,所以得病一两天,还背恶寒不发热,这是阴阳两亏,比之两感证,更加不同。两感表里皆属热邪,还可以发表攻里,这里则内外皆属虚寒,没有邪热可以攻击。只应当温经补阳,以温补其不足,再灸关元穴以辅助它。虽然其证似乎比发热脉沉要缓和一些,但危殆程度尤其严重。
汪琥说:这一条论述仲景没有说应当灸什么穴位。常器之说:应当灸膈俞、关元穴,背俞第三行。郭壅说:这里有错字,应当是灸膈俞、关元穴。膈俞是背俞第二行穴。按膈俞实际是背俞部第二行穴,然而常器之所说的第三行穴,应当是膈关,不是膈俞。《图经》说:膈关二穴在第七椎下,两旁相距各三寸凹陷中,正坐取之,足太阳气脉所发,专治背恶寒,脊强,俯仰困难,可灸五壮。大概少阴中寒,必由太阳而入,所以宜灸其穴。另外关元一穴在腹部中行脐下三寸,足三阴、任脉之会,可灸百壮。常器之所说的灸膈关,是温其表以散外邪;灸关元,是温其里以助其元气。
@@@
少阴病,身体痛,手足寒,骨节痛,脉沉的,附子汤主治。
【注】
此承接上一条详细列举其证候,互相发挥其义,以指出其治疗方法。身体痛,是表里都有的证候,如太阳病脉浮发热,恶寒身痛,手足热,骨节痛,这是表寒,应当主用麻黄汤,发表以散其寒。现在少阴病,脉沉无热,恶寒身痛,手足寒,骨节痛,这是里寒,所以主用附子汤,温里以散寒。
【集注】
方有执说:少阴肾也,肾主骨,寒淫则痛。
程应旄说:身体痛,手足寒,骨节痛,太阳伤寒同样有此证候。以脉象沉来辨别,沉属阴寒重着所致,里阴有余,表阳不足,所以用附子汤主治。
Mahuang (Ephedrae Herba, 麻黄) [devoid of nodes] liang (Chinese ounce), Fuzi (Aconiti Lateralis Radix Praeparata, 附子) [prepared, skin removed, broken into eight pieces] one piece, Gancao (Glycyrrhizae Radix et Rhizoma Praeparata cum Melle, 甘草) [roasted with honey] liang.
The above three ingredients are decocted in seven sheng (Chinese liquid measure) of water. First, boil Mahuang until it boils once, remove the foam on the surface, then add the remaining herbs. Decoct until three sheng remain, filter out the dregs, and take one sheng warm. Administer three times a day.
[Collected Commentary]
Ke Qin stated: In Taiyang disease (Taiyang syndrome), if the pulse is unexpectedly deep, Si Ni Tang (Counterflow Decoction) is used to urgently rescue the interior, indicating an excess of Yin-cold in the interior. In this case of Shaoyin disease (Shaoyin syndrome), where the pulse suggests Shaoyin but there is superficial heat, Fuzi is added to exterior-resolving formulas to preemptively secure Yang Qi, indicating deficient Yang with superficial heat. Fever without sweating corresponds to the deep pulse of Taiyang exterior; lethargy corresponds to Shaoyin interior. If Mahuang were used alone to open the pores and Xixin (Asari Radix, 细辛) to scatter floating heat, without Fuzi to secure the Primordial Yang, the slight Yang of Taiyang would escape outward. Only when Fuzi and Mahuang are used together can cold pathogens be dispersed without losing Yang. This represents interior pathology affecting the exterior, where a deep pulse indicates the need for diaphoresis, which is fundamentally different from exterior pathology with a floating pulse requiring diaphoresis. If there is slight superficial heat, the cold pathogen is light; thus, Gancao replaces Xixin to induce mild diaphoresis. The sweet flavor moderates the action, making it milder than the dispersing action of acrid flavors.
@@@
In Shaoyin disease, if the pulse is faint, diaphoresis is contraindicated because it may lead to the loss of Yang. If Yang is already deficient and the Chi (cun-guan-chi pulse position corresponding to the lower jiao/kidneys) pulse is weak and choppy, purgation is also contraindicated.
[Annotation]
In Shaoyin disease, a faint pulse, even with fever, indicates interior cold with exterior heat (deficient Yang floating outward), which cannot be compared to the fever of Taiyang disease; therefore, diaphoresis is contraindicated as it leads to the loss of Yang. However, if Yang is already deficient and body fluids are exhausted, even if symptoms suitable for purgation such as dry mouth and throat appear, if the Chi pulse is weak and choppy, purgation is still contraindicated to avoid the loss of Yin.
[Collected Commentary]
Fang Youzhi stated: A faint pulse indicates insufficient Yang Qi, hence "no Yang." Without Yang, transformation and movement do not occur, so diaphoresis is impossible. The Chi position reflects Yin; a weak and choppy pulse indicates deficiency of Yin-blood. Thus, purgation is contraindicated, and urgent warming and tonification should be employed.
Cheng Yingmao stated: Shaoyin disease often presents with spontaneous diarrhea, so people generally do not lightly use purgatives. However, by highlighting the "weak and choppy Chi pulse," it implies that in Shaoyin cases requiring Da Cheng Qi Tang (Great Order the Qi Decoction), the Chi pulse must be forceful and slippery, a condition foreshadowed here.
@@@
If a patient's pulse is tight at all positions (Yin and Yang) but they sweat profusely, this indicates the loss of Yang and belongs to Shaoyin disease. According to standard patterns, this should present with sore throat, vomiting, and diarrhea.
[Annotation]
Tight pulses at all positions with fever and no sweating indicate Taiyang Cold Damage syndrome. Fever with continuous sweating indicates Taiyang loss of Yang. Now, a tight pulse without fever but with sweating indicates Shaoyin disease. In Shaoyin disease, the standard presentation includes sore throat, vomiting, and diarrhea. In the previous clause, the faint pulse without sweating made diaphoresis contraindicated based primarily on the pulse. In this clause, the presence of sweating with a tight pulse makes diaphoresis contraindicated based primarily on the symptoms. One must carefully distinguish between relying on the pulse versus the symptoms.
[Collected Commentary]
Cheng Zhi stated: Tightness in all pulse positions is characteristic of Cold Damage, where sweating should not occur. Profuse sweating indicates the external loss of Taiyang Yang. Mistaking Shaoyin loss of Yang for Taiyang Wind Strike would be an error. When Shaoyin cold forces upward, it causes sore throat and vomiting; when it forces downward, it causes diarrhea.
@@@
In Shaoyin disease, after one or two days, if the mouth feels normal and comfortable, but there is aversion to cold in the back, moxibustion should be applied, and Fu Zi Tang (Aconite Decoction) should be administered as the primary treatment.
[Annotation]
Aversion to cold in the back can occur in both Yin and Yang diseases. For example, in Yangming disease, if there is no high fever but dry mouth, thirst, irritability, and slight aversion to cold in the back, it is a Bai Hu Jia Ren Shen Tang (White Tiger Plus Ginseng Decoction) pattern. Here, in Shaoyin disease, with lethargy, occurring after two or three days, if the mouth is not dry but comfortable, and there is aversion to cold in the back, it is aversion to cold due to Shaoyin Yang deficiency, not the aversion to cold caused by Yangming heat steaming. Therefore, moxibustion should be applied, and Fu Zi Tang should be given to assist Yang and dissipate Yin. Dry mouth versus a comfortable mouth are definitive signs distinguishing these conditions.
[Collected Commentary]
Cheng Zhi stated: This describes the initial stage where the mouth is comfortable, not thirsty or dry, indicating no interior heat. The *Neijing* states: "The back is Yang." Aversion to cold in the back indicates Yang deficiency and Yin-cold excess, revealing deep cold. If aversion to cold were due to wind-cold in the exterior, the whole body would feel cold. Moxibustion assists Yang to dissipate Yin, and Fu Zi Tang warms the meridians and scatters cold. The text mentions that in cases of Cold Damage with no high fever, dry mouth, thirst, irritability, and slight aversion to cold in the back, Bai Hu Tang plus Ginseng is used. That is aversion to cold caused by Yang-heat sinking into Yin due to Yin deficiency, which differs from the current case of severe Yin-cold. When Yang enters Yin, there is dry mouth and irritability; when Yin-cold is excessive, it cannot consume body fluids, so the mouth remains comfortable.
Zhang Lu stated: When Taiyang exterior Qi is severely deficient, pathogens enter and attack Shaoyin. Thus, within one or two days, there is aversion to cold in the back without fever. This represents a deficiency of both Yin and Yang, differing significantly from Liang Gan (simultaneous involvement of Taiyang and Shaoyin). In Liang Gan, both exterior and interior involve heat pathogens, allowing for exterior-releasing and interior-purging treatments. Here, both interior and exterior are deficient-cold, with no heat pathogens to attack. Treatment should focus on warming the meridians and tonifying Yang to supplement insufficiency, supplemented by moxibustion at Guan Yuan (CV4). Although the condition seems less acute than fever with a deep pulse, it is more critical.
Wang Hu stated: This clause does not specify which acupoints Zhongjing intended for moxibustion. Chang Qizhi said: Moxi Ge Shu (BL17) and Guan Yuan (CV4). Guo Yong noted a textual error, suggesting it should be Ge Shu (BL17) and Guan Yuan (CV4). Ge Shu is in the second row of Back-Shu points. However, Chang Qizhi's mention of the "third row" likely refers to Ge Guan (BL47), not Ge Shu. The *Tu Jing* states: Ge Guan points are located below the seventh thoracic vertebra, three cun lateral to the midline, in depressions. They are accessed in a sitting position, are exit points of the Foot-Taiyang channel, and specifically treat aversion to cold in the back, stiff spine, and difficulty bending/straightening. Five moxa cones can be applied. Since Shaoyin cold invasion typically enters via Taiyang, these points are appropriate. Guan Yuan is located three cun below the umbilicus on the anterior midline, meeting the Foot-Yin channels and Ren Mai. One hundred moxa cones can be applied. Moxibustion on Ge Guan warms the exterior to scatter external pathogens, while moxibustion on Guan Yuan warms the interior to boost Yuan Qi.
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In Shaoyin disease, with body pain, cold hands and feet, bone and joint pain, and a deep pulse, Fu Zi Tang is the primary treatment.
[Annotation]
This elaborates on the previous clause to clarify the symptoms and treatment. Body pain can occur in both exterior and interior conditions. In Taiyang disease, floating pulse, fever, aversion to cold, body pain, warm hands/feet, and joint pain indicate exterior cold, treated with Ma Huang Tang (Ephedra Decoction) to release the exterior and disperse cold. In Shaoyin disease, however, a deep pulse, absence of fever, aversion to cold, body pain, cold hands/feet, and joint pain indicate interior cold, treated with Fu Zi Tang to warm the interior and disperse cold.
[Collected Commentary]
Fang Youzhi stated: Shaoyin corresponds to the Kidney. The Kidney governs the bones. Excess cold causes pain.
Cheng Yingmao stated: Body pain, cold hands/feet, and joint pain are also seen in Taiyang Cold Damage. Differentiation relies on the deep pulse. Deepness indicates heavy Yin-cold. There is excess Yin in the interior and deficiency of Yang in the exterior; thus, Fu Zi Tang is indicated.