东垣云太阳经病发寒疟阳明经病发为热疟少阳经病发为风疟三阴经病总为温疟此言虽是
但三阴经分说未明凡作于子午卯酉日者少阴疟也寅申巳亥日者厥阴疟也辰戌丑未日者少阴疟
也发于阳分者易治发于阴分者难治
一日一发者受病一月 间日一发者受病半年 三日一发者受病一年 二日连发住一日者
气血俱病
脉诀云疟脉多弦弦迟多寒弦数多热
心法曰疟脉多弦热则弦而数寒则弦而迟亦有病久而脉虚微无力似乎不弦但虚数之中略有
弦而不搏手耳
一疟病子时至午发者邪在气分(属阳) 午至亥时发者邪在血分(属阴)
一邪在阴分夜间发者宜用 夜疟散
一夏秋病疟初因外感内伤阴阳未分寒热交作恶心头疼先宜发散用 藿香正气散 二香散
人
一夏暑汗不出者发为风疟宜发散以解之用 二香散
一太阳经病疟寒多不热者名寒疟宜用 桂枝芍药汤 养胃汤加桂枝
一阳明经病单热不寒者名瘅疟作渴宜用 白虎汤加 柴胡 不渴用 黄芩葛根汤
一少阳经病寒热交作者宜用 小柴胡汤 柴苓汤
一三阳合病寒热甚者宜用 桂枝黄芩汤
一三阴经病寒多热少者名温疟宜用 柴胡桂枝汤
一感时气先热后寒亦名温疟宜用 小柴胡汤加减用
一疟病寒热交作通宜 清脾汤加减用
一疟病日久不愈者名为老疟宜用 老疟饮 四兽饮 四圣散 阿魏丸
一疟发作日久不止元气虚弱脾胃亏损食少自汗先服祛疟饮后用补中益气汤
一疟病热多烦渴者宜用 柴胡栝蒌根汤
一元气盛发五七次不止者宜用截法 常山饮 七宝饮 露星散
一疟病烦热头疼者宜用 柴胡石膏汤
一元气虚发不止者宜用 四圣散 截住后用补中益气汤
一疟病发热作泻者宜用 柴苓汤
一有元气素虚为邪祟所侵寒热如疟状谓之邪疟邪退则止
一治疟病胁下有痰块名曰疟母宜用 鳖甲饮
一疟病烦热作渴大便不通者宜用 大柴胡汤
一痰疟为病胸满恶心有痰寒热者宜用 鬼哭丹
一食疟恶食胸闷或有积块者宜用 阿魏丸 红丸子
一乡野无药处有发疟者用 生姜四两连皮捣汁露过夜和童便温服随效
李东垣曾说:太阳经受邪引发的疟疾表现为寒多热少的寒疟;阳明经受邪引发的疟疾表现为但热不寒的热疟(瘅疟);少阳经受邪引发的疟疾表现为往来寒热的风疟;三阴经受邪引发的疟疾统称为温疟。这种说法虽然大致正确,但对于三阴经疟疾的区分阐述得不够明确。凡是发生在子、午、卯、酉日发作的,属于少阴疟;发生在寅、申、巳、亥日发作的,属于厥阴疟;发生在辰、戌、丑、未日发作的,属于太阴疟(注:原文此处写作“少阴疟”,结合上下文及中医理论,辰戌丑未对应土,属脾/太阴,故此处依理推断为太阴,但翻译时保留原文字面意思并稍作说明或直译,鉴于要求忠实原文,此处直译为“少阴疟”,但在中医逻辑中通常指太阴,此处严格按原文翻译)。在阳分发病的容易治疗,在阴分发病的难以治疗。
每隔一天发作一次的,是患病一个月左右;隔两天发作一次的,是患病半年左右;隔三天发作一次的,是患病一年左右;连续发作两天后停歇一天的,说明气血都受到了病邪侵害。
《脉诀》说:疟疾的脉象大多呈弦脉。脉象弦而迟缓的多为寒证,脉象弦而数急的多为热证。
《心法》说:疟疾的脉象大多呈弦脉。热证则脉弦而数,寒证则脉弦而迟。也有因病日久导致脉象虚微无力,看似不弦,但在虚数之中略微带有弦意,且按之搏动感不强。
有一种疟疾,从子时到午时发作的,病邪在气分(属阳);从午时到亥时发作的,病邪在血分(属阴)。
夏秋季节患疟疾,起初因外感风寒、内伤饮食,导致阴阳失调,寒热交替发作,伴有恶心、头痛,应先宜发散解表,使用藿香正气散或二香散。
太阳经受邪引发的疟疾,恶寒重发热轻的,名为寒疟,适宜使用桂枝芍药汤,或在养胃汤中加入桂枝。
阳明经受邪引发的疟疾,只发热不恶寒的,名为瘅疟,伴有口渴,适宜使用白虎汤加柴胡;若不口渴,使用黄芩葛根汤。
少阳经受邪引发的疟疾,寒热往来的,适宜使用小柴胡汤或柴苓汤。
三阳经合病,寒热症状严重的,适宜使用桂枝黄芩汤。
三阴经受邪引发的疟疾,恶寒重发热轻的,名为温疟,适宜使用柴胡桂枝汤。
感受时行疫气,先发热后恶寒的,也名为温疟,适宜使用小柴胡汤加减服用。
疟疾病程长久不愈的,名为老疟,适宜使用老疟饮、四兽饮、四圣散或阿魏丸。
疟疾发作日久不止,元气虚弱,脾胃亏损,食欲不振,自汗出,应先服用祛疟饮,随后服用补中益气汤。
元气尚盛,发作五七次不止的,适宜采用截疟法,使用常山饮、七宝饮或露星散。
元气虚弱,疟疾发作不止的,适宜使用四圣散截住疟疾,之后服用补中益气汤。
素来元气虚弱,被邪祟侵扰,出现类似疟疾的寒热症状,称为邪疟,邪气退去则停止。
治疗疟疾病程日久,胁下有痰块积聚,名为疟母,适宜使用鳖甲饮。
痰疟致病,胸膈满闷、恶心、有痰、寒热交作的,适宜使用鬼哭丹。
食疟致病,厌恶进食、胸闷或有积块的,适宜使用阿魏丸或红丸子。
乡野无药之处,若有发作者,可用生姜四两,连皮捣汁,露天放置过夜,混合童便温服,随即见效。
Li Dongyuan stated: Malaria caused by pathogenic invasion of the Taiyang (Greater Yang) meridian manifests as cold malaria (Han Nue), characterized by more chills than fever; malaria caused by pathogenic invasion of the Yangming (Bright Yang) meridian manifests as heat malaria (Dan Nue), characterized by fever without chills; malaria caused by pathogenic invasion of the Shaoyang (Lesser Yang) meridian manifests as wind malaria (Feng Nue), characterized by alternating chills and fever; malaria caused by pathogenic invasion of the three Yin meridians is collectively referred to as warm malaria (Wen Nue). Although this statement is generally correct, the differentiation among the three Yin meridians is not clearly explained. Those occurring on Zi, Wu, Mao, or You days belong to Shaoyin malaria; those occurring on Yin, Shen, Si, or Hai days belong to Jueyin malaria; those occurring on Chen, Xu, Chou, or Wei days belong to Shaoyin malaria (Note: Textually "Shaoyin", but contextually often refers to Taiyin in classical theory regarding these earthly branches). Malaria manifesting in the Yang aspect is easy to treat, while that manifesting in the Yin aspect is difficult to treat.
Malaria occurring every other day indicates a disease duration of about one month; occurring every two days indicates a duration of about half a year; occurring every three days indicates a duration of about one year; consecutive occurrence for two days followed by a one-day pause indicates that both Qi and Blood are diseased.
The Mai Jue (Pulse Classic) states: The pulse in malaria is mostly wiry (Xian). A wiry and slow pulse indicates excess cold; a wiry and rapid pulse indicates excess heat.
The Xin Fa (Core Methods) states: The pulse in malaria is mostly wiry. In heat conditions, the pulse is wiry and rapid; in cold conditions, it is wiry and slow. There are also cases where the disease has persisted for a long time, resulting in a deficient, minute, and weak pulse that appears non-wiry, yet within the deficiency and rapidity, there is a slight wiry quality, though it does not feel firm upon palpation.
In one type of malaria, if onset occurs from Zi hour to Wu hour, the pathogen is in the Qi aspect (Yang); if onset occurs from Wu hour to Hai hour, the pathogen is in the Blood aspect (Yin).
For pathogens in the Yin aspect with nocturnal onset, Ye Nue San (Night Malaria Powder) is appropriate.
In summer and autumn, when malaria initially arises from external contraction and internal injury, leading to disharmony of Yin and Yang, alternating chills and fever, accompanied by nausea and headache, dispersing and releasing the exterior should be prioritized using Huoxiang Zhengqi San (Agastache Powder to Regulate the Qi) or Er Xiang San (Two Fragrances Powder).
When summer heat prevents sweating, leading to wind malaria, dispersing methods should be used to resolve the exterior, employing Er Xiang San.
For malaria involving the Taiyang meridian, where chills predominate over fever, named cold malaria, Guizhi Shaoyao Tang (Cinnamon Twig and Peony Decoction) is appropriate, or Gui Zhi may be added to Yangwei Tang (Stomach-Nourishing Decoction).
For malaria involving the Yangming meridian, characterized by fever alone without chills, named Dan malaria, accompanied by thirst, Baihu Tang (White Tiger Decoction) plus Chai Hu (Bupleurum Root) is appropriate; if there is no thirst, Huangqin Gegen Tang (Scutellaria and Pueraria Decoction) is used.
For malaria involving the Shaoyang meridian, characterized by alternating chills and fever, Xiaochaihu Tang (Minor Bupleurum Decoction) or Chai Ling Tang (Bupleurum and Polyporus Decoction) is appropriate.
For combined disease of the three Yang meridians with severe chills and fever, Guizhi Huangqin Tang (Cinnamon Twig and Scutellaria Decoction) is appropriate.
For disease of the three Yin meridians, where chills predominate over heat, named warm malaria, Chaihu Guizhi Tang (Bupleurum and Cinnamon Twig Decoction) is appropriate.
Contracting seasonal epidemic qi, presenting with initial fever followed by chills, also named warm malaria, Xiaochaihu Tang (Minor Bupleurum Decoction) modified is appropriate.
For malaria with alternating chills and fever, Qingpi Tang (Clear Spleen Decoction) modified is generally applicable.
For malaria persisting for a long time without resolution, named old malaria, Laonie Yin (Old Malaria Drink), Six Beasts Drink (Sishou Yin), Four Sages Powder (Sixsheng San), or Awei Wan (Asafoetida Pill) are appropriate.
For prolonged malaria attacks causing deficiency of Yuan Qi (Original Qi), damage to the Spleen and Stomach, poor appetite, and spontaneous sweating, Qunie Yin (Anti-Malaria Drink) should be taken first, followed by Buzhong Yiqi Tang (Tonify the Middle and Augment the Qi Decoction).
For malaria with predominant heat, irritability, and thirst, Chaihu Gualougen Tang (Bupleurum and Trichosanthes Root Decoction) is appropriate.
For robust Yuan Qi with attacks occurring five to seven times without cessation, interception methods are appropriate, using Changshan Yin (Dichroa Root Drink), Qibao Yin (Seven Treasures Drink), or Luxing San (Dew Star Powder).
For malaria with irritability, heat, and headache, Chaihu Shigao Tang (Bupleurum and Gypsum Decoction) is appropriate.
For deficient Yuan Qi with persistent attacks, Sixsheng San (Four Sages Powder) should be used to intercept the malaria, followed by Buzhong Yiqi Tang (Tonify the Middle and Augment the Qi Decoction).
For malaria with fever and diarrhea, Chai Ling Tang (Bupleurum and Polyporus Decoction) is appropriate.
For individuals with inherent Yuan Qi deficiency invaded by evil spirits, presenting with malaria-like chills and fever, termed Evil Malaria (Xie Nue), the symptoms cease when the evil retreats.
To treat prolonged malaria with phlegm masses under the hypochondrium, named Malaria Mother (Nuo Mu), Biejia Yin (Softshell Turtle Drink) is appropriate.
For malaria with irritability, heat, thirst, and constipation, Da Chaihu Tang (Major Bupleurum Decoction) is appropriate.
For Phlegm Malaria presenting with chest fullness, nausea, phlegm, and alternating chills and fever, Guiku Dan (Ghost Cry Elixir) is appropriate.
For Food Malaria presenting with aversion to food, chest oppression, or accumulations, Awei Wan (Asafoetida Pill) or Hongwanzi (Red Pellet) is appropriate.
In rural areas without access to medicine, for malaria outbreaks, use four taels of fresh ginger, crushed with the skin, juice extracted, exposed overnight, mixed with children's urine, and taken warm; efficacy will follow immediately.