（邵应节）
治气血不足，羸弱周痹，肾虚无子，消渴，淋沥，遗精，崩带，痈疮，痔肿等证（周痹，
周身
交。
何首乌（大者，赤、白各一斤去皮，切片，黑豆拌，九蒸九晒） 白茯苓（乳拌） 牛
膝（
半斤）
此足少阴、厥阴药也。何首乌涩精固气，补肝坚肾，为君；茯苓交心肾而渗脾湿；牛膝
强筋骨而益下焦；当归辛温以养血；枸杞甘寒而补水；菟丝子益三阴而强卫气；补骨脂助命
火而暖丹田；此皆固本之药，使荣卫调适，水火相交，则气血太和，而诸疾自已也（何首乌
流传虽久，服者尚寡，明嘉靖间，方士邵应节进此方，世宗服之，连生皇子，遂盛行于世。
昂按∶地黄、何首乌皆君药也，故六味丸以地黄为君，七宝丹以何首乌为君，各有配合，未
可同类而共施也。即有加减，当各根据本方，随病而施损益。今人多以何首乌加入地黄丸中，
合两方
（杨氏）
治脾肾虚寒，血气羸乏，不思饮食，发热盗汗，遗精白浊，肌体瘦弱，牙齿浮痛等证（肾
为先天之根本，脾为后天之根本，二本有伤，则见上项诸证，故未老而先衰，二本既固，则
自康
熟地黄（二两） 山药 牛膝（酒浸） 枸杞（酒浸，两半） 山茱肉 茯苓（乳拌） 杜
仲（
（酒浸） 肉苁
一方茯苓换茯神，加川续断，名打老儿丸（妇人年过百岁，打其老儿子不肯服此丸）。
此手足少阴、足太阴药也。两肾中间有命火，乃先天之真阳，人之曰用云为，皆此火也
。此
能入
水足
茱、五味生肺液而固精；远志、菖蒲通心气以交肾（遗精白浊，由于心肾不交）；大枣补气
益血，润
丹溪去楮实，更名滋阴大补丸（此阴阳平补之剂，而曰滋阴者，肾为阴脏也）。
【邵应节方】
治疗气血不足、身体消瘦虚弱及周身关节疼痛（周痹，指风寒湿邪侵袭全身经络导致的肢体疼痛）、肾气虚导致的不育、消渴病、小便淋漓不尽、遗精、妇女崩漏带下、痈疽疮疡、痔疮肿痛等证候。（注：原文此处有残缺，“周痹”后接“周身交”，意指周身经络气血不通。）
药材组成：
何首乌（选用大的，赤色和白色各一斤，去皮，切片，用黑豆拌炒，经过九次蒸制和九次日晒）
白茯苓（用乳汁拌炒）
牛膝（半斤）
此方属于足少阴肾经和足厥阴肝经的药物。何首乌能涩精固气，补益肝脏，坚固肾脏，作为君药；茯苓能交通心肾并渗除脾脏湿气；牛膝能强健筋骨并补益下焦；当归辛温以养血；枸杞甘寒以滋补肾水；菟丝子能补益肝、脾、肾三阴并增强卫气；补骨脂能助命门之火并温暖丹田；这些都是巩固根本的药物，能使营卫调和适宜，水火既济相交，那么气血就会达到太和的状态，各种疾病自然痊愈。（按语：何首乌流传虽久，但服用者尚少。明代嘉靖年间，方士邵应节将此方进献，明世宗服用后接连生下皇子，于是此方在世间盛行开来。汪昂按：地黄和何首乌都是君药，所以六味丸以地黄为君药，七宝美髯丹以何首乌为君药，各有其配伍原则，不可简单地将同类药物混合施用。即使有加减变化，也应当依据原方，随病情施以增减损益。如今许多人将何首乌加入地黄丸中，合并两方……）
【杨氏方】
治疗脾肾虚寒、气血亏乏、不思饮食、发热盗汗、遗精白浊、身体瘦弱、牙齿浮痛等证候。（注：肾为先天之本，脾为后天之本，若这两个根本受损，就会出现上述诸证，因此未老先衰；若这两个根本稳固了，自然健康长寿。）
药材组成：
熟地黄（二两）
山药
牛膝（酒浸）
枸杞（酒浸，一两半）
山茱萸肉
茯苓（乳拌）
杜仲
（原文此处有残缺，推测为其他药材如巴戟天等，依上下文及还少丹原方补充理解，但仅翻译可见部分）
（酒浸）
肉苁蓉
另一版本将茯苓换为茯神，加入川续断，名为打老儿丸（传说妇人年过百岁，打其老儿子不肯服此丸，形容其功效之神奇或名字由来）。
此方属于手少阴心经、足少阴肾经和足太阴脾经的药物。两肾中间有命门之火，这是先天的真阳，人的日常活动运用，都依赖于此火。
（原文此处有残缺，大致意为药物能入……水足……）
山茱萸、五味子能生津液并固精；远志、石菖蒲能通心气以交通心肾（遗精白浊，多由于心肾不交所致）；大枣能补气益血，润……
[Shao Yingjie's Formula]
Treats conditions such as deficiency of Qi and Blood, emaciation and weakness, generalized arthralgia (Zhou Bi, referring to pain in the limbs caused by invasion of Wind-Cold-Dampness into the whole body's meridians), infertility due to Kidney Deficiency, Xiao Ke (Wasting-Thirst syndrome), dribbling urination, spermatorrhea, leukorrhea and metrorrhagia in women, carbuncles and sores, hemorrhoids, and swelling. (Note: The original text here is fragmented; "Zhou Bi" is followed by "whole body connection," implying blockage of Qi and Blood in the whole body's meridians.)
Ingredients:
He Shou Wu (Polygoni Multiflori Radix Praeparata) (Select large roots, one jin each of red and white varieties, peel, slice, mix with black beans, steam nine times and sun-dry nine times)
Bai Fu Ling (Poria) (Mix with milk and stir-fry)
Niu Xi (Achyranthis Bidentatae Radix) (Half a jin)
This formula consists of herbs belonging to the Foot-Shaoyin Kidney Meridian and Foot-Jueyin Liver Meridian. He Shou Wu astringes essence and consolidates Qi, tonifies the Liver, and strengthens the Kidneys, serving as the Sovereign herb (Jun Yao); Fu Ling facilitates communication between the Heart and Kidneys and leaches out Dampness from the Spleen; Niu Xi strengthens sinews and bones and benefits the Lower Jiao; Dang Gui is pungent and warm to nourish Blood; Gou Qi Zi is sweet and cold to tonify Kidney Water; Tu Si Zi tonifies the Yin of the Liver, Spleen, and Kidney and strengthens Wei Qi (Defensive Qi); Bu Gu Zhi assists Ming Men Fire (Fire of the Gate of Life) and warms the Dan Tian (Elixir Field); these are all herbs that consolidate the root, enabling the harmonious regulation of Ying (Nutritive) and Wei (Defensive) Qi, and the interaction of Water and Fire, thereby achieving Tai He (Great Harmony) of Qi and Blood, causing various diseases to heal spontaneously. (Commentary: Although He Shou Wu has been circulated for a long time, few people take it. During the Jiajing reign of the Ming Dynasty, the alchemist Shao Yingjie presented this formula. Emperor Shizong took it and subsequently had multiple princes born, leading to its widespread popularity. Wang Ang notes: Di Huang and He Shou Wu are both Sovereign herbs. Therefore, Liu Wei Di Huang Wan uses Di Huang as the Sovereign herb, while Qi Bao Mei Ran Dan uses He Shou Wu as the Sovereign herb. Each has its own compatibility principles and should not be simply combined as similar substances. Even with modifications, one should base them on the original formula and adjust according to the disease. Nowadays, many people add He Shou Wu to Di Huang Wan, combining the two formulas...)
[Yang Shi's Formula]
Treats conditions such as Cold-Deficiency of the Spleen and Kidney, deficiency of Qi and Blood, loss of appetite, fever and night sweats, spermatorrhea and turbid urine, emaciation, and floating toothache. (Note: The Kidney is the root of congenital constitution, and the Spleen is the root of acquired constitution. If these two roots are damaged, the aforementioned symptoms appear, leading to premature aging; if these two roots are solidified, health and longevity naturally follow.)
Ingredients:
Shu Di Huang (Rehmanniae Radix Praeparata) (Two liang)
Shan Yao (Dioscoreae Rhizoma)
Niu Xi (Achyranthis Bidentatae Radix) (Soaked in wine)
Gou Qi Zi (Lycii Fructus) (Soaked in wine, 1.5 liang)
Shan Zhu Yu (Corni Fructus)
Fu Ling (Poria) (Mix with milk and stir-fry)
Du Zhong (Eucommiae Cortex)
(Wine-soaked)
Rou Cong Rong (Cistanche Herba)
Another version replaces Fu Ling with Fu Shen (Poria with Hostwood) and adds Chuan Xu Duan (Dipsaci Radix), named Da Lao Er Wan (Legend has it that a woman over a hundred years old beat her old son who refused to take this pill, describing the miraculous nature or origin of the name).
This formula consists of herbs belonging to the Hand-Shaoyin Heart Meridian, Foot-Shaoyin Kidney Meridian, and Foot-Taiyin Spleen Meridian. Between the two kidneys lies the Fire of Ming Men (Gate of Life), which is the True Yang of the congenital constitution. All daily activities and functions of humans rely on this fire.
(The original text here is fragmented, roughly meaning the herbs enter... water suffices...)
Shan Zhu Yu and Wu Wei Zi generate Lung fluid and consolidate essence; Yuan Zhi and Chang Pu (Acori Tatarinowii Rhizoma) unblock Heart Qi to facilitate communication between the Heart and Kidney (Spermatorrhea and turbid urine often result from non-interaction between Heart and Kidney); Da Zao tonifies Qi and nourishes Blood, moistens...
Danxi removed Chu Shi Zi (Broussonetiae Fructus) and renamed it Zi Yin Da Bu Wan (This formula is a balanced tonic for both Yin and Yang, but is called "Nourishing Yin" because the Kidney is a Yin organ).