论曰乳石发动寒热者，以石热壅积，将适失度，阴阳之气，不得和平也。盖阳病发热，
阴病发寒。一于热则偏于阳，一于寒则偏于阴，时寒时热，则营卫交争，阴阳相胜，若伤寒
诸疟之状是也。
治诸石发动，口干，时作寒热，似鬼神病，麦门冬丸方
麦门冬（去心焙五两） 大黄（锉炒） 苦参 葳蕤 栀子仁 五加皮（锉） 黄芩（去
黑心） 犀角（镑） 芍药 升麻 大青（各一两） 甘草（炙三分）
上一十二味，捣罗为末，炼蜜搜和，更捣匀熟，丸如梧桐子大，每食后，以蜜水下十五
丸，渐加至二十丸。
治乳石发动，口干寒热，似鬼神为病。犀角丸方
犀角屑 五加皮（锉） 黄芩（去黑心各一两） 苦参 大黄（锉碎微炒） 芍药（各
一两半） 大青 甘草（炙各三分） 麦门冬（去心焙）
上九味，捣罗为末，炼蜜和丸，如梧桐子大，食后以蜜水下十五丸，渐加至二十丸，早
晨日午晚后各一服。
治乳石发如伤寒，寒热状兼似疟。前胡汤方
前胡（去芦头） 黄芩（去黑心） 甘草（炙锉） 知母（各二两） 牡蛎（熬） 石
膏（各三两）
上六味，粗捣筛，每服四钱匕，以水一盏半，入生姜一枣大切。枣二枚擘破，煎至八分
，去滓温服。
治乳石毒经二三十年，发动为寒热，或栗栗似寒中者，或欲食，或不欲食。若服紫石英
发热者，热闷昏昏喜卧，起便无力。皆腑气所生，脏气不知， 石热燥如战，石硫黄热郁。
如热极者，身并破裂。华佗芍药汤方
芍药 赤茯苓（去黑皮） 人参 蓝实 黄芩（去黑心） 甘草（炙赤各一两） 荠
（二两） 蔓荆子（一升）
上八味，除蔓荆子外，捣为粗末，每服五钱匕，用水四盏，先煮蔓荆子一合，至三盏去
滓。次下药末，煎至一盏半，去滓分温三服。早晨日午晚后，各一服。
治乳石发动，兢战恶寒，或发热如温疟，此为失食忍饥失洗所致，宜此。方
上宜急食冷食，及冷水洗数遍，即愈。
治乳石发，若得时气，冷热不调，动乳者，皆是寒热所致。其状似疟，久不疗，损人性
命。纵服汤药，必是难瘥，宜作生熟汤浴之。方
上以温汤半浴盆，如过热投少冷水解之。即于汤中坐，须臾百节开，寒热之气，皆从毛
孔中出，变作流汗。若心中热闷者，还服少许热汤，即定，久乃出汤，以衣被覆盖睡，豁然
平复。如患大重者，不过三两度也。
论述说：乳石（指含有矿物成分的补益药，多含砷、汞等有毒物质）发动引起寒热症状的，是因为石性燥热壅积体内，加上房事生活失去节制，导致阴阳之气不能平和。一般来说，阳病表现为发热，阴病表现为发冷。如果单纯偏于热，则阳气偏盛；单纯偏于寒，则阴气偏盛；时而寒冷时而发热，则是营气与卫气相互交争，阴阳相互克制，其症状表现如同伤寒和各种疟疾的样子。
治疗各种乳石发动引起的口干、时常出现寒热交替、症状类似鬼神作祟病的麦门冬丸方：
麦门冬（去除心部，焙干，五两）、大黄（切碎炒制）、苦参、葳蕤、栀子仁、五加皮（切碎）、黄芩（去除黑色中心部分）、犀角（镑成薄片）、芍药、升麻、大青（以上各一两）、甘草（蜜炙，三分）。
以上十二味药，捣碎过筛成为粉末，用炼过的蜂蜜调和，再捣匀熟透，制成梧桐子大小的药丸。每次饭后，用蜜水送服十五丸，逐渐增加至二十丸。
治疗乳石发动引起的口干、寒热交替、症状类似鬼神作祟病的犀角丸方：
犀角屑、五加皮（切碎）、黄芩（去除黑色中心部分，各一两）、苦参、大黄（切碎微炒）、芍药（各一两半）、大青、甘草（蜜炙，各三分）、麦门冬（去除心部焙干）。
以上九味药，捣碎过筛成为粉末，用炼过的蜂蜜和成药丸，大小如梧桐子。饭后用蜜水送服十五丸，逐渐增加至二十丸，分别在早晨、中午、日落后各服用一次。
治疗乳石发作像伤寒一样，有寒热症状且类似疟疾的前胡汤方：
前胡（去除芦头）、黄芩（去除黑色中心部分）、甘草（蜜炙切碎）、知母（以上各二两）、牡蛎（熬制）、石膏（以上各三两）。
以上六味药，粗捣后筛选，每次服用四钱匕，用水一盏半，加入生姜一块（切得很大片）、大枣两枚（掰开），煎煮至八分满，去渣温服。
治疗乳石毒经过二三十年，发作引起寒热，或者战栗感觉像受寒的人，或者想吃东西，或者不想吃东西。如果是服用紫石英引起发热的，会感到热闷昏沉喜欢躺着，起来就无力。这些都是腑气所生，脏气不知晓，石热燥烈如颤抖，石硫黄热郁结。如果热极严重，身体甚至会破裂。华佗芍药汤方：
芍药、赤茯苓（去除黑皮）、人参、蓝实、黄芩（去除黑色中心部分）、甘草（蜜炙变红，以上各一两）、荠（二两）、蔓荆子（一升）。
以上八味药，除了蔓荆子外，捣成粗末。每次服用五钱匕，用水四盏，先煮蔓荆子一合，煮至三盏时去渣。然后下入药末，煎煮至一盏半，去渣分三次温服。分别在早晨、中午、日落后各服用一次。
治疗乳石发动，战栗恶寒，或者发热像温疟，这是由于饮食不当、忍饥挨饿或没有洗浴所致，适宜使用此法。方剂：
此时应当立即吃冷的食物，并用冷水清洗身体数遍，即可痊愈。
治疗乳石发作，如果感染了时行疫病，冷热不调，触动乳石的，都是寒热所致。其症状类似疟疾，久不治疗，会损害人的性命。即使服用汤药，也必定难以痊愈，适宜制作生熟汤进行沐浴。方剂：
准备半盆温水，如果过热则投入少量冷水调节温度。随即坐在汤中，片刻之间全身关节舒展，寒热之气都从毛孔中排出，变成流汗。如果心中感到热闷，再喝少许热汤，症状就会安定，很久之后才出汤池，用衣被覆盖睡觉，豁然平复。如果病情非常严重的，不过两三次就可以了。
Commentary states: The onset of cold and heat symptoms caused by "Rushi" (mineral-based tonics, often containing toxic substances such as arsenic and mercury) is due to the accumulation of the hot nature of minerals within the body, combined with immoderate sexual activity, leading to a lack of harmony between Yin and Qi. Generally, Yang diseases manifest as fever, while Yin diseases manifest as chills. If there is an excess of heat, Yang becomes predominant; if there is an excess of cold, Yin becomes predominant. Alternating chills and fever indicate a struggle between Ying (Nutritive Qi) and Wei (Defensive Qi), and a mutual overcoming of Yin and Yang, resembling the symptoms seen in Shanghan (Cold Damage) and various types of Nue (Malaria).
Formula for Maidong Wan (Ophiopogon Pill) to treat various Rushi attacks presenting with dry mouth, intermittent chills and fever, and symptoms resembling possession by spirits:
Maidong (Ophiopogonis Radix, heart removed, roasted, 5 liang), Dahuang (Rhei Radix et Rhizoma, chopped and stir-fried), Kushen (Sophorae Flavescentis Radix), Weirui (Polygonati Odorati Rhizoma), Zhizi Ren (Gardeniae Fructus), Wujia Pi (Acanthopanacis Cortex, chopped), Huangqin (Scutellariae Radix, black center removed), Xijiao (Rhino Ceratostigma, shaved), Shaoyao (Paeoniae Radix), Shengma (Cimicifugae Rhizoma), Daqing (Isatidis Folium or Indigo Naturalis, each 1 liang), Gancao (Glycyrrhizae Radix et Rhizoma, honey-fried, 3 fen).
The above twelve ingredients are crushed, sifted into powder, mixed with refined honey, pounded until uniform and cooked, then formed into pills the size of sophora seeds. Take fifteen pills after each meal, washed down with honey water, gradually increasing to twenty pills.
Formula for Xijiao Wan (Hornicorn Pill) to treat Rushi attacks presenting with dry mouth, chills and fever, and symptoms resembling spirit illness:
Xijiao xie (Rhino Ceratostigma shavings), Wujia pi (Acanthopanacis Cortex, chopped), Huangqin (Scutellariae Radix, black center removed, each 1 liang), Kushen (Sophorae Flavescentis Radix), Dahuang (Rhei Radix et Rhizoma, chopped and slightly stir-fried), Shaoyao (Paeoniae Radix, each 1.5 liang), Daqing (Isatidis Folium or Indigo Naturalis), Gancao (Glycyrrhizae Radix et Rhizoma, honey-fried, each 3 fen), Maidong (Ophiopogonis Radix, heart removed and roasted).
The above nine ingredients are crushed, sifted into powder, mixed with refined honey, and formed into pills the size of sophora seeds. Take fifteen pills after meals, washed down with honey water, gradually increasing to twenty pills. Take one dose each in the morning, at noon, and after sunset.
Formula for Qianhu Tang (Peucedani Decoction) to treat Rushi attacks resembling Shanghan, with chills and fever similar to Nue (Malaria):
Qianhu (Peucedani Radix, rhizome head removed), Huangqin (Scutellariae Radix, black center removed), Gancao (Glycyrrhizae Radix et Rhizoma, honey-fried and chopped), Zhimu (Anemarrhenae Rhizoma, each 2 liang), Muli (Ostreae Concha, calcined), Shigao (Gypsum Fibrosum, each 3 liang).
The above six ingredients are coarsely crushed and sifted. For each dose, take four qianbi (approx. 4-6 grams), add one dan and a half of water, one large piece of fresh ginger (Shengjiang, Zingiberis Rhizoma Recens), and two dates (Dazao, Jujubae Fructus) split open. Decoct until reduced to eight parts, strain, and take warm.
Formula for Huatuo Shaoyao Tang (Huatuo's Peony Decoction) to treat Rushi toxicity persisting for twenty to thirty years, causing chills and fever, trembling as if chilled, appetite loss or lack thereof. If caused by Zhi Yanshi (Purple Quartz) leading to fever, it results in heat oppression, drowsiness, preference for lying down, and weakness upon rising. These arise from Fu organ Qi generation, unknown to Zang organs; the mineral heat is dry and causes trembling, while mineral realgar (Shiliuhuang) causes heat stagnation. In extreme heat, the body may even rupture.
Shaoyao (Paeoniae Radix), Chi Fuling (Poria with Red Skin, black skin removed), Renshen (Ginseng Radix et Rhizoma), Lanshi (Indigo Naturalis or Baphicacanthi Cuspidis Folium et Radix), Huangqin (Scutellariae Radix, black center removed), Gancao (Glycyrrhizae Radix et Rhizoma, honey-fried and reddened, each 1 liang), Ji (Shepherd's Purse, 2 liang), Manjingzi (Vitex Fruit, 1 sheng).
Except for Manjingzi, the above eight ingredients are crushed into coarse powder. For each dose, take five qianbi, use four dan of water. First decoct one he of Manjingzi until reduced to three dan, then strain. Add the coarse powder, decoct until reduced to one dan and a half, strain, and divide into three warm doses. Take one dose each in the morning, at noon, and after sunset.
Treatment for Rushi attacks causing trembling and aversion to cold, or fever resembling Wen Nue (Warm Malaria), caused by improper diet, fasting, or lack of bathing:
Immediately consume cold food and wash the body several times with cold water; this will lead to recovery.
Treatment for Rushi attacks complicated by seasonal epidemic pathogens, where cold and heat are unbalanced, triggering Rushi symptoms. These are caused by cold and heat. The presentation resembles Nue (Malaria); if untreated for long, it damages life. Even with herbal decoctions, cure is difficult. It is advisable to bathe in a mixture of raw and cooked water (temperature-regulated bath).
Prepare half a basin of warm water; if too hot, add cold water to adjust. Sit in the bathwater. After a moment, all joints will relax, and the qi of cold and heat will exit through the pores, transforming into sweating. If there is heat oppression in the heart, drink a small amount of hot water to settle it. Remain out of the bath for a long time, cover with blankets, and sleep; recovery will be sudden and complete. For severe cases, two or three sessions are sufficient.