论曰间日疟者，邪气着于阴，不得与阳气俱出也，卫气昼行于阳，邪气不得出，故必再
会而后发，是以间日乃作也。
治间日疟先寒战后壮热。常山汤方
常山 甘草（炙各三两） 鳖甲（去裙 醋炙一两） 淡竹叶（切三升洗）
上四味。 咀，以酒三升渍之，上复头，安露地，明旦以水七升，重汤内煮，水过半为
度，其酒分五服，未发饮之当吐，吐已不必尽剂。
治间日疟。醇 汤方
大黄（锉炒三分） 甘草（炙） 常山（各一分半）
上三味。 咀，以水三盏，煎取一盏去滓，更以水一盏煎滓，取七分，未发先服 药，
是后煎者，相次服醇药，是前煎者，瘥。
治间日疟。常山酒方
常山（一两） 蒜（独头者一颗去根茎横切） 糯米 黑豆（各一百粒）
上四味。 咀，以清酒一升，病未发前一日，以酒浸药于碗中，以白纸复之，碗上横一
刀，欲发时分三分，先饮一分，如未吐，更服一分，得吐则瘥。
治间日疟。备急一元散方
上烧黑牛尾作灰，酒服方寸匕，日三。
治间日疟发寒热。常山汤方
常山 竹叶（细锉各三分） 秫米（五十粒糯米亦得） 石膏（碎二两）
上四味。粗捣筛，每服五钱匕，以水一盏半，浸药一宿，明旦煎至一盏，去滓温服，未
发前一服，临发再服，当日勿洗漱，勿饮食，并用余药汁。涂五心及胸前头面，药滓置枕边
治间日疟。糯米煮散方
糯米（四十粒） 常山（锉） 乌梅肉（炒） 竹叶（锉） 甘草（炙各半两） 石膏
（一两半碎
上六味。捣罗为散，每服五钱匕，以水一盏半，煎至七分，去滓未发前温服。
治疟间日发。大黄汤方
大黄（生半两） 甘草（炙锉） 常山（锉） 桂（去粗皮各一分）
上四味。粗捣筛，每服五钱匕，水一盏半，煎至七分去滓，未发前温服。
治间日疟。神圣丸方
黑豆（小者二十一粒水浸去皮） 砒霜（研一钱） 大枣（一枚煮去皮核）
上三味。须于重午七夕日修合，同研，丸如豌豆大，以丹砂为衣，合时忌妇人鸡犬见，
于发日早晨，将药一丸，面北香上度过，用冷茶清下，忌热物一复时。
论述说：间日疟，是邪气附着于阴分，不能与卫气同时出于阳分。卫气白天行于阳分，邪气因此无法随之外出，必须等到卫气再次循环汇聚时才会发病，所以每隔一天发作一次。
治疗间日疟，症状表现为先寒战随后高热。常山汤方
常山、甘草（炙制，各三两）、鳖甲（去除裙边，醋炙，一两）、淡竹叶（切碎三升，洗净）
以上四味药。切碎，用酒三升浸泡，容器口覆盖头状物，放置在露天处，次日清晨加入水七升，隔水加热煮至水量剩下一半为度。将药酒分为五次服用，在疾病未发作前饮用，应当引起呕吐，吐完后不必服完剩余的药量。
治疗间日疟。醇药汤方
大黄（锉碎炒制，三分）、甘草（炙制）、常山（各一分半）
以上三味药。切碎，用水三盏煎取一盏药液，去渣；再用一盏水煎煮药渣，取七分药液。在疾病未发作前先服用第一煎的药，随后依次服用第二煎的醇药，这样前面的煎剂就能治愈疾病。
治疗间日疟。常山酒方
常山（一两）、蒜（独头蒜一颗，去根茎横切）、糯米、黑豆（各一百粒）
以上四味药。切碎，用清酒一升，在病发前一天，将药物浸泡在碗中，用白纸覆盖碗口，在碗上横放一把刀。欲发作时分为三份，先饮一份，如果未呕吐，再服一份，若引起呕吐则病愈。
治疗间日疟。备急一元散方
将黑牛尾烧成灰，用酒送服一方寸匕大小的药粉，每日三次。
治疗间日疟发作时的寒热症状。常山汤方
常山、竹叶（细锉，各三分）、秫米（五十粒，糯米也可以）、石膏（捣碎，二两）
以上四味药。粗捣筛过，每次服用五钱匕，用水一盏半，浸泡药物一夜，次日清晨煎至一盏，去渣温服。在疾病未发作前服一次，临发作时再服一次，当天不要洗漱，不要进食饮水，其余药汁涂抹于手心、脚心、胸口及头面部，药渣放在枕头边。
治疗间日疟。糯米煮散方
糯米（四十粒）、常山（锉碎）、乌梅肉（炒制）、竹叶（锉碎）、甘草（炙制，各半两）、石膏（一两半，捣碎）
以上六味药。捣碎过筛制成散剂，每次服用五钱匕，用水一盏半，煎至七分，去渣，在疾病未发作前温服。
治疗疟疾隔日发作。大黄汤方
大黄（生用，半两）、甘草（炙制锉碎）、常山（锉碎）、桂枝（去除粗皮，各一分）
以上四味药。粗捣筛过，每次服用五钱匕，用水一盏半，煎至七分，去渣，在疾病未发作前温服。
治疗间日疟。神圣丸方
黑豆（小的二十一粒，用水浸泡去皮）、砒霜（研细，一钱）、大枣（一枚，煮熟去皮核）
以上三味药。必须在端午节或七夕节配制，共同研磨，制成如豌豆大小的丸药，以朱砂为衣。配制时要忌讳妇女、鸡犬看见。在发病日早晨，面向北方，让药丸经过香火上方，用冷茶送服，忌食热物一个时辰。
Discourse states: Jianri Nue (Intermittent Malaria occurring every other day) occurs when pathogenic factors adhere to the Yin aspect and cannot emerge together with the Wei Qi (Defensive Qi). Since Wei Qi circulates in the Yang aspects during the day, the pathogenic factors are unable to exit; thus, they must wait for a subsequent convergence of Wei Qi before manifesting symptoms, which is why the condition arises every other day.
Treatment for Jianri Nue, characterized by initial chills followed by high fever, utilizes Changshan Tang (Crownvetch Root Decoction).
Ingredients: Hedyotisae Herba (Changshan, 3 liang, processed), Glycyrrhizae Radix et Rhizoma (Gancao, 3 liang, honey-fried), Testudinis Carapax et Plastrum (Biejia, 1 liang, vinegar-processed after removing the skirt), and Lophatheri Herba (Danzhuye, 3 sheng, cut and washed).
Preparation: The four ingredients are coarsely chopped, soaked in 3 sheng of wine, covered, and placed outdoors overnight. At dawn, add 7 sheng of water and simmer over hot water until half the liquid remains. Divide the wine-decoction into five doses. Administer before the onset of symptoms; vomiting is expected. Discontinue administration once vomiting occurs, without needing to consume the entire dose.
For treating Jianri Nue, Chun Yao Tang (Astringent Herb Decoction):
Ingredients: Rhei Radix et Rhizoma (Dahuang, 0.5 fen, crushed and stir-fried), Glycyrrhizae Radix et Rhizoma (Gancao, 0.5 fen, honey-fried), and Hedyotisae Herba (Changshan, 0.5 fen).
Preparation: Coarsely chop the three ingredients. Decoct with 3 zhan of water to obtain 1 zhan of liquid, then strain. Decoct the dregs again with 1 zhan of water to obtain 0.7 zhan. Take the first decoction before the onset of symptoms, followed immediately by the second decoction (the "astringent" medicine). This sequence cures the disease.
For treating Jianri Nue, Changshan Jiu (Crownvetch Root Wine):
Ingredients: Hedyotisae Herba (Changshan, 1 liang), Allii Sativi Bulbus (Suan, one single-clove garlic, root and stem removed, sliced horizontally), Oryzae Fructus Glutinosa (Nuomi, 100 grains), and Sojae Semen Nigrum (Heidou, 100 grains).
Preparation: Coarsely chop the four ingredients. Soak them in 1 sheng of clear wine in a bowl the day before the expected attack. Cover the bowl with white paper and place a knife horizontally across the top. When the attack is imminent, divide the liquid into three parts. Drink one part first; if no vomiting occurs, drink another part. Vomiting indicates recovery.
For treating Jianri Nue, Beijiyi Yuan San (Emergency Single-Grain Powder):
Prepare ash from burning the tail of a black cow. Take one fangcun bi (approx. 2-3 grams) with wine, three times daily.
For treating the chills and fever of Jianri Nue, Changshan Tang (Crownvetch Root Decoction):
Ingredients: Hedyotisae Herba (Changshan, 0.5 fen), Lophatheri Herba (Zhuye, 0.5 fen, finely chopped), Sorghi Fructus (Shumi, 50 grains; glutinous rice may be used instead), and Gypsum Fibrosum (Shigao, 2 liang, crushed).
Preparation: Coarsely crush and sieve the four ingredients. For each dose, take 5 qianbi, soak in 1.5 zhan of water overnight. Decoct at dawn until 1 zhan remains, strain, and take warm. Take one dose before the onset of symptoms and another just before the attack. On that day, avoid washing or eating/drinking anything other than the remaining medicinal juice, which should be applied to the palms, soles, chest, head, and face. Place the dregs near the pillow.
For treating Jianri Nue, Nuomi Zhu San (Glutinous Rice Boiled Powder):
Ingredients: Oryzae Fructus Glutinosa (Nuomi, 40 grains), Hedyotisae Herba (Changshan, chopped), Pruni Mume Carnis (Wumei Rou, fried), Lophatheri Herba (Zhuye, chopped), Glycyrrhizae Radix et Rhizoma (Gancao, 0.5 liang, honey-fried), and Gypsum Fibrosum (Shigao, 1.5 liang, crushed).
Preparation: Crush and sieve the six ingredients into a powder. For each dose, take 5 qianbi, decoct with 1.5 zhan of water until 0.7 zhan remains, strain, and take warm before the onset of symptoms.
For treating malaria occurring every other day, Dahuang Tang (Rhubarb Decoction):
Ingredients: Rhei Radix et Rhizoma (Dahuang, raw, 0.5 liang), Glycyrrhizae Radix et Rhizoma (Gancao, honey-fried and chopped), Hedyotisae Herba (Changshan, chopped), and Cinnamomi Ramulus (Gui, bark removed, 0.5 fen).
Preparation: Coarsely crush and sieve the four ingredients. For each dose, take 5 qianbi, decoct with 1.5 zhan of water until 0.7 zhan remains, strain, and take warm before the onset of symptoms.
For treating Jianri Nue, Shenwen Wan (Divine Pill):
Ingredients: Sojae Semen Nigrum (Heidou, 21 small beans, soaked in water to remove skins), Realgar (Pishuang, 1 qian, ground), and Ziziphi Jujubae Fructus (Dazao, one date, boiled, peeled, and pitted).
Preparation: These ingredients must be compounded on the Dragon Boat Festival (Duanwu) or Qixi Festival. Grind them together and form pills the size of pea seeds, coating them with Cinnabar (Dansha). Avoid exposure to women, chickens, and dogs during preparation. On the morning of the attack, face north, pass the pill over incense smoke, and swallow with cold tea. Avoid hot food or drink for one shichen (two hours).