论曰骨髓之病，应肝胆，若其腑脏有病，皆从髓生，热则应脏。寒则应腑，故髓虚者、
脑痛不安。身常清栗。髓实者、身体烦躁。勇悍惊热。当随证以治之。
治髓虚寒脑痛不安。补髓羌活丸方
羌活（去芦头） 芎 当归（切炒各一两半） 桂（去粗皮一两） 人参（二两） 大
枣（三
上一十味，捣罗五味为末，与枣肉麻仁酥髓相和。入银瓷器中，重汤煮之，候稠可丸，
即丸如梧桐子大，每服三十丸，空腹温酒下，加至四十丸。
治髓虚寒。地黄煎方
生地黄（五斤洗焙） 补骨脂 人参（各五两）
上三味，捣罗为末，每用酒二升，药末二两，羊髓一具，去筋膜，一处细研，慢火熬稠。
瓷器盛之，每服一小匙，温酒化下，空心日午卧时各一。
治髓虚骨寒。温髓汤方
附子（炮裂去皮脐） 人参 黄 细辛（去苗叶） 桂（去粗皮各一两）
上五味，锉如麻豆，每服三钱匕，水一盏，煎至七分去滓，空心食前温服。
治髓实勇悍，髓热生烦。柴胡汤方
柴胡（去苗） 升麻 黄芩（去黑心） 细辛（去苗叶） 枳实（去瓤麸炒） 栀子仁
（各三分）
上九味，粗捣筛，每服五钱匕，水一盏半，煎至一盏，下芒硝半钱，再煎一沸，去滓分
二服。早食后日中服。
治髓实气勇悍烦热。枳实汤方
枳实（去瓤麸炒） 柴胡（去苗） 当归（切焙） 芎 甘草（微炙锉各一两）
上五味，粗捣筛，每服三钱匕，水一盏，煎至七分，去滓温服，食后夜卧。
治髓实使人强悍惊热。地骨皮汤方
地骨皮（洗二两） 胡黄连 柴胡（去苗） 当归（切焙） 泽泻 黄芩（去黑心） 甘
草（炙
上八味，粗捣筛，每服三钱匕，水一盏，煎至七分，去滓温服，日二夜一。
论述说：骨髓的病变，与肝胆相应。如果脏腑发生疾病，都源于骨髓的变化；热证对应脏，寒证对应腑。因此，髓虚的人会出现脑痛、心神不安；身体经常感到清冷战栗。髓实的人则表现为身体烦躁、勇悍且易受惊、伴有热象。治疗应当根据具体证候来进行。
治疗髓虚寒所致脑痛不安的补髓羌活丸方：
羌活（去除芦头）、川芎、当归（切片炒制，各一两半）、桂枝（去除粗皮，一两）、人参（二两）、大枣（十枚）。
以上十味药（注：原文此处可能有脱漏或排版错误，列出的药材不足十味，但按原文记录），将其中五味捣碎过筛成细末，与枣肉、麻仁、酥油及羊髓混合。放入银质或瓷质容器中，隔水加热煮至稠厚可制成丸剂，即制成如梧桐子大小的丸药。每次服用三十丸，空腹时用温酒送服，剂量可增加至四十丸。
治疗髓虚寒的地黄煎方：
生地黄（五斤，洗净焙干）、补骨脂、人参（各五两）。
以上三味药，捣碎过筛成细末。每次取药末二两，酒二升，一具羊髓（去除筋膜），一起细细研磨，用慢火熬煮至稠厚。装入瓷器中保存。每次服用一小匙，用温酒化开送服，分别在空腹时、中午和睡前服用。
治疗髓虚骨寒的温髓汤方：
附子（炮裂，去皮脐）、人参、黄芪、细辛（去苗叶）、桂枝（去除粗皮，各一两）。
以上五味药，锉碎如麻豆大小。每次服用三钱匕，加水一盏，煎煮至七分，去渣，空腹及食前温服。
治疗髓实、勇悍、髓热生烦的柴胡汤方：
柴胡（去苗）、升麻、黄芩（去除黑心部分）、细辛（去苗叶）、枳实（去瓤麸炒）、栀子仁（各三分）。
以上九味药，粗捣后过筛。每次服用五钱匕，加水一盏半，煎煮至一盏，加入芒硝半钱，再煮沸一次，去渣分两次服用。在早饭后和日中时分服。
治疗髓实气盛、勇悍烦热的枳实汤方：
枳实（去瓤麸炒）、柴胡（去苗）、当归（切片焙干）、川芎、甘草（微炙后锉碎，各一两）。
以上五味药，粗捣后过筛。每次服用三钱匕，加水一盏，煎煮至七分，去渣温服，在食后和夜卧前服用。
治疗髓实使人强悍、易惊发热的地骨皮汤方：
地骨皮（洗净，二两）、胡黄连、柴胡（去苗）、当归（切片焙干）、泽泻、黄芩（去除黑心部分）、甘草（炙制）。
以上八味药，粗捣后过筛。每次服用三钱匕，加水一盏，煎煮至七分，去渣温服，每日两次夜间一次。
It is discussed that diseases of the bone marrow correspond to the Liver and Gallbladder. If there are diseases in the Zang-Fu organs, they all originate from the bone marrow; heat syndromes correspond to the Zang organs, while cold syndromes correspond to the Fu organs. Therefore, those with Bone Marrow Deficiency (Sui Xu) experience headache and mental restlessness, and their bodies often feel cold and tremble. Those with Bone Marrow Excess (Sui Shi) manifest as bodily irritability, courage and ferocity, susceptibility to fright, and heat sensations. Treatment should be based on the specific syndrome.
Formula for Supplementing Marrow Qianghuo Wan (Cnidium Pill) for treating Bone Marrow Deficiency-Cold causing headache and mental restlessness:
Qianghuo (Notopterygii Rhizoma et Radix, remove rhizome head), Chuanxiong (Ligustici Chuanxiong Rhizoma), Danggui (Angelicae Sinensis Radix, sliced and stir-fried, each 1.5 liang), Guizhi (Cinnamomi Ramulus, remove coarse bark, 1 liang), Renshen (Ginseng Radix, 2 liang), Dazao (Jujubae Fructus, 10 pieces).
The above ten ingredients (Note: The original text lists fewer than ten distinct items here, but recorded as per source), pound and sieve five of them into fine powder, and mix with Jujube flesh, Sesami Semen, butter, and sheep marrow. Place in a silver or porcelain vessel, boil over water until thick enough to form pills. Form into pills the size of Sophora japonica seeds. Take 30 pills each time, administered with warm wine on an empty stomach; the dose may be increased to 40 pills.
Di Huang Jian (Rehmannia Decoction Paste) for treating Bone Marrow Deficiency-Cold:
Sheng Dihuang (Rehmanniae Radix Recens, 5 jin, washed and dried), Buguzhi (Psoraleae Fructus), Renshen (Ginseng Radix, each 5 liang).
Pound and sieve the above three ingredients into fine powder. For each use, take 2 liang of medicine powder, 2 sheng of wine, and one whole sheep marrow (remove fascia). Grind finely together and simmer slowly over low heat until thick. Store in a porcelain container. Take one small spoon each time, dissolved in warm wine. Administer on an empty stomach, at noon, and before sleep.
Wen Sui Tang (Warm Marrow Decoction) for treating Bone Marrow Deficiency and Bone Cold:
Fuzi (Aconiti Lateralis Radix Praeparata, roasted until cracked, remove skin and umbilicus), Renshen (Ginseng Radix), Huangqi (Astragali Radix), Xixin (Asari Radix et Rhizoma, remove seedlings and leaves), Guizhi (Cinnamomi Ramulus, remove coarse bark, each 1 liang).
Cinch the above five ingredients like hemp beans. Take three qianbi each time, add one zhan of water, decoct until reduced to seven-tenths, remove dregs, and take warm on an empty stomach and before meals.
Chaihu Tang (Bupleurum Decoction) for treating Bone Marrow Excess with courage/ferocity, marrow heat generating irritability:
Chaihu (Bupleuri Radix, remove seedlings), Shengma (Cimicifugae Rhizoma), Huangqin (Scutellariae Radix, remove black heart), Xixin (Asari Radix et Rhizoma, remove seedlings and leaves), Zhishi (Aurantii Fructus Immaturus, remove pulp and bran, stir-fried), Zhizi Ren (Gardeniae Semen, each 3 fen).
Coarsely crush and sieve the above nine ingredients. Take five qianbi each time, add one and a half zhan of water, decoct until reduced to one zhan. Add Mangxiao (Natrii Sulfas, half qian), boil once more, remove dregs, and divide into two doses. Take after morning meal and at midday.
Zhishi Tang (Aurantii Fructus Immaturus Decoction) for treating Bone Marrow Excess with qi excess, courage/ferocity, and irritability-heat:
Zhishi (Aurantii Fructus Immaturus, remove pulp and bran, stir-fried), Chaihu (Bupleuri Radix, remove seedlings), Danggui (Angelicae Sinensis Radix, sliced and dried), Chuanxiong (Ligustici Chuanxiong Rhizoma), Gancao (Glycyrrhizae Radix et Rhizoma, lightly roasted and cut, each 1 liang).
Coarsely crush and sieve the above five ingredients. Take three qianbi each time, add one zhan of water, decoct until reduced to seven-tenths, remove dregs, and take warm. Administer after meals and before night sleep.
Digupi Tang (Dighan Cortex Decoction) for treating Bone Marrow Excess causing courage/ferocity and fright-heat:
Digupi (Phellodendri Cortex, washed, 2 liang), Huhuanglian (Coptidis Rhizoma - *Note: Original says Hu Huanglian, likely referring to Coptis or similar bitter-cold herb, usually Coptidis Rhizoma is Huanglian, Hu Huanglian might be a typo or specific variety, keeping literal translation*), Chaihu (Bupleuri Radix, remove seedlings), Danggui (Angelicae Sinensis Radix, sliced and dried), Zexie (Alismatis Rhizoma), Huangqin (Scutellariae Radix, remove black heart), Gancao (Glycyrrhizae Radix et Rhizoma, roasted).
Coarsely crush and sieve the above eight ingredients. Take three qianbi each time, add one zhan of water, decoct until reduced to seven-tenths, remove dregs, and take warm. Take twice daily and once at night.