蛇蜕（畏磁石及酒）
蜣螂（畏羊角、石膏）
斑蝥（马刀为使，畏巴豆、丹参、空青，恶肤青）
地胆（恶甘草）
马刀（得水良）
大枣（杀乌头毒）
杏仁（得火良，恶黄 、黄芩、葛根，解锡、胡粉毒，畏莽草）
冬葵子（黄芩为使）
葱实（解藜芦毒）
麻 、麻子（畏牡蛎、白薇，恶茯苓）
大豆及黄卷（恶五参、龙胆，得前胡、乌喙、杏仁、牡蛎良，杀乌头毒）
大麦（食蜜为使）
酱（杀药毒、火毒）。
上一百九十七种有相制使，其余皆无，故不备录。
或曰∶古人用药至少，分两亦轻，瘥病极多；观君处方，非不烦重，分两亦多，而瘥病
不及古人者，何也？答曰∶古者日月长远，药在土中，自养经久，气味真实，百姓少欲，禀
气中和，感病轻微，易为医疗。今时日月短促，药力轻虚，人多巧诈，感病浓重，难以为医。
病轻用药须少， 重用药即多。此则医之一隅，何足怪也。又古之医者，自将采取，阴干、
曝干，皆悉如法，用药必根据土地，所以治十得九。今之医者，但知诊脉处方，不委采药时节。
至于出处土地，新陈虚实，皆不悉，所以治十不得五六者，实由于此。夫处方者，常须加意，
重复用药，药乃有力。若学古人，徒自误耳。将来学人，须详熟之。
凡紫石英、白石英、朱砂、雄黄、硫黄等，皆须光明映澈，色理鲜净者为佳。不然令人
身体干燥，发热口干而死。
凡草石药，皆须土地坚实，气味浓烈，不尔，治病不愈。
凡野狼毒、枳实、橘皮、半夏、麻黄、吴茱萸，皆欲得陈久者良，其余唯须精新也。
蛇蜕（畏惧磁石和酒）
蜣螂（畏惧羊角、石膏）
斑蝥（以马刀为使药，畏惧巴豆、丹参、空青，厌恶肤青）
地胆（厌恶甘草）
马刀（遇水则药效良好）
大枣（能消除乌头的毒性）
杏仁（遇火则药效良好，厌恶黄[此处原文缺字，通常指黄柏或黄连，依古籍惯例暂留]、黄芩、葛根，能解除锡毒和胡粉毒，畏惧莽草）
冬葵子（以黄芩为使药）
葱实（能解除藜芦的毒性）
麻[此处原文缺字，结合下文“麻子”及中药常识，通常指大麻叶或麻黄茎皮类，但后文有麻黄，此处疑为麻黄之茎或大麻仁等，依原文保留]、麻子（畏惧牡蛎、白薇，厌恶茯苓）
大豆及其发芽品黄卷（厌恶五参、龙胆，与前胡、乌喙、杏仁、牡蛎同用则效果良好，能消除乌头毒性）
大麦（以食蜜为使药）
酱（能消除药物毒性和火毒）。
以上一百九十七种药材存在相制使关系，其余都没有，所以不再全部记录。
有人问：古人用药剂量很少，分量也很轻，治愈的疾病却极多；看您的处方，并非不繁琐沉重，分量也很多，而治愈疾病不如古人的原因，是什么呢？回答说：古代日月长久，药材在土壤中自然生长时间久，气味真实纯正，百姓欲望少，禀受的中正之气平和，感受的病邪轻微，容易治疗。现在时局短促，药力轻浮虚弱，人多巧诈，感受的病邪浓重，难以医治。病轻时用药须少，病重时用药即多。这只是医学的一个方面，有什么值得奇怪的呢？另外古代的医生，亲自采集药材，阴干、曝干，都完全符合法度，用药必定依据产地土地的特性，所以治疗十个能治好九个。现在的医生，只知道诊脉开方，不了解采药的时节。至于药材的出处土地、新旧虚实，都不完全了解，所以治疗十个治不好五六，确实是由于这个原因。开具处方的人，常常需要用心，重复斟酌用药，药力才能发挥效力。如果盲目学习古人，只会误导自己罢了。后来的学习者，必须详细熟记这些内容。
凡是紫石英、白石英、朱砂、雄黄、硫黄等，都必须光明透彻，色泽纹理新鲜洁净的才好。不然会让人身体干燥，发热口干而死。
凡是草木药材，都必须产地土壤坚实，气味浓烈，不这样的话，治病不能痊愈。
凡是野狼毒、枳实、橘皮、半夏、麻黄、吴茱萸，都想要得到陈久的为好，其余的只要精细新鲜即可。
She Tui (Ophichan Skin) [dreads Ci Shi (Magnetite) and Jiu (Alcohol)]
Qiang Lang (Scarabaeus) [dreads Yang Jiao (Ram's Horn) and Shi Gao (Gypsum Fibrosum)]
Ban Mao (Mylabris) [uses Ma Dao (Lithospermum Erythrorhizon? Note: Context suggests a specific herb, likely 马兜铃 or similar, but literal is Horse Knife/Clam. In pharmacology context, often refers to a specific mineral or herb acting as guide. WHO term may vary. Here translated literally as Ma Dao] as the guiding drug; dreads Ba Dou (Crotonis Fructus), Dan Shen (Salviae Miltiorrhizae Radix et Rhizoma), Kong Qing (Azurite); detests Fu Qing (Malachite)]
Di Dan (Euphorbiae Humifusae Herba) [detastes Gan Cao (Glycyrrhizae Radix et Rhizoma)]
Ma Dao [performs well when combined with water]
Da Zao (Jujubae Fructus) [kills Wu Tou (Aconiti Radix) toxicity]
Xing Ren (Armeniacae Semen Amarum) [performs well when heated; detastes Huang [missing character, likely Huang Bo/Lian Lian], Huang Qin (Scutellariae Radix), Ge Gen (Puerariae Lobatae Radix); resolves Xi (Tin) and Hu Fen (Lead Carbonate) toxicity; dreads Mang Cao (Isatidis Folium? Or specific toxic herb)]
Dong Kui Zi (Abutili Semen) [uses Huang Qin (Scutellariae Radix) as the guiding drug]
Cong Shi (Allii Fistulosi Bulbus) [resolves Li Lu (Veratri Nigrum Radix) toxicity]
Ma [missing character, likely Da Ma or part of Mahuang] , Ma Zi (Cannabis Fructus) [dreads Mu Li (Ostreae Concha), Bai Wei (Cynanchi Atrati Radix); detastes Fu Ling (Poria)]
Da Dou (Sojae Semen Glanduliferum) and Huang Juan (Sojae Germinatum) [detastes Wu Shen (Five Ginsengs), Long Dan (Gentianae Radix); performs well with Qian Hu (Peucedani Radix), Wu Hui (Aconiti Radix Preparata), Xing Ren (Armeniacae Semen Amarum), Mu Li (Ostreae Concha); kills Wu Tou (Aconiti Radix) toxicity]
Da Mai (Hordei Fructus Germinatus) [uses Shi Mi (Mel) as the guiding drug]
Jiang (Fermented Soybean Paste) [kills Yao Du (Drug Toxicity) and Huo Du (Fire Toxicity)].
Among the aforementioned one hundred and ninety-seven types, there are mutual restrictions and guiding relationships; the rest have none, so they are not recorded in full.
Someone asked: "Ancients used minimal amounts of medicine, with light dosages, yet cured many diseases; observing your prescriptions, they are not without complexity and heaviness, and dosages are large, yet the cure rate does not match the ancients. Why?" The answer was: "In ancient times, the days were long, medicines remained in the soil for extended periods, nurturing themselves naturally, resulting in authentic and potent flavors. The people had few desires and possessed balanced constitution, contracting mild illnesses that were easy to treat. Today, the era is short, medicinal potency is light and deficient, people are cunning and deceitful, contracting severe illnesses that are difficult to treat. For mild illnesses, less medication is required; for severe illnesses, more medication is needed. This is merely one aspect of medicine, what is there to wonder at? Furthermore, ancient physicians harvested the herbs themselves, drying them in shade or sun according to proper methods, and selected medicines based on their geographical origin. Thus, ten out of ten cases were cured. Modern physicians only know pulse diagnosis and prescription writing, neglecting the timing of herb collection. They are unaware of the origin, soil conditions, freshness, age, and tonifying/purgative properties of the herbs. Therefore, treating ten cases and curing fewer than five is truly due to this. Those who prescribe must pay close attention and repeatedly deliberate on the medications to ensure efficacy. Blindly imitating the ancients will only lead to self-deception. Future students must study these points carefully."
For all Shi Ying (Fluorite), Zhu Sha (Cinnabar), Xiong Huang (Realgar), Liu Huang (Sulfur), etc., they must be bright, clear, fresh in color, and pure in texture to be considered good. Otherwise, they cause dryness of the body, fever, dry mouth, and death.
For all herbal and mineral drugs, the land of origin must be solid, and the flavor and qi must be strong; otherwise, the disease will not be cured.
For Ye Lang Du (Stellerae Radix), Zhi Shi (Aurantii Fructus Immaturus), Ju Pi (Citri Reticulatae Pericarpium), Ban Xia (Pinelliae Rhizoma), Ma Huang (Ephedrae Herba), Wu Zhu Yu (Evodiae Fructus), aged ones are preferred; for the rest, only fine and fresh ones are required.