病源小便难者，此是肾与膀胱热故也，此二经为表里，俱主水，水行于小肠，入胞为小
便，热气在于脏腑，水气则涩，其热势微，故但小便难也，诊其尺脉浮，小便难，尺脉濡，
小便难，尺脉缓，故小便难有余涩也。（出第十四卷中）
集验疗小便难淋沥汤方。
滑石（八两） 石苇（三两去毛） 榆皮（一升） 葵子（一升） 通草（四两）
上五味切，以水一斗，煮取三升，分三服，一方加黄芩三两。
又疗淋小便不利，阴痛，石苇散方
石苇（二两去毛） 瞿麦（一两） 滑石（五两） 车前子（三两） 葵子（二两）
上五味捣筛为散，服方寸匕，日三。（并出第五卷中）
千金疗小便不利，茎中痛，少腹急方。
通草（二两） 葶苈子（熬三两） 茯苓（二两）
上三味捣为散，以水服方寸匕，日三服。忌醋物。（出第二十一卷中）
备急疗小便不利，茎中痛剧，亦疗妇人血结腹坚痛，牛膝饮方。
生牛膝一名牛唇，掘取根煮服之，立瘥。（肘后同）
陶效方。
秦艽（二分） 冬瓜子（二两）
上二味捣为末，酒服一匕，日三服，神良。（肘后同）
文仲疗小便不利方。
桑螵蛸（三十枚） 黄芩（一两）
上二味切，以水一升，煮取四合，顿服之良。（肘后同）
又方
蒲黄 滑石（各一分）
上二味为散，酒服一匕，日三，大验。（肘后同）
又疗诸淋及小便常不利，阴中痛，日数十度起，此皆劳损虚热所致，常将散服方。
石苇（去毛） 滑石 瞿麦 王不留行 葵子（各二两）
上六味捣筛为散，每服方寸匕，日三服之，姚方加滑石五两，车前子三两，无王不留行
。（备急同出第四卷中）
古今录验疗淋胞痛，不得小便滑石散方。
滑石 葵子 钟乳（各一两） 桂心 通草 王不留行（各半两）
上六味捣筛为散，先食讫，以酒服方寸匕，日三服。忌生葱。（出第二十六卷中）
病因方面，小便困难，是因为肾与膀胱有热所致。这两条经脉互为表里，都主管水液代谢。水液运行于小肠，进入膀胱后形成小便。当热气存在于脏腑中时，水液的运行就会变得涩滞不畅。如果热势轻微，就仅仅表现为小便困难。诊察时，若尺部脉象浮，主小便困难；尺部脉象濡软，主小便困难；尺部脉象缓，则说明小便困难伴有其他涩滞症状。（出自第十四卷）
集验方治疗小便困难、淋漓不尽的汤剂。
滑石（八两） 石苇（三两，去毛） 榆皮（一升） 葵子（一升） 通草（四两）
以上五味药切碎，用水一斗，煎煮至三升，分三次服用。另一版本加黄芩三两。
又方治疗淋证、小便不利、阴部疼痛的石苇散方。
石苇（二两，去毛） 瞿麦（一两） 滑石（五两） 车前子（三两） 葵子（二两）
以上五味药捣碎过筛制成散剂，每次服用一方寸匕，每日三次。（均出自第五卷）
千金方治疗小便不利、尿道疼痛、少腹部拘急的方剂。
通草（二两） 葶苈子（炒制三两） 茯苓（二两）
以上三味药捣碎制成散剂，用水送服一方寸匕，每日三次。忌食醋类食物。（出自第二十一卷）
备急方治疗小便不利、尿道剧痛，也治疗妇人血结导致腹部坚硬疼痛的牛膝饮方。
生牛膝又名牛唇，挖掘其根部煮水服用，立即痊愈。（与《肘后方》相同）
陶隐居效方。
秦艽（二分） 冬瓜子（二两）
以上两味药捣碎成末，用酒送服一方寸匕，每日三次，效果极佳。（与《肘后方》相同）
文仲治疗小便不利的方剂。
桑螵蛸（三十枚） 黄芩（一两）
以上两味药切碎，用水一升，煎煮至四合，一次性服用效果良好。（与《肘后方》相同）
又一方
蒲黄 滑石（各一分）
以上两味药制成散剂，用酒送服一方寸匕，每日三次，疗效显著。（与《肘后方》相同）
又方治疗各种淋证及小便经常不利，阴中疼痛，每天发作数十次起床排尿，这都是因劳损虚热所致，常备散剂服用方。
石苇（去毛） 滑石 瞿麦 王不留行 葵子（各二两）
以上六味药捣碎过筛制成散剂，每次服用一方寸匕，每日三次服用。姚氏方加滑石五两，车前子三两，无王不留行。（与《备急方》同出第四卷）
古今录验方治疗淋证、膀胱疼痛、无法排尿的滑石散方。
滑石 葵子 钟乳（各一两） 桂心 通草 王不留行（各半两）
以上六味药捣碎过筛制成散剂，饭后，用酒送服一方寸匕，每日三次。忌食生葱。（出自第二十六卷）
Etiologically, difficulty in urination is caused by heat in the Kidney and Bladder. These two meridians are exterior-interiorly related and both govern water metabolism. Water flows through the Small Intestine, enters the Bladder (Pao), and becomes urine. When pathogenic heat resides within the Zang-Fu organs, the flow of water becomes obstructed and astringent. If the heat intensity is mild, it manifests merely as difficulty in urination. Upon pulse diagnosis, if the Chi position pulse is Floating (Fu), it indicates difficulty in urination; if the Chi position pulse is Soft (Ru), it indicates difficulty in urination; if the Chi position pulse is Slow (Huan), it suggests that difficulty in urination is accompanied by other signs of obstruction and astringency. (From Volume XIV)
Jiyan Formula for Decoction to Treat Difficulty in Urination and Dribbling.
Talcum (8 liang) Shiwei Folium (3 liang, remove hairs) Ulmus Pterysea Cortex (1 sheng) Malvae Semen (1 sheng) Trogopterori Mass (4 liang) [Note: Tongcao refers to Tetrapanacis Medulla]
The above five herbs are cut into pieces, boiled in 10 dou of water until reduced to 3 sheng, and divided into three doses. Another version adds Huangqin Radix (3 liang).
Another formula, Shiwei Powder, to treat Lin Syndrome, difficulty in urination, and pain in the yin region.
Shiwei Folium (2 liang, remove hairs) Dianthi Herba (1 liang) Talcum (5 liang) Plantaginis Semen (3 liang) Malvae Semen (2 liang)
The above five herbs are pounded and sifted into a powder. Take one Fangcunbi (a square-inch measure) per dose, three times daily. (Both from Volume V)
Qianjin Formula to Treat Difficulty in Urination, Pain in the Urethra, and Tightness in the Lower Abdomen.
Trogopterori Mass (2 liang) [Note: Tongcao refers to Tetrapanacis Medulla] Lepidii Semen (roasted, 3 liang) Poria (2 liang)
The above three herbs are pounded into a powder. Take one Fangcunbi with water, three times daily. Avoid vinegar and acidic foods. (From Volume XXI)
Biji Formula for Niuxi Drink to Treat Difficulty in Urination, Severe Pain in the Urethra, and also to treat women with blood stagnation causing hardness and pain in the abdomen.
Fresh Achyranthis Bidentatae Radix (also known as Niuchun). Dig up the roots, decoct, and take. Recovery is immediate. (Same as in Zhouhou Fang)
Tao Hongjing’s Effective Formula.
Gardenia Ginseng (Qinjiao Radix et Rhizoma) (2 fen) Benincasae Semen (2 liang)
The above two herbs are pounded into fine powder. Take one bi with wine, three times daily. Highly effective. (Same as in Zhouhou Fang)
Wenzhong’s Formula to Treat Difficulty in Urination.
Mantis Ootheca (Sangpiaoxiao) (30 pieces) Scutellariae Radix (Huangqin) (1 liang)
The above two herbs are cut into pieces, decocted in 1 sheng of water until reduced to 4 ge, and taken in one dose. Effective. (Same as in Zhouhou Fang)
Another Formula
Coptidis Rhizoma (Puhuang) [Note: Puhuang is Typhae Pollen] Talcum (Each 1 fen)
The above two herbs are made into a powder. Take one bi with wine, three times daily. Very effective. (Same as in Zhouhou Fang)
Another formula to treat various Lin Syndromes and chronic difficulty in urination, pain in the yin, frequent urination many times a day. These are all caused by exhaustion-induced deficiency-heat. This is a commonly kept powder formula.
Shiwei Folium (remove hairs) Talcum Dianthi Herba Galla Chinensis [Note: Wangbuliuxing is Vaccariae Semen] Malvae Semen (Each 2 liang)
The above six herbs are pounded and sifted into a powder. Take one Fangcunbi per dose, three times daily. Yao’s formula adds Talcum (5 liang) and Plantaginis Semen (3 liang), without Vaccariae Semen. (Same as Biji Fang, from Volume IV)
Gujin Luyan Formula for Shihui Powder to treat Lin Syndrome, Bladder Pain, and Inability to Urinate.
Talcum Malvae Semen Gypsum Fibrosum (Zhongru) (Each 1 liang) Cinnamomi Ramulus (Guixin) Trogopterori Mass [Note: Tongcao refers to Tetrapanacis Medulla] Vaccariae Semen (Each 0.5 liang)
The above six herbs are pounded and sifted into a powder. After meals, take one Fangcunbi with wine, three times daily. Avoid raw green onions. (From Volume XXVI)