许仁则云，此病有两种一名干霍，一名湿霍，干霍死者多，湿霍死者少，俱繇饮食不节
，将息失宜，干霍之状，。心腹胀满，搅刺疼痛，烦闷不可忍，手足逆冷甚者流汗如水，大
小便不通，求吐不出，求痢不下，须臾不救，便有性命之虑，湿霍之状，心腹亦搅痛，诸候
有与干同，但吐痢无限，此病始得，有与天行相似者，亦令头痛，骨肉酸楚，手足逆冷，四
体发热，干霍大小便不通，烦冤欲死，宜急与巴豆等三味丸服之，服取快利方。
巴豆（一百枚熬去心皮） 干姜（三两崔氏以芒硝五两代与千金同） 大黄（五两）
右药先捣干姜大黄为散，后别捣巴豆如膏，和前二味同捣令调，细细下蜜丸，以饮下，
初服三丸，如梧子大，服讫，数 肚，令转动速下利，良久不觉，则以热饮投之，又良久不
利，更服一丸，须臾当利，利后好将息食饮寒温。以意取适，如渴者煮浆水粥少少啜之。忌
野猪肉芦笋等物。（张文仲处）
又疗湿霍乱吐痢无限，宜合高良姜等三味饮子服之方
高良姜（二两） 豆蔻子（十二枚） 桂心（二两）
右药切，以水四升，煮取一升，去滓，细细啜之，亦有于此方加干姜人参二物。忌生葱
又木瓜桂心二物饮之方。
木瓜（一枝湿干并得） 桂心（二两）
右药以水二升，煮取七合，去滓，细细饮之，亦有豆蔻子代桂心者，亦有单煮，木瓜汁
饮之。忌生葱。（吴升同出第一卷中）
许仁则说，这种病有两种名称：一名干霍乱，一名湿霍乱。患干霍乱死亡的人多，患湿霍乱死亡的人少，这都是由于饮食不节制，调养失当所致。
干霍乱的证状是：心腹胀满，腹部绞痛刺痛，烦闷得难以忍受，手足逆冷，严重的甚至出汗如水，大小便不通畅，想吐却吐不出来，想泻却泻不下来，如果片刻不及时救治，就会有生命危险。
湿霍乱的证状是：心腹也发生绞痛，各种症状有的与干霍乱相同，只是呕吐和腹泻无限制地发生。这种病刚发作时，有的与“天行”（流行性传染病）相似，也会引起头痛，骨节肌肉酸痛，手足逆冷，四肢发热。
对于干霍乱导致的大小便不通，烦冤欲死的情况，应当立即给予巴豆等三味药制成的丸剂服用，服药后以迅速通利大便为度。
药物组成：巴豆（一百枚，熬制后去掉心和皮）、干姜（三两，崔氏用芒硝五两代替，千金方与此相同）、大黄（五两）。
以上药物先捣碎干姜和大黄成为散剂，然后另外捣碎巴豆成膏状，与前两种药末混合捣匀，慢慢加入蜂蜜制成丸剂，用温水送服。初次服用三丸，如梧桐子大小。服完后，揉按腹部，使气机转动，促使快速下利。过了很久仍感觉不到效果，就用热饮冲服；又过了很久仍然不利，再服一丸，片刻之后应当能通利。通利之后，要好好调养饮食，注意寒温适宜，凭心意选择舒适的食物。如果口渴，可以煮浆水粥少量饮用。忌食野猪肉、芦笋等食物。（出自张文仲处）
又一种治疗湿霍乱呕吐腹泻无限制的方子，宜配制高良姜等三味药组成的饮子服用。
以上药物切碎，用水四升，煮取一升，去渣，细细啜饮。也有在这个方中加入干姜、人参两味药的。忌食生葱。
以上药物用水二升，煮取七合，去渣，细细饮服。也有用豆蔻子代替桂心的，也有单煮木瓜取汁饮用的。忌食生葱。（吴升同出第一卷中）
Xu Renze stated that this disease has two names: one is Gan Huoluan (Dry Cholera), and the other is Shi Huoluan (Wet Cholera). More patients die from Gan Huoluan, while fewer die from Shi Huoluan. Both are caused by irregular diet and improper nursing.
The symptoms of Gan Huoluan include abdominal distension and fullness, twisting and stabbing pain in the abdomen, unbearable restlessness and oppression, cold extremities, and in severe cases, profuse sweating like water. There is obstruction of both urination and defecation; the patient desires to vomit but cannot, and desires to have diarrhea but cannot. If not rescued promptly, it poses a threat to life.
The symptoms of Shi Huoluan also include twisting pain in the heart and abdomen. Some manifestations are similar to those of Gan Huoluan, but vomiting and diarrhea occur incessantly. At the onset, this disease may resemble Tianxing (Epidemic Disease), accompanied by headache, soreness and pain of bones and muscles, cold extremities, and heat in the four limbs.
For Gan Huoluan characterized by obstruction of urination and defecation, extreme restlessness, and a desire to die, one should urgently administer pills made from Radix Crotonis Fructus (Badou) and two other ingredients. The medication should be taken until rapid purgation is achieved.
Ingredients: Radix Crotonis Fructus (Badou, 100 seeds, roasted, hearts and skins removed); Rhizoma Zingiberis Preparatum (Ganjiang, 3 liang; Cui's formula uses Natrii Sulfas/Mangxiao 5 liang instead; Qianjin Fang is the same); Radix et Rhizoma Rhei (Dahuang, 5 liang).
First, pound the Ganjiang and Dahuang into a powder. Then, separately pound the Badou into a paste. Mix the paste with the two powders thoroughly. Gradually add honey to form pills. Administer with warm water. Initially, take three pills, sized like Sophora japonica seeds (Wutongzi). After ingestion, massage the abdomen to promote qi movement and induce rapid diarrhea. If no effect is felt after a long time, administer hot drinks. If still no effect after another period, take one more pill; diarrhea should occur shortly thereafter. After purgation, carefully regulate diet and beverage temperature according to one's comfort. If thirsty, drink small amounts of cooked Jiangshui Zhou (fermented rice gruel). Avoid wild boar meat, Asparagus cochinchinensis (Lusun), and other such foods. (From Zhang Wenzhong's collection)
Another prescription for treating Shi Huoluan with incessant vomiting and diarrhea involves a decoction of Gao Liangjiang and two other ingredients.
Ingredients: Rhizoma Alpiniae Officinarum (Gaoliangjiang, 2 liang); Semen Cardamomi Rotundae (Doukouzi, 12 seeds); Cortex Cinnamomi (Guixin, 2 liang).
Chop the herbs, boil in 4 sheng of water until reduced to 1 sheng, strain, and sip slowly. Some variations add Rhizoma Zingiberis Recens (Ganjiang) and Radix Ginseng (Renshen). Avoid raw green onions.
Another prescription consists of a decoction of Fructus Chaenomelis (Mugua) and Cortex Cinnamomi (Guixin).
Ingredients: Fructus Chaenomelis (Mugua, one branch, fresh or dried); Cortex Cinnamomi (Guixin, 2 liang).
Boil in 2 sheng of water until reduced to 7 he, strain, and drink slowly. Some versions substitute Semen Cardamomi Rotundae (Doukouzi) for Cortex Cinnamomi (Guixin), or simply boil Fructus Chaenomelis (Mugua) alone to extract the juice for drinking. Avoid raw green onions. (Also found in Volume I, attributed to Wu Sheng)