病源霍乱者由人温凉不调，阴阳清浊二气，有相干乱之时其乱在于肠胃之间者，因遇饮
食而变，发则心腹绞痛，其有先心痛者则先吐，先腹痛者则先痢，心腹并痛者，则吐痢俱发，
挟风而实者，身发热，头痛体疼而复吐痢，虚者但吐痢心腹刺痛而已，亦有饮酒食肉好餐腥
脍，生冷过度，或居处不节，或露卧湿地，或当风取凉，而风冷之气归于三焦，传于脾胃，
脾胃得冷则不磨，不磨则水谷不消化，亦令清浊二气相干，脾胃虚弱，便生吐痢，水谷不消
则令心腹胀满，皆成霍乱，霍乱有三名，一名胃反，言其胃气虚逆，反吐饮食也，二名霍
乱，言其病挥霍之间，便致撩乱也，三名走哺，言其哺食变逆者也，诊其脉来代者霍乱，又
脉代而绝者亦霍乱，霍乱脉大可疗，微细不可疗，霍乱吐下，脉微迟，气息劣，口不欲言者，
不可疗也，养生方云，七月食蜜，令人暴下发霍乱。（出第二十二卷中）
千金论曰∶原夫霍乱之为病也，皆因食饮，非关鬼神，饱食肫脍，复餐乳酪，海陆百品
无所不啖，眠卧冷席，多饮寒浆，胃中诸食，结而不消，阴阳二气，拥而反戾，阳气欲降，
阴气欲升，阴阳乖隔，变成吐痢，头痛如破，百节如解，遍体诸筋，皆为回转，论证虽小卒
病之中，最为可畏，虽临深履危不足以喻之也，养生者宜达其旨趣庶可免于天横者矣。又凡
霍乱务在温和将息，若冷则遍体转筋，凡此病定已后，一日不食为佳，仍须三日少少吃粥，
三日以后，乃可恣意食息也，七日勿杂食为佳，所以养脾气也。（出第二十卷中）
霍乱的病源，是由于人体对冷暖调节不当，导致阴气与阳气、清气与浊气相互干扰混乱。这种混乱发生在肠胃之间时，往往因饮食而诱发。发病时会出现心腹剧烈绞痛。如果先出现心痛，就会先呕吐；如果先出现腹痛，就会先腹泻；如果心腹同时疼痛，则呕吐和腹泻会同时发生。若兼夹风邪且体质实盛，会出现身体发热、头痛、全身疼痛，并伴有呕吐和腹泻；若体质虚弱，则仅表现为呕吐和腹泻以及心腹刺痛。此外，也有因为饮酒吃肉、喜好生食鱼脍、生冷食物摄入过多，或者居住起居不规律，或露天睡在潮湿之地，或在风口乘凉，导致风寒之气侵入三焦，传导至脾胃。脾胃受寒则无法腐熟运化食物，食物不消化，也会导致清浊二气相互干扰。脾胃虚弱，便产生呕吐和腹泻；水谷不消化，会导致心腹胀满，这些都形成霍乱。
霍乱有三个名称：一名“胃反”，是指胃气虚弱逆乱，反而吐出饮食；二名“霍乱”，是指病情发作迅速（挥霍之间），导致局势混乱；三名“走哺”，是指进食后食物变逆而上。诊察脉象，若脉来有歇止（代脉）的是霍乱；若脉象代且微弱欲绝的也是霍乱。霍乱患者若脉象大者尚可治疗，脉象微细者难治。霍乱吐泻之后，若脉象微迟，气息微弱，口中不想说话，则属不可治疗的危候。养生方记载：七月食用蜂蜜，会让人突然发作霍乱。（出自第二十二卷）
《千金方》论述说：大凡霍乱这种病，都是由于饮食引起，与鬼神无关。如饱食肉酱，又进食乳酪，海陆各种食物无所不吃，睡卧冷席，多喝冷饮，导致胃中各种食物凝结而不消化，阴阳二气壅滞而逆乱。阳气欲降，阴气欲升，阴阳乖隔，从而变成呕吐和腹泻。症状包括头痛如裂，全身关节松弛无力，遍体筋脉痉挛扭转。虽然这只是突发小病之一，但最为可怕，即使形容为面临深渊、脚踏薄冰也不足以比喻其危险。养生之人应当通达其中的旨趣，或许可以避免横死。另外，凡是霍乱患者务必注意温和调养，若受冷则会导致全身转筋。此病痊愈后，第一天不吃东西为佳，随后三天仍需少量喝粥，三天以后，才可以随意饮食休息。七天内不要混杂其他食物为佳，这是为了养护脾气。（出自第二十卷）
The etiology of Huoluan (Colic with Vomiting and Diarrhea) lies in the improper regulation of warmth and coolness by the human body, leading to a time when Yin and Yang, as well as Clear and Turbid Qi, interfere with and disrupt each other. When this disruption occurs between the stomach and intestines, it is triggered by diet. Upon onset, there is severe cramping pain in the heart and abdomen. If heart pain precedes, vomiting occurs first; if abdominal pain precedes, diarrhea occurs first; if both heart and abdomen hurt simultaneously, vomiting and diarrhea occur together. If accompanied by Wind pathogen and characterized by excess syndrome, there is fever, headache, body ache, along with vomiting and diarrhea; if characterized by deficiency syndrome, there is only vomiting, diarrhea, and stabbing pain in the heart and abdomen. Furthermore, some cases arise from drinking alcohol, eating meat, preferring raw fish slices, excessive consumption of cold and raw foods, irregular living habits, sleeping exposed on damp ground, or cooling off in the wind, causing Wind-Cold Qi to enter the Sanjiao (Triple Burner) and transmit to the Spleen and Stomach. The Spleen and Stomach, having received Cold, fail to rot and ripen food; undigested food leads to interference between Clear and Turbid Qi. Spleen and Stomach deficiency generates vomiting and diarrhea; undigested water and grain cause distension and fullness in the heart and abdomen, all constituting Huoluan.
Huoluan has three names: one is "Weifan" (Stomach Reversal), referring to deficient and rebellious Stomach Qi that reverses to vomit food and drink; two is "Huoluan," referring to the disease causing chaos suddenly (in a moment of frivolity); three is "Zoubu," referring to food becoming reversed after ingestion. Diagnosing the pulse, if the pulse comes with intermittent pauses (Dai Mai), it is Huoluan; if the pulse is Dai and faint/almost absent, it is also Huoluan. In Huoluan, a large pulse indicates treatability, while a micro-fine pulse indicates untreatability. After vomiting and purging in Huoluan, if the pulse is micro-slow, breath is weak, and the mouth does not desire speech, it is untreatable. Health preservation formulas state: consuming honey in the seventh month causes sudden onset of Huoluan. (From Volume 22)
The Qianjin Lun states: Originally, Huoluan as a disease is caused by food and drink, not related to ghosts or spirits. One may eat full meals of meat paste, consume milk and cheese, devour hundreds of marine and terrestrial delicacies, sleep on cold mats, and drink heavily of cold liquids. Various foods in the Stomach knot and do not digest; Yin and Yang Qi become congested and rebellious. Yang Qi desires to descend, Yin Qi desires to ascend; Yin and Yang are separated and discordant, transforming into vomiting and diarrhea. Symptoms include headache as if splitting, joints feeling as if dislocated, and all tendons throughout the body twisting and turning. Although this is merely among sudden minor illnesses, it is the most fearful; describing it as facing a deep abyss or treading on thin ice is insufficient to喻 (illustrate) its danger. Those who practice health preservation should understand its purport to avoid premature death. Furthermore, for any Huoluan, one must strive for warm and gentle recuperation; if cold, it causes general body tendon spasms. After this illness has settled, it is best not to eat for one day; thereafter, for three days, one should eat very little congee. After three days, one may then freely eat and rest. It is best not to mix other foods for seven days, so as to nourish Spleen Qi. (From Volume 20)