歌曰∶诸家药线不相同，吾门药线有奇功，虽然砒矾一样用，火候之中看雌雄，不论痰核并 骨，化腐干脓显神通。
（处方） 白砒（三钱） 明矾（七钱）
（制法） 上各研细末，先于锅中滴麻油几滴，次将砒末放入，再将明矾末盖于面上，将锅在武火上烧之，俟砒、
矾干结成饼，烟将尽未尽时，取出研末，以面糊做成细条（如粗丝线）备用。经此制炼之后，砒性已纯，凡瘰 成 ，
及痈疽之久不干脓等，皆可用之。
外科大成之痔漏退管药线方中，有一方亦仅砒、矾二味，只制炼方法微有不同，亦摘录于此，以示此方作用之广∶
白砒五钱，明矾一两五钱，将白砒入铁锅内铺匀，上盖明矾末，以火 之，至矾枯时，喷冷水一口于砒上，随
以棉纸盖于砒上，再随喷水三、五口于纸上，从锅盖边纸上看之，以有白霜透出时为率，如无白霜
发现，可再 再喷，直至有霜时为止，去纸，入去油乳、没各少许，盖于矾上，离火候冷，取出为末，以面糊为条
备用。用时将此条插入漏孔，待管退出时为度。如于此方之中再加入蝎尾七枚，生草乌末一钱，即为最佳之枯痔药，编
者枯痔时亦常用之。其他外科百效书之“点玄丹”，亦系砒、矾二物，且云善治恶毒，可见此药线一方专作去腐蚀绵
之泛用品，盖顽固腐肉，非仗此种大刀阔斧之猛烈峻剂，实不能去此冥顽不灵之大患也。
此线短处是去腐甚痛，病者多
不乐接受。王肖舫氏则以“蛤豆条”代之，化腐不疼，且极稳妥。其法系以蚊蛤一个，焙至焦黄色，再取生巴豆三粒，
去皮心，焙研细末，加冰片少许，共合一处，调捻为条（以巴豆油质能粘和成条为度，否则须相势加油加药）。此条用时
烂而不疼，功在药线之上。
歌诀说：各家制作的药线都不相同，我们门派的药线有奇特的功效。虽然砒霜和明矾的用法一样，但关键在于火候中辨别雌雄（指火候的掌握）。无论是痰核还是骨槽风，都能起到化腐排脓、显现神通的作用。
（制法）将上述药材分别研成细末。先在锅中滴入几滴麻油，接着放入砒霜粉末，再将明矾粉末覆盖在表面。将锅置于武火（大火）上烧煮，等到砒霜和明矾干燥结成饼状，烟气即将散尽还未完全散尽时，取出并研成粉末，用面糊制成细条（粗细如丝线）备用。经过这种炼制后，砒霜的药性变得纯粹。凡是瘰疬形成硬结，以及痈疽长期不愈合、流脓等情况，都可以使用此药线。
《外科大成》中痔漏退管药线方里，有一方也仅包含砒霜和明矾两味药，只是炼制方法略有不同，此处也摘录下来，以显示此方作用的广泛：白砒五钱，明矾一两五钱。将白砒放入铁锅内铺平，上面覆盖明矾粉末，用火煅烧，等到明矾烧枯时，向砒霜上喷一口冷水，随即用棉纸盖在砒霜上，再向纸上喷三四五口冷水。从锅盖边缘的纸张观察，以有白霜透出为标准。如果没有白霜出现，可以再次喷水，直到出现白霜为止。去掉纸张，加入少许去油的乳香和没药，覆盖在明矾上，离火冷却至冷透，取出研成粉末，用面糊做成细条备用。使用时将此条插入瘘管孔道，待坏死组织脱落排出为止。如果在此方中加入蝎尾七枚、生草乌粉末一钱，就是最佳的枯痔药，编者在使用枯痔疗法时也常用此方。其他《外科百效书》中的“点玄丹”，也是由砒霜和明矾两物组成，并且声称善于治疗恶毒疮疡。由此可见，此药线一方主要作为去除腐蚀绵烂组织的通用药物。顽固的腐肉，非依靠这种大刀阔斧般的猛烈峻剂，实在无法去除这种冥顽不灵的大患。
这种药线的缺点是去腐过程非常疼痛，患者大多不愿意接受。王肖舫先生则用“蛤豆条”来代替，化腐时不疼，而且非常稳妥。其方法是取一个文蛤，焙至焦黄色，再取生巴豆三粒，去皮和心，焙干后研成细末，加入少许冰片，混合在一起，调和捻成条状（以巴豆的油质能够粘合成为条状为度，否则需酌情加油或加药）。此条使用时腐烂而不疼痛，功效优于药线。
The verse states: The medicinal threads prepared by various schools are not identical; our school's medicinal thread possesses miraculous efficacy. Although arsenic (Bai Pi, Realgar) and alum (Ming Fan) are used similarly, the key lies in mastering the fire temperature to distinguish between "yin" and "yang" (referring to the precision of heat control). Whether dealing with phlegm nodules or bone cavity wind, it demonstrates divine power in resolving putrid tissue and draining pus.
(Prescription) Bai Pi (Realgar/White Arsenic) 3 qian, Ming Fan (Alum) 7 qian.
(Method of Preparation) Grind each ingredient into fine powder separately. First, drip a few drops of sesame oil into a pot. Then, place the arsenic powder into the pot, followed by covering it with the alum powder. Heat the pot over vigorous fire (Wu Huo). When the arsenic and alum dry and form a cake, and the smoke is about to dissipate but has not yet completely vanished, remove it from the heat, grind it into powder, and mix with wheat paste to form thin strips (as thick as silk thread) for future use. After this refining process, the toxicity of arsenic becomes pure. It can be used for conditions such as scrofula (Luo Li) forming hard knots, and carbuncles/furuncles that fail to heal for a long time with persistent pus discharge.
In the "Hemorrhoid Fistula Tube-Removing Medicinal Thread Formula" from *Waike Dacheng* (Great Compendium of Surgery), there is another formula containing only arsenic and alum, with slightly different preparation methods. It is excerpted here to demonstrate the broad applicability of this formula: Bai Pi (White Arsenic) 5 qian, Ming Fan (Alum) 1 liang 5 qian. Spread the white arsenic evenly in an iron pot, cover it with alum powder, and calcine with fire. When the alum becomes dry and brittle, spray one mouthful of cold water onto the arsenic. Immediately cover the arsenic with cotton paper, then spray three to five mouthfuls of cold water onto the paper. Observe from the edge of the pot lid through the paper; the process is complete when white frost appears on the paper. If no white frost appears, continue spraying until it does. Remove the paper, add a small amount of de-oiled Commiphora Myrrha Resin (Ruxiang) and Balsam of Tolub? No, Myrrha (Moyao), cover them on top of the alum, remove from heat, cool completely, take out, grind into powder, and form into strips using wheat paste for reserve. When used, insert this strip into the fistula opening, keeping it in place until the necrotic tube/tissue is expelled. If seven scorpion tails and 1 qian of raw Aconitum carmichaelii root powder (Sheng Caowu) are added to this formula, it becomes the optimal formula for cauterizing hemorrhoids. The editor also frequently uses this formula for hemorrhoid cauterization. The "Dian Xuan Dan" (Point Black Elixir) from *Waike Bai Xiao Shu* (Hundred-Efficacy Book of Surgery) also consists of arsenic and alum, and claims to effectively treat malignant toxic sores. This indicates that this medicinal thread serves primarily as a general agent for removing corrosive, rotting tissue. Stubborn necrotic flesh cannot be removed without such a fierce and potent harsh remedy.
The disadvantage of this thread is that the removal of necrotic tissue is extremely painful, and patients are often unwilling to accept it. Mr. Wang Xiaofang replaced it with "Ge Dou Tiao" (Clam-Bean Strip), which resolves necrosis without pain and is very safe. The method involves roasting one clam until scorched yellow, taking three raw Croton tiglium seeds (Sheng Badou), removing the skin and heart, roasting and grinding them into fine powder, adding a small amount of Borneol (Bingpian), mixing them together, and rolling into strips (adjusting the amount of oil or medicine as needed so that the oil from the croton seeds binds the mixture into a strip). When used, this strip causes ulceration without pain, and its efficacy surpasses that of the medicinal thread.