朱丹溪曰∶《局方》五积散，言治产后余血作痛。方中以苍术为君，麻黄为臣，浓朴、枳壳为佐。虽有芍药、
当归之补血，仅及苍术三分之一。且方中言妇人血气不调，心腹撮痛，闭而不行，并宜服之，何不思产后之妇，有
何实耶？血气未充，似难发汗，借曰推陈致新，药性温和，岂可借用麻黄之散，附以苍术、枳壳，虚而又虚，祸
不旋踵矣。
虞天民曰∶问妇人产后诸疾，古方多用四物汤加减，而丹溪独谓芍药酸寒，伐生发之气，禁而不用，何欤？
曰∶新产之妇，血气俱虚，但存秋冬肃杀之令，少春夏生发之气。故产后诸病，多不利于寒凉之剂，大宜温热之
药，以助资始资生之化源也。先哲制四物汤，以芎归之辛温，佐以地芍之寒，是寒温适中，为妇人诸疾妙剂。若
用于产后，必取白芍药，以酒重复制炒，去其酸寒之性，但存生血活血之能，胡不可用也。后人传写既久，脱去
制炒注文。丹溪虑俗医卤莽，不制而用之，故特举其为害之由，以戒之耳。
张景岳曰∶按丹溪云，芍药酸寒，大伐发生之气，产后忌之。此亦言之过也。夫芍
药之寒，不过于生血药中，稍觉其清耳，非若芩连辈之大苦大寒也。使芍药犹忌如此，则他之更寒者，犹为不可
用矣。予每见产家过慎，或因太暖，或因年力方壮，饮食药饵，大补过度，以致产后动火，病热极多。若尽以
产后为虚，必须皆补，岂尽善哉。且芍药性清，微酸而收，最宜于阴气散失之证，岂不为产后要药乎。不可不
解也。
朱丹溪说：《局方》中的五积散，声称治疗产后余血引起的疼痛。该方以苍术为君药，麻黄为臣药，厚朴、枳壳为佐药。虽然方中含有芍药、当归来补血，但其用量仅相当于苍术的三分之一。而且方中说明对于妇人血气不调、心腹拘急疼痛、经闭不通的情况都适宜服用，为何不思考一下产妇体内有什么实邪呢？产后妇女气血尚未充盈，似乎难以承受发汗疗法；即使说是为了推陈致新，且药性温和，岂可借用麻黄的发散之力，再配合苍术、枳壳，使虚弱的身体更加虚弱，灾祸就会立刻降临了。
虞天民说：有人问，妇人产后的各种疾病，古方多使用四物汤加减治疗，而朱丹溪唯独认为芍药酸寒，会损伤生发之气，禁止在产后使用，这是为什么呢？回答说：刚生产完的妇女，气血都虚弱，体内只存有秋冬肃杀之气，缺少春夏生发之气。所以产后的各种病症，大多不利于寒凉的药物，非常适宜用温热的药物，来资助先天和后天的化源。先哲制定四物汤时，用川芎、当归的辛温，配合地黄、芍药的寒凉，使得寒温适中，成为治疗妇人各种疾病的妙方。如果用于产后，必须选用白芍药，用酒反复浸制并炒过，去掉它酸寒的性质，只保留生血活血的功能，怎么不可以使用呢？后人传抄时间久了，脱去了关于“制炒”的注释。朱丹溪担心庸医鲁莽行事，不经过炮制就直接使用，所以特别指出其危害的原因，以此来告诫大家罢了。
张景岳说：按照朱丹溪的说法，芍药酸寒，严重损害发生之气，产后应当禁忌。这也说得太过分了。芍药的寒性，不过是在补血药中稍微显得清冷一些，并不像黄芩、黄连那样大苦大寒。如果芍药都像这样被禁忌，那么其他更寒凉的药物就更不可使用了。我每次见到产妇家属过分谨慎，有的因为过于保暖，有的因为产妇年富力强，饮食和药物进补过度，导致产后动火，患热病的非常多。如果一概认为产后是虚证，必须全部进补，难道就完美无缺了吗？况且芍药性质清润，味微酸而有收敛作用，最适合阴气散失的证候，难道不是产后的要药吗？这一点不能不澄清。
Zhu Danxi stated: The Wuji San (Five Accumulations Powder) from *Ju Fang* claims to treat postpartum pain caused by residual blood. In this formula, Cangzhu (Atractylodis Rhizoma) serves as the sovereign drug, Mahuang (Ephedrae Herba) as the minister drug, and Houpo (Magnoliae Officinalis Cortex) and Zhike (Aurantii Fructus) as the assistant drugs. Although it contains Shaoyao (Paeoniae Radix Alba) and Danggui (Angelicae Sinensis Radix) to nourish blood, their dosage is only one-third that of Cangzhu. Furthermore, the formula states that it is suitable for women with irregular qi and blood, cramping pain in the heart and abdomen, and amenorrhea. Why does it fail to consider what excess pathogenic factors a postpartum woman might have? Since her qi and blood are not yet replenished, she seems ill-suited for diaphoretic therapy. Even if the intention is to eliminate stale matter and generate new tissue, and the medicinal properties are mild, how can one borrow the dispersing power of Mahuang combined with Cangzhu and Zhike, thereby making the deficient body even more deficient, leading to immediate disaster?
Yu Tianmin said: It has been asked why ancient formulas mostly use Siwu Tang (Four Substances Decoction) with modifications for various postpartum diseases, while Zhu Danxi alone considers Shaoyao (Paeoniae Radix Alba) to be sour and cold, damaging the vitalizing qi, and prohibits its use. The answer is: Women who have just given birth have both qi and blood deficiency; they retain only the austere and killing energy of autumn and winter, lacking the vitalizing energy of spring and summer. Therefore, most postpartum conditions are unfavorable to cold-cooling agents and greatly benefit from warm-hot medicines to assist the source of generation for heaven and earth. The sages formulated Siwu Tang (Four Substances Decoction), using the acrid-warm nature of Xiong (Chuanxiong Rhizome) and Gui (Angelicae Sinensis Radix), assisted by the cold nature of Di (Rehmanniae Radix) and Shao (Paeoniae Radix Alba), achieving a balance of cold and warmth, making it an excellent remedy for women's diseases. If used postpartum, one must select Baishaoyao (White Paeony Root), repeatedly soak it in wine and stir-fry it to remove its sour-cold property, retaining only its ability to generate and invigorate blood. How could this be unacceptable? Later copies omitted the notes on processing due to long transmission. Zhu Danxi feared that ordinary physicians would act rashly and use it without processing, so he specifically pointed out the reasons for its harm to warn against it.
Zhang Jingyue stated: According to Zhu Danxi, Shaoyao (Paeoniae Radix Alba) is sour and cold, severely damaging the generating qi, and should be contraindicated postpartum. This statement is excessive. The coldness of Shaoyao is merely slightly cooling among blood-nourishing herbs; it is not as bitter and cold as Huangqin (Scutellariae Radix) or Lian (Coptidis Rhizome). If Shaoyao were to be contraindicated in this manner, then other even colder substances would certainly be unusable. I often see families being overly cautious after childbirth; sometimes due to excessive warming, or because the mother is young and strong, leading to over-supplementation through diet and medicine, causing internal heat and resulting in many cases of extreme heat diseases. If all postpartum conditions are considered deficient and require universal supplementation, is that truly perfect? Moreover, Shaoyao has a clear nature, is slightly sour and astringent, and is most suitable for conditions where yin qi dissipates. Is it not an essential herb for postpartum care? This point requires clarification.