《医录补遗》曰∶妇人血海满则行，然妇人性情执着，比之男子十倍，虽有虚证宜补，亦当以执着为虑，
况月闭一证，大半属血虚气结。
骆龙吉曰∶经云有病胸胁支满，妨于食，病至则先闻腥臊臭，出清液，先吐血，四肢清，目眩，时时前
后血，病名曰血枯。此年少时，因大脱血，或醉而入房，亏损肾肝。盖肝藏血，受天一之气，以为滋荣，其经
上贯膈，布胁肋。若脱血失精，肝气已伤，肝血枯涸不荣，而胸胁满。妨于食，则肝病传脾，而闻腥臊臭，出清
液。若以肝病而肺乘之，则吐血。四肢清，目眩，时时前后血出，皆肝血伤之证也。
虞天民曰∶妇人百病，皆自心生。如五志之火一起，则心火亦从而燔灼。经闭不通之证，先因心事不足，心
血亏耗，故乏血以归肝，而出纳之用已竭。经曰，母能令子虚，是以脾不磨而食少，所谓二阳之病发心脾者，
此也。因食少，故肺气亦失所养。而气滞不行，则无以滋肾阴。况月水全赖肾水施化，肾水既乏，则经水日以
干涸，或先或后，淋漓无时。若不早治，渐至闭塞不通，而必为劳极之证，不易治也。
徐春甫曰∶心属阳而主血，脾裹血以行气。若月经不通，未必不由心事不足，思虑伤脾，有所劳倦，谷气
不输，肺金失养，肾水无滋，经血枯涸，以致三五不调，渐致闭绝。虚损内热，骨蒸劳瘵之证作，而率难以
治。唯养心则血生，脾健则气布，二者和则气畅血行，而调经之要至矣。
《医录补遗》说：妇女的血海充盈时月经就会来潮，然而妇女的性格执着，比男子强烈十倍，即使有虚证应当进补，也应当顾虑其性格执着的问题，何况经闭这一病症，大半属于血虚气结。
骆龙吉说：医经记载有病症表现为胸胁部支撑胀满，妨碍饮食，病发时先闻到腥臊臭味，流出清稀液体，先吐血，四肢发冷，头晕目眩，时常大小便出血，这种病名叫血枯。这是因为年少时，因大量失血，或酒后行房事，导致肾肝亏损。因为肝藏血，受纳天一之气，作为滋养荣润的来源，其经脉上贯膈肌，布散于胁肋。如果脱血失精，肝气已经受伤，肝血枯涸不能荣养，而导致胸胁胀满。妨碍饮食，则是肝病传脾，而出现闻腥臊臭、流清液的症状。如果因肝病而肺金乘袭，则会导致吐血。四肢发冷、头晕目眩、时常大小便出血，都是肝血受损的证候。
虞天民说：妇女的百病，都从心生起。如五志之火一起，心火也随之燃烧灼热。经闭不通的病症，起初是因为心事不足，心血亏耗，所以缺乏血液以归藏于肝，而出纳的功能已经竭尽。医经说，母脏能令子脏虚弱，因此脾不运化而食少，所谓“二阳之病发心脾”，就是这个道理。因为吃得少，所以肺气也失去滋养。而气机滞塞不行，就无法滋补肾阴。何况月经完全依赖肾水的施予和化生，肾水既然匮乏，那么经水就日益干涸，或提前或推后，淋漓不断无定时。如果不尽早治疗，逐渐发展到闭塞不通，必然成为极度劳损的病症，难以治愈。
徐春甫说：心属阳而主司血液，脾包裹血液以运行气机。如果月经不通，未必不是由于心事不足，思虑损伤脾气，有所劳累倦怠，谷气不能输布，肺金失去滋养，肾水得不到滋润，经血枯涸，从而导致月经三五不调，逐渐发展到闭经断绝。虚损内热、骨蒸劳瘵等病症发作，因而大多难以治疗。只有养护心脏则血液滋生，脾脏健运则气机布散，心和脾两者调和则气畅血行，调经的要旨就到了。
According to *Yilu Buiyi* (Supplemental Records of Medical Records): When a woman's Blood Sea is full, menstruation occurs. However, women's temperaments are ten times more stubborn than men's. Even if there are deficiency syndromes requiring tonification, one must consider the issue of stubbornness. Moreover, amenorrhea largely belongs to blood deficiency and qi stagnation.
Luo Longji stated: The medical classics record a condition characterized by distension and fullness in the chest and hypochondrium, interfering with food intake. Upon onset, the patient first smells a fishy or foul odor, secretes clear fluid, experiences hematemesis, cold limbs, dizziness, and frequent bleeding from both the anterior and posterior orifices. This disease is named "Blood Withering" (Xue Ku). This occurs because in youth, due to massive blood loss or intercourse after intoxication, the Kidney and Liver are depleted. Since the Liver stores blood and receives the Qi of Heaven One to provide nourishment, its meridian passes through the diaphragm and spreads over the hypochondrium. If blood is lost and essence is leaked, the Liver Qi is injured, and Liver blood becomes withered and unable to nourish, leading to chest and hypochondriac fullness. Interference with eating indicates that Liver disease transmits to the Spleen, resulting in the perception of fishy/foul odors and secretion of clear fluids. If Lung Metal attacks due to Liver disease, hematemesis occurs. Cold limbs, dizziness, and frequent bleeding from anterior and posterior orifices are all signs of Liver blood injury.
Yu Tianmin stated: All diseases in women originate from the Heart. When the Fire of the Five Emotions arises, Heart Fire burns along with it. In cases of amenorrhea and obstruction, it initially stems from insufficient mental care, depleting Heart Blood, thus lacking blood to return to the Liver, exhausting its functions of reception and discharge. The classics state, "The Mother can cause the Child to be deficient"; therefore, the Spleen fails to transform and transport, leading to poor appetite. This is what is meant by "Diseases of the Two Yangs originating from the Heart and Spleen." Due to poor appetite, Lung Qi also loses nourishment. Qi stagnation prevents the nourishment of Kidney Yin. Furthermore, menstrual water relies entirely on the transformation and distribution of Kidney Water. Once Kidney Water is scarce, menstrual flow dries up daily, occurring irregularly or dripping continuously without time limits. If not treated early, it gradually progresses to complete obstruction, becoming an extreme consumption syndrome that is difficult to treat.
Xu Chunfu stated: The Heart belongs to Yang and governs Blood, while the Spleen envelops Blood to move Qi. If menstruation is obstructed, it may well be due to insufficient mental care, where excessive thinking injures the Spleen Qi, accompanied by fatigue and weariness. Grain Qi is not distributed, Lung Metal loses nourishment, and Kidney Water lacks moistening. Consequently, menstrual blood withers, leading to irregular cycles (every three or five days/months) and eventually complete cessation. Deficiency damage with internal heat, bone-steaming tuberculosis, and other consumptive diseases arise, making them generally difficult to treat. Only by nourishing the Heart will Blood generate; only by strengthening the Spleen will Qi distribute. When these two harmonize, Qi flows smoothly and Blood moves, achieving the essential principle of regulating menstruation.