《巢氏病源》小儿寒热结实候∶外为风邪客于皮肤，而内痰饮渍于腑脏，使血气不和，阴阳交争，则发寒热。
而脏气本实，复为寒热所乘，则积气在内，使人胸胁心腹烦热而满，大便苦难，小便赤涩，是为寒热结实也。
《千金》∶小儿连连壮热，实滞不去，寒热往来，微惊悸方。
大黄（一两） 黄芩 栝蒌根 甘草（炙。各十八铢） 滑石（二两） 桂心 牡蛎 人参 龙骨 凝
水石 白石脂 硝石（各半两）
上十二味 咀，以水四升，煮取一升半。服三合，一日一夜令尽，虽吐亦与之。一本加紫石英半两。
《圣惠》治小儿寒热结实，或热攻冲心，肺气急，昼夜自汗，日渐消瘦，不吃乳食。柴胡丸方
柴胡（去苗） 川大黄（锉碎，微炒） 鳖甲（涂醋炙微黄，去裙 。各半两） 赤茯苓 人
参（去芦头） 木香 桂心 枳壳（麸炒微黄，去瓤） 甘草（炙微赤，锉。各一分）
上件药捣，罗为末，炼蜜和丸如麻子大。每服用温水下五丸，日三服。量儿大小加减服之。
《圣惠》治小儿增寒壮热，发歇不定，腹中结实，不能乳食。大黄丸方
川大黄（锉碎，微炒） 柴胡（去
苗） 槟榔（各半两） 赤茯苓 人参（去芦头） 木香 桂心 枳壳（麸炒微黄，去瓤） 桃仁（汤浸，去皮尖、
双仁，麸炒微黄。各一分）
上件药捣，罗为末，炼蜜和丸如麻子大。每服以温水下五丸，日三服。量儿大小加减服之。
《圣惠》治小儿寒热结实，胁下妨闷，不欲乳食。鳖甲散方
鳖甲（涂醋炙令黄，去裙 ） 赤茯苓 枳壳（麸炒微黄，去瓤。各半两） 川大黄（锉碎，
微炒） 川朴硝（各一两）
上件药捣，粗罗为末。每服一钱。以水一小盏，煎至五分，去滓。放温，不计时候。量儿大小分减温服。
《圣惠》治小儿宿食，痰癖寒热，腑脏结实。宜服芒硝丸方
川芒硝 川大黄（锉碎，微炒） 代赭石（各半两） 甘遂 半夏（汤泡七次，去滑。
各一分） 巴豆（二十枚，去皮、心、膜，纸裹压去油） 杏仁（二、七枚，去皮尖，另研）
上件药捣，罗为末，与巴豆、杏仁膏一处研匀，炼蜜和捣三、二百杵，丸如绿豆大。五、六岁儿空腹以温
水下一丸，以利为度。
《圣惠》治小儿腹有积滞，致生寒热，腑脏结实，心腹气胀，常多少力。五灵脂丸方
五灵脂 木香（各半两） 陈橘皮（三分，汤浸、去白瓤，焙） 川大黄（锉碎，微炒） 巴豆霜（各一分）
上件药捣，罗为末，入巴豆霜同研令匀，用软饭和丸如黍米大。每服以粥饮下两丸，儿小即一丸。
《诸病源候论》中关于小儿寒热结实证的论述：外感风邪侵袭皮肤，内里痰饮浸渍于脏腑，导致气血不和，阴阳相互交争，从而引发寒热症状。
如果脏腑之气原本就充实，又受到寒热邪气的侵袭，致使积气停留在体内，使人出现胸胁心腹部烦热且胀满，大便干结困难，小便短赤涩痛，这就是所谓的寒热结实证。
《千金方》记载：治疗小儿持续高热、实邪积滞不去、寒热往来、轻微惊悸的方剂。
大黄（一两） 黄芩 栝蒌根 甘草（炙。各十八铢） 滑石（二两） 桂心 牡蛎 人参 龙骨 凝水石 白石脂 硝石（各半两）
以上十二味药，切碎，用水四升，煎煮取汁一升半。每次服用三合，一天一夜内服完，即使服药后呕吐，也要继续给予服用。另一版本加紫石英半两。
《太平圣惠方》治疗小儿寒热结实，或者热邪上攻冲心，肺气急促，昼夜自汗，日渐消瘦，不吃奶和食物。柴胡丸方
柴胡（去苗） 川大黄（锉碎，微炒） 鳖甲（涂醋炙微黄，去裙襕。各半两） 赤茯苓 人参（去芦头） 木香 桂心 枳壳（麸炒微黄，去瓤） 甘草（炙微赤，锉。各一分）
以上药物捣碎，过筛成细末，用炼蜜调和制成如麻子大小的丸剂。每次服用温水送服五丸，每日三次。根据患儿年龄大小调整剂量服用。
《太平圣惠方》治疗小儿加重恶寒壮热，发作间歇不定，腹中结实，不能进食乳食。大黄丸方
川大黄（锉碎，微炒） 柴胡（去苗） 槟榔（各半两） 赤茯苓 人参（去芦头） 木香 桂心 枳壳（麸炒微黄，去瓤） 桃仁（汤浸，去皮尖、双仁，麸炒微黄。各一分）
以上药物捣碎，过筛成细末，用炼蜜调和制成如麻子大小的丸剂。每次服用温水送服五丸，每日三次。根据患儿年龄大小调整剂量服用。
《太平圣惠方》治疗小儿寒热结实，胁下痞闷不适，不想吃奶和食物。鳖甲散方
鳖甲（涂醋炙令黄，去裙襕） 赤茯苓 枳壳（麸炒微黄，去瓤。各半两） 川大黄（锉碎，微炒） 川朴硝（各一两）
以上药物捣碎，粗略过筛成粉末。每次服用一钱。用水一小盏，煎至五分，滤去药渣。放温后，不限时间，根据患儿年龄大小分次减量温服。
《太平圣惠方》治疗小儿宿食停滞，痰癖引起的寒热，腑脏结实。适宜服用芒硝丸方
川芒硝 川大黄（锉碎，微炒） 代赭石（各半两） 甘遂 半夏（汤泡七次，去滑腻。各一分） 巴豆（二十枚，去皮、心、膜，纸裹压去油） 杏仁（二、七枚，去皮尖，另研）
以上药物捣碎，过筛成细末，与巴豆、杏仁膏混合一起研磨均匀，用炼蜜调和捣制三、二百杵，制成如绿豆大小的丸剂。五、六岁的儿童空腹用温水送服一丸，以大便通畅为度。
《太平圣惠方》治疗小儿腹部有积滞，导致产生寒热，腑脏结实，心腹部气胀，经常感到乏力。五灵脂丸方
五灵脂 木香（各半两） 陈橘皮（三分，汤浸、去白瓤，焙） 川大黄（锉碎，微炒） 巴豆霜（各一分）
以上药物捣碎，过筛成细末，加入巴豆霜共同研磨均匀，用软饭调和制成如黍米大小的丸剂。每次服用粥饮送服两丸，幼儿则服用一丸。
According to *Zhu Bing Yuan Hou Lun* (Treatise on the Pathogenesis and Symptoms of All Diseases) regarding the syndrome of cold-heat solidification in children: External wind-pathogens invade the skin, while internal phlegm-fluids soak into the zang-fu organs, causing disharmony of qi and blood and contention between yin and yang, thereby manifesting as alternating chills and fever.
If the qi of the zang-organs is originally full and solid, and is further attacked by cold-heat pathogens, accumulated qi remains within the body, causing vexation, heat, and fullness in the chest, hypochondrium, heart, and abdomen; difficulty with dry stools; and scanty, dark, and astringent urination. This is termed the syndrome of cold-heat solidification.
*Qianjin Fang* (Essential Prescriptions Worth a Thousand Gold) records a formula for treating continuous high fever in children, persistent excess stagnation, alternating chills and fever, and mild palpitations with fright.
Da Huang (Rhei Radix et Rhizoma, 1 liang), Huang Qin (Scutellariae Radix), Gua Lou Gen (Trichosanthis Radix), Gan Cao (Glycyrrhizae Radix et Rhizoma Praeparata cum Melle, roasted; each 18 zhu), Hua Shi (Talcum, 2 liang), Gui Xin (Cinnamomi Cortex), Mu Li (Ostrea Concha), Ren Shen (Ginseng Radix et Rhizoma), Long Gu (Fossilia Ossis Mastodi et Scapulae), Ning Shui Shi (Halloysitum Rubrum), Bai Shi Zhi (Kaolinitum), Xiao Shi (Natrii Sulfas; each ban liang).
The above twelve ingredients are crushed. Boil in four sheng of water to obtain one and a half sheng of decoction. Administer three ge per dose, consumed completely within one day and night. Even if vomiting occurs, continue administration. Another version adds Zi Shi Ying (Fluoritum, ban liang).
*Tai Ping Sheng Hui Fang* (State's Holy Welfare Formulary) treats cold-heat solidification in children, or heat pathogen attacking upward to the heart, rapid breathing due to lung qi urgency, spontaneous sweating day and night, progressive emaciation, and refusal of milk and food. Chai Hu Wan (Bupleurum Pill) Formula
Chai Hu (Bupleuri Radix, remove seedlings), Chuan Da Huang (Rhei Radix et Rhizoma, sliced and slightly stir-fried), Bie Jia (Testudinis Carapax et Plastrum, coated with vinegar, roasted until slightly yellow, remove skirt-like edges; each ban liang), Chi Fu Ling (Poria Cocos with Red Mycelium), Ren Shen (Ginseng Radix et Rhizoma, remove rhizome head), Mu Xiang (Aucklandiae Radix), Gui Xin (Cinnamomi Cortex), Zhi Ke (Aurantii Fructus, bran-stir-fried until slightly yellow, remove pith), Gan Cao (Glycyrrhizae Radix et Rhizoma Praeparata cum Melle, roasted until slightly red, sliced; each 1 fen).
Crush the above herbs, sieve into fine powder, and mix with refined honey to form pills the size of hemp seeds. Administer five pills per dose with warm water, three times daily. Adjust dosage according to the child's age and size.
*Tai Ping Sheng Hui Fang* treats aggravated chills and high fever in children, irregular paroxysms, solid accumulation in the abdomen, and inability to take milk and food. Da Huang Wan (Rhubarb Pill) Formula
Chuan Da Huang (Rhei Radix et Rhizoma, sliced and slightly stir-fried), Chai Hu (Bupleuri Radix, remove seedlings), Bing Lang (Arecae Semen, each ban liang), Chi Fu Ling (Poria Cocos with Red Mycelium), Ren Shen (Ginseng Radix et Rhizoma, remove rhizome head), Mu Xiang (Aucklandiae Radix), Gui Xin (Cinnamomi Cortex), Zhi Ke (Aurantii Fructus, bran-stir-fried until slightly yellow, remove pith), Tao Ren (Persicae Semen, soaked in hot water, peel and remove tips and double kernels, bran-stir-fried until slightly yellow; each 1 fen).
Crush the above herbs, sieve into fine powder, and mix with refined honey to form pills the size of hemp seeds. Administer five pills per dose with warm water, three times daily. Adjust dosage according to the child's age and size.
*Tai Ping Sheng Hui Fang* treats cold-heat solidification in children, oppression and stuffiness under the hypochondrium, and reluctance to take milk and food. Bie Jia San (Testudinis Carapax et Plastrum Powder) Formula
Bie Jia (Testudinis Carapax et Plastrum, coated with vinegar, roasted until yellow, remove skirt-like edges), Chi Fu Ling (Poria Cocos with Red Mycelium), Zhi Ke (Aurantii Fructus, bran-stir-fried until slightly yellow, remove pith; each ban liang), Chuan Da Huang (Rhei Radix et Rhizoma, sliced and slightly stir-fried), Chuan Pu Xiao (Natrii Sulfas, each 1 liang).
Crush the above herbs and sieve coarsely into powder. Administer 1 qian per dose. Decoct in one small cup of water until reduced to five fen, strain off the dregs. Allow to cool to warm temperature. Administer at any time, adjusting the amount based on the child's age and size.
*Tai Ping Sheng Hui Fang* treats retained food in children, phlegm-rheum causing chills and fever, and solidification of the fu-zang organs. Mang Xiao Wan (Mirabilite Pill) Formula is suitable.
Chuan Mang Xiao (Natrii Sulfas), Chuan Da Huang (Rhei Radix et Rhizoma, sliced and slightly stir-fried), Dai Zhe Shi (Haematitum, each ban liang), Gan Sui (Kansui Radix), Ban Xia (Pinelliae Tuber, soaked in hot water seven times to remove slipperiness; each 1 fen), Ba Dou (Crotonis Fructus, twenty seeds, peel, remove heart and membrane, wrap in paper and press to remove oil), Xing Ren (Armeniacae Semen, two or seven seeds, peel and remove tips, grind separately).
Crush the above herbs and sieve into fine powder. Mix with the paste of Ba Dou and Xing Ren, grind uniformly, mix with refined honey, and pound three to two hundred times to form pills the size of mung beans. For children aged five or six years, administer one pill on an empty stomach with warm water, stopping when bowel movement becomes loose.
*Tai Ping Sheng Hui Fang* treats abdominal stagnation in children leading to chills and fever, solidification of fu-zang organs, abdominal distension with qi, and frequent fatigue. Wu Ling Zhi Wan (Trogopteri Excrement Pill) Formula
Wu Ling Zhi (Trogopteri Excrement), Mu Xiang (Aucklandiae Radix, each ban liang), Chen Ju Pi (Citri Reticulatae Pericarpium, 3 fen, soaked in hot water, remove white pith, dried), Chuan Da Huang (Rhei Radix et Rhizoma, sliced and slightly stir-fried), Ba Dou Shuang (Crotonis Fructus Pulvis, each 1 fen).
Crush the above herbs and sieve into fine powder. Add Ba Dou Shuang and grind uniformly. Mix with soft rice to form pills the size of millet grains. Administer two pills per dose with gruel broth; for smaller infants, administer one pill.