予高友少年不慎，尝发梅疮，治不如法，以致毒瓦斯内伏，外虽愈而内成结毒。每夏月则手心多现紫疹，如鹅
掌风样。及其生子，皆于月内二十七日必发此毒。初从阴囊之下，红 数点，似火丹之状；不数日，则延及遍
体，皮肉溃烂，形类火烧，昼夜啼号，诸药莫救；延至半月，则精神竭脱而死。连生三子，有如一辙，友悔恨无
及，力恳于予。予虽感其诚敬，而实不得其法，因静思熟计，恍然有得。盖此毒从泄精后，乘虚透入命门，直灌
冲脉，已为负隅之虎矣，而且盘踞多年，根深蒂固，何可动摇！倘剿捕不得其法，反致蹂躏疆场，损我民物。古
人云∶多算胜，少算不胜。苟非攻坚破垒，捣巢覆穴，不足以绝其根株。因自制一方，名窜毒丸。以鲮鲤甲头尾、
胸脊以及四足，各用鳞甲数片，取其穿山透穴，率领诸药，直趋毒巢，则内而脏腑，外而经络，凡冲脉所行之地，
无处不到，以之为君；用刺猥皮仍以上法，各取其刺，虽搜毒之功不如鲮鲤，而以毒攻毒，力则过之，故以为臣；
用蝉蜕、蛇蜕，虽为解毒清热之需，实所以取其蜕脱之义，以之为佐；以芩、连、栀、柏清其雷龙之火，用皂刺、
土苓、槐花领毒外出，不使久留精窍，以之为使；复略加人参护其胃气，使之宣行药力，庶无溃乱壅遏之虞，以
为四路救应。制而服之，诚所谓得心应手，针芥相投，药未尽而毒出。忽于左脚 发一恶疮，皮肉紫黑，痛苦异常，
号呼床第，一月方痊。嗣是手掌如故，所生子女，不特不发梅疮，而并毫无疥癣。可见病有万殊，理无二致。予
素未谙外科，而能拔兹社鼠城狐之毒，恃此理也；倘无其理，而欲邀天之幸，吾未能信。
小儿梅疮，最为恶候，倘发于一二月间，或半岁之内，最难救治。以其毒禀先天，来路既远，方药难及，即
日服数匙之药，杯水车薪，终难有济。昧者但以搽洗之法治之，适
足以阻其出路，反致内攻不救。只当缓以图之，庶能保全。先以胡麻丸修制精细，每日服之，三七之后，内毒将
尽，方用点药，不三日而疮尽愈矣。此法至神至捷，第不可用之太早，恐内毒未尽也。
我的高姓好友年轻时行为不慎，曾经患过梅毒（梅疮），治疗不规范，导致毒邪内伏。虽然外表看似痊愈，但体内形成了结毒。每到夏季，他的手掌心就会多处出现紫红色皮疹，形状像鹅掌风一样。当他生子时，孩子们都在出生后二十七天必定发作这种毒症。起初从阴囊下方开始，出现几处红点，类似火丹的样子；没过几天，就蔓延到全身，皮肉溃烂，形态像被火烧过一样，日夜啼哭号叫，各种药物都无法救治；拖延到半个月，就会精神耗尽而死亡。他连续生了三个儿子，情况如出一辙，朋友悔恨莫及，极力恳求我救治。
我虽然感激他的诚恳恭敬，但实际上并没有找到治疗方法，于是静心深思，突然有所领悟。大概这种毒邪是在泄精之后，趁着身体虚弱侵入命门，直接灌注冲脉，已经成为占据险要之地的猛虎了，而且盘踞多年，根深蒂固，怎么可以轻易动摇！如果剿灭的方法不得当，反而会导致战场被践踏，损害百姓财物。古人说：多谋划能取胜，少谋划不能取胜。如果不是攻坚破垒，捣毁巢穴，不足以断绝其根株。因此我自制了一个方剂，名叫“窜毒丸”。用穿山甲（鲮鲤）的头尾、胸脊以及四足的鳞片各数片，取其穿透穴位之意，率领其他药物，直趋毒巢，那么在内而脏腑，在外而经络，凡是冲脉运行的地方，无处不到，以此作为君药；用刺猬皮仍然按照上述方法，各取其刺，虽然搜刮毒邪的功效不如穿山甲，但以毒攻毒，力量却超过它，所以作为臣药；用蝉蜕、蛇蜕，虽然是解毒清热的需要，实际上是取其蜕壳脱变的意义，以此作为佐药；用黄芩、黄连、栀子、黄柏清除雷龙之火，用皂角刺、土茯苓、槐花引导毒邪排出体外，不让其久留于精窍，以此作为使药；再略微加入人参保护胃气，使其宣行药力，从而没有溃乱壅塞的担忧，作为四路救应。制成并服用后，确实可以说是得心应手，针芥相投，药还没吃完毒邪就排出了。忽然在左脚发出一个恶疮，皮肉紫黑，痛苦异常，在床上号呼，一个月才痊愈。从此以后手掌恢复正常，所生的子女，不仅不发作梅毒，而且完全没有疥癣等皮肤病。可见病情有万种不同，道理却没有两样。我向来不懂外科，却能拔除这种社鼠城狐般的毒邪，依靠的就是这个理；如果没有这个理，而想侥幸成功，我是不会相信的。
小儿梅毒，是最为凶险的证候，如果在出生一两个月间，或者半岁之内发作，最难救治。因为它的毒邪禀受于先天，来路既远，方药难以到达，即使每天服用几匙药，也是杯水车薪，终究难以奏效。无知的人只用外搽清洗的方法治疗，恰好阻断了毒邪的外出路径，反而导致毒邪内攻无法救治。只应当缓慢地图谋治疗，或许能够保全生命。先用胡麻丸精细修制，每日服用，三七天后，体内毒邪将尽，再用点药，不过三天疮口就全部愈合了。这种方法极其神奇快捷，只是不可使用得太早，恐怕体内毒邪尚未排尽。
My high-ranking friend, in his youth, was not careful in his conduct and once contracted syphilis (Meichuang). Due to improper treatment, the pathogenic toxin became internally latent. Although it appeared cured externally, a nodular toxin formed internally. Every summer, purple rashes would appear on the palms of his hands, resembling the appearance of Goose Palm Wind (Ezhangfeng). When he had children, all of them would inevitably manifest this toxin within twenty-seven days after birth. Initially, several red spots would appear below the scrotum, resembling Fire Dan (Huodan); within a few days, it would spread over the entire body, with skin and flesh ulcerating, looking as if burned by fire. The infants would cry and wail day and night, and various medicines failed to save them; after half a month, they would die from exhaustion of spirit and vitality. This happened consecutively to three sons, exactly the same each time. My friend was filled with regret and remorse, and earnestly begged for my help.
Although I appreciated his sincerity and respect, I initially did not know the method. Thus, I pondered quietly and deeply, and suddenly gained insight. It seems that this toxin entered the Mingmen Gate (Gate of Life) through deficiency after seminal emission, directly flooding the Chong Mai (Penetrating Vessel), becoming like a fierce tiger entrenched in a stronghold. Having occupied this position for years, its roots were deep and firm, making it difficult to dislodge! If the suppression method is incorrect, it will only trample the battlefield and harm the people. As the ancients said: "Much calculation leads to victory; little calculation leads to defeat." Unless one attacks strongholds and destroys nests, one cannot eradicate the root cause. Therefore, I formulated a prescription named "Cuan Du Wan" (Toxin-Expelling Pill). I used scales from the head, tail, chest, back, and four feet of Pangolin (Lingli Jia, 鲮鲤甲), taking several scales from each part, to utilize their penetrating properties to lead other herbs directly to the toxin's nest. Thus, reaching everywhere inside the Zang-Fu organs and outside in the meridians, wherever the Chong Mai travels, this serves as the Sovereign herb. I also used Hedgehog Skin (Ciwei Pi, 刺猬皮) prepared similarly, taking its spines; although its power to search out toxins is inferior to Pangolin, its ability to attack toxin with toxin is superior, so it serves as the Minister herb. Cicada Slough (Chantui, 蝉蜕) and Snake Slough (Shetui, 蛇蜕) are used; while needed for detoxification and clearing heat, their primary symbolic meaning here is shedding/transformation, serving as the Assistant herb. Huangqin (Scutellariae Radix, 黄芩), Huanglian (Coptidis Rhizoma, 黄连), Zhizi (Gardeniae Fructus, 栀子), and Huangbai (Phellodendri Cortex, 黄柏) are used to clear the Fire of Lei Long (Thunder Dragon); Zaocys Spine (Zaoci Ci, 皂刺 - note: usually refers to Gleditsiae Spina or similar thorns, here likely referring to specific thorny herbs for guiding out toxins, text says Zao Ci), Tufuling (Smilacis Glabrae Rhizoma, 土苓), and Huaihua (Sophorae Flos, 槐花) are used to guide the toxin outwards, preventing it from lingering in the essence apertures, serving as the Envoy herb. A slight addition of Renshen (Ginseng Radix et Rhizoma, 人参) protects Stomach Qi, facilitating the distribution of medicinal power, avoiding collapse or stagnation, acting as reinforcements from four directions. After preparation and administration, it was indeed as if the hand and heart were coordinated, needles and buttons matching perfectly; before the medicine was exhausted, the toxin was expelled. Suddenly, a malignant sore erupted on the left foot, with purple-black skin and flesh, causing extreme pain and wailing in bed, healing only after one month. Thereafter, the palms returned to normal, and the children born subsequently not only did not contract syphilis but also had no scabies or tinea. This demonstrates that diseases may vary infinitely, but the underlying principles remain consistent. I have never been proficient in external medicine, yet I could eradicate such venomous toxins like rats in the shrine or foxes in the city, relying solely on this principle; without this principle, hoping for heaven's luck, I would not believe it.
Pediatric syphilis is the most severe condition. If it manifests within one or two months of birth, or within half a year, it is extremely difficult to treat. Because the toxin is inherited from the congenital source, the path is long, and medicinal formulas struggle to reach it. Even administering several spoonfuls of medicine daily is like adding a cup of water to a cartload of burning wood—ultimately ineffective. Ignorant practitioners merely use topical washing methods, which inadvertently block the exit path of the toxin, leading to internal attack and untreatable conditions. One should instead adopt a gradual approach to preserve life. First, administer finely prepared Huma Wan (Sesame Pill), taken daily. After thirty-seven days, when internal toxins are nearly exhausted, apply point-treatment medicines. Within three days, the sores heal completely. This method is miraculous and rapid, but must not be applied too early, lest the internal toxins remain unexhausted.