饮食入胃，多停中脘。中脘乃盛水谷之海、上脘只纳食，行水谷，所化精悍之气，上输于肺，下脘消
化糟粕，入大小之肠。如食入于肠胃有停留不化者，有食物已去而害其脾胃转运之气者，有因之而致其清浊
不分者。三脘者，则皆恶食，其物停留三脘有轻重。重在中下，则大小承气、备急丸之类；轻在中下，则枳
术丸之类。食纳上脘，未入中脘而伤之重者，而出之；其已入中脘，而食物塞之，其气反壅于下脘，致
气口脉大于人迎二、三倍者，亦必吐之。经曰∶上部有脉，下部无脉，其人当吐不吐者死。若物已去而脾
胃中元气受伤者，则东垣内伤补益之法是矣。所谓食伤胸中如有物者，非所食谷肉之物，由饮食过度，消
化之气清浊不分，溷乱之液自上脘至胸中，积成痰饮，乃伤之轻者，故宜厘清浊、化痰饮、和中益胃、开
郁则郁。
丹溪取醉仙、再造，以分上下用也。《内经》曰∶脉风成，为 风。又曰∶风寒客于肺而不去，
名风。 风者，荣卫热 ，其气不清，故使鼻柱坏而色败，皮肤疡溃。又谓风气与太阳俱入，行诸脉
俞，散诸分肉之间，与卫气相干，其道不利，故使肌肉 而有疡，卫气有所凝而不行，故其肉有不仁
也。《刺长节论》曰∶病大风，骨节重，须眉堕，刺肌肉，汗出百日。（王注）泄卫气之怫热，刺骨髓，
汗出百日。（王注）以泄荣气之怫热，凡二百日，须眉生而止。《灵枢》曰∶ 风者，数刺其肿上，以
锋针针其处，按出其恶气，肿尽乃止，当食方食，毋食他食。经论分荣卫者，如此古方，但混泄风热于
荣卫，又无先后之分，惟《活法
机要》用桦皮散治其卫，二圣散治其荣。二圣即再造也，出《三因方》。先生言再造用郁金半两，
白丑六钱（半生半炒），皂角刺（经年黑大者）。今选二方，分气血上下先后而用。盖以气为阳为卫，
血为阴为荣。身半以上，阳先受之∶身半以下，阴先受之。再造治其病在阴者，用皂刺出风毒于荣血中。肝
主纳血，恶血留止属于肝也。虫亦主于厥阴风木所化，须是治其脏气，杀虫为主，以大黄引入肠胃荣血
之分，利下恶血虫物。醉仙散治其病在阳者，用鼠粘子出风毒遍身恶疮，胡麻逐风、补肺、润皮肤，蒺藜主
恶血、身体风痒、通鼻气，防风治诸风，栝蒌根治瘀血、足热 肿，枸杞消风毒热、散疮肿，蔓荆子主贼风，
苦参治热毒风、皮肌烦躁生疮、赤癞眉脱，八味治风至矣！然必银粉为使，乃下膈通大肠要剂，用其驱药入
阳经，开风热怫郁痞结，逐出恶气臭秽之毒，杀所生之虫，随经上行至牙齿嫩薄之分，出其臭毒之涎水。此
药伤齿，则以黄连末揩之，或先固济以解银粉之毒，银粉在醉仙散有夺旗斩将之功，遂成此方之妙用，非他方
可及。余邪未除，但调和荣卫药中少加驱逐耳！
一人面浮油光，微肿色变，眉脱，痒。二世疠风
死者三人。与醉仙散，出涎水如盆而愈。
一人面肿，色变黑，燥痒，眉须脱落，手足皮燥浓折，痛痒无全肤，有时痒入骨髓，抓至血出，
稍止复作，昼夜不眠，与二药则愈。
一妇两足胫疮溃，眉落，与再造散一服愈。年少不能断欲、忌口，一年复发。其前二人不复发者，
非能如法调摄，由病得之未深，鼻柱未坏，疮未溃 故耳！故人抱病，不可不早治也。
饮食进入胃中，大多停滞在中脘部位。中脘是容纳水谷的枢纽，上脘主要负责接纳食物、运行水谷，将所化生的精悍之气向上输送到肺；下脘负责消化糟粕，将其送入大小肠。如果食物进入肠胃后出现停留不消化的情况，或者食物虽然已经排空但损害了脾胃转运的气机，又或者因此导致清浊之气不分，这三脘（上脘、中脘、下脘）都会厌恶食物，食物在三脘停留的程度有轻有重。如果病位偏重于中脘和下脘，则使用大承气汤、备急丸之类的方剂；如果病位较轻且位于中下焦，则使用枳术丸之类的方剂。如果食物停留在上脘，尚未进入中脘但损伤较重，应当采用催吐法排出；如果食物已经进入中脘，并且堵塞气机，导致气机反而壅滞在下脘，致使气口脉象比人迎脉大二至三倍的情况，也必须采用催吐法。医经说：上部有脉搏，下部无脉搏，病人应当呕吐而不能呕吐的，会死亡。如果食物已经排空，但脾胃中的元气受到损伤，那么就应该采用李东垣治疗内伤补益的方法。所谓“食伤胸中感觉像有东西堵着”，并不是因为吃的谷物肉类本身造成的伤害，而是因为饮食过度，消化之气导致清浊不分，浑浊的液体从上脘流窜到胸中，积聚形成痰饮，这是损伤较轻的情况，所以适宜用厘清清浊、化痰饮、调和脾胃、开解郁结的方法治疗。
朱丹溪选取醉仙散和再造散，是为了区分上下部位来用药。《黄帝内经》说：脉象受风邪影响而形成的病症，称为疠风。又说：风寒邪气客居在肺脏而不离去，也称为疠风。疠风这种病，是由于营卫之气热盛，其气不清爽，所以会导致鼻梁塌陷、面色败坏、皮肤生疮溃烂。又认为风气与太阳经一同侵入，行走在各经脉的俞穴，散布在分肉之间，与卫气相互干扰，导致经络通道不利，所以使肌肉发生病变而生疮疡；卫气有所凝滞而不能运行，所以肌肉会出现麻木不仁的现象。《刺节真邪论》说：患大风病，骨节沉重，眉毛胡须脱落，针刺肌肉部位，出汗一百天。（王冰注）泄除卫气的郁热，针刺骨髓部位，出汗一百天。（王冰注）泄除营气的郁热，总共二百天，眉毛胡须生长出来才停止。《灵枢》说：对于疠风，多次针刺肿胀处，用锋针在该处针刺，按压排出恶气，直到肿胀消退为止，应当按时进食，不要食用其他食物。医经论述区分营卫的方法如此，但古方只是混合地泄除荣卫的风热，又没有先后顺序之分，只有《活法机要》用桦皮散治疗卫分，二圣散治疗营分。二圣散就是再造散，出自《三因极一病证方论》。先生言再造散使用郁金半两，白牵牛六钱（一半生用一半炒制），皂角刺（陈年黑色粗大的）。现在选择这两个方子，分别针对气血、上下、先后的不同来使用。大概因为气属阳为卫，血属阴为荣。身体上半部，阳气先受邪；身体下半部，阴气先受邪。再造散治疗病在阴分的，使用皂角刺将风毒从营血中引出。肝主收纳血液，瘀血留止归属于肝。虫类也主于厥阴风木所化生，必须治疗其脏腑之气，以杀虫为主，配合大黄引入肠胃营血之分，利下瘀血和虫物。醉仙散治疗病在阳分的，使用牛蒡子将风毒遍身恶疮引出，胡麻祛风、补肺、润皮肤，蒺藜主治恶血、身体风痒、通鼻气，防风治疗各种风邪，栝楼根治疗瘀血、足热肿胀，枸杞消除风毒热、消散疮肿，蔓荆子主治贼风，苦参治疗热毒风、皮肌烦躁生疮、赤癞眉脱，这八味药治风效果显著！但是必须以银粉作为引经药，它是下膈通大肠的要剂，用它驱赶药物进入阳经，开泄风热郁结痞块，驱逐出恶气臭秽之毒，杀死所生的虫类，随经络上行到达牙齿嫩薄之处，排出臭毒的涎水。此药会损伤牙齿，可以用黄连末擦拭，或者事先固护牙齿以解除银粉的毒性。银粉在醉仙散中有夺旗斩将的功效，从而成就了此方的妙用，不是其他方剂可以比拟的。余邪未除时，只需在调和营卫的药物中少量加入驱逐邪气的药物即可。
有一人面部浮肿油光，轻微肿胀变色，眉毛脱落，瘙痒。他家两代有三人死于疠风。给予醉仙散，吐出如盆的涎水而痊愈。
有一人面部肿胀，颜色变黑，干燥瘙痒，眉毛胡须脱落，手足皮肤干燥脓裂，痛痒遍布全身没有完好皮肤，有时痒感深入骨髓，抓挠至出血，稍作缓解后又发作，昼夜无法入睡，给予这两种药物后痊愈。
有一位妇女双小腿疮疡溃烂，眉毛脱落，服用一服再造散后痊愈。这位妇女年轻，不能节制性欲、忌口，一年后复发。前面两人不再复发的原因，并非他们能依法调养摄生，而是因为病情得之尚浅，鼻梁未塌陷，疮疡未溃烂的缘故啊！所以人患病，不可不早治。
Food enters the stomach and mostly stagnates in the Zhongwan (CV12) area. Zhongwan is the hub for containing water and grain; Shangwan (upper part of the stomach) is mainly responsible for receiving food and transporting water and grain, sending the refined and vigorous qi generated upwards to the Lung; Xiawan (lower part of the stomach) is responsible for digesting dregs and sending them into the large and small intestines. If food entering the stomach and intestines remains undigested, or if the food has been expelled but damages the transportive qi of the Spleen and Stomach, or if it causes a failure to distinguish between clear and turbid substances, all three parts of the stomach (Shang, Zhong, and Xia) will reject food. The degree of food stagnation in these three areas varies. If the pathology is heavier in the middle and lower parts, formulas such as Dachengqi Tang (Major Order the Qi Decoction) or Beiji Wan (Emergency Aid Pill) should be used; if the pathology is lighter and located in the middle and lower jiao, formulas such as Zhizhu Wan (Immature Bitter Orange and Atractylodes Pill) should be used. If food remains in Shangwan without entering Zhongwan but causes severe damage, emesis should be induced to expel it. If food has entered Zhongwan and blocks the qi mechanism, causing qi to stagnate in Xiawan, resulting in the Qikou (Radial Artery at the wrist) pulse being two to three times larger than the Renying (Carotid Artery) pulse, emesis must also be induced. The Classics state: "If there is a pulse in the upper part but none in the lower part, and the patient should vomit but cannot, death will ensue." If the food has already been expelled but the primordial qi of the Spleen and Stomach is injured, then Li Dongyuan's methods for treating internal injury with tonification should be adopted. The phrase "food injury feels like something blocking the chest" does not refer to harm caused by the grains or meats themselves, but rather to excessive eating causing a failure of digestion to distinguish clear from turbid substances. Turbid fluids flow from Shangwan to the chest, accumulating to form Phlegm-Fluids (Tan Yin). This is a mild form of injury, so treatment should focus on clarifying clear and turbid substances, resolving Phlegm-Fluids, harmonizing the Middle Jiao and benefiting the Stomach, and opening up depression.
Zhu Danxi selected Zuixian San (Drunken Immortal Powder) and Zaizao San (Recreate Life Powder) to differentiate usage based on upper and lower regions. The *Neijing* states: "Pulse changes due to wind pathogen constitute Li Feng (Leprosy)." It also says: "When Wind-Cold lodges in the Lung and does not depart, it is named Li Feng." Li Feng arises because Ying and Wei Qi are hot and impure, leading to collapse of the nasal bridge, deterioration of complexion, and ulceration of the skin. It is further stated that Wind pathogen enters together with the Taiyang channel, travels through various Shu points, and scatters between the muscle layers. It interferes with Wei Qi, obstructing its pathway, thus causing lesions in the muscles and ulcers. When Wei Qi coagulates and fails to circulate, the flesh becomes insensible (Anren). The *Cijie Zhenxie Lun* states: "In cases of severe wind disease, bone joints feel heavy, eyebrows and beard fall out. Needling the muscle layer induces sweating for 100 days." (Wang Bing's commentary: To vent the stagnant heat of Wei Qi.) "Needling the bone marrow induces sweating for 100 days." (Wang Bing's commentary: To vent the stagnant heat of Ying Qi.) After a total of 200 days, eyebrows and beard grow back, and treatment stops. The *Lingshu* states: "For Li Feng, frequently needle the swollen areas with a Feng Zhen (Sharp Needle), press to expel evil qi, and stop when swelling subsides. Eat regular meals and avoid other foods." The Classics discuss distinguishing Ying and Wei thus, but ancient formulas merely mixedly vented Wind-Heat in Ying and Wei without distinguishing sequence. Only the *Huofa Jiyao* used Huapi San (Birch Bark Powder) to treat the Wei level and Ersheng San (Two Sages Powder) to treat the Ying level. Ersheng San is identical to Zaizao San, originating from the *Sanyin Fang*. The Master stated that Zaizao San uses Yu Jin (Curcuma Rhizome) half liang, Bai Chou (White Morning Glory Seed) six qian (half raw, half stir-fried), and Zaojiao Ci (Gleditsia Spine, preferably aged black and large). Now, selecting these two formulas to use separately according to Qi/Blood, Upper/Lower, and Sequence/Precedence. Generally, Qi is Yang and Wei; Blood is Yin and Ying. The upper half of the body is first affected by Yang pathogens; the lower half by Yin pathogens. Zaizao San treats pathology in the Yin level, using Gleditsia Spine to expel Wind-Toxin from the Ying-Blood. The Liver governs the storage of blood, and stasis belongs to the Liver. Parasites are also transformed by Jueyin Wind-Wood. Treatment must address the Zang organ qi, prioritizing parasite elimination, assisted by Dahuang (Rhubarb Root) to enter the Intestines' Ying-Blood division, promoting the purgation of stasis and parasites. Zuixian San treats pathology in the Yang level, using Niuzi (Burdock Fruit) to expel Wind-Toxin from generalized bad sores, Hema (Sesame Seed) to dispel wind, benefit the Lung, and moisten the skin, Jili (Tribulus Fruit) to treat stasis, body wind-itch, and unblock nasal qi, Fangfeng (Saposhnikovia Root) to treat various winds, Gualou Gen (Trichosanthes Root) to treat stasis and heat/swelling of the feet, Gouqi (Goji Berry) to eliminate wind-toxin heat and dissipate sores, Jingzi (Vitex Fruit) to treat thief-wind, Kushen (Sophora Root) to treat heat-toxic wind, restlessness of skin/muscle with sores, and red leprosy with eyebrow loss. These eight ingredients effectively treat wind! However, Yinfen (Calomel) must be used as an adjuvant; it is a crucial agent for descending through the diaphragm and unblocking the Large Intestine. It drives the medicinal herbs into the Yang channels, opens wind-heat stagnation and痞结 (masses), expels foul-smelling toxic qi, kills parasites, and ascends along the channels to the tender/thin parts of the teeth to expel foul saliva. This drug damages teeth; one can wipe with Huanglian (Coptis Rhizome) powder, or protect the teeth beforehand to neutralize Yinfen toxicity. Yinfen plays a decisive role in Zuixian San, creating its unique efficacy, unmatched by other formulas. For residual pathogens, simply add a small amount of expelling agents to formulas that harmonize Ying and Wei.
One patient had a puffy, oily face, slight swelling and discoloration, eyebrow loss, and itching. Three members of his family across two generations died of Leprosy. He was given Zuixian San, and after vomiting basin-fulls of saliva, he recovered.
Another patient had facial swelling, blackish discoloration, dry itching, loss of eyebrows and beard, dry and cracked skin on hands and feet with pus, pain and itching covering the whole body with no intact skin. Sometimes the itch penetrated to the bone marrow, scratching until bleeding provided slight relief before recurrence. He suffered from insomnia day and night. He recovered after being given these two drugs.
A female patient had ulcerated sores on both calves and lost her eyebrows. She recovered after taking one dose of Zaizao San. However, being young, she failed to abstain from sexual activity and dietary restrictions, leading to relapse after one year. The reason the previous two patients did not relapse was not because they followed regulation methods perfectly, but because their disease was shallow, the nasal bridge had not collapsed, and the sores had not ulcerated. Thus, when one contracts a disease, early treatment is essential.