脓者，血之变也。痘疮初出，一点血耳，渐起渐长，则由血成浆，由浆成脓，始成实矣。故有
血则有脓，无血则无脓也。痘至灌脓，大势已成，此时必以有脓为主，有脓则生，无脓则死，乃必
然之理也。故六日以前，有热则宜解毒，无热则宜调养血气，至此自然灌脓。若痘至七日以后，顶
陷不能灌脓者，必由先失调治故也，所以治不可缓，必俟浆足，斯可回生。若顶陷灰白，浆脓不至，
此气血俱离，无生意矣。
一、痘疮灌脓，专以脾胃为主，脾胃强则气血充实，脓浆成而饱满坚浓，不须服药；脾胃弱则血
气衰少，所以不能周灌，故虽见浆而浆亦不满，或清淡灰白不能作脓，即所蓄微浆，仍是初时之血
水。而浆薄无以化脓者，总属血气大虚之候，若不速治，必成内攻外剥之证，宜急用六物煎，或六
气煎加减治之，或保元汤、或十全大补汤加人乳、好酒与服亦妙。欲辨脾胃强弱，当于饮食二便察
之。饮食虽少而大便坚者，脾胃之气犹可也，但微加调补，以能食为贵。若大便不实，或见溏泻，
则最为可畏。盖一泻则浆停，泻止则灌满矣。速宜用温胃饮，甚者用陈氏十二味异功散主之。如痘
当作脓之时，犹是空壳，此血不附气也。血既不至，则毒何由化？宜五物煎，或四物汤，或紫草散
加蝉蜕主之。如顶陷脓少，或服内托药而暂起复陷者，血气大虚故也，宜十全大补汤倍加参、 、
当归、糯米，煎成和人乳、好酒服之，此助灌之妙法也。
一、灌脓三朝之内，若身凉而痘色灰白，或不进饮食，或寒气逆上而为呕吐，或腹胀，或泄泻
而手足逆冷，此皆纯阴无阳之证也，急宜用保元汤加二仙散，连进数服；甚者必须九味异功煎，或
陈氏十二味异功散，皆可择用。若寒战切牙泄泻等证，俱同此治。
一、手足灌脓饱满者，方见脾胃之强，气血之足也。若色见灰白，浆水清薄，或瘪 不起者，
此必脾胃之弱也。或灌浆已完，而四肢犹有不灌者，恐终变痒 之证，宜快斑越婢汤，或六气煎加
防风、白芷以达之，
庶无陷伏之患。若毒有未透，亦恐关节之处，靥后致生痈毒。
一、痒 不止者，虽曰气血俱虚，然亦由火力不足，故不作痛而作痒也，宜六气煎，或五物煎
加防风、白芷、木香、蝉蜕主之。《心鉴》曰∶气愈虚则愈痒，当用保元汤倍黄 以助表，少加芍
药以制血，其痒自止。若将靥发痒，此毒退血活，新肉和畅，自然之理也，不必治之。
一、灌脓痛楚不止者，气滞也，少下保元汤加山楂、木香以行滞气。如脓色盛满，大下四苓散
利之而痛自止。
一、痘疮起发之后，不作脓有四证∶有内虚而不灌者，专宜托补气血，治法如前。有感风寒，
邪居肤腠而不灌者，宜温散之，以柴葛桂枝汤加黄 、白芷。有热毒炽盛身壮热，津液干涸，小便
赤热而不灌者，宜托里解毒利小便，以紫草饮子，或用辰砂六一散解之，俟热退后，方可用保元汤。
热甚者，大连翘饮。若大便坚热，数日不通而不灌者，宜猪胆导之，使气得疏通，则营卫和畅，不
然恐成黑陷也。有触秽气而不灌者，外宜熏解，用胡荽酒，或辟邪丹，内服紫草木香汤，或紫草快
斑汤。
程氏曰∶凡顶陷无脓者为逆，但得根窠红润，血犹不散，急用保元汤和芎、归、白芍、丁香、
糯米煎熟，加人乳、好酒温服。若色白如水晶，内无脓者，治亦同。但得脓痘相间者犹可治，若纯
是水晶色者决死。若地红血散有热者，去丁香，加白芍、地骨皮以敛血退热。若寒战切牙，宜以木
香散，异功散选用。
程氏曰∶凡正壮之时，有痘虽起壮而皮肤无力，按之水浆就出，虽肉色不暗，此乃名为假壮，
至十一、二日决不能回浆结靥，内攻而死，可急用保元汤加丁香、川芎、糯米，提气
灌脓自愈。此即名内托也。凡内托之法，即保元汤加川芎、丁香便是，不必《千金》内托也，但
按本方佐使用之。
一、痘将灌脓之时，忽面上有干靥者，即倒陷证也，宜速用八珍汤或六物煎加金银花、牛蒡
子、连翘、麻黄之属，水煎熟，调独圣散服之。服药后，若干者复起作脓，未干者即壮而饱满，或
空地处再出补空小痘者上
也。若痘不作脓，空处或发痈毒者次也。若连进三服而干者不肿，未干者不饱满，补痘不多，则最
险证也，宜以十全大补汤加金银花调治之。
一、灌脓时发白泡如弹子者，用枣针刺去其水，外以滑石末敷之，内服保元汤加石榴皮、茯苓
以利皮肤之水。如发紫泡，乃毒溢皮肤之上也，此证必危。
一、疮烂成片，脓水不干者，用滑石末敷之，或收草散敷之，加珍珠尤妙。
一、痘疮有重出者，凡痘疮破损溃烂处，但得复肿复灌，不致干枯，或于原无痘处复出一层，如
初用之状，亦以渐起发灌脓者，此皆余毒未尽，赖里气充实，毒不得入，故犹出于表而不成倒陷，
是皆逆中之顺证也。但痘疮重出一番，必其人能食而大便坚，乃足以胜其再作之毒，自无足虑也。
如食少而大便润者，宜用十全大补汤之类，补而调之，若自利者，宜陈氏十二味异功散、肉以蔻丸主
之。盖病久气虚，惟利温补，不可再解毒也。
脓，是血液转化而成的产物。痘疮刚刚发出时，只是一点血珠，随后逐渐隆起、生长，由血化为浆液，再由浆液化为脓，这才形成实质性的脓疱。因此，有血就有脓，没有血也就没有脓。当痘疮发展到灌脓阶段，整体局势已经基本确定，此时必须以是否有脓为关键判断标准：有脓就能存活，无脓就会死亡，这是必然的道理。所以，在第六天之前，如果有发热症状，适宜使用解毒的方法；如果没有发热，则适宜调养气血，这样自然能够顺利灌脓。如果到了第七天以后，痘顶仍然凹陷不能灌脓的，一定是因为之前调理治疗不当所致，所以治疗不可拖延，必须等待浆液充足，才能挽回生命。如果痘顶凹陷且颜色灰白，浆液和脓液都无法生成，这说明气血已经离散，失去了生机。
一、痘疮灌脓的过程，专门以脾胃功能为核心。脾胃强健，则气血充实，形成的脓浆饱满、坚硬且浓稠，不需要额外服药；脾胃虚弱，则气血衰少，所以无法周身均匀灌脓，因此即使看到有浆液，浆液也不丰满，或者清淡灰白无法化脓，即便积蓄了少量浆液，也仍然是初期的血水。而浆液稀薄无法转化为脓的，总属于气血大虚的表现，如果不迅速治疗，必定会发展成内攻外溃的危重证候，应当紧急使用六物煎，或者对六气煎进行加减治疗，也可以使用保元汤，或者十全大补汤加入人乳、优质白酒一起服用，效果也很好。想要辨别脾胃的强弱，应当从饮食和二便情况来观察。虽然进食量少但大便干结的，说明脾胃之气尚可，只需轻微加以调补，以能正常进食为贵。如果大便不成形，或者出现溏泄，那就最为可怕。因为一旦腹泻，浆液就会停滞；腹泻停止后，灌脓才能充满。应当迅速使用温胃饮，病情严重的用陈氏十二味异功散为主方治疗。如果在应当化脓的时候，痘体仍然是空壳，这是血不依附于气的表现。血既已不至，毒素又从何化解？适宜使用五物煎，或者四物汤，或者紫草散加入蝉蜕为主方治疗。如果痘顶凹陷、脓液稀少，或者服用内托药物后暂时隆起又重新凹陷的，这是气血大虚的缘故，适宜使用十全大补汤，加倍加入人参、黄芪、当归、糯米，煎好后加入人乳、优质白酒服用，这是帮助灌脓的妙法。
一、在灌脓的三天之内，如果身体发凉且痘色灰白，或者不能进食，或者寒气上逆导致呕吐，或者腹胀，或者腹泻且手足逆冷，这些都是纯阴无阳的证候，应当紧急使用保元汤加入二仙散，连续服用几剂；病情严重的必须使用九味异功煎，或者陈氏十二味异功散，都可以选择使用。如果出现寒战、咬牙、腹泻等症状，都按照同样的方法治疗。
一、手足部位灌脓饱满的，才显示出脾胃强健、气血充足。如果颜色呈现灰白，浆液清稀淡薄，或者瘪陷不起的，这一定是脾胃虚弱所致。或者灌浆已经完成，但四肢仍有未灌满的地方，恐怕最终会变成瘙痒结痂的证候，适宜使用快斑越婢汤，或者在六气煎中加入防风、白芷以透达邪气，这样才能避免邪气陷伏的祸患。如果毒素未能完全透出，也担心在关节处，结痂后会产生痈毒。
一、瘙痒不止的情况，虽然说气血俱虚，但也由于火力不足，所以不疼痛而只瘙痒，适宜使用六气煎，或者五物煎加入防风、白芷、木香、蝉蜕为主方治疗。《心鉴》说：气越虚就越痒，应当使用保元汤加倍黄芪以助表气，少量加入芍药以制约血分，瘙痒自然停止。如果即将结痂时发生瘙痒，这是毒素消退、血液活跃、新肉生长顺畅的自然道理，不必治疗。
一、灌脓时疼痛不止的，是气机阻滞，稍微给予保元汤加入山楂、木香以行气滞。如果脓色盛满，大量使用四苓散利小便，疼痛自然停止。
一、痘疮起发之后，不化脓有四种证候：有因内部虚弱而不能灌脓的，专门适宜托补气血，治疗方法如前所述。有感受风寒，邪气停留在皮肤腠理而不能灌脓的，适宜温散，使用柴葛桂枝汤加入黄芪、白芷。有热毒炽盛、身体高热、津液干涸、小便赤热而不能灌脓的，适宜托里解毒并利小便，使用紫草饮子，或者使用辰砂六一散解除，等到热退后，才可以服用保元汤。热势严重的，使用大连翘饮。如果大便干结发热，数日不通畅而不能灌脓的，适宜用猪胆导泻，使气机疏通，那么营卫调和顺畅，否则恐怕会形成黑陷证。有触犯了秽浊之气而不能灌脓的，外部适宜熏蒸解表，使用胡荽酒，或者辟邪丹，内部服用紫草木香汤，或者紫草快斑汤。
程氏说：凡是痘顶凹陷没有脓液的属于逆证，但只要根部红润，血液尚未散失，紧急使用保元汤配合川芎、当归、白芍、丁香、糯米煎熟，加入人乳、优质白酒温服。如果颜色白如水晶，内部没有脓液，治疗方法也相同。只要有脓痘相间出现的还可以治疗，如果纯粹是水晶色的必定死亡。如果地面红赤、血液散失且有热的，去掉丁香，加入白芍、地骨皮以收敛血液、退热。如果出现寒战、咬牙，适宜选用木香散或异功散。
程氏说：凡是正气壮实的时候，虽然有痘疮起发壮实但皮肤无力，按压时水浆就流出，虽然肉色不暗，这被称为假壮，到了十一、二天绝对不能回浆结痂，会因内攻而死，可以紧急使用保元汤加入丁香、川芎、糯米，提气灌脓即可自愈。这就叫做内托法。凡是内托的方法，就是保元汤加入川芎、丁香即可，不必使用《千金方》中的内托方，只要按照本方辅助使用即可。
一、痘疮将要灌脓的时候，忽然面部出现干燥结痂的，就是倒陷证，应当迅速使用八珍汤或者六物煎加入金银花、牛蒡子、连翘、麻黄等药材，水煎熟，调服独圣散。服药后，如果干燥的重新隆起化脓，未干燥的就壮实饱满，或者在空缺处再长出补充空缺的小痘，这是最好的情况。如果痘疮不化脓，空缺处或发生痈毒的，情况次之。如果连续服用三剂后，干燥的不肿胀，未干燥的不饱满，补充的痘不多，那就是最危险的证候，适宜使用十全大补汤加入金银花调治。
一、灌脓时出现像弹丸大小的白色水泡，用枣针刺破排出水分，外部涂抹滑石粉，内部服用保元汤加入石榴皮、茯苓以利皮肤之水。如果发出紫色水泡，这是毒素溢出到皮肤表面，这个证候必定危险。
一、疮烂成片，脓水不干者，用滑石粉涂抹，或者使用收草散涂抹，加入珍珠粉尤其奇妙。
一、痘疮有重出的情况，凡是痘疮破损溃烂的地方，只要重新肿胀再次灌脓，不至于干枯，或者在原无痘的地方再次长出一层，如同初期起发灌脓的状态，这都是余毒未尽，依靠体内正气充实，毒素不得入内，所以仍然出于体表而不形成倒陷，这些都是逆证中的顺证。但是痘疮重出一次，必定要求患者能进食且大便干结，才足以承受再次发作的毒素，自然就没有可忧虑的了。如果吃得少且大便湿润的，适宜使用十全大补汤之类，补益并调理，如果是自发性腹泻的，适宜使用陈氏十二味异功散、肉豆蔻丸为主方治疗。因为病程久导致气虚，只有利于温补，不能再使用解毒药了。
Pus is a transformation of blood. When the smallpox rash first appears, it is merely a spot of blood; as it gradually rises and grows, it transforms from blood into serum (plasma), and then from serum into pus, thereby forming a solid pustule. Therefore, where there is blood, there is pus; where there is no blood, there is no pus. When the smallpox reaches the stage of filling with pus (Guannong), the general condition is already established. At this time, the presence or absence of pus is the primary criterion: life depends on the presence of pus, and death results from its absence; this is an inevitable principle. Thus, before the sixth day, if there is fever, detoxification is appropriate; if there is no fever, regulating Qi and Blood is appropriate, which will naturally lead to filling with pus. If, after the seventh day, the tops of the lesions remain depressed and fail to fill with pus, it must be due to prior improper regulation and treatment. Therefore, treatment cannot be delayed; one must wait for the serum to become sufficient to restore life. If the tops are depressed and grayish-white, with no serum or pus appearing, this indicates that both Qi and Blood have dispersed, and vitality is lost.
1. The process of smallpox filling with pus focuses primarily on the Spleen and Stomach. If the Spleen and Stomach are strong, Qi and Blood will be abundant, resulting in full, firm, and thick pus and serum, requiring no medication; if the Spleen and Stomach are weak, Qi and Blood will be deficient, leading to incomplete systemic filling. Thus, even if serum appears, it will not be full, or it may be clear, grayish-white, and unable to form pus. Even the small amount of accumulated serum remains merely initial blood-water. Serum that is too thin to transform into pus generally belongs to the pattern of severe deficiency of Qi and Blood. If not treated promptly, it will inevitably develop into internal attack and external ulceration syndromes. One should urgently use Liuwu Decoction (Six-Ingredient Decoction), or modify Liuqi Decoction (Six-Qi Decoction). Alternatively, Baoyuan Decoction (Preserve the Origin Decoction) or Shiquan Dabu Tang (Ten Complete Great Tonifying Decoction) added with human milk and good wine can be taken, which is also excellent. To distinguish the strength of the Spleen and Stomach, observe diet and bowel movements. Although food intake may be low, if stools are hard, the Qi of the Spleen and Stomach is still acceptable; slight tonification and regulation are needed, prioritizing the ability to eat. If stools are loose or diarrhea occurs, this is most alarming. For once diarrhea starts, serum formation stops; once diarrhea ceases, filling resumes. Urgently use Wenwei Yin (Warm the Stomach Infusion); for severe cases, use Chen's Twelve-Ingredient Yigong San (Extraordinary Efficacy Powder) as the main formula. If at the time when pus should form, the lesion remains an empty shell, this indicates Blood failing to adhere to Qi. Since Blood has not arrived, how can toxins be transformed? Use Wuwu Jian (Five-Material Decoction), or Siwu Tang (Four-Substance Decoction), or Zicao San (Arnebiae Herb Powder) added with Cicada Slough (Chantui). If the tops are depressed with little pus, or if they temporarily rise after taking internal-supporting medicines but then sink again, this is due to severe deficiency of Qi and Blood. Use Shiquan Dabu Tang (Ten Complete Great Tonifying Decoction) with increased doses of Ginseng Radix (Renshen), Astragali Radix (Huangqi), Angelicae Sinensis Radix (Danggui), and Glutinous Rice (Nuomi). After decocting, add human milk and good wine for administration; this is a wonderful method to assist filling.
1. Within the three days of filling with pus, if the body is cool and the rash color is grayish-white, or if the patient cannot eat, or if cold Qi rebels upward causing vomiting, or abdominal distension, or diarrhea with cold extremities, these are all patterns of pure Yin without Yang. Urgently use Baoyuan Decoction (Preserve the Origin Decoction) added with Erxian San (Two-Immortal Powder), administered continuously for several doses; for severe cases, Jiawei Yigong Jian (Nine-Ingredient Extraordinary Efficacy Decoction) or Chen's Twelve-Ingredient Yigong San (Extraordinary Efficacy Powder) can be selected. Symptoms such as chills, teeth grinding, and diarrhea are treated similarly.
1. Full filling of pus in the hands and feet indicates strong Spleen and Stomach and sufficient Qi and Blood. If the color is grayish-white, the serum is clear and thin, or the lesions are sunken and do not rise, this is due to weak Spleen and Stomach. Or, if filling is complete but some limbs remain unfilled, fear that it may eventually turn into an itching and crusting syndrome. Use Kuaiban Yu Pi Tang (Rapid Rash Dispersing Cough Suppression Decoction), or Liuqi Decoction (Six-Qi Decoction) added with Saposhnikoviae Radix (Fangfeng) and Angelicae Dahuricae Radix (Baizhi) to vent the pathogen, thus avoiding the risk of pathogen sinking inward. If toxins are not fully expelled, fear that abscesses may form at the joints after crusting.
1. Persistent itching, although attributed to deficiency of both Qi and Blood, is also due to insufficient Fire/Heat energy, hence causing itching rather than pain. Use Liuqi Decoction (Six-Qi Decoction), or Wuwu Jian (Five-Material Decoction) added with Saposhnikoviae Radix (Fangfeng), Angelicae Dahuricae Radix (Baizhi), Aucklandiae Radix (Muxiang), and Cicada Slough (Chantui) as the main formula. *Xinjian* states: "The more deficient the Qi, the more intense the itching." Use Baoyuan Decoction (Preserve the Origin Decoction) with doubled Astragali Radix (Huangqi) to support the exterior, and add a small amount of Paeoniae Radix Alba (Shaoyao) to regulate Blood; the itching will cease naturally. If itching occurs just before crusting, this is because toxins are receding, Blood is active, and new flesh is growing smoothly; this is a natural phenomenon and requires no treatment.
1. Unceasing pain during filling indicates Qi stagnation. Administer Baoyuan Decoction (Preserve the Origin Decoction) with Hawthorn Fruit (Shanzha) and Aucklandiae Radix (Muxiang) to move stagnant Qi. If the pus is abundant and full, administer Sizheng San (Four-Zheng Powder) in large doses to promote urination, and the pain will cease.
1. After the eruption of smallpox, failure to form pus presents four patterns:
- Internal deficiency preventing filling: Primarily suitable for supporting and tonifying Qi and Blood, using methods as described above.
- Wind-Cold invasion, with pathogens residing in the skin and interstices preventing filling: Suitable for warming and dispersing, using Chai Ge Gui Zhi Tang (Bupleuri and Kudzu and Cinnamon Twig Decoction) added with Astragali Radix (Huangqi) and Angelicae Dahuricae Radix (Baizhi).
- Excessive Heat-Toxin causing high fever, dry fluids, red hot urine, and preventing filling: Suitable for supporting the interior, clearing toxins, and promoting urination, using Zicao Yinzi (Arnebiae Drink) or Chen Sha Liu Yi San (Cinnabar Six-to-One Powder) to resolve it. Only after the heat subsides should Baoyuan Decoction (Preserve the Origin Decoction) be used. For severe heat, use Da Lian Qiao Yin (Large Forsythia Drink).
- Hard, hot stools, unpassed for several days, preventing filling: Suitable for using Pig Gallbladder (Zhudan) for enema to unblock Qi flow, so that Ying and Wei Qi harmonize and flow smoothly; otherwise, black depression syndrome may result.
- Contact with foul miasma preventing filling: External fumigation with Hu Su Jiu (Coriander Wine) or Pixie Dan (Evil-Dispelling Pill); internally take Zicao Muxiang Tang (Arnebiae and Aucklandia Decoction) or Zicao Kuaiban Tang (Arnebiae Rapid Rash Dispersing Decoction).
Master Cheng said: "Any case with depressed tops and no pus is a reverse syndrome. However, if the root base is ruddy and Blood has not scattered, urgently use Baoyuan Decoction (Preserve the Origin Decoction) combined with Chuanxiong Rhizome (Chuanxiong), Angelicae Sinensis Radix (Danggui), White Peony Root (Baishao), Clove Flower (Dingxiang), and Glutinous Rice (Nuomi). Decoct until ripe, add human milk and good wine, and take warm. If the color is white like crystal with no internal pus, the treatment is the same. As long as there are mixed pus-filled and non-pus lesions, it is treatable; if purely crystal-colored, death is certain. If the base is red with scattered Blood and heat, remove Dingxiang (Clove), add Baishao (White Peony Root) and Cortex Lycii (Digupi) to astringe Blood and reduce heat. If chills and teeth grinding occur, select Muxiang San (Aucklandia Powder) or Yigong San (Efficacy Powder)."
Master Cheng said: "During the vigorous stage, if smallpox erupts vigorously but the skin lacks strength, and pressing causes serum to exude, although the flesh color is not dark, this is called 'False Vigor'. By the 11th or 12th day, it will definitely fail to return serum and crust, leading to death from internal attack. Urgently use Baoyuan Decoction (Preserve the Origin Decoction) added with Dingxiang (Clove), Chuanxiong Rhizome (Chuanxiong), and Nuomi (Glutinous Rice) to raise Qi and fill with pus, leading to self-healing. This is called the 'Internal Support' method. The method of Internal Support is simply Baoyuan Decoction (Preserve the Origin Decoction) added with Chuanxiong Rhizome (Chuanxiong) and Dingxiang (Clove); there is no need to use the Internal Support formula from *Qianjin Fang*, but rather use it as an adjuvant to the base formula."
1. Just as smallpox is about to fill with pus, if dry crusts suddenly appear on the face, this is the "Reverse Depression" syndrome. Urgently use Bazhen Tang (Eight-Treasure Decoction) or Liuwu Jian (Six-Material Decoction) added with Honeysuckle Flower (Jinyinhua), Burdock Fruit (Niubangzi), Forsythia Fruit (Lianqiao), and Ephedra Stem (Mahuang). Decoct in water, and take with Dusheng San (Single-Sage Powder). After medication, if dry areas rise again to form pus, and non-dry areas become vigorous and full, or if supplementary small pox appear in empty spaces to fill them, this is the best outcome. If smallpox fails to form pus, and abscesses develop in empty spaces, this is a secondary outcome. If after three doses, dry areas do not swell, non-dry areas do not become full, and few supplementary pox appear, this is the most critical syndrome. Use Shiquan Dabu Tang (Ten Complete Great Tonifying Decoction) added with Jinyinhua (Honeysuckle Flower) for treatment.
1. If bubble-like white blisters the size of a bullet appear during filling, puncture them with a jujube thorn to drain the fluid, apply Talcum Powder (Huashi Mo) externally, and internally take Baoyuan Decoction (Preserve the Origin Decoction) added with Pomegranate Rind (Shiliupi) and Poria (Fuling) to drain fluid from the skin. If purple blisters appear, this indicates toxins overflowing onto the skin surface; this syndrome is critical.
1. For ulcers rotting in patches with non-drying pus/water, apply Talcum Powder (Huashi Mo) or Shoucao San (Gathering Grass Powder); adding Pearl Powder (Zhenzhu) is especially excellent.
1. Regarding recurrent smallpox: In areas where smallpox has broken down and ulcerated, if they swell again and refill with pus without drying out, or if a new layer erupts in originally unaffected areas, resembling the initial eruption and filling stages, this is due to residual toxins not yet exhausted. Relying on substantial interior Qi, the toxins cannot enter inwardly, so they remain on the exterior without causing reverse depression. These are favorable developments within adverse conditions. However, for smallpox to recur, the patient must be able to eat and have hard stools to withstand the renewed toxin attack, eliminating concern. If appetite is poor and stools are moist, use Shiquan Dabu Tang (Ten Complete Great Tonifying Decoction) etc. to tonify and regulate. If spontaneous diarrhea occurs, use Chen's Twelve-Ingredient Yigong San (Extraordinary Efficacy Powder) or Rou Doukou Wan (Nutmeg Pill) as the main formula. Because prolonged illness leads to Qi deficiency, only warming and tonifying are beneficial; detoxification should not be used again.