（宋《开宝》）
【释名】信石、人言（《纲目》），生者名砒黄，炼者名砒霜。
时珍曰∶砒，性猛如貔，故名。惟出信州，故人呼为信石，而又隐信字为人言。
【集解】颂曰∶砒霜不着所出郡县，今近铜山处亦有之，惟信州者佳。其块有甚大者，
色如鹅子黄，明澈不杂。此类本处自是难得之物，一两大块真者，人竞珍之，不啻千金。古
服食方中亦载用之，必得此类，乃可入药。其市肆所畜片如细屑，亦夹土石，入药服之，为
害不浅。
承曰∶信州玉山有砒井，官中封禁甚严。生不夹石者，色赤甚于雄黄，以冷水磨，解热
毒，近火即杀人，所谓不啻金价者此也。今市货者，取山中夹砂石者，烧烟飞作白霜，乃碎
屑而芒刺。其伤火多者，块大而微黄，所谓如鹅子色明澈者，此也。古方并不入药，惟烧炼
丹石家用之。近人多以治疟，但以疟本伤暑，而此物生者能解热毒也。今俗医不究其理，即
以所烧霜服之，必大吐下，因此幸有安者，遂为定法，尔后所损极多，不可不慎。初烧霜时，
人在上风十余丈外立，下风所近草木皆死；又以和饭毒鼠，死鼠，猫犬食之亦死，毒过于射
罔远矣。衡山所出一种，力差劣于信州者。
宗 曰∶今信凿坑井下取之。其坑常封锁。坑中有浊绿水，先绞水尽，然后下凿取。生
砒谓之砒黄，色如牛肉，或有淡白路，谓石非石，谓土非土。磨酒饮，治癖积气。有火便有
毒，不可造次服也。取法∶将生砒就置火上，以器覆之，令烟上飞，着器凝结。累然下垂如
乳尖者入药为胜，平短者次之，大块乃是下等片，如细屑者极下也。
时珍曰∶此乃锡之苗，故新锡器盛酒日久能杀人者，为有砒毒也。生砒黄以赤色者为良
，熟砒霜以白色者为良。
【修治】 曰∶凡使用，以小瓷瓶盛，后入紫背天葵、石龙芮二味，火 ，从巳至申；
便用甘草水浸，从申至子，出拭干，入瓶再 ，别研三万下用。
时珍曰∶医家皆言生砒轻见火则毒甚，而雷氏治法用火 ，今所用多是飞炼者，盖皆欲
求速效，不惜其毒也，曷若用生者为愈乎？
【气味】苦、酸，暖，有毒。时珍曰∶辛、酸，大热，有大毒。
大明曰∶畏绿豆、冷水、醋。入药，醋煮杀毒用。
土宿真君曰∶砒石用草制，炼出金花，成汁化铜干汞。青盐、鹤顶草、硝石、蒜、水蓼
、常山、益母、独帚、木律、菖蒲、三角酸、鹅不食草、菠菱、莴苣，皆能伏砒。
【主治】砒黄∶治疟疾肾气，带之辟蚤虱（大明）。冷水磨服，解热毒，治痰壅（陈承）。
磨服，治癖积气（宗 ）。除 喘积痢，烂肉，蚀瘀腐瘰 （时珍）。砒霜∶疗诸疟，风痰在
胸
膈，可作吐药。不可久服，伤人（《开宝》）。治妇人血气冲心痛，落胎（大明）。蚀痈疽败肉，
枯痔杀虫，杀人及禽兽（时珍）。
【发明】宗 曰∶砒霜疟家用，或过剂，则吐泻兼作，须煎绿豆汁兼冷水饮之。
刘纯曰∶疟丹多用砒霜大毒之药。本草谓主诸疟风痰在胸膈，可作吐药。盖以性之至烈，
大能燥痰也。虽有燥痰之功，大伤胸气，脾胃虚者，切宜戒之。
时珍曰∶砒乃大热大毒之药，而砒霜之毒尤烈。鼠雀食少许，即死；猫犬食鼠雀亦殆；
人服至一钱许，亦死。虽钩吻、射罔之力，不过如此，而宋人着本草不甚言其毒，何哉？此
亦古者 石之一种也，若得酒及烧酒，则腐烂肠胃，顷刻杀人，虽绿豆、冷水亦难解矣。
今之收瓶酒者，往往以砒烟熏瓶，则酒不坏，其亦嗜利不仁者哉？饮酒潜受其毒者，徒
归咎于酒耳。此物不入汤饮，惟入丹丸。凡痰疟及 喘用此，真有劫病立地之效。但须冷水
吞之，不可饮食杯勺之物，静卧一日或一夜，亦不作吐；少物引发，即作吐也。其燥烈纯热
之性，与烧酒、焰硝同气，寒疾湿痰被其劫而怫郁顿开故也。今烟火家用少许，则爆声更大，
急烈之性可知矣。此药亦只宜于山野藜藿之人。若嗜酒膏粱者，非其所宜，疾亦再作，不慎
口欲故尔。凡头疮及诸疮见血者，不可用，此其毒入经必杀人。李楼《奇方》云∶一妇病心
痛数年不愈。一医用人言半分，茶末一分，白汤调下，吐瘀血一块而愈。得《日华子》治妇
人血气心痛之旨乎？
【附方】旧五，新十。
中风痰壅，四肢不收，昏愦若醉。砒霜如绿豆大，研。新汲水调下少许，以热水投之，
大吐即愈。未吐再服。（《圣惠方》）
寒热 疾∶孙真宗《秘宝方》∶用信砒二两（研粉），寒水石三两（别捣末）。用生铁铫
一
个，铺石末，后铺砒在上，又以石末盖之。浓盏覆定，醋糊纸条密封十余重，炭火一斤 之。
待纸条黑时取出，候冷，刮盏上砒末乳细，粟米饭丸绿豆大，辰砂为衣。每用三、四丸，
小儿一、二丸，发日早以腊茶清下，一日不得食热物。
男人患，女人着药入口中；女人患，男人着药入口中。《本事方》∶用人言一钱，绿豆末
一两，为末，无根井水丸绿豆大，黄丹为衣，阴干。发日五更冷水下五、七丸。《卫生宝鉴》
一剪金∶用人言（醋煮）、硫黄、绿豆等分。为末。每一豆许，用红绢包之，采丝扎定。每
剪
下一粒，新汲水空心吞下，治疟圣药也。《医垒元戎》九转灵砂丹∶用砒霜、黄丹、紫河车
各一钱。为末，雄黑豆一百粒，水浸一夜，研泥，和丸梧子、绿豆、黍米三样大，量虚实老
幼大小服之。每服一、二丸或三丸，不发日五更向东无根水下。紫河车、绿豆、黑豆，皆解
砒毒也。《本草权度》不二散∶用砒一钱，面二两，和匀，香油一斤煎黄色，以草纸压去油，
入茶三两，为末。每服一钱，发日早冷茶下。
一切积痢∶砒霜、黄丹等分。蜡和收，旋丸绿豆大。每米饮下三丸。（《普济方》）
休息下痢，经一、二年不瘥，羸瘦衰弱。砒霜（成块者为末）、黄蜡各半两。化蜡入砒，
以柳条搅，焦则换，至七条，取起收之。每旋丸梧子大，冷水送下。小儿，黍米大。（《和
剂局方》）
脾疼腰痛∶即上方，用冷水下。
妇人血气心痛∶方见发明下。
走马牙疳恶疮∶砒石、铜绿等分。为末。摊纸上贴之，其效如神。又方∶砒霜半两。醋
调如糊，碗内盛，待干刮下。用粟米大，绵裹安齿缝，来日取出，有虫自死。久患者，不过
三日即愈。（《普济方》）
项上瘰 ∶信州砒黄研末，浓墨汁丸梧子大，铫内炒干，竹筒盛之。每用针破，将药半
丸贴之，自落，蚀尽为度。（《灵苑方》）痰喘 ∶方见谷部，豉下。
一切漏疮有孔∶用信石，新瓦火 ，研末。以津调少许于纸捻上，插入，蚀去恶管，漏
多，勿齐上。最妙。（《急救良方》）
（宋代《开宝本草》记载）
【释名】信石、人言（《本草纲目》），未经炼制的称为砒黄，经过炼制的称为砒霜。
李时珍说：砒的性情猛烈如同貔兽，所以得名。只产于信州，所以人们称它为信石，又隐去“信”字称为人言。
【集解】苏颂说：砒霜不注明出产的郡县，现在靠近铜山的地方也有出产，只有信州的品质最佳。其块状物有非常大的，颜色像鹅子黄一样，明亮清澈且不混杂。这类东西在当地本是难得之物，一两重的真品大块，人们竞相珍视，价值不止千金。古代服食方中也有记载使用它，必须得到这类药材，才可以入药。市场上出售的片状如细屑者，也夹杂着土石，入药服用，危害不小。
陈承说：信州玉山县有砒井，官府封禁非常严格。未夹杂石头的生砒，颜色比雄黄更红，用冷水研磨，可以解除热毒，靠近火就会致人死亡，这就是所谓价值超过金价的原因。现在的市售货品，是取山中夹杂砂石的东西，烧烟飞散成白霜，成为碎屑且有芒刺。其中受火气多的大块且微黄的，就是所谓像鹅子色那样明澈的，这是指此类。古方并不入药，只有烧炼丹石的人家使用。近来很多人用它治疗疟疾，但因为疟疾本是由于伤暑所致，而生砒能解除热毒，所以有人使用。现在的庸医不探究其中的道理，就直接将烧制后的霜服用，必然导致剧烈吐泻，因此侥幸痊愈的人，就被定为常规方法，此后受损的人极多，不可不谨慎。刚烧制出霜时，人在上风处十几丈外站立，下风处的草木都会枯死；又用拌饭毒鼠，老鼠死后，猫狗吃了也会死亡，毒性远超过射罔。衡山出产的一种，效力比信州的差一些。
寇宗奭说：现在信州凿坑井下开采。这些坑经常封锁。坑中有浑浊的绿水，先绞干水，然后下去开采。生砒称为砒黄，颜色像牛肉，或者有淡白色的纹路，说是石头不像石头，说是泥土不像泥土。磨酒饮用，可以治疗癖积气。有火就有毒，不可随意服用。采集方法：将生砒放在火上，用器皿覆盖，让烟上升，附着在器皿上凝结。堆积下垂像乳尖形状的最好入药，平短的次之，大块的是下等品，如细屑的最为低劣。
李时珍说：这是锡的苗裔，所以新锡器盛放酒日久能杀人的原因，是因为含有砒毒。生砒黄以赤色者为优良，熟砒霜以白色者为优良。
【修治】雷敩说：凡是用砒，用小瓷瓶盛装，后加入紫背天葵、石龙芮两味药，用火煅烧，从巳时到申时；然后用甘草水浸泡，从申时到子时，取出擦干，装入瓶中再次煅烧，另外研磨三万次后使用。
李时珍说：医家都说生砒稍微见火则毒性更甚，而雷敩的治疗方法是用火煅烧，现在使用的多是飞炼过的，大概都是想求速效，不惜其毒性，不如使用生者更好呢？
【气味】苦、酸，暖，有毒。李时珍说：辛、酸，大热，有大毒。
唐慎微（大明）说：畏绿豆、冷水、醋。入药时，用醋煮以杀灭毒性。
土宿真君说：砒石用草制法炼制，可炼出金花，使铜和干汞熔化。青盐、鹤顶草、硝石、蒜、水蓼、常山、益母草、独帚、木律、菖蒲、三角酸、鹅不食草、菠菱、莴苣，都能制约砒。
【主治】砒黄：治疗疟疾肾气，佩戴它可以避蚤虱（唐慎微）。用冷水磨服，解除热毒，治疗痰壅（陈承）。磨服，治疗癖积气（寇宗奭）。去除冷喘、积痢，烂肉，腐蚀瘀腐瘰疬（李时珍）。砒霜：治疗各种疟疾，胸膈间的风痰，可作为催吐药。不可久服，伤人（《开宝本草》）。治疗妇人血气冲心痛，堕胎（唐慎微）。腐蚀痈疽败肉，枯痔杀虫，杀人及禽兽（李时珍）。
【发明】寇宗奭说：砒霜被疟疾医生使用，如果过量，就会吐泻并作，需要煎绿豆汁兼冷水饮用来解毒。
刘纯说：治疟丹多用砒霜这种大毒之药。本草说主治各种疟疾风痰在胸膈，可作为吐药。这是因为其性质极其猛烈，大能燥痰。虽然有燥痰的功效，但大伤胸气，脾胃虚弱的人，务必戒除。
李时珍说：砒是大热大毒之药，而砒霜的毒性尤其猛烈。老鼠麻雀吃少许，即死；猫狗吃了鼠雀也有危险；人服用至一钱左右，也会死。虽然钩吻、射罔的力量，也不过如此，但宋代人著述本草不太强调其毒性，为什么呢？这也是古代丹石类药物的一种，如果遇到酒及烧酒，就会腐烂肠胃，顷刻杀人，即使是绿豆、冷水也难以解救。现在收存酒瓶的人，往往用砒烟熏瓶子，这样酒就不会坏，这真是贪利不仁的人啊！饮酒暗中受到其毒害的人，只是归咎于酒罢了。此物不入汤剂饮片，只入丹丸。凡是痰疟及冷喘使用此药，真有劫病立竿见影的效果。但须用冷水吞服，不可饮食杯勺之物，静卧一天或一夜，也不会呕吐；少量引发，就会呕吐。其燥烈纯热的性质，与烧酒、焰硝同气，寒疾湿痰被其劫持而郁结顿开的原因。现在烟火家用少许，爆炸声更大，急烈的性质可知了。此药也只适合山野粗茶淡饭之人。如果嗜好酒肉的人，不适合使用，疾病也会复发，这是不慎口欲的缘故。凡是头疮及诸疮见血的，不可用，此毒入经必杀人。李楼《奇方》说：一个妇人患心痛数年不愈。一位医生用人言半分，茶末一分，白开水调下，吐出瘀血一块而痊愈。得到了《日华子》治疗妇人血气心痛的宗旨吗？
【附方】旧方五首，新方十首。
中风痰壅，四肢不能收引，昏愦如醉。砒霜如绿豆大小，研细。新汲水调下少许，用热水送服，大吐即愈。未吐再服。（《圣惠方》）
寒热疟疾：孙真宗《秘宝方》：用信砒二两（研粉），寒水石三两（另捣末）。用一个生铁铫，铺上石末，后铺砒在上，又以石末盖之。用浓盏覆盖定，醋糊纸条密封十余重，炭火一斤煅烧。待纸条变黑时取出，候冷，刮下盏上砒末研细，粟米饭丸如绿豆大，朱砂为衣。每次用三、四丸，小儿一、二丸，发作日早晨用腊茶清送下，一天内不得吃热物。
男人患疟，女人含药入口中；女人患疟，男人含药入口中。《本事方》：用人言一钱，绿豆末一两，为末，无根井水丸如绿豆大，黄丹为衣，阴干。发作日五更用冷水送下五、七丸。《卫生宝鉴》一剪金：用人言（醋煮）、硫黄、绿豆等分。为末。每一豆许，用红绢包之，采丝扎定。每剪下一粒，新汲水空心吞下，是治疟圣药。《医垒元戎》九转灵砂丹：用砒霜、黄丹、紫河车各一钱。为末，雄黑豆一百粒，水浸一夜，研泥，和丸梧子、绿豆、黍米三样大，量虚实老幼大小服之。每次服一、二丸或三丸，不发日五更向东无根水下。紫河车、绿豆、黑豆，都能解砒毒。《本草权度》不二散：用砒一钱，面二两，和匀，香油一斤煎黄色，以草纸压去油，入茶三两，为末。每次服一钱，发作日早晨冷茶送下。
一切积痢：砒霜、黄丹等分。蜡和收，随时丸如绿豆大。每次米饮送下三丸。（《普济方》）
休息下痢，经过一、二年不愈，身体消瘦衰弱。砒霜（成块的研为末）、黄蜡各半两。化蜡入砒，用柳条搅拌，焦了就换，直到七条，取起收之。每次随时丸如梧子大，冷水送下。小儿，丸如黍米大。（《和剂局方》）
脾疼腰痛：即上方，用冷水送下。
妇人血气心痛：方见发明下。
走马牙疳恶疮：砒石、铜绿等分。为末。摊纸上贴之，其效如神。又方：砒霜半两。醋调如糊，碗内盛，待干刮下。用粟米大，绵裹安齿缝，来日取出，有虫自死。久患者，不过三日即愈。（《普济方》）
项上瘰疬：信州砒黄研末，浓墨汁丸如梧子大，铫内炒干，竹筒盛之。每次用针破，将药半丸贴之，自落，腐蚀尽为止。（《灵苑方》）痰喘：方见谷部，豉下。
一切漏疮有孔：用信石，新瓦火煅，研末。以津液调少许于纸捻上，插入，腐蚀去恶管，漏多，勿齐上。最妙。（《急救良方》）
(Song Dynasty *Kaibao Bencao*)
[Names] Xinshi (Cinnabar Stone), Renyan (Human Speech) (*Bencao Gangmu*). The raw form is called Pi Huang (Arsenic Yellow), and the refined form is called Pi Shuang (Arsenic Frost).
Li Shizhen stated: "Pi" derives its name from its fierce nature, resembling the Pi beast. It is only produced in Xin Zhou, hence people call it Xin Shi (Xin Stone), and by hiding the character "Xin," it is referred to as Renyan (Human Speech).
[Collection and Explanation] Su Song stated: The origin of Pi Shuang (Arsenic Frost) is not recorded in specific commanderies or counties. Currently, it is also found near Tong Shan, but those from Xin Zhou are of the best quality. The lumps can be very large, with a color like goose egg yolk, bright, clear, and unadulterated. This type of substance is rare locally; a true lump weighing one liang is highly prized by people, worth more than a thousand gold pieces. Ancient prescription for longevity also records its use, requiring this specific type for medicinal application. The flakes sold in markets, which resemble fine dust, often contain earth and stones; using them medicinally causes significant harm.
Chen Cheng stated: There are arsenic wells in Yushan County, Xin Zhou, which are strictly sealed by the government. Raw arsenic free from stone impurities is redder than realgar. When ground with cold water, it resolves heat toxicity; approaching fire causes death, which explains why it is said to be worth more than gold. Current market goods are obtained by burning arsenic-bearing sandstone from mountains, causing smoke to fly and condense into white frost, forming fragments with sharp edges. Those with high fire exposure form large, slightly yellow blocks, described as clear like goose egg yolk. Ancient prescriptions did not use it medicinally; only alchemists used it for refining cinnabar and stones. Recently, many people use it to treat malaria. Since malaria originates from summerheat injury, and raw arsenic can resolve heat toxicity, some employ it. However, contemporary quacks fail to investigate the principles and directly administer the refined frost, inevitably causing severe vomiting and purging. Due to occasional lucky recoveries, this became a standard method, resulting in numerous subsequent injuries. One must exercise extreme caution. During initial smelting, standing ten zhang upwind causes vegetation downwind to die. Poisoned rice bait kills rats; if cats or dogs eat these dead rats, they also die. Its toxicity far exceeds that of She Wang (Aconite poison). A variety from Heng Shan is inferior in potency to that from Xin Zhou.
Kou Zongshi stated: Currently, Xin Zhou mines arsenic from sealed pits containing turbid green water. The water is first wrung out before descent. Raw arsenic is called Pi Huang, colored like beef flesh, sometimes with pale white veins. It is neither stone nor soil. Ground in wine and drunk, it treats fixed masses and qi stagnation. Fire implies toxicity; it must not be taken casually. Collection method: Place raw arsenic on fire, cover with a vessel to collect ascending smoke condensate. Dripping forms resembling teats are superior for medicine; flat/short ones are secondary; large chunks are inferior; fine dust is the lowest grade.
Li Shizhen stated: This is the "seed" of tin. Hence, new tin vessels holding wine for long periods can be lethal due to arsenic toxicity. For raw Pi Huang, red is superior; for refined Pi Shuang, white is superior.
[Processing] Lei Xiao stated: For use, store in a small porcelain bottle. Add Zi Bei Tian Kui (Ophiopogon japonicus var. bulbifer? *Note: Traditionally interpreted as specific herbs for processing, here kept as proper noun*) and Shi Long Rui (Batrachium scabrum). Calcine from Si hour to Shen hour. Then soak in Licorice root water from Shen hour to Zi hour. Remove, dry, place back in bottle, calcine again, and grind thirty thousand times before use.
Li Shizhen stated: Physicians claim raw arsenic becomes extremely toxic upon slight heating. However, Lei Xiao’s method uses fire calcination. Most current usage involves sublimated arsenic, likely seeking rapid effects regardless of toxicity. Is it not better to use the raw form?
[Flavor and Toxicity] Bitter, sour, warm, toxic. Li Shizhen stated: Pungent, sour, extremely hot, highly toxic.
Tang Shenwei stated: Feared by Mung bean, cold water, and vinegar. In medicine, boil with vinegar to neutralize toxicity.
Tu Su Zhen Jun stated: Arsenic processed with herbs can yield golden flowers and melt copper and quicksilver. Green salt, Crane Top Grass, Niter, Garlic, Water Pepper, Oldenlandia, Motherwort, Du Zhou, Mu Lv, Acorus, Triangle Acid, Elephant's Foot Herb, Spinach, Lettuce can all suppress arsenic.
[Indications] Pi Huang: Treats malaria affecting kidney qi; wearing it repels fleas and lice (Tang Shenwei). Ground with cold water and taken, it resolves heat toxicity and treats phlegm obstruction (Chen Cheng). Ground and taken, it treats fixed masses and qi stagnation (Kou Zongshi). Removes cold asthma, accumulated dysentery, putrefies flesh, and corrodes stagnant腐 tissue and scrofula (Li Shizhen). Pi Shuang: Treats various malarial fevers, wind-phlegm in chest/diaphragm; can be used as an emetic. Do not take long-term as it harms the body (*Kaibao Bencao*). Treats women’s blood/qi rushing heart pain; induces abortion (Tang Shenwei). Corrodes carbuncle ulcers and necrotic flesh; dries hemorrhoids and kills parasites; lethal to humans and animals (Li Shizhen).
[Elucidation] Kou Zongshi stated: When physicians use Pi Shuang for malaria, overdose causes simultaneous vomiting and diarrhea. One must decoct Mung bean juice mixed with cold water to antidote.
Liu Chun stated: Malaria pills often use Pi Shuang, a highly toxic drug. Materia Medica states it treats wind-phlegm in chest/diaphragm as an emetic because its nature is extremely fierce and strongly dries phlegm. While effective at drying phlegm, it severely damages chest qi. Those with weak spleen/stomach must strictly avoid it.
Li Shizhen stated: Arsenic is extremely hot and highly toxic; Pi Shuang is particularly potent. Rats and birds die from a tiny amount; cats/dogs eating poisoned rodents are endangered; humans die from approximately one qian. Although Gou Wen (Gelsemium) and She Wang have similar lethality, Song dynasty pharmacopoeias understated its toxicity. Why? It is a type of ancient mineral drug. If ingested with wine or distilled spirits, it rots the intestines/stomach, killing instantly; even Mung beans and cold water cannot save the victim. Some wine merchants fumigate bottles with arsenic smoke to prevent spoilage, acting greedily and ruthlessly. Drinkers unknowingly absorb the toxin and blame the wine. This substance is not used in decoctions, only in pills. For phlegmatic malaria and cold asthma, it has immediate, drastic efficacy. Swallow with cold water without food/drink; rest quietly for a day or night to avoid vomiting. Small amounts induce vomiting. Its pure hot nature aligns with distilled spirits and saltpeter; it forcibly opens blockages in cold-dampness and phlegm. Pyrotechnicians use small amounts for louder explosions, demonstrating its violent nature. This drug suits only rugged, rural individuals. Those indulging in rich foods/alcohol should not use it, lest disease recur due to dietary indiscretion. Do not use on head sores or bleeding wounds; toxin entering meridians is fatal. Li Lou’s *Qi Fang* records: A woman suffered heart pain for years. A physician administered half a fen of Renyan and one fen of tea powder with warm water. She vomited a clot of stagnant blood and was cured. This aligns with *Ri Hua Zi*’s principle for treating women’s blood/qi heart pain.
[Attached Prescriptions] Five old, ten new.
Stroke with phlegm obstruction, limbs flaccid, confusion like drunkenness: Grind Pi Shuang to size of mung beans. Mix with fresh well water, take a small amount, follow with hot water. Profuse vomiting leads to cure. Repeat if no vomiting occurs. (*Shenghui Fang*)
Cold-heat malaria: Sun Zhenzong’s *Mibao Fang*: Use 2 liang Xin Pi (powdered), 3 liang Han Shui Shi (cold water stone, powdered separately). In a cast iron pot, layer stone powder, then arsenic, then cover with stone powder. Seal tightly with vinegar-paste paper strips (over ten layers). Cover with a thick cup. Calcine with 1 jin charcoal until paper turns black. Remove, cool, scrape arsenic powder, grind fine, mix with millet paste to make pills size of mung beans. Coat with Cinnabar. Take 3-4 pills (1-2 for children) early on attack day with aged tea liquor. Avoid hot food for one day.
For male malaria patients, female holds pill in mouth; for female patients, male holds pill in mouth. (*Benshi Fang*): 1 qian Renyan, 1 liang Mung bean powder. Mix, pellet with well water (no root water), coat with Red Lead. Dry in shade. Take 5-7 pills at dawn on attack day with cold water. (*Weisheng Baojian*) Yi Jian Jin: Equal parts Renyan (vinegar-boiled), Sulfur, Mung bean. Powder. Wrap bean-sized amount in red silk, tie with thread. Cut off one grain, swallow empty stomach with fresh water. Holy medicine for malaria. (*Yilei Yuanrong*) Jiu Zhuan Ling Sha Dan: 1 qian each of Pi Shuang, Red Lead, Placenta (Zi He Che). Powder. Soak 100 Black Soybeans overnight, grind to paste, mix with powders. Make pills size of wu zi, mung beans, or millet grains. Dosage based on age/condition. Take 1-3 pills at dawn on non-attack days facing east with rootless water. Placenta, Mung bean, Black soybean all detoxify arsenic. (*Bencao Quandu*) Bu Er San: 1 qian Arsenic, 2 liang Flour. Mix. Fry in 1 jin Sesame oil until yellow. Press oil out with grass paper. Add 3 liang Tea. Powder. Take 1 qian early on attack day with cold tea.
All types of accumulated dysentery: Equal parts Pi Shuang, Red Lead. Mix with wax, pellet size of mung beans. Take 3 pills with rice drink. (*Pujifang*)
Relapsing dysentery lasting 1-2 years, emaciated and weak: 0.5 liang Pi Shuang (lump form powdered), 0.5 liang Yellow Wax. Melt wax, add arsenic, stir with willow twig. Replace twig when charred, repeat seven times. Collect. Pellet size of wu zi (children: millet size). Take with cold water. (*Heji Jufang*)
Spleen/Lower back pain: Same formula above, take with cold water.
Women’s blood/qi heart pain: See Elucidation section.
Rapid gangrenous stomatitis/malignant sores: Equal parts Arsenic stone, Verdigris. Powder. Spread on paper and apply. Effect miraculous. Another method: 0.5 liang Pi Shuang. Mix with vinegar to paste. Store in bowl until dry. Scrape off. Size of millet grain, wrap in cotton, place in gum line. Remove next day; worms die naturally. Chronic cases heal within three days. (*Pujifang*)
Scrofula on neck: Grind Xin Zhou Pi Huang. Mix with thick ink juice to make pills size of wu zi. Dry-fry in pot. Store in bamboo tube. Puncture with needle, apply half-pill to lesion. Lesion falls off naturally after corrosion completes. (*Lingyuan Fang*) Phlegm-Asthma: See Grain Section, under Fermented Soybean.
All fistulas with openings: Use Xin Shi, fire-calcine on new tile, grind to powder. Mix with saliva, apply to paper twist, insert into fistula to corrode bad tissue. Do not fill completely if discharge is heavy. Most excellent. (*Jijiu Liangfang*)