邵公曰∶自初发热，便知吉凶，重则痘密，轻则痘稀，日半出齐，灵丹莫疗，缓
延三日，续敷可生。初出之苗，根润顶尖，必易起壮；头焦脚滞，终难行浆。肉里藏
隐红斑，再察天离苗势，此位粗肥有润，用药退转为轻。大抵微热三天，身凉见标，斯
为上吉；若日半两日，带热见点，此是至凶。初热为始至，六日满方齐，若二三四
五日内见苗，热未退者，悉用退火解毒，直待分地清白；七日之后方可补托助浆。九
日之期，顺者饱满充实，逆者粘肉干枯，险者离巽起窠。无浆脚润，十日渐长，十二
三日头面俱满于中，或有变证，用药调治，可保无虞。痘若起胀行浆，再看舌、喉、背、
耳。舌如黑者必死，背无浆者定亡，耳上干枯必败，喉间堆锁定伤。脓若稠坚，靥
自浓实；浆嫌清少， 必黑焦。脚润浆坚，何患诸变；气亏血欠，立恐灾殃。八日之
前，食少无害，十日已后，少食宜防。出际通红莫嫌，壮期泄水可恶。声清为喜，声
哑难扶。假如切牙，当辨寒热。如逢战栗，验浆有无。热战切牙，托热凉散；寒战噤
齿，补带温攻。凶逆详察其两端，治止主持于一定。有能知此者，则不患名节之不彰，财利之不广也。
又曰∶观其耳便知痘出证轻证重，聆其声则知何部痘密痘稀。惟见疮善识心思，
观面知身上灾殃。又如身热唇焦，便知作渴；痘苗红紫，必发狂言。痘若稀疏，先
须头痛；形如蚕种，初主腰痛。面带白黄，
曾经吐泻；身如灾火，必定尿黄。蛇蜕一般，因热日半；一齐涌出；茱萸一样。连
烧二日，陆续敷阳。痘若润泽稀疏，定热三日身凉见点；苗若干枯略密，未满三日
带热敷疮。头面痘红，肚胁上必生斑点；颧腮痘陷，腰背间多有陷塘。白色浆清，再
出一层小痘；疮平顶陷，中有几个贼疮。浆不满充，犹恐唇舌龈疳落齿； 如易落，切
防肢节痈毒流脓。靥后眼封，毒入肝经。生臀收期复胀，邪留肠胃二经。此乃秘诀，发
之必中；宗吾法者，超乎俗类。
邵公说：从最初发热开始，就能判断吉凶。病情重的则痘疹密集，病情轻的则痘疹稀疏。如果半天之内就出齐了，即使有灵丹妙药也难以治疗；如果缓慢拖延三天，陆续发出，还有生机。刚发出的痘苗，根部滋润、顶端尖锐，一定容易起发壮实；如果顶端焦枯、根部滞涩，最终很难行浆结痂。如果肉里隐藏着隐现的红斑，再观察天离穴部位的苗势，这个部位如果粗大肥厚且有润泽感，用药后能退转为轻症。大体上，微热三天，身体凉爽后见到痘标，这是上等的吉兆；如果半天或两天内，带着热度就见到痘点，这是最凶险的征兆。初热是开始的阶段，到第六天出满才算齐备。如果在第二、三、四、五天内就见到痘苗，而热度还没有消退，全部使用退火解毒的方法，直到痘疹分布清晰、底色清白；七天之后才可以补益托毒、助长脓浆。到了第九天，顺证的痘疹饱满充实，逆证的粘肉干枯，险证的离巽穴部位起窠隆起。如果没有浆脚润泽，十天逐渐变长，十二三天头面都出满了，可能会有变证，用药调治，可以保全无虞。痘疹如果起胀行浆，再看舌头、咽喉、背部、耳朵。舌头像黑色的一定要死，背部没有浆的一定要亡，耳朵上干枯的一定要败，喉间堆锁定伤。脓液如果稠密坚硬，结痂自然浓实；浆液如果嫌清稀量少，一定会黑焦。脚部润泽、浆液坚挺，还怕什么各种变证；如果气亏血少，立刻恐怕遭遇灾殃。八日之前，吃得少没有害处，十日以后，吃得少应当防备。出疹初期通红不要嫌弃，壮期泄水令人厌恶。声音清脆为喜，声音嘶哑难扶。假如咬牙，应当辨别寒热。如果遇到战栗，验证是否有浆。热战咬牙，用托热凉散的方法；寒战咬牙，用补带温攻的方法。凶逆之证详细考察其两端，治疗只主持于一定的原则。能够懂得这些的人，就不担心名声节操不显扬，财富利益不广博了。
又说：观察耳朵就知道痘出的证候是轻是重，聆听声音就知道哪部分痘密痘稀。只有看见疮疡善于识别心思，观察面部就知道身上的灾殃。比如身体发热嘴唇焦干，就知道要口渴；痘苗红紫，一定发狂言。痘疹如果稀疏，先须头痛；形状像蚕种，起初主腰痛。面色带白黄，曾经吐泻；身体像灾火，必定尿黄。像蛇蜕皮一样，因为热半天一齐涌出；像茱萸一样，连续烧两天，陆续敷阳。痘疹如果润泽稀疏，一定热三天身体凉爽见点；痘苗如果干枯略密，未满三天带着热敷疮。头面痘红，肚胁上必生斑点；颧腮痘陷，腰背间多有陷塘。白色浆清，再出一层小痘；疮平顶陷，中有几个贼疮。浆液不满充，还恐怕唇舌龈疳落齿；如果容易脱落，切防肢节痈毒流脓。结痂后眼睛封闭，毒入肝经。生在臀部收期复胀，邪留肠胃二经。这是秘诀，发挥它一定中肯；遵循我的方法的人，超越世俗之辈。
Shao Gong said: From the initial fever, one can know auspiciousness or inauspiciousness. Severe cases present with dense pustules (variolous eruptions), while mild cases present with sparse pustules. If they erupt completely within half a day, even miraculous elixirs cannot cure them; if they emerge slowly over three days, there is still hope for survival. The newly erupted pustule buds, with moist roots and sharp tips, will certainly rise vigorously; if the tips are scorched and the roots are sluggish, it will be difficult to form pus and scab eventually. If hidden red macules are concealed within the flesh, observe the trend of the buds at the Tianli acupoint (Tianli). If this area is coarse, plump, and moist, medication can transform it into a mild condition. Generally, slight fever for three days followed by a cool body before seeing the marks is an auspicious omen; if within half a day or two days, spots appear accompanied by fever, this is extremely ominous. Initial heat is the beginning stage; full eruption by the sixth day is considered complete. If buds appear within the second, third, fourth, or fifth days while heat has not subsided, all should use methods to clear fire and detoxify until the distribution is clear and the base color is pure white; only after the seventh day can tonification and support methods be used to assist pus formation. By the ninth day, favorable cases are full and solid, adverse cases have dry and adhering flesh, and dangerous cases show raised pits at the Lixun acupoint (Lixun). Without moist pus feet, by the tenth day they lengthen; by the twelfth or thirteenth day, the head and face are fully covered. There may be complicated symptoms; with medication treatment, safety can be ensured. When pustules swell and form pus, also examine the tongue, throat, back, and ears. A black tongue indicates certain death; lack of pus on the back indicates certain demise; dryness on the ears indicates failure; blockage in the throat indicates fatal injury. If pus is thick and firm, scabs will naturally be dense and solid; if pus is thin and scanty, it will surely turn black and scorched. With moist feet and firm pus, why worry about various complications? If qi is deficient and blood is lacking, disaster is imminent. Before the eighth day, poor appetite is harmless; after the tenth day, poor appetite should be guarded against. Redness during the initial eruption phase should not be disliked; water leakage during the vigorous phase is detestable. Clear voice is auspicious; hoarse voice is difficult to manage. If teeth are clenched, distinguish between cold and heat. If shivering occurs, verify the presence of pus. Heat-induced shivering and teeth clenching require methods to support heat and disperse coolness; cold-induced shivering and jaw locking require tonifying methods combined with warming attacks. Detailed examination of adverse signs determines treatment, which must adhere to fixed principles. Those who understand this need not worry about their reputation or wealth not being abundant.
He also said: Observing the ears reveals whether the smallpox syndrome is mild or severe; listening to the voice reveals which areas have dense or sparse eruptions. Only by observing sores can one discern the patient's state; observing the face reveals bodily afflictions. For example, body heat and dry lips indicate thirst; red and purple pustule buds indicate delirium. If eruptions are sparse, headache usually precedes them; shapes resembling silkworm eggs initially indicate lower back pain. A complexion showing white and yellow suggests prior vomiting and diarrhea; a body feeling like "disaster fire" indicates yellow urine. Eruptions appearing like snake skin shed due to heat, erupting all at once in half a day; those resembling dogwood berries burn continuously for two days, emerging gradually on the yang side. If eruptions are moist and sparse, there will definitely be three days of fever followed by a cool body before spots appear; if buds are dry and slightly dense, without waiting for three days, apply medication to the sores while fever persists. Red eruptions on the head and face imply spots will arise on the abdomen and flanks; depressed eruptions on the cheeks and zygomatic area imply depressions on the waist and back. White pus with clear fluid implies a second layer of small eruptions will appear; flat-topped and depressed sores imply the presence of "thief sores." Insufficient pus filling raises fear of gum disease causing tooth loss; if scabs fall off easily, guard against abscesses in limbs draining pus. After scabbing, closed eyes indicate toxin entering the Liver Meridian (Gan Jing). Swelling recurring at the end stage on the buttocks indicates evil lingering in the Stomach and Intestines meridians. This is a secret method; applying it ensures accuracy; those following my methods surpass ordinary practitioners.