《金匮》云∶风寒湿三气杂至，合而成痹也。其风气胜者，为行痹；寒气胜者，为痛痹
；湿气胜者，为着痹。经云∶风胜则动，热胜则肿。想因寒湿阻络，化火蒸热，营卫失和，
遍体节骱酸楚掣痛而为历节风痹。起时寒热，或先发于手，或先发于足，或遍体皆发；或发
一骱漫肿，至七日始退，再发一骱，或止发于一处。总以湿热轻重之分。如发于气分者，其
色白；发于血分者，其色红。用药以透表燥湿解肌，俟热减肿退，再以和营通络。有数月不
愈者，以邪去营亏，当用补益。
漏肩风，肩骱酸楚，或疼痛漫肿，亦因风寒湿阻络而发。用药与前证同。
杨梅疮者，实名洋霉疮，又名时疮，又名棉子疮。总由湿热邪火所化。若疮毒传染气化
者轻，此肺脾二经受毒，其疮先见于上部，皮肤作痒，筋骨不疼，其形小而且干，坚实凸起
，有似棉子，故有棉子之名。此毒在皮肤，未经入络，治宜发散解毒，如防风通圣散、麻黄
一剂饮俱可。若淫女媾精，精化欲染者重，乃肝肾受毒，或先发下疳，或先患鱼口，然后
始生此疮，先从下部见之，渐至遍身，大而且硬，湿而后烂，筋骨多疼，小便涩淋，此证最
重。因其毒瓦斯内入骨髓，外达皮毛，若非汗下兼行，何以洗濯其脏腑乎？斯时即宜用鸡子大
黄丸，或九龙丹等泻之，使毒浊从来路而出，是为正治；切不可用轻粉、升丹等药遏之。梅
疮一服轻粉，其毒入筋骨，如油入面，莫之能解，积久外攻，势必至结毒溃烂，见诸恶证，
每难措手，甚有为害一身，而并殃及妻儿者，皆轻粉、升丹遏药之贻患也。大抵世之治杨梅
疮者，其法有四∶有遏抑其毒而不令其出者；有重用行药而行去其毒者；有用升发之剂而发
出其毒者；有用解托之剂而败去其毒者。四者之中，升发解托，虽未能使毒一时尽出，必久
而取效，然施之可以无弊；至于遏抑内收，贻害非浅，固不可用矣；即重用行药，每致大伤
元气，医者岂可不审虚实而轻用之乎？若其人疮发已久，气血已虚，毒犹未退，此即不可泻
，宜施解毒托散之法，要在临证变通可也。外此，又有薰条、擦药、哈吸等法，亦非善道，
宜屏去之。至如掺药收口，必俟其人筋骨不疼，疮根淡白，内毒已散，方可用之；否则，敛
早遗毒，亦不能无后患也。
乃若结毒之证，其初起也，必先筋骨疼痛，渐渐肿起，发无定所，随处可生；发在关节
，则损伤筋骨，纵愈，曲直不便；发于口鼻，崩梁缺唇，虽痊，形必破相；发于咽喉，更变
声音；发于手足，妨于行动；入于巅顶，头疼欲破，两眼胀痛，其疮起处，色紫而黑，穿溃
后黄脓泛滥，污水淋漓，臭腐不堪，口内凹进凸出，如湖石之状。皆由毒瓦斯遏郁，沉伏骨髓
，外攻使然。考之疡科书中，所载调治之方，计以百数，然大概仍不越乎泻与遏两端，内惟
仙遗粮汤、金蝉脱甲酒，虚弱者芎归二术汤，年久者五宝丹，不敛者十全大补汤，用土茯苓
煎服，数方可用。近今有十味淡斋方，最为灵效，其药品纯粹，不独愈其患，亦能尽解余蕴
之毒，永不再发也。
《金匮要略》中说：风、寒、湿三种邪气混杂侵袭人体，结合而形成痹证。其中风气偏盛的，称为行痹；寒气偏盛的，称为痛痹；湿气偏盛的，称为着痹。医经说：风邪偏盛则肢体动摇不定，热邪偏盛则局部红肿。推测这是由于寒湿阻滞经络，郁久化火蒸腾发热，导致营卫失调，全身关节酸痛、牵掣疼痛而形成的历节风痹（一种以全身关节疼痛为主症的疾病）。发病时伴有恶寒发热，有时先发于手部，有时先发于足部，有时全身都发作；有时只发作一个关节漫肿，到第七天才消退，接着再发作另一个关节，或者只固定在一个部位发作。这总归是由湿热邪气的轻重程度不同所致。如果病发在气分，疮色发白；病发在血分，疮色发红。用药应以透表、燥湿、解肌为主，等到热势减退、肿胀消退后，再用调和营血、疏通经络的药物。如果有数月不愈的，是因为邪气已去但营血亏虚，应当使用补益药物。
漏肩风（肩部风寒湿痹），表现为肩关节酸痛，或疼痛伴漫肿，也是由于风寒湿邪阻滞经络而引发。用药方法与上述病症相同。
杨梅疮（梅毒），实名洋霉疮，又名时疮，又名棉子疮。总归是由湿热邪火所化生。如果是通过疮毒传染、气化传播的，病情较轻，这是肺、脾二经受毒，疮疡首先出现在身体上部，皮肤瘙痒，筋骨不疼，疮形小而干燥，坚实凸起，形状像棉籽，所以有“棉子疮”的名称。这种毒邪在皮肤表面，未进入经络，治疗宜用发散解毒的方法，如防风通圣散、麻黄一剂饮都可以使用。如果是因淫乱性交，精液转化出的欲染之毒，病情较重，这是肝、肾受毒，或者先发生下疳（生殖器溃疡），或者先患鱼口（腹股沟淋巴结炎），然后才生出此疮，先从身体下部出现，逐渐蔓延至全身，疮形大而且硬，潮湿后溃烂，筋骨多疼痛，小便涩滞淋沥，此证最为严重。因为毒瓦斯内入骨髓，外达皮毛，如果不是汗法与下法兼用，怎么能洗涤清除脏腑中的毒素呢？此时就应当使用鸡子大黄丸，或九龙丹等药物进行泻下，使毒浊从大便排出，这才是正确的治法；切不可使用轻粉、升丹等药物来遏制毒邪。杨梅疮一旦服用轻粉，毒邪就会深入筋骨，如同油渗入面粉中，无法解脱，积聚日久向外攻发，势必导致结毒溃烂，出现各种恶证，往往难以处理，甚至有危害全身，并殃及妻儿的，这都是轻粉、升丹等遏药留下的祸患。大抵世间治疗杨梅疮的方法，主要有四种：有遏制抑制毒邪而不让它排出的；有重用攻下药来驱除毒邪的；有用升发药剂将毒邪发散出来的；有用解托药剂败解毒邪的。这四种方法中，升发和解托，虽然不能使毒邪一时尽出，但久而久之必见成效，然而施用这些方法没有弊端；至于遏制抑制、向内收敛，留下的祸害非浅，本来就不可以使用；即使是重用攻下药，常常导致严重损伤元气，医生难道可以不审察虚实而轻易使用吗？如果患者疮发已久，气血已经虚弱，毒邪仍未退去，这就不可再用泻法，适宜施用解毒托散的方法，关键在于临证时灵活变通罢了。除此之外，又有薰条、擦药、哈吸等方法，也不是好的途径，应当摒弃不用。至于掺药收口，必须等到患者筋骨不疼，疮根颜色淡白，内毒已经消散，才可以应用；否则，收敛过早遗留毒邪，也不能没有后患。
至于结毒（梅毒晚期并发症）这一病症，初起时，必定先出现筋骨疼痛，渐渐肿起，发作没有固定位置，随处可生；发在关节处，则损伤筋骨，即使痊愈，弯曲伸直也不便；发于口鼻，鼻梁崩塌嘴唇缺损，即使痊愈，容貌也必然破相；发于咽喉，更改变声音；发于手足，妨碍行动；侵入头顶，头痛欲裂，两眼胀痛，疮疡起始处，颜色紫黑，穿溃后黄脓泛滥，污水淋漓，臭腐不堪，口腔内部凹进凸出，像湖石一样。这都是由毒瓦斯被遏制郁结，沉伏在骨髓，向外攻发所致。考察疡科书籍中，所载调理治疗的方剂，数以百计，然而大概仍不超出“泻”与“遏”两端，其中唯有仙遗粮汤、金蝉脱甲酒，体虚者用芎归二术汤，病程长久者用五宝丹，疮口不收敛者用十全大补汤，配合土茯苓煎服，这几个方子可以使用。近来有十味淡斋方，最为灵验有效，其药品纯粹，不仅能治愈病患，也能彻底解除残余蕴藏的毒邪，永远不再复发。
According to the *Jin Gui Yao Lue* (Essential Prescriptions of the Golden Cabinet): When Wind, Cold, and Dampness pathogenic factors mix and invade together, they combine to form Bi Syndrome (Obstruction Syndrome). When Wind is predominant, it is called Xing Bi (Wandering Bi); when Cold is predominant, it is called Tong Bi (Painful Bi); when Dampness is predominant, it is called Zhuo Bi (Fixed Bi). The classics state: "When Wind is predominant, there is movement/tremor; when Heat is predominant, there is swelling." It is presumed that this arises from Cold-Damp obstructing the collaterals, transforming into Fire and steaming with Heat, leading to disharmony between Ying (Nutritive) and Wei (Defensive) Qi, resulting in global joint soreness, pulling pain, and forming Li Jie Feng Bi (Lijie Wind-Bi, a type of arthritis characterized by severe joint pain). Onset is accompanied by aversion to cold and fever. It may start in the hands, or in the feet, or affect the whole body; sometimes only one joint becomes diffusely swollen, subsiding after seven days, then another joint attacks, or it remains fixed in one location. This generally depends on the severity of Damp-Heat. If the pathology is in the Qi level, the color is white; if in the Blood level, the color is red. Medication should focus on releasing the exterior, drying Dampness, and relaxing the muscles. Once heat subsides and swelling recedes, use herbs to harmonize Ying blood and unblock collaterals. For cases lasting several months without healing, since pathogens have been expelled but Ying blood is deficient, tonification should be used.
Lou Jian Feng (Leaking Shoulder Wind), characterized by soreness in the shoulder joint, or pain with diffuse swelling, is also caused by Wind-Cold-Damp obstructing the collaterals. The medication used is the same as for the aforementioned condition.
Yang Mei Chuang (Plum-knot Sore, syphilis), formally known as Yang Mei Chuang, also called Shi Chuang (Seasonal Sore) or Mian Zi Chuang (Cotton-seed Sore). It is entirely generated by Damp-Heat pathogenic fire. If transmitted via infectious sores through qi transformation, the condition is mild; this involves toxicity in the Lung and Spleen meridians. The sores first appear on the upper body, causing skin itching without bone/muscle pain. The lesions are small, dry, firm, and raised, resembling cotton seeds, hence the name "Mian Zi Chuang." Since the toxin is in the skin and has not entered the collaterals, treatment should employ dispersing and detoxifying methods, such as Fang Feng Tong Sheng San (Saposhnikovia Powder to Unblock the Intestines) or Ma Huang Yi Ji Yin (Ephedra One-Dose Decoction). If contracted through illicit sexual intercourse, where semen transforms into desire-induced infection, the condition is severe; this involves toxicity in the Liver and Kidney meridians. It may begin with Xia Gang (Chancre) or Yu Kou (Fish Mouth, inguinal lymphadenitis), followed by these sores appearing first on the lower body and gradually spreading to the whole body. The lesions are large, hard, become wet and ulcerate upon moisture, cause bone/muscle pain, and present with dysuria and strangury. This is the most severe presentation. Because the toxic vapors enter the marrow internally and reach the skin externally, unless sweating and purging methods are combined, how can the viscera be washed clean? At this time, Ji Zi Da Huang Wan (Chicken Egg Large Rhubarb Pill) or Jiu Long Dan (Nine Dragons Pill) should be used to purge, allowing toxic turbidity to exit via the bowels; this is the correct treatment. One must absolutely avoid using Qian Fen (Calomel) or Sheng Dan (Red Mercury Oxide) to suppress the toxin. If Yang Mei Chuang is treated with Qian Fen, the toxin enters the bones and muscles like oil penetrating flour, becoming inseparable. Accumulated over time, it attacks outward, inevitably leading to Jie Du (Knotting Toxors) and ulceration, manifesting as various malignant symptoms, often difficult to manage, and potentially harming the whole body and even affecting spouses and children. These disasters are all consequences of using suppressing agents like Qian Fen and Sheng Dan. Generally, there are four methods for treating Yang Mei Chuang in the world: 1) Suppressing the toxin to prevent its exit; 2) Heavily using purgatives to drive out the toxin; 3) Using ascending/dispersing agents to release the toxin; 4) Using resolving/supporting agents to defeat the toxin. Among these, ascending and resolving methods, though unable to expel the toxin immediately, will eventually take effect and carry no harm. Conversely, suppression and internal retention cause profound damage and must not be used. Even heavy purging often severely damages Yuan Qi (Primal Qi); how can physicians lightly use these without assessing deficiency and excess? If the patient has had sores for a long time, Qi and Blood are already deficient, yet the toxin remains, purging is contraindicated. Instead, detoxifying and supporting dispersion methods should be employed, requiring flexibility in clinical practice. Besides these, fumigation strips, topical rubs, and inhalation methods are not good approaches and should be discarded. Regarding powders to close wounds, they should only be used after bone/muscle pain ceases, the sore base turns pale white, and internal toxins have dispersed; otherwise, premature closure leaves residual toxins, leading to future complications.
As for Jie Du (Knotting Toxors, late-stage syphilis), initially, there is bone/muscle pain, followed by gradual swelling arising unpredictably anywhere. If it occurs at joints, it damages bones and tendons; even if healed, flexion and extension are impaired. If it occurs in the mouth or nose, it causes collapse of the nasal bridge and loss of lips; even if healed, disfigurement remains. If it occurs in the throat, it alters the voice. If it occurs in hands and feet, it impedes movement. If it invades the crown, it causes splitting headaches and distending eye pain. The initial site of the sore is purple-black; after ulceration, yellow pus floods, foul water drips continuously, and the odor is unbearable. The oral cavity becomes concave and convex, resembling karst rocks. All these result from toxic vapors being suppressed and stagnant, sinking into the marrow, and attacking outward. Examining surgical texts, there are hundreds of formulas for regulation and treatment, but generally, they do not exceed the two ends of "Purging" and "Suppressing." Among them, only Xian Yi Liang Tang (Immortal Wild Yam Decoction), Jin Chan Tuo Jia Jiu (Golden Cicada Shedding Shell Wine), Xiong Gui Er Zhu Tang (Angelica and Atractylodes Two-Atractylodes Decoction) for the weak, Wu Bao Dan (Five Treasures Pill) for chronic cases, and Shi Quan Da Bu Tang (Comprehensive Great Tonifying Decoction) for non-healing sores, along with Tu Fu Ling (Smilax Glabra Rhizome) decoction, are usable. Recently, the Shi Wei Dan Zhai Fang (Ten-Ingredient Dan Zhai Formula) has proven most effective. Its ingredients are pure; not only does it cure the disease, but it also completely resolves residual latent toxins, preventing recurrence forever.