丹溪曰∶手腕痈，生手腕外面，属手三阳经，由风火湿毒凝结而成。乃皮肉浇薄之处，
若迁延日久不溃，或漫肿平塌；既溃，腐烂露骨者逆，难于收功。若肿硬 赤不烂，而多生
头者，即名鼓槌疯，又名手腕疽。
兑疽，生手腕里面，横纹后前梢动脉之间，又名脉疽。初起寒热肿痛，痛彻手膊，举
动不便。此乃肺金门户，若溃深则肺气大泄，最为危候。以上二证，均仿疔疽调治。
手发背，发于手背中渚、液门二穴，属手少阳三焦经，若发于正中劳宫，属手厥阴心包
络经，由风热相乘，气血壅滞而结。初起形如芒刺，憎寒恶热，昏闷作痒，疼痛呕逆，遂满
手背高肿，后聚毒成疮，深入至骨。成脓溃速者顺；若漫肿坚硬，溃迟为疽；又有初起一粒
高肿，隔日即烂，此属湿火。初宜俱用荆防败毒散，次用黄连解毒汤，或犀角地黄汤。（有
将手背尽行烂去者，须掺珍珠散，贴白玉膏收功）
手心毒，一名擎珠毒，又名瘭疽，属手少阴心、手厥阴心包络二经湿火之毒所结也。其
疮如泡，色如血赤，外形虽小，内毒有余，疼痛非常，日夜无间，此证往往有不能收功，流
血至死者。治法必用大补水之剂，佐以解毒之味，如地丁、银花、元参、生地、当归、丹皮
、贝母之属。
托盘疔，生于手掌中心，系手厥阴、少阴二经之所司也。由心火炽甚，逼血妄行，肝风
鼓舞，毒散四肢，加以忧思过度，酒色不节，遂至毒流骨髓，侵于劳宫，劳宫系心经之脉络
，故毒生焉。初起坚硬起泡，其泡明亮者即挑之。治以银花解毒汤。
朱丹溪说：手腕痈，生于手腕外侧，归属于手三阳经，由风、火、湿、毒邪气凝结而成。此处是皮肉浅薄之处，如果拖延日久不化脓溃破，或者出现漫肿平塌；一旦溃破后，腐烂露出骨骼的属于逆证，难以治愈收功。如果肿胀坚硬、色红但不腐烂，且多头并生的，就称为鼓槌疯，又名手腕疽。
兑疽，生于手腕内侧，横纹后方前梢动脉之间，又名脉疽。初起时伴有寒热、肿痛，疼痛放射至手臂，活动不便。这里是肺金的门户，如果溃烂过深则肺气大量外泄，是最为危险的证候。以上两种病症，均参照疔疽的方法进行调治。
手发背，生于手背部的渚穴、液门穴，归属于手少阳三焦经；若生于正中的劳宫穴，则归属于手厥阴心包络经，由风热邪气相乘，导致气血壅滞而结聚。初起时形状如芒刺，憎恶寒冷又怕热，头昏闷痒，疼痛伴呕吐呃逆，随即满手背高肿，后来聚集成毒形成疮疡，深入至骨。成脓溃破迅速的属于顺证；如果漫肿坚硬，溃破迟缓的则为疽；又有初起时一粒高肿，隔日即腐烂的，这属于湿火。初起时都宜先用荆防败毒散，随后用黄连解毒汤，或犀角地黄汤。（若有将手背全部烂去的，必须掺敷珍珠散，贴白玉膏以收功）
手心毒，一名擎珠毒，又名瘭疽，归属于手少阴心经、手厥阴心包络经湿火之毒邪结聚所致。其疮疡如泡状，颜色如血般赤红，外形虽小，但内部毒邪有余，疼痛非常剧烈，日夜无间断，此证往往难以收功，甚至因流血过多而死。治疗方法必须使用大补阴液的方剂，佐以解毒的药物，如地丁、银花、元参、生地、当归、丹皮、贝母之类。
托盘疔，生于手掌中心，由手厥阴、手少阴二经所主管。由于心火炽盛，逼迫血液妄行，肝风鼓动，毒邪散布四肢，加上忧思过度，酒色不节，致使毒流注骨髓，侵袭劳宫穴。劳宫穴是心经的脉络所在，所以毒邪在此生成。初起时坚硬起泡，如果泡明亮就挑破它。治疗用银花解毒汤。
Zhu Danxi stated: Wrist carbuncle (Wanshou Yong) arises on the outer side of the wrist, belonging to the Three Yang Meridians of the Hand. It is formed by the coagulation of wind, fire, dampness, and toxin pathogens. This area is where the skin and flesh are thin and shallow. If it lingers for a long time without suppurating and ulcerating, or presents with diffuse swelling and flat collapse; once ulcerated, if it rots and exposes bone, it is considered a adverse condition (Ni), difficult to heal. If it is swollen and hard, red but not rotting, and produces multiple heads, it is named Drumstick Madness (Guchui Feng), also known as Wrist Carbuncle (Wanshou Ju).
Dui Ju arises on the inner side of the wrist, between the transverse crease posteriorly and the anterior tip of the radial artery, also known as Pulse Carbuncle (Mai Ju). Initially, it presents with chills, fever, swelling, and pain, with pain radiating through the arm, making movement inconvenient. This is the gate of Metal of the Lung. If the ulceration is deep, Lung Qi will be severely depleted, which is a critical prognosis. Both of the above conditions should be treated according to the principles for Ding Ju (Ting Ju).
Hand Back Carbuncle (Shou Fa Bei) arises at the Zhuxu (Zhongzhu, SI3) and Yemen (Yemen, TE2) acupoints on the back of the hand, belonging to the Triple Energizer Meridian of the Hand-Shaoyang. If it arises at the center of Laogong (Laogong, PC8), it belongs to the Pericardium Meridian of the Hand-Jueyin. It is caused by wind-heat pathogens multiplying each other, leading to stagnation and coagulation of Qi and Blood. Initially, it resembles thorns, accompanied by aversion to cold, fear of heat, dizziness, stuffiness, itching, pain, vomiting, and retching, followed by high swelling over the entire back of the hand. Later, toxins gather to form sores, penetrating deeply to the bone. Rapid suppuration and ulceration indicate a favorable course (Shun); diffuse swelling and hardness with delayed ulceration indicate Ju (Carbuncle). Another type presents initially as a single high-swelling nodule that rots within two days, which belongs to Damp-Fire. Initially, Jingfang Baidu San (Jingfang Decoction for Overcoming Toxins) should be used, followed by Huanglian Jiedu Tang (Coptis Decoction for Resolving Toxins) or Xijiao Dihuang Tang (Rhinoceros Horn and Rehmannia Decoction). (If the entire back of the hand is eroded, Zhenzhu San (Pearl Powder) must be applied, and Baiyu Gao (White Jade Ointment) pasted to promote healing.)
Palm Toxicity (Shouxin Du), also known as Qingzhu Du or Biao Ju, is caused by the coagulation of Damp-Fire toxin pathogens in the Heart Meridian of the Hand-Shaoyin and the Pericardium Meridian of the Hand-Jueyin. The sore resembles a blister, colored crimson like blood. Although small externally, the internal toxin is excessive, causing severe pain without relief day or night. This condition often fails to heal and can lead to death from hemorrhage. The treatment method must employ formulas that greatly nourish Yin fluids, assisted by detoxifying herbs such as Dideng (Viola Herba), Yinhua (Lonicerae Japonicae Flos), Yuan Shen (Scrophulariae Radix), Sheng Di (Rehmanniae Radix), Dang Gui (Angelicae Sinensis Radix), Dan Pi (Moutan Cortex), and Bei Mu (Fritillariae Bulbus).
Tray Ding (Tuopan Ding) arises in the center of the palm, governed by the Pericardium Meridian and the Heart Meridian of the Hand. It is caused by blazing Heart Fire forcing blood to move recklessly, Liver Wind stirring, and toxins dispersing to the four limbs. Combined with excessive worry and thought, and immoderation in alcohol and sexual activity, the toxin flows into the bone marrow and invades Laogong. Laogong is the meridian pathway of the Heart, hence the toxin generates there. Initially, it becomes hard and forms blisters; if the blisters are bright, they should be punctured. Treatment uses Yinhua Jiedu Tang (Honeysuckle Detoxification Decoction).