治疡患初起，不论大小各证，阴发阳发。宣通经络，行气活血，消散退肿，解毒定痛如
神。惟头面疔毒忌之。
制香附 西羌活 全当归 川断肉（各三两） 生远志肉（二两） 明腰黄 白明矾（各一
两） 广
滴
三钱）
以上各为细末和匀，另用真杜蟾酥二两六钱汾酒浸化，同杵丸如绿豆大，辰砂为衣。小
证每服分许，大证须服一钱至一钱五分。如初起酸痛坚肿能饮酒者，用热黄酒吞丸；不能饮
酒者，当归、木香煎汤送服。须囫囵吞，不可嚼碎。如肿痛已甚，势欲酿脓者，亦可服，但
稍减之；即脓成后，四围余块尚坚者亦可服，以消尽坚肿为度。
【方解】 外科之有蟾酥退毒丸旧矣，然其方颇杂，殊未易效。此黄墙朱氏改定
之方，
寿颐于庚戌八月在沪上治一妇人，腰疽大痛，形已高突，背脊酸楚异常，势有蒸脓之状，知
是大证可危。授以是丸约三钱许，嘱分三服，用热陈酒吞，每日一服。不意此人并作一次服
之，且饮酒不少。黄昏吞药，至夜半大热如焚（本有身热但不甚炽），神志迷蒙，几至不识人
事
毕即往视之，则热已大退，神志已清，自说背痛锐减，转侧轻捷。再与宣通煎剂，不劳更方
而愈。可见是药效力之神。药不瞑眩，厥疾不瘳，是之谓乎。
治疗疮疡疾病初起阶段，无论病情轻重各类证候，无论是阴证还是阳证发作。此方能宣通经络，行气活血，消散退肿，解毒定痛，效果如神一般。唯独头面部的疔毒忌用此方。
制香附、西羌活、全当归、川断肉（各三两）、生远志肉（二两）、明腰黄、白明矾（各一两）、广滴（三钱）。
将以上药材分别研为细末并混合均匀，另外取真杜蟾酥二两六钱，用汾酒浸泡化开，与药末一同捣匀，制成如绿豆大小的丸剂，以辰砂为衣。小病证每次服用分许，大病证需服用一钱至一钱五分。如果在初起阶段出现酸痛坚肿且能饮酒者，用热黄酒送服丸药；不能饮酒者，用当归、木香煎汤送服。必须整粒吞服，不可嚼碎。如果肿痛已经非常严重，形势即将酿脓者，也可以服用，但剂量稍减；即使脓已成后，四周剩余的硬块仍然坚硬者也可以服用，以消除尽坚肿为限度。
【方解】外科使用的蟾酥退毒丸历史悠久，然而其方剂组成颇为杂乱，确实难以见效。这是黄墙朱氏修改确定的方子。我在庚戌年八月在上海治疗一位妇人，患有腰疽，疼痛剧烈，肿块已经高突，背脊酸楚异常，形势有蒸酿脓液的状态，知道是大证且情况危急。给予此丸约三钱左右，嘱咐分三次服用，用热陈酒送服，每日一服。没想到此人将药一次全部服下，并且饮酒不少。黄昏时吞服药，到了半夜身体大热如火烧（原本就有身热但不甚炽烈），神志迷蒙，几乎不认识人。我随即前往诊视，此时热势已大退，神志已清醒，自述背痛锐减，转身活动轻捷。再给予宣通煎剂，无需更动方剂而痊愈。可见此药效力之神妙。“药不瞑眩，厥疾不瘳”，说的就是这种情况吧。
For the initial stage of treating ulcerative diseases, regardless of severity or specific syndromes, whether Yin-type or Yang-type eruptions, this formula can unblock meridians (Meridians), promote Qi circulation and blood activation, dissipate swelling, detoxify, and relieve pain with miraculous efficacy. However, it is contraindicated for Ding-toxin (Furuncle toxin) on the head and face.
Prepared Cyperi Rhizoma (Zhi Xiangfu), Western Notopterygii Rhizoma et Radix (Xi Qianghuo), Complete Angelicae Sinensis Radix (Quan Danggui), Dipsaci Radix (Chuan Duanrou) (each 3 liang); Raw Polygalae Radix (Sheng Yuanzhi Rou) (2 liang); Ming Yao Huang (Ming Yaohuang), White Alum (Bai Mingfan) (each 1 liang); Guang Di (Guangdi) (3 qian).
Grind each ingredient into fine powder and mix evenly. Separately, take 2 liang 6 qian of genuine Bufo Toxin (Du Chan Su), soak and dissolve it in Fenjiu (Fen Wine), then pound together with the powder to form pills the size of mung beans, coated with Cinnabar (Chen Sha). For minor conditions, take a fen amount per dose; for major conditions, take 1 qian to 1.5 qian per dose. If at the initial stage there is soreness, hardness, and swelling, and the patient can drink alcohol, swallow the pill with hot yellow wine; if unable to drink alcohol, administer with decoction of Angelicae Sinensis Radix (Danggui) and Aucklandiae Radix (Muxiang). The pill must be swallowed whole, not chewed. If swelling and pain are severe and pus formation is imminent, it may also be taken, but with a slightly reduced dose; even after pus has formed, if hard lumps remain around the periphery, it may still be taken, until the hardness and swelling are completely dissipated.
[Formula Analysis] The use of Chan Su Tui Du Wan (Toad Venom Detoxification Pill) in surgery is old, yet its original formulation was rather complex and difficult to achieve effective results. This is the revised formula by Zhu from Huangqiang. In August of the Gengxu year, while treating a woman in Shanghai, I encountered a case of lumbar abscess (Yao Ju) with severe pain, where the swelling was already protruding high, accompanied by extreme soreness and stiffness of the back, indicating a critical condition with impending suppuration. I prescribed approximately 3 qian of this pill, instructing her to divide it into three doses, taken with hot aged wine, one dose daily. Unexpectedly, she took the entire amount at once and consumed a considerable amount of alcohol. After swallowing the medicine at dusk, by midnight, she developed intense fever like burning (she had pre-existing low-grade fever but not severe), and her mental state became confused, nearly failing to recognize people. I immediately visited her, finding that the fever had greatly subsided and her consciousness had cleared. She reported that her back pain had sharply decreased and her movements had become agile. Subsequently, I administered Xuan Tong Decoction (Xuantong Jian), and without further modification of the prescription, she recovered. This demonstrates the miraculous efficacy of this medicine. "If the medicine does not cause dizziness or nausea (mingxuan), the chronic disease will not be cured," as the saying goes.