圣散子方因东坡先生作序由是天下神之宋末辛未年永嘉瘟疫服此方被害者不可胜纪余阅
叶石林避暑录云宣和闲此药盛行于京师太学生信之尤笃杀人无数医顿废之昔坡翁谪居黄
州时其地濒江多卑湿而黄之居人所感者或因中湿而病或因雨水浸淫而得所以服此药而多效是
以通行于世遗祸于无穷也弘治癸丑年吴中疫疠大作吴邑令孙磐令医人修合圣散子遍施街衢
并
以其方刊行病者服之十无一生率皆狂躁昏瞀而卒噫孙公之意本以活人殊不知圣散子方中有附
子
良姜吴茱萸豆蔻麻黄藿香等剂皆性味燥热反助火邪不死何待若不辩阴阳二症一概施治杀人利
于刀剑有能广此说以告人人亦仁者之一端也
外台秘要载祝由一科丹溪谓之移精变气祝说病由而已可治小病若内有虚邪外有实邪当用
正大
之法然符水惟膈上热痰一呷凉水胃热得之岂不清快亦可取效若内伤涉虚之人及冬天严寒之时
符水下咽胃气受伤反致害者多矣予考之文献志云祝由南方神也或以祝训断谓但断绝其受病之
由二说两存之未知孰是
王好古此事难知云从乎中治中治者少阳也又云寒热俱伤必当从乎中治中治者温之也一书
两出而
各异余切有疑焉后阅东垣先生医学发明云此中字盖欲医人临病消息酌中用药耳是中庸所谓君
子而时中之义也此帮助白
圣散子方因为苏东坡先生写了序言,从此天下人将其视为神方。宋末辛未年(1271年),永嘉发生瘟疫,服用此方而受害的人不可胜数。我阅读叶梦得《避暑录话》记载:宣和年间,此药在京城盛行,太学生尤其深信不疑,导致杀人无数,医学因此一度荒废。
过去苏东坡被贬谪居住在黄州时,那里临近长江,地势低洼潮湿,当地居民所患的疾病,有的是因为感受湿邪致病,有的是因为雨水浸淫所致,所以服用此药大多有效,因此通行于世,却留下了无穷的祸患。弘治癸丑年(1513年),吴中地区瘟疫大流行,吴县县令孙磐命令医生配制圣散子,遍布街巷施舍给百姓,并将该方刊印发行。病人服用后,十无一活,大都表现为狂躁、昏厥而死亡。唉!孙公的本意本是救人,却不知道圣散子方中含有附子、良姜、吴茱萸、豆蔻、麻黄、藿香等药物,这些药材性味都属燥热,反而助长火邪,不死还等什么?如果不辨别阴阳两种证候,一概施用治疗,其杀伤力胜过刀剑。如果有能广泛传播这一观点以告知世人,也是仁者的一个方面。
《外台秘要》记载了祝由科,朱丹溪称之为“移精变气”,即通过祝说病由来治病,只能治疗小病。如果体内有虚邪,体外有实邪,应当使用正大之法。然而符水只适用于膈上热痰,喝一口凉水,胃热得到缓解,岂不快哉?也可以取得疗效。如果是内伤导致正气虚弱的人,以及冬天严寒之时,符水下咽损伤胃气,反而导致害处很多。我考察《文献志》记载:祝由是南方的神祇。有人将“祝”解释为“断”,认为只是断绝受病的缘由。这两种说法并存,不知道哪一个是正确的。
王好古在《此事难知》中说:“从乎中治”,中治指的是少阳经。又说:“寒热俱伤,必当从乎中治”,中治就是温补的方法。同一本书中两次出现却含义各异,我对此深切怀疑。后来阅读李东垣先生的《医学发明》,其中说这个“中”字,大概是希望医生在面对疾病时,斟酌权衡,用药适中。这正是《中庸》所说的“君子而时中”的含义。
The prescription of Shengsan Zi (Holy Dispersion Powder) became revered by the world as a divine remedy because Su Dongpo (Su Shi) wrote a preface for it. In the Xinwei year (1271) at the end of the Song Dynasty, an epidemic broke out in Yongjia; countless people suffered and died after taking this prescription. I read in Ye Shiming's *Bushu Luyu* (Record of Summer Retreat) that during the Xuanhe era, this medicine was prevalent in the capital city. The imperial students believed in it particularly strongly, resulting in countless deaths, causing medical practice to fall into disrepair for a time.
Previously, when Mr. Dongpo was demoted and resided in Huangzhou, the area was adjacent to the Yangtze River with low-lying and damp terrain. The illnesses contracted by the local residents were either due to dampness invading the interior or caused by prolonged exposure to rainwater. Therefore, taking this medicine was often effective, leading to its widespread circulation, yet leaving behind endless calamities. In the Guichou year (1513) of the Hongzhi era, a severe epidemic erupted in the Wuzhong region. Sun Pan, the magistrate of Wu County, ordered physicians to compound Shengsan Zi and distribute it freely throughout the streets and alleys, also publishing the prescription. Among those who took it, not one in ten survived; most exhibited mania, delirium, and unconsciousness before dying. Alas! Magistrate Sun’s original intention was to save lives, but he did not realize that Shengsan Zi contains herbs such as Fuzi (Prepared Aconite Root), Liangjiang (Galangal Rhizome), Wuzhuyu (Evodia Fruit), Doukou (Cardamom Seed), Mahuang (Ephedra Herb), and Huoxiang (Patchouli Herb). These ingredients are all acrid, warm, and drying in nature, which would instead exacerbate fire pathogens. How could death be avoided? If one fails to differentiate between Yin and Yang syndromes and applies treatment indiscriminately, the lethality surpasses that of swords and knives. If anyone can widely disseminate this insight to inform the public, it would indeed be one aspect of benevolence.
*Waitai Miyao* (Secret Essentials of the Outer Palace) records the discipline of Zhuyou (Incantation Therapy). Zhu Danxi referred to it as "Yijing Bianqi" (Transfining Spirit and Altering Qi), meaning healing by explaining the origins of illness through incantations. It is only suitable for minor ailments. If there are deficient pathogens internally and excess pathogens externally, one must employ orthodox and upright methods. However, talisman water is only applicable for heat-phlegm above the diaphragm; drinking cold water clears stomach heat, bringing relief and potentially achieving efficacy. But for individuals with internal injury involving deficiency, or during the severe cold of winter, swallowing talisman water damages Stomach Qi, often causing more harm than good. I consulted *Wenxian Zhi* (Records of Literature), which states: Zhuyou is a deity of the South. Some interpret "Zhu" as "Duan" (to cut off), suggesting it merely cuts off the cause of disease. Both theories coexist, and it remains uncertain which is correct.
Wang Haogu, in *Cishi Nan Zhi* (Difficulties in Understanding This Matter), stated: "Treating from the Middle," where "Middle Treatment" refers to the Shaoyang (Lesser Yang) channel. He further stated: "When both cold and heat injure the body, one must treat from the Middle," implying that Middle Treatment involves warming methods. The same concept appears twice in one book with different meanings, raising my deep suspicion. Later, reading Li Dongyuan's *Yixue Faming* (Clarification of Medical Principles), I found that this character "Zhong" (Middle) implies that physicians should weigh circumstances when facing diseases and prescribe medication with moderation. This aligns with the meaning of "the gentleman adapts to the mean according to the times" (*Shi Zhong*) from the *Doctrine of the Mean*.