（附秽浊）
徐仲光治一儿痘，紫色而不起胀，乃毒盛壅遏也。以紫草、红花、蝉蜕，煎酒，调独圣散服之，又以犀角
地黄治之，红润起胀而愈。
一儿痘，六日稠密紫滞，平陷而不起胀，烦躁闷乱，亦毒盛壅遏也，但分珠脚敛可治。以人中黄，每服三
分，酒调，连二服，色渐红活。又以犀角地黄汤加牛蒡、蝉蜕，痘绽突起胀而愈。
一儿痘血热重，初时纯与凉血解毒，犀角服过二两，石膏五钱一剂者，服过五剂。至十朝，略用参三分托
浆。十二朝外，浆清痂薄，用助托药加棉茧带蛾者七枚，糯米一合，渴时即以麦冬、糯米、棉茧，煎汤饮之。
又发水泡数个，浆疤暗长，灌烂遍身，复用茯苓、苡仁、白芍、黄连、银花、甘草、生地、骨皮、山楂、莲肉、
木通、连翘、牛蒡、荆芥而愈。（清热过重，故元气不能充浆，所以善治者于清热之时，即预为异日催浆之地，
庶不至打成两橛也。）
万世用云∶庚申春，家有顽童，仅十岁，患痘疮症，适仆寓乡之故卢，闻报急归，视其疾不为不急，且傍
有煎炒油腻，欲避莫能，荷育溪（曾世荣也。）疗之。恰七日，疮胀而光泽，偶因舍下有动厕秽触，觉色黯而
神昏，大为惊惧。育溪曰∶毋虑，吾有除秽药，投之必安。不数日，果如其言，遂拜更生。用扣其所用何剂？
曰∶中和汤，即十奇散，如沉、檀等剂而已，余无他巧。（《幼幼心书》。）
（附：秽浊证）
徐仲光治疗一名患痘疮的幼儿，痘色紫暗且不能起发充盈，这是毒邪炽盛、壅滞遏阻所致。用紫草、红花、蝉蜕煎酒，调服独圣散，又用犀角地黄汤治疗，痘色转为红润并起发充盈而痊愈。
另一名幼儿患痘疮，六天时痘粒稠密、色紫晦滞，平陷而不能起发充盈，伴有烦躁闷乱，这也是毒邪炽盛、壅滞遏阻所致，但若能分辨出痘根分明、收敛可治。用人中黄，每次服用三分，用酒调服，连服两次，痘色逐渐转为红活。又用犀角地黄汤加牛蒡子、蝉蜕，痘疹绽开突起、充盈饱满而痊愈。
另一名幼儿患痘疮血热严重，初起时纯用凉血解毒之法，犀角累计服用过二两，石膏每剂五钱，共服用过五剂。到了第十天，略用人参三分以托举痘浆。十二天以后，痘浆清稀、痂皮薄，使用助托药，加上棉茧带蛾者七枚，糯米一合，口渴时即用麦冬、糯米、棉茧煎汤饮用。
后来又发出数个水泡，痘浆结痂颜色暗滞，溃烂遍布全身，又复用茯苓、苡仁、白芍、黄连、银花、甘草、生地、骨皮、山楂、莲肉、木通、连翘、牛蒡、荆芥而痊愈。（清热药过重，导致元气不能充实痘浆，所以善于治疗的人，在清热之时，就预先为日后催发痘浆做准备，以免治疗脱节。）
万世用说：庚申年春天，家中有个顽皮的儿童，年仅十岁，患痘疮症。恰逢仆人寄居在乡下的旧卢地，听到消息急忙赶回，查看病情觉得并不紧急，且旁边有煎炒油腻之物，想避开却做不到，于是请荷育溪（即曾世荣）治疗。恰好第七天，痘疮胀大而光泽，偶然因为屋下有动厕的秽气触犯，觉得痘色变暗且神志昏沉，非常惊恐害怕。育溪说：“不要担心，我有除秽的药，投下必然平安。”没过几天，果然如他所说，于是拜谢获得新生。追问他用了什么方剂？回答说：“是中和汤，也就是十奇散，不过是沉香、檀香等药物罢了，其余没有别的巧妙之处。”（出自《幼幼心书》。）
(Attached: Turbid Pathogen Syndrome)
Xu Zhongguang treated a child with smallpox. The pustules were purple and failed to rise and swell, indicating excessive pathogenic heat and stagnation. He administered Du Sheng San (Solely Holy Powder) mixed with wine decocted from Zicao (Arnebiae Radix), Honghua (Carthami Flos), and Chantui (Cicadae Periostracum), followed by Xijiao Dihuang Tang (Rhinoceros Horn and Rehmannia Decoction). The skin turned ruddy, the pustules rose and swelled, and the patient recovered.
Another child presented with dense, purple, and sluggish smallpox lesions on the sixth day, which were flat, depressed, and failed to rise. The child suffered from restlessness and confusion, also due to excessive pathogenic heat and stagnation. However, it was deemed treatable if the distinct "pearl" formation could be observed. Renzhonghuang (Human Middle Yellow) was administered at 3 fen per dose, mixed with wine. After two doses, the color gradually became ruddy and vibrant. Subsequently, Xijiao Dihuang Tang (Rhinoceros Horn and Rehmannia Decoction) was modified with Niubangzi (Arctii Fructus) and Chantui (Cicadae Periostracum). The lesions opened, protruded, and swelled fully, leading to recovery.
In another case of severe blood-heat in smallpox, initial treatment consisted solely of cooling the blood and detoxifying. The patient consumed over 2 liang of Xijiao (Rhinocerotis Cornu) and 5 qian of Shigao (Gypsum Fibrosum) per dose for five doses. By the tenth day, a small amount of Renshen (Ginseng Radix et Rhizoma), 3 fen, was used to support the filling of the pustules. After the twelfth day, as the pus was clear and the scabs thin, supportive tonifying herbs were added, including seven silkworm pupae within cocoons and one he of Nuomi (Oryza Sativa Var. Glutinosa). When thirsty, the child drank a decoction of Maidong (Ophiopogonis Radix), Nuomi (Oryza Sativa Var. Glutinosa), and silkworm cocoons.
Later, several water blisters appeared, and the pus/scabs became dark and stagnant, with ulceration spreading over the body. Treatment with Fuling (Poria), Yiren (Coicis Semen), Baishao (Paeoniae Radix Alba), Huanglian (Coptidis Rhizoma), Yinhua (Lonicerae Japonicae Flos), Gancao (Glycyrrhizae Radix et Rhizoma), Shengdi (Rehmanniae Radix), Guipi (Phellodendri Cortex), Shanzha (Crataegi Fructus), Lianrou (Nelumbinis Semen), Mutong (Akebiae Caulis), Lianqiao (Forsythiae Fructus), Niubangzi (Arctii Fructus), and Jingjie (Schizonepetae Spica) led to recovery. (Excessive use of cold-clearing herbs depleted the Yuan Qi, preventing adequate pus formation. Therefore, skilled practitioners prepare for later stages of pus induction while clearing heat, avoiding disjointed treatment.)
Wan Shiyong stated: In the spring of Gengshen year, my ten-year-old son contracted smallpox. A servant residing in Lu village rushed back upon hearing the news. I examined him and found the condition not urgent; however, greasy fried foods nearby could not be avoided. Heo Yuxi (Zeng Shirong) was consulted. On the seventh day, the lesions were swollen and lustrous. Accidentally exposed to foul odors from a latrine, the lesions turned dark, and the child became comatose and terrified. Yuxi said, "Do not worry. I have herbs to remove turbidity; administration will ensure safety." Within a few days, it proved true, and the child was reborn. When asked about the prescription, he replied, "Zhonghe Tang (Harmonizing Decoction), which is essentially Shiqi San (Ten Wonders Powder), containing Chenxiang (Aquilariae Lignum Resinatum), Tanshen (Santalum Album Lignum), etc., with no other special tricks." (From *Youyou Xinshu*.)