发热时身无大热腰腹脚膝不痛，过三日才见红点，又坚硬碍指，此为吉证，不须服药。
发热时浑身温热，不时发惊，痘自心经出也，乃为吉证，可治而愈。
按∶近年，屡有痘前惊而终凶者，好事不如无，未可言吉。
发热之初，腹中大痛，腰如被杖，及至报痘干燥，而前痛犹不止者，死不治。
先腹痛，后止，可用助血气药救之。
初发热一日，遍身即现红点稠密如蚕种，摸过不碍手者，死不治。
初发热时，头面一片红如胭脂者，六日后死。
初发热时，用红纸捻蘸油点火，照心头皮肉里，红如一片胭脂，或遍身皆有成
块红者，八九日后死。
痘疮之期，始于见点，从见点而数之，期止七日，七日之内，如花之始蕾而发
也，其气日盛以出，七日之后，气敛而花谢矣，故服药者当于七日之内，日夜连服，
毋或姑息，苦之以七日，所以全之于百年，人不知此，而惟务姑息，七日之外，服
无益矣。予尝谓痘毒之在血气，譬若糠 之在米也，惟血气充足，运转迅急，若筛
米然运转不停、则糠 不混于米，而腾起浮聚，自作一团，血气充足周流，则毒不
滞于荣卫之中，而自然收敛以成疮，故痘疮及时贯脓，未尝烂肌损肉，只是将皮肉
红色毒瓦斯，收贮窠囊而已，其有日久才发臭烂者，此皆变证，而非本然如此也，今
举世以食物发痘，而不知其本无益也，惟服补气血药，以助其营运推出之势可也。
发热三日之后，热退身凉，大小不等，作三次出，淡红色如水珠光泽者，不须
服药。凡痘子出现，疏则毒轻，不可妄治，密则毒甚，却要磊落大小分明，不相
粘连，略与托里解毒之剂快斑汤、消毒饮、主之，使之易发易靥。如出太密，粘连
模糊，其毒尤甚，托里解毒之剂，宜多饮之，以防痒塌黑陷之变，更察外证，可
治则治，不可则勿治。凡痘子出形，皮肉如常，根苗明润，此毒轻也，不可妄治，
如皮肉昏黑或赤肿，根苗干枯青紫或灰白者，此毒甚也，以消毒饮、夺命丹、合服。
快 汤
人参（五分） 当归 防风 木通（各一钱） 甘草（三分） 木香 紫草 蝉蜕（各二分）
上锉细。水一盏，煎七分，去滓温服，不拘时。
消毒饮
牛蒡子 连翘 甘草 绿升麻 山豆根 紫草（各等分）
上，锉细。水一盏，煎七分，去滓温服，不拘时。
夺命丹
麻黄 升麻（各半两） 山豆根 红花子 大力子 连翘（各二钱半） 蝉蜕 紫草（各一钱半） 人中黄（三钱）
上，研细末。酒蜜和丸，辰砂为衣。薄荷叶煎汤下。
凡痘子之出，最要唇润舌润，红鲜如常，其毒则轻，如唇焦破裂，舌燥有芒，
为毒火太甚，表里郁遏，急宜解之，黄连解毒汤加大力子。
黄连解毒汤（烦躁）
发热时身体没有高热，腰、腹、脚、膝也不疼痛，过了三天才出现红点，且痘粒坚硬碍手，这是吉证（预后良好的病证），不需要服药。
发热时全身温热，不时发生惊厥，痘毒从心经发出，这也是吉证，可以治疗而痊愈。
按语：近年来，屡次有出痘前出现惊厥但最终凶险死亡的案例，好事不如无，不能说是吉证。
初起发热时，腹部剧烈疼痛，腰部像被棍棒打过一样，等到痘疹报形干燥后，之前的疼痛仍然不止的，死亡，无法治疗。
初起发热一天，遍身就出现红点，稠密得像蚕种，摸过去不碍手的，死亡，无法治疗。
初起发热时，头面部一片红如胭脂色的，六天后死亡。
初起发热时，用红纸捻蘸油点火，照心头皮肉里，红如一片胭脂，或者遍身都长成块状红色的，八九日后死亡。
痘疮的过程，始于见点（出现痘疹），从见点开始计算，期限止于七日，七日之内，就像花蕾刚开始绽放一样，其气日渐旺盛而透出，七日之后，气收敛而花谢了，所以服药者应当在七日之内，日夜连续服用，不要姑息纵容，以七日的辛苦，来保全百年的生命，人们不知道这个道理，只一味追求姑息，七日之外，服药就没有益处了。我曾说痘毒存在于血气之中，就像糠秕在米中一样，只有血气充足，运转迅速急切，像筛米一样运转不停，那么糠秕就不会混杂在米中，而是腾起浮聚，自己结成一团；血气充足周流全身，那么毒就不会滞留于营卫之中，而自然收敛形成疮疡，所以痘疮按时贯脓，未曾烂肌损肉，只是将皮肉的红色毒瓦斯收贮在窠囊而已，那些过了很久才发臭腐烂的，这些都是变证，而不是本来的样子。如今举世之人用食物来“发”痘，却不知道这原本没有益处，只有服用补气血的药物，来帮助其营运推出的势头就可以了。
发热三天之后，热退身凉，痘粒大小不等，分三次发出，颜色淡红如水珠光泽的，不需要服药。凡是痘子出现，稀疏则毒轻，不可胡乱治疗，稠密则毒重，却要磊落分明、大小清晰、互不粘连，略予托里解毒的方剂快斑汤、消毒饮来主治，使它们容易发出和结痂。如果出得太密，粘连模糊，其毒尤其严重，托里解毒的方剂，应当多饮用，以防出现痒塌黑陷的变证，更要观察外证，可治的就治，不可治的就不治。凡是痘子出形，皮肉如常，根苗明润，这是毒轻的表现，不可胡乱治疗，如果皮肉昏黑或赤肿，根苗干枯青紫或灰白的，这是毒重的表现，用消毒饮、夺命丹合服。
快斑汤
人参（五分） 当归 防风 木通（各一钱） 甘草（三分） 木香 紫草 蝉蜕（各二分）
以上锉细。水一盏，煎至七分，去渣温服，不拘时候。
消毒饮
牛蒡子 连翘 甘草 绿升麻 山豆根 紫草（各等分）
以上，锉细。水一盏，煎至七分，去渣温服，不拘时候。
夺命丹
麻黄 升麻（各半两） 山豆根 红花子 大力子 连翘（各二钱半） 蝉蜕 紫草（各一钱半） 人中黄（三钱）
以上，研成细末。酒蜜和丸，辰砂为衣。薄荷叶煎汤送下。
凡是痘子发出，最重要的是嘴唇润泽、舌头润泽，红润鲜艳如常，其毒则轻，如果嘴唇焦裂，舌燥有芒刺，为毒火太甚，表里郁遏，急宜解之，用黄连解毒汤加大力子。
When fever occurs, the body does not have high heat, and the waist, abdomen, feet, and knees do not pain. After three days, red spots appear, which are hard and obstructive to touch; this is a favorable prognosis (a condition with good outcome), and no medicine is needed.
During fever, the whole body feels warm, and there are occasional convulsions; the smallpox toxin emerges from the Heart Meridian, which is also a favorable prognosis, treatable and curable.
Note: In recent years, there have been frequent cases of convulsions before smallpox eruption leading to fatal outcomes; it is better not to call it favorable.
At the initial stage of fever, severe abdominal pain occurs, and the waist feels as if beaten by a staff; when the pustules dry up after reporting their shape, if the previous pain still does not cease, death is inevitable and untreatable.
If abdominal pain occurs first and then stops, medicines that tonify Qi and Blood can be used to save the patient.
On the first day of initial fever, if red spots appear all over the body, dense like silkworm eggs, but smooth to touch without obstruction, death is inevitable and untreatable.
At the initial stage of fever, if the head and face are uniformly red like rouge, death will occur on the sixth day.
At the initial stage of fever, if lighting a red paper wick dipped in oil and shining it on the scalp over the heart reveals redness like a patch of rouge inside the skin and flesh, or if the whole body forms clumps of redness, death will occur after eight or nine days.
The course of smallpox begins with the appearance of spots. Counting from the appearance of spots, the period lasts seven days. Within these seven days, it is like a flower bud beginning to bloom; its vital energy increases daily to emerge. After seven days, the energy condenses and the flower fades. Therefore, those taking medicine should take it continuously day and night within the seven-day period, without indulgence. The hardship endured for seven days ensures a lifetime of health. People do not understand this and only seek indulgence; after seven days, taking medicine is of no benefit. I once said that the smallpox toxin residing in Qi and Blood is like bran in rice. Only when Qi and Blood are sufficient and move swiftly and urgently, like sifting rice without stopping, will the bran not mix with the rice but rise and gather into a lump. When Qi and Blood are sufficient and circulate throughout the body, the toxin will not stagnate in the Ying and Wei levels but will naturally condense to form sores. Thus, smallpox suppurates on time without rotting muscle or damaging flesh; it merely stores the red toxic qi of the skin and flesh in the follicles. Those that become foul and rotten after a long time are all altered conditions, not the original state. Nowadays, the world uses food to "trigger" smallpox, unaware that this is originally unhelpful. It is only appropriate to take medicines that tonify Qi and Blood to assist the momentum of circulation and expulsion.
After three days of fever, if the heat subsides and the body becomes cool, with pustules of varying sizes emerging in three batches, pale red with a luster like water droplets, no medicine is needed. Whenever smallpox spots appear, if sparse, the toxin is light, and one must not treat rashly; if dense, the toxin is severe, yet they should be distinct, clear in size, and non-adherent. Slightly administer formulas that support the interior and resolve toxicity, such as Kuaiban Tang (Rapid Spot-Dispersing Decoction) and Xiaodu Yin (Toxin-Resolving Drink), to facilitate easy eruption and crusting. If eruption is too dense, adherent and blurred, the toxin is particularly severe; the interior-supporting and toxin-resolving formulas should be taken in larger quantities to prevent complications like itching, collapse, black depression, or sinking. Furthermore, observe external signs; treat if treatable, do not treat if not. When smallpox spots erupt, if the skin and flesh are normal, and the roots and tips are bright and moist, the toxin is light, and one must not treat rashly. If the skin and flesh are dull black or red-swollen, and the roots and tips are dry, purple-black, or grayish-white, the toxin is severe; combine Xiaodu Yin (Toxin-Resolving Drink) and Duoming Dan (Life-Snatching Pill).
Kuaiban Tang (Rapid Spot-Dispersing Decoction)
Ren Shen (Ginseng Radix et Rhizoma, 5 fen), Dang Gui (Angelicae Sinensis Radix), Fang Feng (Saposhnikoviae Radix), Mu Tong (Akebiae Caulis, each 1 qian), Gan Cao (Licorice Root, 3 fen), Mu Xiang (Aucklandiae Radix), Zi Cao (Arnebiae Radix seu Lithospermi Radix), Chan Tui (Cicadae Periostracum, each 2 fen).
Crush finely. Add one cup of water, decoct to七分 (70%), remove dregs, and take warm at any time.
Xiaodu Yin (Toxin-Resolving Drink)
Niu Bang Zi (Arctii Fructus), Lian Qiao (Forsythiae Fructus), Gan Cao (Licorice Root), Lv Sheng Ma (Green Cimicifugae Rhizoma), Shan Dou Gen (Sophorae Tonkinensis Radix), Zi Cao (Arnebiae Radix seu Lithospermi Radix, equal parts).
Crush finely. Add one cup of water, decoct to七分 (70%), remove dregs, and take warm at any time.
Duoming Dan (Life-Snatching Pill)
Ma Huang (Ephedrae Herba), Sheng Ma (Cimicifugae Rhizoma, each half liang), Shan Dou Gen (Sophorae Tonkinensis Radix), Hong Hua Zi (Carthami Flos), Da Li Zi (Arctii Fructus), Lian Qiao (Forsythiae Fructus, each 2.5 qian), Chan Tui (Cicadae Periostracum), Zi Cao (Arnebiae Radix seu Lithospermi Radix, each 1.5 qian), Ren Zhong Huang (Human Excrement Extract, 3 qian).
Grind into fine powder. Form pills with wine and honey, coat with Chen Sha (Cinnabar). Take with decoction of Bo He Ye (Menthae Haplocalycis Folium).
In the eruption of smallpox, the most important sign is moist lips and tongue, red and fresh as usual, indicating light toxin. If lips are scorched and cracked, and the tongue is dry with prickles, it indicates excessive fire toxin and internal-external stagnation; immediate resolution is required using Huanglian Jiedu Tang (Coptis Decoction for Resolving Toxins) plus Da Li Zi (Arctii Fructus).
Huanglian Jiedu Tang (Coptis Decoction for Resolving Toxins) [Indicated for restlessness]