巢氏云∶人聚蛇虫杂类，以器皿盛之，令相啖食，余一存者，即名为蛊，能变
化，或随饮食入腹，食人五脏。小儿有中者，病状与大人老子无异，则心腹刺痛懊
闷，急者即死，缓者涉历岁月，渐深羸困，食心脏尽，利血，心脏烂乃至死，死又
疰易旁人，故为蛊疰也。
《外台·范汪》疗大人小儿蛊疰百病， 瘕积聚，酸削骨肉，大小便不利，卒忤，遇
恶风，胪胀腹满淋水，转相注，殚门尽户，延及男女外孙，医所不能疗。更生
十七物紫参丸方
紫参 人参 半夏（汤洗） 藜芦 代赭石 桔梗 白薇 肉苁蓉（各三分） 石膏 大黄
牡蛎（熬） 丹参（各一分） 虾蟆（烧灰） 乌头（炮。各四分） 野狼毒（七分） 附子（炮，五分） 巴豆（七十
枚，去心皮，熬）
上件药捣筛，蜜和为丸。以饮下如小豆一丸，日三服，老小以意减之。蜂虿所
螫，以涂其上，神良。忌猪羊肉冷水。一方，无虾蟆，有干姜四分。
《圣惠》羚羊角散 治小儿中蛊，腹内坚如石，面目青黄，小便淋沥，变易无常。
羚羊角（屑） 荷（各一两） 栀子仁（七枚） 赤芍药 牡丹皮 黄连（去须。各一分） 犀角（屑半两）
上件药捣，粗罗为散。每服一钱，以水一小盏，煎至五分，去滓温服，日三四服，更量儿大小加减。
又方
败鼓皮（三分，炙令黄） 苦参（锉） 荷根（各一两）
上件药捣，粗罗为散，每服一钱，以水一小盏，煎至五分，去滓温服，日三四
服，更量儿大小，加减服之。
升麻散 治小儿国中蛊毒。
川升麻 桔梗（去芦头） 栝蒌根（各半两）
上捣，罗为粗散。每服一钱，以水一小盏，煎至五分，去滓温服，日四五服，量儿大小加减。
雄黄散 治小儿飞蛊，状如鬼气者，宜服。
雄黄 麝香（各细研） 犀角（末。各半两）
上件药，都研令匀。每服，以温水调下半钱匕，日四五服，量儿大小加减。
治小儿五种蛊毒悉主之方
上捣马兜铃根，细罗为散，每服一钱，以水一小盏，煎五分，去滓空腹顿服。
当时随吐蛊出，未快吐，即再服。
又方 上用败鼓皮一片，烧灰，细研为粉，空心，以粥饮调服一钱。病患须臾当呼
蛊主姓名，病便愈。
又方 上用荠 一两，捣罗为末，以粥饮调下一钱，甚效，量儿大小，加减服之。
治小儿畏忌中蛊欲死方
上用甘草半两生锉，以水一中盏，煎至五分，去滓，分为二服。当吐蛊出，若
平生预防蛊者，宜熟炙甘草煮汁服之，即内消不吐，神效。
治小儿中蛊毒，令腹内坚痛，面目青黄，淋露骨立，病变无常方
上用桃株寄生二两，捣细罗为散，如茶点服之，日四五服。
又方 上用麝香半钱，细研，空腹以温水调服。即吐出蛊毒未效，再服。
治小儿中蛊下血欲死方
上取生赤雌鸡翅下血，服之立效。
又方
上捣青蓝汁，频频与半合服。
《婴孺》雄黄丸 治小儿疰病，诸蛊魅精气入心入腹刺痛，黄瘦骨立。
雄黄 雌黄（各四分） 丹砂 野丈人 徐长卿（各三分） 大黄（五分） 麝香（三枣大） 羚羊角（屑，五分）
上为末，以青羊脂和丸。百日儿酒服黍大三丸，日进二服，或豆大，亦可。
〔张涣〕雄麝散 专治蛊毒病。
雄黄（水磨者，细研） 麝香（别研） 羚羊角（屑） 赤芍药 败鼓皮（炙黄。各一两） 马兜铃根 荠
鬼臼（去毛，各半两。以上除雄黄、麝香外，捣罗为细末）
上件八味，都一处拌匀研细。每服半钱，浓煎甘草汤调下，食前。
麝犀汤
犀角屑 鬼箭 安息香 水磨雄黄（细研。各一两） 苦参 牡丹皮（各半两） 以上捣，罗为细末，次用
麝香（半两，细研）
上件都拌匀。每服一钱，水一大盏，煎至五分，去滓放温，时时服。
巢元方说：人们将蛇、虫等杂类聚集在一起，用器皿盛放，让它们互相吞食，最后剩下的那一只，就称为“蛊”。它能变化形态，有时随着饮食进入人体腹部，吞噬人的五脏。小儿如果中了蛊毒，病症表现与成人没有不同，会出现心腹刺痛、烦闷懊恼的症状。病情急骤的会立即死亡；病情缓慢的则历经岁月，逐渐消瘦困顿，直到心脏被吃尽，排出血液，心脏腐烂直至死亡。死后，这种病邪又会传染给旁人，所以称为“蛊疰”（具有传染性的蛊毒）。
《外台秘要》引用范汪的记载，治疗成人和小儿的蛊疰百病，以及瘕聚积聚、肌肉消瘦、大小便不通、突然受惊忤逆、遭遇恶风、身体肿胀腹部胀满如淋水状、相互传染、满门患病、延及男女外孙，这是医生难以治愈的疾病。列出“更生十七物紫参丸”方剂：
紫参、人参、半夏（汤洗）、藜芦、代赭石、桔梗、白薇、肉苁蓉（各三分）、石膏、大黄、牡蛎（熬制）、丹参（各一分）、虾蟆（烧成灰）、乌头（炮制，各四分）、野狼毒（七分）、附子（炮制，五分）、巴豆（七十枚，去心皮，炒制）。
以上药物捣碎过筛，用蜂蜜调和制成丸药。每次服用像小豆大的一丸，用水送服，每日三次，老人和小孩根据情况减量。被蜂蝎蜇伤，涂抹此药在患处，效果极佳。忌食猪羊肉和冷水。另一版本，没有虾蟆，有四分干姜。
《太平圣惠方》羚羊角散：治疗小儿中蛊，腹部坚硬如石头，面目青黄，小便淋漓不畅，病情变化无常。
羚羊角（锉屑）、荷叶（各一两）、栀子仁（七枚）、赤芍药、牡丹皮、黄连（去须，各一分）、犀角（锉屑，半两）。
以上药物捣碎，粗罗为散剂。每次服用一钱，用水一小盏，煎至五分，去渣温服，每日三四次，再根据患儿年龄大小增减剂量。
又一方：
败鼓皮（三分，炙至黄色）、苦参（锉碎）、荷根（各一两）。
以上药物捣碎，粗罗为散剂，每次服用一钱，用水一小盏，煎至五分，去渣温服，每日三四次，再根据患儿年龄大小增减剂量。
升麻散：治疗小儿国内感染的蛊毒。
川升麻、桔梗（去芦头）、栝蒌根（各半两）。
以上捣碎，罗为粗散。每次服用一钱，用水一小盏，煎至五分，去渣温服，每日四五次，根据患儿年龄大小增减剂量。
雄黄散：治疗小儿飞蛊，症状类似鬼气侵扰者，适宜服用。
雄黄、麝香（各细研）、犀角（末，各半两）。
以上药物，一起研磨均匀。每次服用，用温水调下半钱匕，每日四五次，根据患儿年龄大小增减剂量。
治疗小儿五种蛊毒都主治的方剂：
以上捣碎马兜铃根，细罗为散剂，每次服用一钱，用水一小盏，煎五分，去渣空腹顿服。当时随呕吐出蛊毒，如果未完全吐出，就再次服用。
又一方：用上方的败鼓皮一片，烧成灰，细研为粉，空腹时，用米汤调服一钱。病患片刻后会呼喊蛊主的姓名，病就好了。
又一方：用上方的荠菜一两，捣罗为末，用米汤调下一钱，效果很好，根据患儿年龄大小，增减剂量服用。
治疗小儿畏惧忌惮中蛊欲死的方剂：
上方取生甘草半两，生锉，用水一中盏，煎至五分，去渣，分为两次服用。应当吐出蛊毒，如果是平时预防蛊毒的人，适宜用熟炙甘草煮汁服用，这样会在体内消散而不呕吐，效果神妙。
治疗小儿中蛊毒，导致腹部坚硬疼痛，面目青黄，淋露骨立，病变无常的方剂：
上方取桃树寄生二两，捣细罗为散剂，像喝茶点那样服用，每日四五次。
又一方：上方取麝香半钱，细研，空腹用温水调服。如果吐出蛊毒无效，再次服用。
治疗小儿中蛊下血欲死的方剂：
上方取生赤雌鸡翅下的血，服用后立即见效。
又一方：
上方捣取青蓝汁，频频给予半合服用。
《婴孺书》雄黄丸：治疗小儿疰病，各种蛊魅精气进入心脏和腹部引起刺痛，面色萎黄，瘦骨嶙峋。
雄黄、雌黄（各四分）、丹砂、野丈人、徐长卿（各三分）、大黄（五分）、麝香（三颗枣大小）、羚羊角（屑，五分）。
以上制成末，用青羊脂调和制成丸药。百日大的婴儿用酒送服黍米大小的三丸，每日进服两次，或者做成豆子大小也可以。
〔张涣〕雄麝散：专门治疗蛊毒病。
雄黄（水磨者，细研）、麝香（另研）、羚羊角（屑）、赤芍药、败鼓皮（炙黄，各一两）、马兜铃根、荠菜、鬼臼（去毛，各半两。以上除雄黄、麝香外，捣罗为细末）。
以上八味药，放在一起拌匀研细。每次服用半钱，浓煎甘草汤调下，饭前服用。
麝犀汤：
犀角屑、鬼箭羽、安息香、水磨雄黄（细研，各一两）、苦参、牡丹皮（各半两。以上捣，罗为细末，其次用麝香半两，细研）。
以上全部拌匀。每次服用一钱，用水一大盏，煎至五分，去渣放温，时时服用。
Chao Yuanfang stated: People gather various snakes and insects together, place them in vessels, and allow them to devour each other. The one remaining is named "Gu" (a venomous insect created by mutual cannibalism). It can transform its form and may enter the human abdomen through food or drink, consuming the five zang organs. Children who contract Gu exhibit symptoms identical to adults, including stabbing pain in the heart and abdomen, restlessness, and mental anguish. In acute cases, death occurs immediately; in chronic cases, it persists for years, leading to gradual emaciation and debility until the heart is consumed, bloody stools are passed, and the heart rots, resulting in death. After death, the pathogenic factor transmits to others, hence it is called "Gu Zhu" (infectious Gu disease).
The *Waitai Miyao* cites Fan Wang's records for treating Gu Zhu and hundred diseases in both adults and children, as well as accumulations and masses (*jia ji*), severe muscle wasting, difficulty in urination and defecation, sudden fright and counterflow, exposure to malignant wind, abdominal distension resembling water accumulation, mutual transmission, affecting entire households, extending to male and female grandchildren, conditions deemed incurable by physicians. The formula "Gengsheng Seventeen-Ingredient Zishan Pill" is prescribed:
Zishan (Radix Codonopsis), Renshen (Radix Ginseng), Banxia (Rhizoma Pinelliae Praeparatum, washed with decoction), Lilu (Radix Veratri), Daizheshi (Haematitum), Jiegeng (Radix Platycodonis), Baiwei (Cortex Cynanchi Atrati), Rongcongrong (Herba Cistanches), each 3 fen; Shigao (Gypsum Fibrosum), Dahuang (Radix et Rhizoma Rhei), Muli (Concha Ostreae, processed), Danshen (Radix Salviae Miltiorrhizae), each 1 fen; Xima (Bufo bufo gargarizans, burnt to ash), Wutou (Radix Aconiti Lateralis Preparata), each 4 fen; Yelangdu (Radix Stellerae Chamaejasme), 7 fen; Fuzi (Radix Aconiti Lateralis Preparata), 5 fen; Badou (Semen Crotonis Tiglii, 70 seeds, dehearted and deskinning, roasted).
Crush and sieve the above herbs, mix with honey to form pills. Administer one pill the size of a small bean with water, three times daily. Dosage for elderly and children should be reduced according to circumstances. For stings from bees or scorpions, apply topically to the affected area; this is highly effective. Avoid pork, mutton, and cold water. An alternative version excludes Xima but includes Ganjiang (Rhizoma Zingiberis Recens) 4 fen.
Taiping Shenghui Fang Lingyangjiao San: Treats pediatric Gu, characterized by an abdomen hard as stone, cyanotic and yellow complexion, dribbling urine, and unpredictable symptom variations.
Lingyangjiao (Cornu Saigae Tataricae, sliced), He Ye (Folium Nelumbinis), each 1 liang; Zhizi Ren (Semen Gardeniae), 7 pieces; Chi Shaoyao (Radix Paeoniae Rubra), Mudanpi (Cortex Moutan), Huanglian (Rhizoma Coptidis, de-stamened), each 1 fen; Xijiao (Cornu Rhinocerotis, sliced), 0.5 liang.
Crush the above herbs and sieve into a coarse powder. Take 1 qian per dose, decoct with one small cup of water until reduced to half a cup, strain, and take warm. Three to four times daily. Adjust dosage based on the child's age and size.
Another prescription:
Baigupi (Corium Corii Asini Usturn, 3 fen, roasted until yellow), Kushen (Radix Sophorae Flavescentis, crushed), Gen Gen (Rhizoma Nelumbinis), each 1 liang.
Crush and sieve into a coarse powder. Take 1 qian per dose, decoct with one small cup of water until reduced to half a cup, strain, and take warm. Three to four times daily. Adjust dosage based on the child's age and size.
Shengma San: Treats Gu poison contracted within the region.
Chuan Shengma (Radix Cimicifugae), Jiegeng (Radix Platycodonis, de-rhizome), Gualougen (Radix Trichosanthis), each 0.5 liang.
Crush and sieve into a coarse powder. Take 1 qian per dose, decoct with one small cup of water until reduced to half a cup, strain, and take warm. Four to five times daily. Adjust dosage based on the child's age and size.
Xionghuang San: Treats flying Gu in children, presenting like ghostly qi invasion.
Xionghuang (Realgar), Shexiang (Moschus), each finely ground; Xijiao (Cornu Rhinocerotis, powdered), each 0.5 liang.
Grind all ingredients uniformly. Take half a qian bi (spoonful) mixed with warm water per dose, four to five times daily. Adjust dosage based on the child's age and size.
Formula for treating all five types of Gu poison in children:
Crush Madouling Gen (Radix Aristolochiae Manshuriensis), sieve into a fine powder. Take 1 qian per dose, decoct with one small cup of water for five minutes, strain, and take on an empty stomach in one go. The Gu should be vomited out immediately. If vomiting is incomplete, administer again.
Another prescription: Take one piece of Baigupi (Corium Corii Asini Usturn), burn to ash, grind into fine powder. Take 1 qian mixed with rice broth on an empty stomach. The patient will soon call out the name of the Gu master, and the illness will resolve.
Another prescription: Take Yi Cai (Herba Portulacae Oleraceae) 1 liang, grind into powder. Take 1 qian mixed with rice broth. This is very effective. Adjust dosage based on the child's age and size.
Formula for pediatric fear and impending death due to Gu:
Take raw Gancao (Radix Glycyrrhizae Uralensis) 0.5 liang, freshly crushed. Decoct with one medium cup of water until reduced to half a cup, strain, and divide into two doses. Gu should be vomited out. For preventive measures against Gu, use roasted Gancao boiled in water; this causes internal resolution without vomiting and is miraculous.
Formula for pediatric Gu poison causing abdominal hardness and pain, cyanotic-yellow complexion, emaciation, and variable symptoms:
Take Tao Zhu Ji Sheng (Viscum Coloratum growing on Peach Tree) 2 liang, crush and sieve into a fine powder. Take like tea infusion, four to five times daily.
Another prescription: Take Shexiang (Moschus) 0.5 qian, finely ground. Take mixed with warm water on an empty stomach. If vomiting Gu poison is ineffective, administer again.
Formula for pediatric Gu causing hematochezia and impending death:
Take blood from under the wing of a raw red female chicken. Take orally for immediate effect.
Another prescription:
Crush Qinglan Zhi (Indigo Naturalis juice), administer half he frequently.
Yingru Shu Xionghuang Wan: Treats pediatric Zhu disease, where Gu and demonic essences enter the heart and abdomen causing stabbing pain, sallow complexion, and emaciation.
Xionghuang (Realgar), Cihuang (Orpiment), each 4 fen; Danzha (Cinnabaris), Yezhangren (Radix Astragali Complanati), Xuchangqing (Herba Cynanchi Paniculati), each 3 fen; Dahuang (Radix et Rhizoma Rhei), 5 fen; Shexiang (Moschus), size of three jujubes; Lingyangjiao (Cornu Saigae Tataricae, sliced), 5 fen.
Grind into powder, mix with fat from a black ram to form pills. Infants aged 100 days take three pills the size of millet grains with wine, twice daily. Pills the size of beans are also acceptable.
[Zhang Huan] Xiongshi San: Specifically treats Gu poison disease.
Xionghuang (Realgar, water-ground and finely ground), Shexiang (Moschus, separately ground), Lingyangjiao (Cornu Saigae Tataricae, sliced), Chi Shaoyao (Radix Paeoniae Rubra), Baigupi (Corium Corii Asini Usturn, roasted yellow), each 1 liang; Madouling Gen (Radix Aristolochiae Manshuriensis), Yi Cai (Herba Portulacae Oleraceae), Guijiu (Radix Podophylli Emodi, de-hairy), each 0.5 liang. (All except Xionghuang and Shexiang are crushed and sieved into fine powder).
Mix all eight ingredients thoroughly and grind finely. Take 0.5 qian per dose, mixed with concentrated decoction of Gancao (Radix Glycyrrhizae Uralensis), taken before meals.
Shexi Tang:
Xijiao Xie (Cornu Rhinocerotis, sliced), Guijian Yu (Ramulus Corni Swinhoei), Anxi Xiang (Benzoinum), Shuimo Xionghuang (Realgar, water-ground and finely ground), each 1 liang; Kushen (Radix Sophorae Flavescentis), Mudanpi (Cortex Moutan), each 0.5 liang. (These are crushed and sieved into fine powder). Then add Shexiang (Moschus) 0.5 liang, finely ground.
Mix all ingredients thoroughly. Take 1 qian per dose, decoct with one large cup of water until reduced to half a cup, strain, let cool to warm temperature, and take occasionally.