〔薛〕 多骨疽者，由疮疡久溃，气血不能营于患处，邪气陷袭，久则烂筋腐骨而脱
出，属足三阴亏损之症也。用补中益气汤以固根本。若阴火发热者，佐以六味丸，壮水
之主以镇阳光。阳气虚寒者，佐以八味丸，益火之源以消阴翳。外以附子饼、葱熨法祛散
寒邪，补接荣气，则骨自脱疮自敛也。夫肾主骨，若肾气亏损，其骨渐肿，荏苒岁月溃
而出骨，亦用前法。若投以克伐之剂，复伤真气，鲜有不误者。 举人于廷器，腿患流
注年余，出腐骨少许，午前畏寒，午后发热，口干唾痰，小便频数，予以为足三阴亏损，朝
用补中益气汤，夕用六味丸料加黄 、当归、五味子，各三十余剂，外用豆豉饼，诸症渐
愈，又以十全大补之类，喜其慎疾而愈。
一儒者患附骨疽，失于调补，疮口不敛，日出清脓少许，已而常出三腐骨，其脉但数而
无邪，此所血虚，疮结脓管而不能愈。 以乌金膏，日服十全大补汤而愈。 上舍王廷
璋患前症，三年未愈，肢体消瘦，饮食难化，手足并冷，大便不通，手足阴冷。予谓此阳
气虚寒，用补中益气汤、八味丸，仍灸其患处而痊。 一男子，上 肿硬年余方溃，内
热作渴，肢体消瘦，六脉洪大，左手尤甚。用补中益气汤、六味丸出腐骨一块，仍服前药，
诸症悉去，疮口亦敛。 一男子十六岁，足间肿黯，溃而露骨，体瘦盗汗，发热口干，用
十全大补汤、六味地黄丸，各五十余剂而愈。不然，多变瘵 ，或沥尽气血而亡。 一男
子，自十四岁闪足肿痛，服流气饮，外敷寒凉腐溃而至十六，疮口张开，足背漫肿黯黑，
骨露出，形体消瘦，盗汗不止，发热口舌干燥，天真已丧。用十全大补汤、六味地黄丸，
各五十余剂，元气渐复，患处渐赤，脱落骨一块，又各五十余剂始愈。 一妇人年三十
余，素弱，左手背渐肿，二年后溃，出清脓，肿黯连臂，内热晡热，自汗盗汗，经水两月
一至，此肝脾气血亏损。朝用归脾汤，夕用逍遥散，肿处频用葱熨法，两月余诸症渐愈，
疮出腐骨，仍服前药，前后共三百余剂得愈。
【薛己】多骨疽，是由于疮疡长期溃烂，气血无法滋养患处，邪气乘虚深入，日久导致筋烂骨腐而脱落排出，属于足三阴经亏损的病证。治疗应用补中益气汤来巩固根本。如果伴有阴火发热，可配合使用六味丸，通过壮水之主（滋补肾阴）来抑制亢盛的阳热。如果是阳气虚弱寒盛，可配合使用八味丸，通过益火之源（温补肾阳）来消除阴寒之邪。外用附子饼、葱熨法以驱散寒邪，补充接引营卫之气，则骨骼自然脱落，疮口自然愈合。肾主司骨骼，若肾气亏损，骨骼逐渐肿胀，经过漫长岁月后溃破排出死骨，也采用上述方法。如果误用攻伐克削的药物，再次损伤真气，很少有不酿成祸患的。
举人于廷器，腿部患有流注病一年多，排出少许腐骨，午前畏寒，午后发热，口干且唾吐痰液，小便频数。我认为是足三阴经亏损，早晨服用补中益气汤，晚上服用六味丸料加黄柏、当归、五味子，各服用三十余剂，外用豆豉饼敷贴，各种症状逐渐痊愈，后又服用十全大补汤之类的方剂，因其谨慎调养疾病而治愈。
一位儒生患有附骨疽，因未能及时调补，疮口不收敛，每天流出少量清稀脓液，随后经常排出三块腐骨，其脉象仅快而无外邪之象，这是血虚所致，疮口结成脓管而不能愈合。使用乌金膏外敷，每日内服十全大补汤而痊愈。
上舍王廷璋患前症，三年未愈，肢体消瘦，饮食难以消化，手足冰冷，大便不通，手足阴冷。我认为这是阳气虚弱寒盛，使用补中益气汤、八味丸，并仍灸患处而痊愈。
一名男子，小腿部位肿硬一年多才溃破，内有热感且作渴，肢体消瘦，六脉洪大，左手脉象尤为明显。使用补中益气汤、六味丸排出腐骨一块，继续服用前方，各种症状全部去除，疮口也愈合了。
一名十六岁男子，足部肿胀色暗，溃破后露出骨头，身体瘦弱且有盗汗，发热口干，使用十全大补汤、六味地黄丸，各服用五十余剂而痊愈。否则，病情多变成为痨瘵（消耗性疾病），或耗竭气血而死亡。
一名男子，自十四岁时闪挫导致足部肿痛，服用流气饮，外敷寒凉药物导致腐烂溃破，直到十六岁，疮口张开，足背漫肿色暗黑，骨头露出，形体消瘦，盗汗不止，发热口舌干燥，先天真元已丧失。使用十全大补汤、六味地黄丸，各服用五十余剂，元气逐渐恢复，患处逐渐变红，脱落一块骨头，又各服用五十余剂始得痊愈。
一名三十多岁的妇人，素体虚弱，左手背逐渐肿胀，两年后溃破，流出清稀脓液，肿胀色暗连及手臂，内有热感且傍晚发热，自汗盗汗，月经两个月来一次，这是肝脾气血亏损。早晨服用归脾汤，晚上服用逍遥散，肿胀处频繁使用葱熨法，两个多月各种症状逐渐痊愈，疮口排出腐骨，仍服用前方，前后共三百余剂得以痊愈。
[Xue Ji] Duogu Ju (Bone-Exuding Abscess) arises from chronic ulceration of sores, where Qi and Blood fail to nourish the affected area. Pathogenic factors sink and invade; over time, tendons rot and bones decay, eventually shedding and discharging. This condition belongs to deficiency syndromes of the Three Yin meridians of the foot. Treatment should employ Buzhong Yiqi Tang (Tonify the Middle and Augment the Qi Decoction) to consolidate the root. If accompanied by Yin-fire fever, it should be assisted with Liuwei Wan (Six-Ingredient Pill with Rehmannia), strengthening the master of Water (nourishing Kidney Yin) to suppress excessive Yang heat. In cases of Yang Qi deficiency and cold, it should be assisted with Bawei Wan (Eight-Ingredient Pill with Rehmannia), benefiting the source of Fire (warming Kidney Yang) to dissipate Yin shadows. Externally, Fuzi Bing (Aconite Cake) and Cong Yi Fa (Scallion Moxibustion/Warming Method) are used to dispel cold pathogens and supplement and connect Ying Qi (Nutritive Qi); then the bone will naturally shed and the sore will naturally close. The Kidney governs the bones; if Kidney Qi is deficient, the bones gradually swell, and after a long passage of time, they ulcerate and discharge dead bone. The aforementioned methods should also be used here. If attacking and reducing agents are administered, further injuring the True Qi, few cases will not go awry.
The Scholar Yu Tingqi suffered from Liuzhu (Flowing Abscess) in his leg for over a year, expelling a small amount of necrotic bone. He experienced chills before noon, fever after noon, dry mouth with spitting of phlegm, and frequent urination. I diagnosed this as a deficiency of the Three Yin meridians of the foot. In the morning, he took Buzhong Yiqi Tang; in the evening, he took Liuwei Wan formula added with Huangbai (Phellodendri Cortex), Danggui (Angelicae Sinensis Radix), and Wuweizi (Schisandrae Fructus). After taking each prescription for more than thirty doses, and using Douchi Bing (Fermented Soybean Cake) externally, all symptoms gradually improved. He subsequently took formulas similar to Shiquan Dabu Tang (Perfect Golden Great Tonifying Decoction). Because he was cautious in managing his illness, he recovered.
A Confucian scholar suffered from Fugu Ju (Bone-Adhering Abscess). Due to a lack of timely regulation and tonification, the sore did not heal, discharging a small amount of clear pus daily. Later, three pieces of necrotic bone were frequently discharged. His pulse was rapid but without pathogenic signs, indicating Blood deficiency causing the sore to form a sinus tract that could not heal. He was treated with Wujin Gao (Black Gold Ointment) externally and Shiquan Dabu Tang internally once daily, resulting in recovery.
Shangshe Wang Tingzhang suffered from the aforementioned condition for three years without healing. His limbs were emaciated, food digestion was difficult, hands and feet were cold, and bowel movements were obstructed, with coldness in the Yin aspects of hands and feet. I determined this to be Yang Qi deficiency and cold. He was treated with Buzhong Yiqi Tang and Bawei Wan, along with moxibustion applied to the affected area, leading to recovery.
A man had swelling and hardness in his lower leg for over a year before ulceration. He felt internal heat and thirst, his limbs were emaciated, and his six pulses were surging and large, especially on the left hand. He was treated with Buzhong Yiqi Tang and Liuwei Wan, which expelled a piece of necrotic bone. Continuing the previous medications, all symptoms disappeared, and the sore closed.
A sixteen-year-old man had swelling and dark discoloration in his foot. After ulceration, bone was exposed. He was thin with night sweats, fever, and dry mouth. He was treated with Shiquan Dabu Tang and Liuhuang Dihuang Wan (Six-Ingredient Pill with Rehmannia), taking each for more than fifty doses, resulting in recovery. Otherwise, the condition might have transformed into Zhai (Consumption/Tuberculosis) or led to death due to exhaustion of Qi and Blood.
A man suffered from sprain-induced swelling and pain in his foot starting at age fourteen. He took Liuqi Yin (Flowing Qi Decoction) and applied cold-natured herbs externally, leading to rotting and ulceration. By age sixteen, the sore opened, with diffuse swelling and dark black discoloration on the dorsum of the foot, bone exposure, emaciation, incessant night sweats, fever, and dry mouth and tongue. His innate vitality was lost. He was treated with Shiquan Dabu Tang and Liuhuang Dihuang Wan, taking each for more than fifty doses. His Yuan Qi (Original Qi) gradually recovered, the affected area gradually turned red, and one piece of bone detached. After another fifty doses of each, he finally recovered.
A woman in her thirties, constitutionally weak, had gradual swelling on the back of her left hand. Two years later, it ulcerated, discharging clear pus. The swelling and dark discoloration extended to her arm. She experienced internal heat and afternoon fever, spontaneous sweating, and night sweats, with menstruation occurring only once every two months. This indicated Liver and Spleen Qi and Blood deficiency. In the morning, she took Guipi Tang (Restore the Spleen Decoction); in the evening, she took Xiaoyao San (Free and Easy Wanderer Powder). The swollen area was frequently treated with Cong Yi Fa (Scallion Moxibustion/Warming Method). After more than two months, all symptoms gradually improved. The sore discharged necrotic bone, and she continued the previous medications. A total of more than three hundred doses were taken before full recovery.