味苦，性寒无毒，入心肺大小肠胃膀胱六经。主五内邪热，亡血津枯，面红目赤，痈肿
疮疡，五种黄病，开郁泻火，疗心中懊 颠倒而不眠，治脐下血滞小便而不利。皮走肌肤之
热，仁去心胸之热，解羊踯躅及 虫毒。
按∶山栀味苦归心，轻飘象肺，入肠则供肺为传道者也，小肠受盛与心应者也，胃亦上
焦之腑也，膀胱亦肺部之约也，故咸入之，以理邪热诸证。洁古曰∶轻清上行。丹溪又曰∶
屈曲下行。两家之说，似相左矣。不知惟其上行，最能清肺，肺气清而化，则小便从此气化
而出。经曰∶膀胱藏津液，气化则能出者，是也。虚火炎者，炒黑用。烦郁呕逆者，姜汁炒
用，此外并宜生服。
雷公云∶凡使勿用颗大者，号曰伏。凡栀子无力，须要如雀脑并须长有九路，赤色者上。
凡使先去皮须取仁，以甘草水浸一宿，漉出焙干，捣筛如金末用。
味苦辛，性热有小毒，入肝脾胃大肠肾五经。主下气消痰，寒气噎塞，心腹刺痛，霍乱
转筋，香港脚攻心，止咳逆，逐风邪，消宿食，除血痹，盐汤炮去毒用。蓼实为使，恶丹参、
硝石、白垩，畏紫石英。
按∶吴茱萸辛热之剂，宜入五经，以理寒证。多食大损元气，肠虚者忌之。
雷公云∶凡使先去叶梗，并杂收子，用大盆二口，使盐水洗一百转，自然无涎，日干，
任入丸散中用。修事十两，用盐二两，研作末，投东流水，四投中分作一百度洗，则有大效。
若用醋煮
【山栀】
味苦，性寒，无毒，归心、肺、大肠、小肠、胃、膀胱六经。主治五脏内的邪热，失血导致的津液枯竭，面色红赤，眼睛发红，痈肿疮疡，五种黄病（指黄疸病的五种分类），能开郁结、泻火毒，治疗心中烦闷懊恼、颠倒不安且无法入睡的症状，治疗脐下气血瘀滞导致的小便不利。栀子皮能清除肌肤之热，栀子仁能清除心胸之热，能解羊踯躅（闹羊花）及虫蛇毒。
按语：山栀味苦归于心经，其质轻飘象应于肺经，进入肠道则作为肺的传导助手，小肠受盛化物与心经相应，胃也是上焦的腑脏，膀胱也是肺经的制约关联之处，所以都归于这些经络，以调理各种邪热证候。洁古（张元素）说：其性轻清上行。丹溪（朱震亨）又说：其性屈曲下行。两家的说法似乎相反。不知道正是因为其上行，最能清肺，肺气清肃则气化功能正常，小便因此通过气化而排出。《内经》说：膀胱贮藏津液，经过气化作用才能排出，说的就是这个道理。如果是虚火上炎者，炒黑后使用。如果是烦闷郁结、呕吐逆气者，用姜汁炒制后使用，其余情况都适宜生服。
雷公说：凡是使用时，不要用颗粒大的，那种叫做“伏”。凡是栀子药效无力，必须选用像雀脑一样小且长有九条棱纹、颜色赤红的为上品。凡是使用时，先去掉外皮取出仁，用甘草水浸泡一夜，捞出焙干，捣碎筛成金粉状使用。
【吴茱萸】
味苦辛，性热，有小毒，归肝、脾、胃、大肠、肾五经。主治降气消痰，寒气引起的噎塞感，心腹刺痛，霍乱转筋，脚气攻心，止咳逆，驱逐风邪，消化积食，消除血痹，用盐汤炮制以去除毒性。以蓼实为引药，厌恶丹参、硝石、白垩，畏惧紫石英。
按语：吴茱萸是辛热的药剂，适宜入这五经，以调理寒证。多吃会大损元气，肠道虚弱者忌用。
雷公说：凡是使用时，先去掉叶梗和杂质收取果实，用两个大盆，让盐水洗涤一百遍，自然就没有黏液了，晒干后，任入丸散剂中使用。修治十两药材，用盐二两，研成末，投入东流水中，分四次投掷搅拌共一百遍洗涤，则有显著疗效。如果用醋煮……
[Shanzhi (Gardeniae Fructus)]
Bitter in taste, cold in nature, non-toxic. Enters the Heart, Lung, Large Intestine, Small Intestine, Stomach, and Bladder meridians. It primarily treats pathogenic heat within the five zang organs, fluid depletion due to blood loss, redness of the face and eyes, carbuncles and sores, the five types of jaundice (Wuzhong Huangbing), opens depression, drains fire, treats mental restlessness and insomnia characterized by a feeling of stifling oppression in the chest, and treats difficulty in urination caused by blood stasis below the umbilicus. The peel clears heat from the skin and muscles, while the seed clears heat from the heart and chest; it resolves toxicity from *Rhododendron molle* (Yangzhizhu) and insect bites.
Commentary: Shanzhi is bitter and enters the Heart meridian; its light and floating nature corresponds to the Lung meridian. Upon entering the intestines, it serves as the transmission assistant for the Lung. The Small Intestine receives and transforms substances and corresponds to the Heart. The Stomach is also a fu organ of the Upper Jiao, and the Bladder is also constrained by the Lung meridian; thus, it enters all these meridians to regulate various pathogenic heat syndromes. Jiegu (Zhang Yuansu) stated: "Its nature is light, clear, and ascends." Danxi (Zhu Zhenheng) further stated: "It bends and descends." These two theories seem contradictory. However, it is precisely because it ascends that it can best clear the Lungs. When Lung Qi is clear and transforms properly, urine is excreted through qi transformation. As the Classics state: "The Bladder stores fluids; only through qi transformation can they be excreted." This refers to this mechanism. For deficiency fire flaring upward, use charred Shanzhi. For irritability, depression, vomiting, and counterflow, use ginger-juice fried Shanzhi; otherwise, raw administration is suitable.
Leigong said: When using, do not use large grains, which are called "Fu" (dormant/weak). Effective Shanzhi must resemble a sparrow's brain, be long with nine ridges, and have a reddish color, which is considered superior. When processing, first remove the peel and take out the seeds. Soak them in licorice water overnight, drain, dry by roasting, crush, and sieve into a golden powder for use.
[Wuzhuyu (Evodiae Fructus)]
Bitter and acrid in taste, hot in nature, slightly toxic. Enters the Liver, Spleen, Stomach, Large Intestine, and Kidney meridians. It primarily directs qi downward, resolves phlegm, treats dysphagia caused by cold qi, stabbing pain in the heart and abdomen, cholera with muscle spasms, foot disease attacking the heart, stops cough and counterflow, expels wind pathogens, digests retained food, and removes blood bi. It should be processed with salt water decoction to reduce toxicity. *Polygonum multiflorum* fruit (Liaoshi) is used as an adjuvant. It is incompatible with *Salvia miltiorrhiza* root (Danshen), Niter (Xiaoshi), and Kaolin (Baie); it fears Fluorite (Ziyingshi).
Commentary: Wuzhuyu is an acrid and hot agent, suitable for entering the five meridians to regulate cold syndromes. Excessive consumption severely damages primordial qi; it is contraindicated for those with weak intestines.
Leigong said: When processing, first remove leaves and stems, discard impurities, and collect the fruits. Use two large basins, wash with salt water one hundred times until the sticky substance naturally disappears. Sun-dry, then it can be freely used in pills and powders. To process ten taels of material, use two taels of salt, grind into powder, throw into flowing eastward water, stir four times over one hundred cycles of washing, which yields great efficacy. If boiled with vinegar...