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In cases where, after the resolution of smallpox and measles (Xiaozhen), the patient's movements and diet have returned to normal, sudden profuse sweating all over the body like water occurs, or death ensues solely due to severe colic in the heart and abdomen. This is because the primordial Qi (Yuanqi) remains deficient; although there appears to be no disease on the exterior, the interior is actually empty. Upon contracting the abnormal qi of epidemic pestilence, the righteous Qi fails to overcome the pathogenic factor. Death resulting from such poisoning is termed "Zhong E" (Acute Poisoning or Sudden Collapse). Occasionally, patients may regain consciousness by taking Ginseng Decoction with Suhexiang Wan, which is somewhat similar to adults suffering from sudden stroke due to deficiency.

Abscesses (Yong) occurring after smallpox are mostly located between bone joints, while residual toxins from measles often remain in the mouth and throat area. Why is this? The residual toxins of smallpox tend to linger in the Liver and Kidney, whereas the residual toxins of measles tend to linger in the Lung and Stomach. Therefore, in treating measles, one should initially employ the method of releasing the exterior (Jiebiao) to facilitate immediate eruption, followed by cooling methods to ensure easy resolution. Otherwise, if the toxin cannot fully reach the exterior initially, heat flows into the Heart, and toxicity becomes severe in the Spleen. With excessive Heart Fire blazing upward, it erupts at orifices and then subsides. If Yin-nourishing and clearing-resolving methods are not applied, minor heat transforms into major heat, and minor toxicity evolves into major toxicity. Toxin in the Fu organs belongs to Yang, blazes upward, emerges at the exterior, and is shallow; toxin in the Zang organs belongs to Yin, sinks downward, stagnates in the interior, and is deep. Since Zang and Fu, Yin and Yang differ, the pathways of bone marrow and skin/cuticle also diverge. One scenario involves sudden onset leading to eye diseases and oral ulcers; the other emerges from within the bones, transmits outside the vessels, shifts to the skin, and eventually ulcerates. Those occurring mostly in bone joints result from long-standing disease stagnation, uneven circulation of stagnant Qi, unsmooth blood flow, and toxin stagnation in the joints. Persistent coughing after measles is caused by excessive Heart Fire burning the Metal of the Lung; since the Lung constitution is naturally dry, dryness becomes even more severe here, causing prolonged coughing with rebellious Qi that cannot descend. Cases transforming into dysentery occur because the Lung and Large Intestine are exterior-interior pairs; the Lung receives the pathogen and transmits it to the Large Intestine.

When spots first appear on the head and face, then emerge on both cheeks, extending down to the feet, resembling mustard seeds in shape and peach blossoms in color, erupting completely in two or three waves, accompanied by calm spirit, harmonious diet, and regular urination and defecation, this indicates a favorable prognosis (Shun Hou). When spots on the head and face are fully erupted, granules are plump and numerous, pale red and moist, and gradually fade after three days, the condition is mild.