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When the disease is deep-seated but the medication is superficial, it ultimately yields no effect; when the disease is mild but the medication is profound, it may instead exacerbate other severe symptoms. If cold pathogenic factors are slight yet hot-natured medicines are overused, internally this leads to red eyes, sore throat, phlegm obstruction, and shortness of breath; externally, it results in ulcerated rashes, carbuncles, toxins, dry cracked skin, and a dry red appearance. If heat pathogenic factors are slight yet cold-natured medicines are overused, internally this causes vomiting, diarrhea, and abdominal distension; externally, it leads to involution, itching, and collapse of lesions. When the condition is slow-moving but urgent prescriptions are administered, urgency disrupts the meridians; when the condition is critical and "robbing" (strong purgative or resolving) medicines are indicated, using them too slowly fails to rescue life in time. One should use the fundamental prescription to treat the fundamental disease; once the disease is eliminated, further discussions on alternative strategies should follow. To prevent transformation syndromes by using medicines for transformed conditions, one must carefully anticipate future developments. Therefore, relying solely on tonification methods does not necessarily imply universal weakness; rigidly employing acrid-warm herbs does not imply that all cases are deficiency-cold. Combine when appropriate, discard when necessary; let the medicine adapt to the shifting disease, with the key lying in the practitioner's judgment. Thus, *Shengma* (Cimicifugae Rhizoma) should be advanced before eruption occurs, unless there is severe diarrhea, in which case it should not be administered; *Huangqi* (Astragali Radix) is used during the pus-formation stage, but only when Qi deficiency is present. If the body lacks high fever, do not add *Gegen* (Puerariae Lobatae Radix) or *Chaihu* (Bupleuri Radix); if the face is not excessively red, do not administer *Qinlian* (Scutellariae Baicalensis Radix et Coptidis Rhizoma), *Qiao* (Lonicerae Japonicae Flos), or *Jiejie* (Schizonepetae Spica). For obstruction and stagnation, only dredging and unblocking are permitted; administering tonics will cause chest fullness and reduced appetite. Internal heat is suitable for clearing and draining; excessive diaphoretic herbs lead to surface ulceration and sore sores. Heat obstruction causing irritability requires caution with *Dingxiang* (Caryophylli Flos) and *Guirou* (Cinnamomi Cortex), as they may affect the eyes; loose stools and weak stomach function mean that misusing *Qinlian* could be fatal. For food stagnation causing acid regurgitation, digestion-promoting and guiding-out methods are first indicated; for anorexia and dry retching, harmonizing the stomach is required. Scorched, hot diarrhea indicates that warming and tonifying are inappropriate; loose, clear, and thin diarrhea indicates that cooling medicines are altogether unsuitable. Tonifying Yin when the Stomach is weak may worsen diarrhea; benefiting Yang when the Sanjiao (Triple Burner) is obstructed may provoke mania or epilepsy. With wheezing, fullness, and clear urination/defecation, although there is irritability, tonification is permissible; with coarse breathing and abdominal distension resembling constipation, unblocking is appropriate. For cough with phlegm, avoid indiscriminate use of *Banxia* (Pinelliae Rhizoma); for vomiting caused by rising heat, introduce *Ganjiang* (Zingiberis Rhizoma) slowly. For Qi deficiency lacking vigor, *Renshen* (Ginseng Radix et Rhizoma) brings quick results; for Spleen-Stomach deficiency-cold, *Guizhi* (Cinnamomi Ramulus) and *Fuzi* (Aconiti Lateralis Radix Praeparata) achieve success. *Qinlian* clears heat toxins before they manifest; *Jingqiao* (Schizonepetae Spica et Lonicerae Japonicae Flos) clears blood heat from blood blisters. However, if the pathological trend is in the pustule-filling stage, such medicines are rejected. If within six to seven days the lesions do not rise, *Baoyuan Tang* (Preserve the Origin Decoction) is not prohibited; if after eight to nine days the generation is slow, why delay *Yigong San* (Extraordinary Merit Powder)? Tonification should not be applied too early; adding warming medicines must come later. Dispersing and releasing the exterior serves as the vanguard, while warming and tonifying serve as the rear guard.