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Xionghuang (Realgar) inherits the nature of Fire and Earth, generated by pure Yang Qi, thus possessing acrid and bitter flavors. Its property is greatly warm and toxic. It enters the Foot-Yangming Stomach Meridian and Foot-Jueyin Liver Meridian. It primarily eliminates demonic spirits and evil qi, as well as Zhong'e abdominal pain and Guizhu (a chronic consumptive disease caused by evil qi). This is because when the Yangming channel is deficient, evil qi easily invades; when Yin qi prevails, demonic entities easily attach themselves. Things that possess pure Yang Qi can dispel darkness, thereby eliminating all kinds of demonic evils. For symptoms such as alternating cold and heat, Shuluo (scrofula), malignant sores, Gan hemorrhoids, dead flesh, scabies parasites, and various ulcerations, these are all caused by damp-heat stagnating in the muscles, eroding and generating parasites. This drug's bitter and acrid properties can dry dampness and kill parasites, making it an essential medicine for treating sores. It treats nasal polyps due to Lung Qi stagnation; Piqi (abdominal masses) due to Large Intestine accumulation; eye pain due to Liver Meridian pathology; and severed tendons and bones due to discontinuity of Qi and Blood. Acridity disperses stagnation, warmth promotes the circulation of Qi and Blood; their combination kills parasites, thus enabling the extraction of severe wind accumulations from all joints. Huishe (venomous snakes) are Yin creatures, Lilu (Veratrum nigrum) is a Yin herb, while Xionghuang possesses pure Yang Qi, allowing it to effectively kill various insects, snake venoms, and detoxify Lilu. It exerts significant effects on the Jueyin Meridian. It can also transform blood into water, serving purposes of resolving stasis, killing parasites, and detoxification.

Xionghuang treats malignant sores, Jinchuang (traumatic wounds from metal weapons), alternating cold and heat, Shuluo, scabies ulcers, and nasal polyps. It kills demonic spirits, evil qi, hundred insects, Yangdu (toxic sores), Dingchuang (carbuncles), xuan (tinea), snake venom, conditions causing tendon rupture and bone fracture, accumulations and Piqi, Zhong'e abdominal pain, and Guizhu. It treats Xiao'er Gangan eye diseases caused by Liver Gan, calms fright with anti-demonic properties, searches Liver Qi, drains Liver Wind, resolves phlegm accumulations, treats Xiemal (malaria-like fevers), severe wind in bones and joints, Jiupi (wine-related disorders) and Jingxian (convulsions), Toufeng dizziness, and resolves abdominal blood stasis, killing Laoguan parasites. It detoxifies Lilu; pregnant women wearing it may give birth to males. However, mineral drugs are devoid of affection towards Qi and Blood; those suffering from Ganlao due to Yingwei deficiency should not take it. Wearing Cihuang (Pararealgar) instead transforms male births into female births. In medicinal use, it specifically treats all insect poison and malignant sores.

For Ganji leading to damaged eyes with white nebula obscuring vision, taking this formula turns red and gradually clears the opacity; truly a miraculous prescription. The formula uses Sangbaipi (Morus Alba Root Bark) 5-6 qian, dried on a tile and finely ground; one Xiongji Yinganpi (Rooster's Inner Membrane/Ji Neijin), dried in shade, toasted on a tile until yellow, and finely ground; mixed with Ming Xionghuang (Refined Realgar) about 1 qian. These three ingredients are blended evenly, applied onto Xiongji Ruan Gan (Rooster's Soft Liver), cooked in fermented rice wine within a copper vessel, then the medicine removed and the liver eaten. One per day yields miraculous effects. Grind into fine powder, insert into Pig Dan (Gallbladder), apply to the finger tip to treat Tianshe Dingdu (herpes zoster or similar toxin) occurring on the middle finger. For summer-toxin malaria and dysentery unresponsive to other methods: grind Xionghuang fine, sublimated nine times, steamed in bamboo tube seven times, re-ground, mixed with steamed dough pills sized like paulownia seeds. Take 7 pills with Licorice decoction, three times daily. The rhyme states: Summer toxin resides in Spleen, dampness connects to feet; without diarrhea there is dysentery, without dysentery there is malaria. Refining only Xionghuang and mixing with dough for treatment is a major error by physicians. This is a formula obtained in dreams by ancients, tested and effective. *Shenghui Fang*: Shanghan Fuhuo disease, worms eating the lower part, incessant pain and itching; burn half liang of Xionghuang in a bottle to fumigate the lower part. *Zhouhou Fang*: Wushizhu disease, characterized by unpredictable pain, confusion, heaviness, entangling viscera, rushing up to heart and hypochondrium, indicating harm by corpse ghosts. Mix Xionghuang and Da Suan (Garlic) each 1 liang, pound into pills size of a bullet. Take one pill with hot wine. *Xia Shi Qiji Fang*: Worms in muscles/flesh moving under skin like crabs, making sounds causing infant crying, transformation of muscle to worm. Mix Xionghuang and Leiwan (Wormwood fruit/Polyporus) each 1 liang, powder, sprinkle on pork, roast thoroughly, consume entirely for relief. *Jide Tang Fang*: Malignant sores in Guangdong. Use Xionghuang 1.5 qian, Xingren (Apricot Seed) 30 kernels peeled, Qingfen (Calomel) 1 qian. Grind to powder. Cleanse wound, mix with Xiong Zhu Dan (Boar Gallbladder juice) for application. Heals in 2-3 days, 100% effective, the world's best formula. From the residence of Marquis Wuding Hou; adding Longnao (Borneol) enhances efficacy.

Main Indications (Integration with Smallpox/Rash): Resolves phlegm, treats fright, detoxifies smallpox, kills insects, promotes tissue regeneration, corrects blackened sunken lesions; also used as an additive in other preparations.