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The differentiation of diseases into meridians and zang-fu organs is well known to everyone. Consequently, the world has fallen into rigid adherence and forced interpretations based on the theory of meridians and zang-fu organs, or even erroneous and far-fetched understandings, with some even mystifying these theories to deceive others. In fact, there are numerous methods for treating diseases; some require an investigation into meridians and zang-fu organs, while others do not. The qi and blood of the human body circulate without obstruction, and the properties of herbs—whether cold, hot, warm, or cool, toxic or non-toxic—are fixed and unchanging. Once entering the human body, their functions can reach anywhere. How could it be that a specific herb only enters a particular meridian? For instance, Ginseng Radix et Rhizoma (Renshen) tonifies everywhere. Arsenic (Pishuang) and poisoned fowl (Zhen) are toxic everywhere; they do not act exclusively in one location. Therefore, ancient physicians had ready-made universal formulas, such as Zijin Ding (Purple Gold锭) and Zhibao Dan (Precious Treasure Pill), which treat many diseases and yield miraculous effects. Those that promote the circulation of Qi have no stagnation they cannot resolve; those that detoxify have no poison they cannot eliminate; those that resolve Phlegm have no turbidity they cannot dissipate. Within these, there may be slight specific preferences. However, Zhang Jiegu and his contemporaries claimed that each herb uniquely enters a specific meridian; this is all forced interpretation and lacks evidentiary value. One might ask: Then, should medication not differentiate between meridians and zang-fu organs at all? I say: This is incorrect. Diseases manifest in specific locations in the body, and herbs possess specialized therapeutic efficacies. For example, Bupleuri Radix (Chaihu) treats alternating chills and fever and can cure Shaoyang disease; Cinnamon Twig (Guizhi) treats aversion to cold and fever and can cure Taiyang disease; Puerariae Radix (Gegen) treats intense limb heat and can cure Yangming disease. Their ability to resolve chills and fever, alleviate aversion to cold, and clear intense heat is their specialized function. Because they can treat diseases of certain meridians, later generations labeled them as herbs for those meridians. Who knows that their functions actually extend beyond just entering the Shaoyang, Taiyang, or Yangming meridians? Even in obvious cases like this, other instances are even less substantiated. Thus, it is acceptable to say that a certain herb can treat diseases of a certain meridian in a general sense, but unacceptable to say it exclusively treats that meridian. It is acceptable to state that for a disease of a certain meridian, a certain herb should be used; but it is unacceptable to claim that a herb never enters other meridians. Therefore, using herbs without understanding meridians leads to vagueness and inevitably fails to produce rapid effects. Rigidly adhering to meridians when using herbs leads to inflexibility and can cause harm. In summary, variations are endless; divine comprehension depends on the practitioner.