〔《活》〕病患身冷，脉沉细疾，烦躁而不饮水者，阴盛隔阳也，宜服霹雳散，须臾躁止得睡，汗出即瘥。
火焰散、丹砂丸并主之。（丹砂丸方见《活人书》。）
霹雳散 治阴盛隔阳，烦躁不饮水。
附子（一枚，炮熟取出，用冷灰挹，细研，入真腊茶二钱和匀。）
上为细末，分作二服，水二盏，煎至六分，临熟入蜜半匙，放温或冷服之，须臾躁止得睡，汗出即瘥。
〔海〕已寒丸 此丸不僭上，阳生于下，治阴症服四逆辈，胸中发躁而渴者，或数日大便秘，小便涩，亦服此丸。
上不躁，大小便自利。
肉桂 茯苓（各五钱） 良姜 乌头（炮。各七钱） 附子（炮） 干姜（炮） 芍药 茴香（炒。各一两）
上等分，为细末，糊为丸，如桐子大。温酒下，空心服五七十丸，八九十丸亦得，酒醋为糊俱可。
〔《本》〕破阴丹治阴中伏阳烦躁，六脉沉伏。（方论见阴毒。）
顷年乡人李信道得疾，六脉沉伏不见，深按至骨则若有力，头疼身温，烦躁，指末皆冷，胸中满，恶心。
更两医矣，皆不识，止用调气药。予诊之曰∶此阴中伏阳也，仲景法中无此证，世人患此者多。若用热药以助
之，则为阴所隔绝，不能导引真阳，反生客热；用冷药则所伏真火愈见消烁，非其治也。须用破散阴气，导达
真火之药，使火升水降，然后得汗而解矣。予授此药二百粒，作一服，冷盐汤下，不时烦躁狂热，手足躁扰，
其家大惊。予曰∶俗所谓换阳也。须臾稍定，略睡，身已中汗，自昏达旦方止，身凉而病除矣。
[From *Huoren Shu* (Book of Living Persons)] When a patient presents with cold limbs, a deep, fine, and rapid pulse, irritability without desire to drink, this is due to excess Yin repelling Yang. It is appropriate to administer Pili San (Thunderbolt Powder). After a short while, the restlessness ceases, sleep ensues, and recovery follows upon sweating.
Huoyan San (Flame Powder) and Dansha Wan (Cinnabar Pill) also treat this condition. (The formula for Dansha Wan is found in *Huoren Shu*.)
Pili San: Treats excess Yin repelling Yang, causing irritability and aversion to drinking.
Fuzi (Aconiti Lateralis Radix Praeparata, one piece, processed until cooked, removed, covered with cold ash to absorb moisture, finely ground), combined with Zhen Cha (Camelliae Sinensis Folium, two qian). Mix evenly.
Grind the above into a fine powder. Divide into two doses. Decoct with two cups of water until reduced to six-tenths. Just before completion, add half a spoonful of honey. Take warm or cold. After a short while, restlessness ceases, sleep ensues, and recovery follows upon sweating.
[Hai Zang] Yihan Wan: This pill does not cause hyperactivity of fire in the upper jiao; Yang Qi arises from the lower jiao. It treats Yin syndromes where, after administering Sini Tang-type formulas, the patient experiences chest irritability and thirst, or constipation and dysuria persisting for several days.
After administration, there is no irritability in the upper body, and bowel movements and urination become normal.
Rougui (Cinnamomi Cortex), Fuling (Poria), Liangjiang (Alpiniae Officinarum Rhizoma), Wutou (Aconiti Radix, processed), each seven qian; Fuzi (Aconiti Lateralis Radix Praeparata), Ganjiang (Zingiberis Rhizoma, processed), Shaoyao (Paeoniae Radix Alba), Huixiang (Foeniculi Fructus, stir-fried), each one liang.
Divide equally, grind into a fine powder, and bind with paste to form pills the size of paulownia seeds. Take with warm wine on an empty stomach, 50-70 pills, or up to 80-90 pills are acceptable. Paste made with wine or vinegar is also suitable.
[From *Bencao Yan Yi* (Supplement to Materia Medica)] Po Yin Dan: Treats irritability caused by latent Yang within Yin, with six pulses being deep and hidden. (The discussion of the formula is found under "Yin Du" [Yin Toxin].)
In recent years, my fellow townsman Li Xindao fell ill. His six pulses were deep and hidden, but felt forceful when pressed deeply to the bone. He had headache, warm body, irritability, cold fingertips, chest fullness, and nausea.
Two other physicians treated him but failed to recognize the condition, prescribing only qi-regulating herbs. I diagnosed it as "latent Yang within Yin." This syndrome is not recorded in Zhang Zhongjing's methods, yet many people suffer from it today. If hot herbs are used to assist it, they will be repelled by the Yin, failing to guide the True Yang, and instead generating exogenous heat. If cold herbs are used, the hidden True Fire will be further depleted. This is not the correct treatment. One must use herbs that break up and dissipate Yin Qi and guide and unblock the True Fire, allowing Fire to ascend and Water to descend, so that resolution occurs through sweating. I prescribed two hundred pills of this medicine as a single dose, taken with cold salted water. The patient experienced intermittent irritability, feverish sensation, and restless tossing of hands and feet, alarming his family. I said, "This is what laypeople call 'changing Yang'." After a short while, he stabilized slightly, slept briefly, and then sweated profusely. This continued from dusk until dawn, after which his body cooled and the illness was cured.