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Congenital absence of skin in newborns has two main etiologies: one is transmission from parents suffering from syphilis; the other is prematurity, where the fetus is born before full term. The condition presents with missing skin, erythema and ulceration, and unbearable pain.

For cases caused by residual venereal toxins (syphilis), administer HuANJI Xiaodu San internally and apply Qingliang Ehuang Fen externally. Once the toxin is resolved and the body structure is complete, the skin will naturally grow firm and intact.

[Annotation]
Infants born without skin present with two types of syndromes:
One type results from parents having had Yangmei Jiedu (chancre of syphilis) previously, which infects the fetal sac. Consequently, upon birth, the infant may exhibit erythema and ulceration on either the upper or lower body, or even a purplish-black discoloration.
The other type results from premature delivery due to insufficient gestational months, causing the entire body's skin to be macerated, red, tender, and shiny.

For cases attributed to malignant conditions and residual toxins, administer Huanji Xiaodu San internally, and apply Qingliang Gao or Ehuang San externally.
For cases of deficient fetal origin (congenital weakness), administer Danggui Yin internally, and apply rice flour externally.
"Resolution of toxin and completion of form" refers to the elimination of toxic qi, after which the skin will gradually regenerate, becoming complete and robust.

[Huanji Xiaodu San Formula]
Ingredients: Dang Gui (Angelicae Sinensis Radix), Sheng Di Huang (Rehmanniae Radix Recens), Chi Shao Yao (Paeoniae Radix Rubra), Chuan Xiong (Ligustici Chuanxiong Rhizoma), Zao Ci (Gleditsiae Spina), Tu Fu Ling (Smilacis Glabrae Rhizoma), Jin Yin Hua (Lonicerae Japonicae Flos), Lian Qiao (Forsythiae Fructus, heart removed), Gan Cao (Glycyrrhizae Radix et Rhizoma), Sheng Bai Zhi (Angelicae Dahuricae Radix), Ku Shen (Sophorae Flavescentis Radix), Bai Xian Pi (Dictamni Cortex), Fang Feng (Saposhnikoviae Radix).
Administration: Decoct with Deng Xin Cao (Junci Medullia) water.

[Formula Song]
Wu pi huan ji xiao du zhi, Si wu zao ci tu fu ling,
Yin hua lian qiao cao bai zhi, Ku shen bai xian gong fang feng.

[Danggui Yin Formula]
Ingredients: Zhi He Shou Wu (Polygoni Multiflori Preparata Caulis), Bai Xian Pi (Dictamni Cortex), Bai Ji Li (Tribuli Fructus), Gan Cao (Glycyrrhizae Radix et Rhizoma), Dang Gui (Angelicae Sinensis Radix), Sheng Di Huang (Rehmanniae Radix Recens), Bai Shao Yao (Paeoniae Radix Alba), Ren Shen (Ginseng Radix), Huang Qi (Astragali Radix), Chuan Xiong (Ligustici Chuanxiong Rhizoma).
Administration: Decoct with water.

[Formula Song]
Dang gui yin zhi er wu pi, Mian bai zhi leng fu zui yi,
Shou wu xian pi bai ji li, Gan cao si wu gong shen qi.

[Qingliang Gao Preparation]
Take four liang of Shi Hui (Calcium Carbonatum) that has been soaked in Zhu Sha Shui (Cinnabar water) until it forms lumps. Soak it in water to a depth slightly exceeding half an inch. Leave it exposed overnight. When cloud-like flakes float on the surface, gently collect them, retaining a small amount of clear water. Add an equivalent amount of Xiao Mo Xiang You (Sesame Oil) based on the quantity collected. Stir clockwise until a paste forms. Apply with a chicken feather for spontaneous healing.

[Ehuang San Preparation]
Ingredients: Sheng Huang Bo (Phellodendri Cortex raw), Shi Gao (Gypsum Fibrosum) in equal parts. Calcine and grind into a fine powder.
Administration: For moist lesions, apply dry powder; for dry lesions, mix with Pig Gallbladder Juice (Zhu Dan) and apply.

[Rice Flour Method]
Grind white grains of dry-rice (Han Dao) into powder. Apply frequently to the affected area. The skin will gradually regenerate with miraculous efficacy.

Section on Newborns