一、痘三日之后，当逐渐起胀，若红绽，顶肥满光泽者，不必用药，皆吉证也。
一、痘当起胀之时，根窠全然不起，头面皮肉红肿，瓠瓜之状者，决死。
一、痘当起胀之时，遍身痘疔皆黑，其中有眼如针孔，紫黑者，决死。
一、痘当起胀之时，遍身痘陷伏不起者，腹中膨胀，不能饮食，气促神昏者，决死；如六日内，痘
尚红紫满顶者，即死。
一、痘当起胀之时，腰腹或痛，遍身尚是紫点如蚊虫咬，全不发换者，决死。
一、痘当起胀之时，黑陷闷乱，神气昏懵者，决死。
方
内托散 治气血虚损，或风邪秽毒冲触，使疮毒内陷，伏而不
出，或出而不匀快，此药活血匀气，调胃补虚，内托疮毒，使之尽出，易收易靥。
人参（二钱） 黄 （二钱） 当归（二钱） 川芎（□□） 防风（一钱） 桔梗（一钱）
白芷（一钱） 浓朴（姜汁炒，一钱） 甘草（生，一钱） 木香（三分） 肉桂（三分）
上方于红紫黑陷，属热毒者，去桂，加紫草、红花、黄芩；若淡白灰黑陷伏，属虚寒者，加丁香救里，
官桂救表；当贯脓而不贯脓者，倍参、 、当归，煎熟，入人乳，好酒温服。泄泻，加丁香、干姜、肉豆蔻。
木香散 性温平，能和表里，通行津液，清上实下，扶阴助阳之药，专治小儿痘疮，脓胀渴泻，其效如神。
木香 丁香 官桂 半夏（姜制） 陈皮 前胡 大腹皮 赤茯苓 人参 甘草（炙） 诃子
肉（煨，去核，各三分）
上锉，每三钱，生姜煎服，量儿大小加减。服药后，忌蜜水。
异功散 治小儿痘疮欲靥之际，头温足指冷，或腹胀泄泻，口
渴气促，或身不热，寒战，闷乱不宁，卧则哽气，烦渴切牙，急服此。切不可与蜜水、红柿、西瓜、梨果食之。
人参 白术 陈皮 白茯苓 丁香 当归 木香 浓朴（姜制） 官桂 大腹子
（泡，去皮、脐） 半夏（姜炒） 肉豆蔻（面裹煨，槌去油，各三分）
上锉，每三钱，生姜三片，枣一枚，水煎热服。
固真汤 治小儿痘疮虚泻，神效。
黄 人参 甘草（炙） 陈皮 白术 木香 白芍（炒） 白茯苓
诃子（煨，去核） 肉豆蔻（面裹煨，纸包，槌去油，各等分）
上锉，粳米三十粒，水煎，温服。
肉豆蔻丸 专治痘疮，里虚泄泻。
木香（二钱） 砂仁（二钱） 诃子肉（五钱） 肉豆蔻（煨，五钱） 白龙骨（五钱）
枯白矾（七钱半） 赤石脂（七钱半）
上为末，糕糊为丸，如黍米大。周岁儿，五十丸；三岁，百丸。温米汤下。泻甚者，异功散吞下，泻
止住服，不止多服。
无价散 治痘黑陷而焦。
人牙 猫牙 犬牙 猪牙
上等分，各将炭火烧留烟，瓦碗盖蔽，存性，为末。每五六岁，
服三四分，好热酒调下；痒塌寒战，泄泻者，煎异功散调下。若无猫牙，用人牙一味亦妙，但不如四牙全方。
人牙散 治痘疮初起，光壮，忽然黑陷，心中烦躁，气急喘满，狂言妄语，如见鬼神，急宜治之，不
然毒瓦斯入脏，必死。
人牙烧存性，为末，每一个作一服，酒调下。
独圣散 治痘六七日陷而不发，及不贯脓，有泻不宜服，陷入黑色，气欲绝者，神效。
穿山甲（泡，洗，冷净，用炭火拌炒，成珠焦黄为度）
上为末，每服五分，或六七分，木香汤或紫草汤，入酒更妙，糯米清汤亦可。
秘传复生散 治痘疮黑陷不起发。
珍珠（一钱） 琥珀（一钱） 雄黄（一钱） 穿山甲（一钱） 朱砂（一钱） 两头尖
（一钱） 香附子（一钱） 真蟾酥（五分）
上先将蟾酥切片，以人乳汁浸少时，入众药搓匀。一岁儿服八厘，三二岁儿服一分二厘，用熟蜜水调下。
兔血丸 治痘疮不起发。
十二月收下兔血 白雄乌鸡血
好朱砂 广木香 小儿退下乳牙（ 黄色） 雄黄
上六味，各一钱，共为细末。每服五分，黄酒送下，汗出即起发。
归茸酒 凡痘疮已成，出齐而难胀，或已胀齐而难靥者，由内虚故耳，盖痘既出，灰白色，及顶平不
起，或陷伏者，气血大虚也。嫩鹿茸酥炙，当归身酒洗，每锉五钱，好酒煎，温服。
无比散 治痘焦枯黑陷，极热毒炽恶候。
牛黄（五钱） 片脑（五钱） 朱砂（三钱） 腻粉（五钱） 麝香（一钱）
上为末，每五六七岁者，服五分，新汲井泉水调下，或加小猪尾血三五滴调下，尤妙。
人中黄散 治痘六七日不肥满，及陷入，及不贯脓，服此神效，泻亦无妨，解毒排脓。
人中黄，即粪缸内浓垢，采来，或成块者，炭火中 过通红，
取出火毒，研细为末。每服一茶匙，酒调服，糯米清汤亦可。
秘方 治痘不起发。
雄黄（三钱） 天灵盖（一两，火 ，小儿者佳） 寒水石（八钱，火 ）
上为末，糯米浓饮为丸，如梧桐子大，朱砂为衣。每服一丸，用热酒化下，出汗即长效。
万金散 治瘢疮不出，黑陷至死者。
人猫猪犬腊辰烧，少许微将蜜水调，百者救生无一死，黄金万锭也难消。
上将四物粪，于腊日早晨，日未初时，贮于银锅内，炭火 ，令烟尽，白色为度。但是疮发不快，
倒靥黑陷者，及一切恶疮，每用一字，蜜水调服，其效如神。
蜜皂丸
蜜皂专医粪不通，发狂谵语小便红，炼蜜微和牙皂末，捻梃令安谷道中。
上用蜜二三两，熬如饴，加皂角末二钱，搅匀，捻作梃子三四条，将一条纳谷道中，如不通，再易一条，
必通矣。自出痘至收靥时，理不宜下者，用此导之。若既靥之后，有前证者，又当下也。
四圣丹 治痘疮，中有长大紫黑者，为疔毒，把住痘不起发，急用银簪挑破， 入此丹。
珍珠（三五粒，铁器土爆微黄色） 豌豆（四十九粒，烧灰存性） 头发（烧灰存性，不拘多少）
上为细末，用擦面油胭脂调成膏子，将儿在温燠处安存，忌风寒秽气。先用簪尖平拨开疔，将药
入疔内，即变红色，全疮皆起，但挑破出黑血，或用棉裹指掏去黑血，即愈，盖疔破而毒瓦斯得散也。
国老散 治痘疮、瘢疮、疔肿、痈疽、诸般恶毒，及中砒毒，用毒伤寒发狂言，并治。
五月初四日，预选大甘草不拘多少，研细末，却用大竹一段，
两头留节，钻一头作小孔，装入甘草末于内，其孔用木塞固，勿令泄气，用绳缚竹，候至端午日，置粪缸中
以砖坠竹至底，四十九日，取出长流水洗净候干，取药晒燥，再研细，贮瓷器内。如遇小儿
出痘见苗，每服一钱，淡砂糖汤调服，及诸般恶毒，并用砂糖汤调服，大能解毒，神效。
祛毒散 治痘疮作毒，发痈疽。
猪苓 泽泻 白术 赤茯苓 官桂 防风 羌活 牛蒡子（炒） 黄连 柴胡 甘草（各等分）
上锉，生姜、灯草、薄荷，水煎服。
1. After three days of the eruption, the pustules should gradually rise and swell. If the pustules are red and blooming, with full, glossy tops, no medication is needed; these are auspicious signs.
2. When the pustules should be rising and swelling, if the bases do not rise at all, and the skin and flesh of the head and face are red and swollen, resembling a calabash (Hu Gua), death is certain.
3. When the pustules should be rising and swelling, if all pustules on the body turn black, with eyelets like needle holes and purple-black color, death is certain.
4. When the pustules should be rising and swelling, if the pustules on the whole body are depressed and fail to rise, accompanied by abdominal distension, inability to eat, shortness of breath, and coma, death is certain; if within six days the pustules remain red-purple and full-topped, death will occur immediately.
5. When the pustules should be rising and swelling, if there is pain in the waist or abdomen, and the body still shows purple spots like mosquito bites, completely failing to transform and swell, death is certain.
6. When the pustules should be rising and swelling, if black depression occurs with restlessness and confusion, and the spirit is dull and muddled, death is certain.
Formula:
Neituo San (Internal Support Powder): Treats deficiency of Qi and Blood, or invasion by Wind pathogen and filth toxin that causes the sore toxin to sink internally, remaining latent without emerging, or emerging unevenly and slowly. This formula invigorates blood, regulates Qi, harmonizes the Stomach, tonifies deficiency, supports the sore toxin from within, causing it to emerge completely, facilitating easy healing and scabbing.
Ren Shen (Ginseng Radix et Rhizoma) (2 qian) Huang Qi (Astragali Radix) (2 qian) Dang Gui (Angelicae Sinensis Radix) (2 qian) Chuan Xiong (Ligustici Chuanxiong Rhizoma) (?) Fang Feng (Saposhnikoviae Radix) (1 qian) Jie Geng (Platycodonis Radix) (1 qian)
Bai Zhi (Angelicae Dahuricae Radix) (1 qian) Hou Po (Magnoliae Officinalis Cortex) (stir-fried with ginger juice, 1 qian) Gan Cao (Licorice Radix et Rhizoma, raw, 1 qian) Mu Xiang (Aucklandiae Radix) (3 fen) Rou Gui (Cinnamomi Cortex) (3 fen)
For cases where the pustules are red, purple, or black and depressed, indicating Heat Toxin, remove Rou Gui, and add Zi Cao (Arnebiae Radix seu Lithospermi Radix), Hong Hua (Carthami Flos), and Huang Qin (Scutellariae Radix). For cases where the pustules are pale white, gray, or black and depressed, indicating Deficiency Cold, add Ding Xiang (Caryophylli Flos) to rescue the Interior, and Guan Gui (Cinnamomi Cortex) to rescue the Exterior. When pus formation is delayed, double the dosage of Ren Shen, Huang Qi, and Dang Gui, decoct until cooked, add human milk, and take warm with good wine. For diarrhea, add Ding Xiang, Gan Jiang (Zingiberis Rhizoma), and Rou Dou Kou (Myristicae Semen).
Muxiang San (Costus Root Powder): The nature is warm and neutral; it harmonizes the Exterior and Interior, promotes the circulation of Body Fluids, clears the Upper Jiao and solidifies the Lower Jiao, supporting Yin and assisting Yang. It is specifically used for pediatric smallpox/chickenpox with symptoms of pus swelling, thirst, and diarrhea, with miraculous efficacy.
Mu Xiang (Aucklandiae Radix) Ding Xiang (Caryophylli Flos) Guan Gui (Cinnamomi Cortex) Ban Xia (Pinelliae Rhizoma) (prepared with ginger) Chen Pi (Citri Reticulatae Pericarpium) Qian Hu (Peucedani Radix) Da Fu Pi (Arecae Pericarpium) Chi Fu Ling (Poria Cocos with Red Mycelium) Ren Shen (Ginseng Radix et Rhizoma) Gan Cao (Licorice Radix et Rhizoma, honey-fried) He Zi Rou (Terminalia Chebulae Fructus pulp) (roasted, pitted, each 3 fen)
Chop the herbs, take 3 qian per dose, decoct with fresh ginger, and adjust dosage according to the child's age. After taking the medicine, avoid honey water.
Yigong San (Extraordinary Efficacy Powder): Used when pediatric smallpox/chickenpox is about to heal (scab over). Symptoms include warmth in the head and cold toes, abdominal distension and diarrhea, thirst and shortness of breath, or absence of fever but with chills, restlessness and agitation, sighing while lying down, irritability, intense thirst, and teeth grinding. Take this urgently. Do not give honey water, persimmons, watermelon, or pear fruits.
Ren Shen (Ginseng Radix et Rhizoma) Bai Zhu (Atractylodis Macrocephalae Rhizoma) Chen Pi (Citri Reticulatae Pericarpium) Bai Fu Ling (Poria Cocos) Ding Xiang (Caryophylli Flos) Dang Gui (Angelicae Sinensis Radix) Mu Xiang (Aucklandiae Radix) Hou Po (Magnoliae Officinalis Cortex) (prepared with ginger) Guan Gui (Cinnamomi Cortex) Da Fu Zi (Areca Seed)
(soaked, peel and navel removed) Ban Xia (Pinelliae Rhizoma) (stir-fried with ginger) Rou Dou Kou (Myristicae Semen) (wrapped in flour, roasted, pounded to remove oil, each 3 fen)
Chop the herbs, take 3 qian per dose, with three slices of fresh ginger and one jujube, decoct in water, and take hot.
Guzhen Tang (Solidify True Decoction): Treats pediatric smallpox/chickenpox with deficiency-type diarrhea, with miraculous effects.
Huang Qi (Astragali Radix) Ren Shen (Ginseng Radix et Rhizoma) Gan Cao (Licorice Radix et Rhizoma, honey-fried) Chen Pi (Citri Reticulatae Pericarpium) Bai Zhu (Atractylodis Macrocephalae Rhizoma) Mu Xiang (Aucklandiae Radix) Bai Shao (Paeoniae Radix Alba) (stir-fried) Bai Fu Ling (Poria Cocos)
He Zi (Terminalia Chebulae Fructus) (roasted, pitted) Rou Dou Kou (Myristicae Semen) (wrapped in flour, roasted, wrapped in paper, pounded to remove oil, equal parts)
Chop the herbs, add thirty grains of Oryza Sativa Germ (Jing Mi), decoct in water, and take warm.
Roudoukou Wan (Nutmeg Pill): Specifically treats smallpox/chickenpox with interior deficiency and diarrhea.
Mu Xiang (Aucklandiae Radix) (2 qian) Sha Ren (Amomi Fructus Rotundus) (2 qian) He Zi Rou (Terminalia Chebulae Fructus pulp) (5 qian) Rou Dou Kou (Myristicae Semen) (roasted, 5 qian) Bai Long Gu (Fossilia Ossis Mastodi) (5 qian) Ku Bai Fan (Alumen Exsiccatum) (7.5 qian) Chi Shi Zhi (Halloysit Rubra) (7.5 qian)
Grind into fine powder, make pills using rice paste, size of Setaria Italica seeds. For one-year-old infants, 50 pills; for three-year-olds, 100 pills. Take with warm rice soup. For severe diarrhea, swallow with Yigong San; stop taking when diarrhea ceases, continue if it persists.
Wujia San (Priceless Powder): Treats smallpox/chickenpox with black depression and scorching dryness.
Ren Ya (Human Tooth) Mao Ya (Cat Tooth) Quan Ya (Dog Tooth) Zhu Ya (Pig Tooth)
Take equal parts, burn each with charcoal until smoke remains, cover with a clay bowl to preserve medicinal properties, grind into powder. For children aged five or six, take 3-4 fen, mixed with hot wine. For itching, collapse, chills, and diarrhea, mix with decocted Yigong San. If cat tooth is unavailable, using only human tooth is also effective, though not as good as the four-tooth formula.
Renya San (Human Tooth Powder): Treats early-stage smallpox/chickenpox that was bright and vigorous but suddenly became black and depressed, with mental restlessness, rapid breathing, chest fullness, delirium, hallucinations of ghosts and gods. Urgent treatment is required; otherwise, toxin enters the Zang organs, leading to death.
Burn human tooth until carbonized (preserve nature), grind into powder. One tooth constitutes one dose, taken with wine.
Dusheng San (Supreme Holy Powder): Treats smallpox/chickenpox depressed after six or seven days without erupting or forming pus. Contraindicated in diarrhea. For black depression with impending respiratory failure, it is miraculous.
Chuan Shan Jia (Manis Squama) (soaked, washed, cooled clean, stir-fried with charcoal until bead-like and scorched yellow)
Grind into powder. Take 5 fen per dose, or 6-7 fen, with Muxiang Tang or Zicao Tang, adding wine is better. Rice water is also acceptable.
Michuan Fusheng San (Secretly Transmitted Revival Powder): Treats smallpox/chickenpox with black depression and failure to erupt.
Zhen Zhu (Margarita) (1 qian) Hu Po (Electrum) (1 qian) Xiong Huang (Realgar) (1 qian) Chuan Shan Jia (Manis Squama) (1 qian) Zhu Sha (Cinnabaris) (1 qian) Liang Tou Jian (Bupleuri Radix et Scutellariae Radix mixture or specific herb, context implies Bupleuri/Scutellaria root tips) (1 qian) Xiang Fu Zi (Cyperi Rhizoma) (1 qian) Zhen Chan Su (Bufonis Venenum) (5 fen)
First slice the Chan Su, soak in human milk for a short time, then mix with other herbs evenly. For one-year-old infants, take 8 li; for two-to-three-year-olds, take 1.2 fen. Take with warm honey water.
Tuxue Wan (Rabbit Blood Pill): Treats smallpox/chickenpox failure to erupt.
Rabbit blood collected in the twelfth lunar month White male silkie chicken blood
High-quality Zhu Sha (Cinnabaris) Guang Mu Xiang (Aucklandiae Radix) Decayed deciduous teeth of children (yellowish) Xiong Huang (Realgar)
The above six ingredients, each 1 qian, grind into fine powder. Take 5 fen per dose, delivered with yellow wine. Sweating indicates eruption.
Guiron Jiu (Deer Antler and Angelica Wine): For smallpox/chickenpox that has formed and erupted fully but fails to swell, or has swelled fully but fails to scab, due to internal deficiency. Generally, if the eruption is ash-white, flat-topped, depressed, or sunken, it indicates severe Qi and Blood deficiency. Use tender Lu Rong (Cervi Cornu Pantotrichum) prepared with su (animal fat), and Dang Gui Shen (Angelicae Sinensis Radix radix part) washed with wine. Chop 5 qian, decoct in good wine, and take warm.
Wubi San (Peerless Powder): Treats smallpox/chickenpox with scorching dryness, black depression, and extreme Heat Toxin malignancy.
Niu Huang (Bovaris Calculus) (5 qian) Pian Nao (Borneolum Syntheticum) (5 qian) Zhu Sha (Cinnabaris) (3 qian) Ni Fen (Calomelas) (5 qian) She Xiang (Moschus) (1 qian)
Grind into powder. For children aged five to seven, take 5 fen, mixed with fresh well water. Adding 3-5 drops of piglet tail blood is especially effective.
Renzhonghuang San (Human Middle Yellow Powder): Treats smallpox/chickenpox that does not plump up after six or seven days, depression, and failure to form pus. Miraculous effect even with diarrhea. Resolves toxicity and expels pus.
Ren Zhonghuang (Human Middle Yellow), which is thick sludge from latrine pits, collected in clumps, calcined in charcoal fire until red-hot,
removed to eliminate fire toxicity, ground into fine powder. Take one tea spoon per dose, mixed with wine. Rice water is also acceptable.
Secret Formula: Treats smallpox/chickenpox failure to erupt.
Xiong Huang (Realgar) (3 qian) Tian Ling Gai (Calvaria Humana) (1 liang, calcined, pediatric source preferred) Han Shui Shi (Metasideritum) (8 qian, calcined)
Grind into powder, make pills with thick rice drink, size of Strychnos Nux-vomica seeds, coated with Zhu Sha. Take one pill per dose, dissolved in hot wine. Sweating ensures long-term efficacy.
Wanjina San (Ten Thousand Gold Powder): Treats scar-like eruptions that do not appear, black depression leading to death.
Burn feces of humans, cats, pigs, and dogs during the twelfth lunar month. Mix slightly with honey water. A hundred cases saved, none die; ten thousand ingots of gold cannot match this value.
Take the feces of the four animals, store in a silver pot on the morning of the last day of the year before sunrise, calcine over charcoal fire until smoke ceases and turns white. For any slow eruption, inverted scabbing, black depression, or all kinds of malignant sores, take one "zi" measure (approx. 0.5-1g), mixed with honey water. Miraculous effect.
Mi Zao Wan (Honey and Soap Pill)
Mi Zao (Honey and Soap Nut) specifically treats constipation, mania, delirium, and red urine. Refine honey, mix with crushed soap nut powder, roll into sticks for anal insertion.
Use 2-3 liang of honey, boil until like malt syrup, add 2 qian of Zao Jiao (Gleditsiae Sinensis Fructus) powder, mix evenly, roll into 3-4 sticks. Insert one stick into the anus. If blocked, replace with another. It will definitely unblock. From eruption to scabbing, purgatives are generally contraindicated; use this to guide evacuation. If symptoms persist after scabbing, purgation is indicated.
Sisheng Dan (Four Sages Pill): Treats smallpox/chickenpox with large, purple-black nodules, identified as Ding Du (Ding Toxin), blocking eruption. Urgently puncture with a silver hairpin,
insert this pill.
Zhen Zhu (Margarita) (3-5 grains, earth-baked in iron vessel until light yellow) Wan Dou (Viciae Sativae Semen) (49 grains, burned to ash preserving nature) Tou Fa (Capillus Humanus) (burned to ash preserving nature, any amount)
Grind into fine powder, mix with facial cream rouge to form a paste. Keep the child in a warm place, avoiding wind, cold, and filth. First, use the tip of the hairpin to flatten the Ding, apply the medicine inside the Ding. It will turn red, and the entire sore will rise. Puncture to drain black blood, or use cotton-wrapped finger to remove black blood. Healing occurs because the Ding breaks and toxin dissipates.
Guolao San (Old Man Powder): Treats smallpox/chickenpox, scar eruptions, Ding swelling, carbuncles, sores, various toxins, arsenic poisoning, and toxic typhoid with delirium.
On the fourth day of the fifth lunar month, select large Gan Cao (Licorice Radix et Rhizoma) in any quantity, grind into fine powder. Take a section of large bamboo,
keep nodes at both ends, drill a small hole at one end, fill with Gan Cao powder, seal the hole with wood plug to prevent gas leakage, tie bamboo with rope. Wait until Dragon Boat Festival (fifth day of fifth lunar month), place in latrine pit, weigh down bamboo to bottom with brick. After forty-nine days, retrieve, wash with flowing water, dry, grind finely again, store in porcelain. When pediatric smallpox/chickenpox appears, take 1 qian per dose, mixed with light sugar water. For various toxins, also use sugar water. Greatly resolves toxicity, miraculous effect.
Qudu San (Remove Toxicity Powder): Treats smallpox/chickenpox generating toxicity, developing carbuncles and sores.
Zhu Ling (Polyporus) Ze Xie (Alismatis Rhizoma) Bai Zhu (Atractylodis Macrocephalae Rhizoma) Chi Fu Ling (Poria Cocos with Red Mycelium) Guan Gui (Cinnamomi Cortex) Fang Feng (Saposhnikoviae Radix) Qiang Huo (Notopterygii Rhizoma et Radix) Niu Bang Zi (Arctii Fructus) (stir-fried) Huang Lian (Coptidis Rhizoma) Chai Hu (Bupleuri Radix) Gan Cao (Licorice Radix et Rhizoma) (equal parts)
Chop the herbs, decoct with fresh ginger, Deng Cao (Junci Medulla), and Bo He (Menthae Haplocalycis Herba) in water.