夫虚劳膝冷者。此由肾气弱。骨髓虚。为风冷所搏故也。肾居下焦。主于脚腰。其气荣
润骨
治虚劳。膝冷阴痿。四肢羸弱。宜服川椒丸方。
川椒（一两去目及闭口者微炒去汗） 菟丝子（二两酒浸三日曝干别捣为末） 桂心（三
分）
牛
宿刮去
皱
心） 防
风（
上件药。捣罗为末。炼蜜和捣三二百杵。丸如梧桐子大。每服。食前以温酒下三十丸。
治虚劳膝冷疼痛。下元伤惫。宜服补益干漆丸方。
干漆（一两捣碎炒令烟出） 续断（一两） 熟干地黄（一两） 牛膝（一两半去苗） 桂
心
（一两）
皮炙微黄
锉） 狗
去皱皮
炙干） 上件药。捣罗为末。炼蜜和捣三五百杵。丸如梧桐子大。每服。空心以暖酒下三
十丸。晚食
治虚劳乏弱。膝冷无力。宜服石斛丸方。
石斛（一两去根节） 黄 （三分锉） 桂心（三分） 白茯苓（一两） 山茱萸（一
两） 薯蓣
（一
戟（一
两）
上件药。捣罗为末。炼蜜和捣三五百杵。丸如梧桐子大。每服。空心以温酒下三十丸。
晚食
治虚劳伤惫。膝冷无力。小便利。不思食。宜服山茱萸丸方。
山茱萸（一两） 薯蓣（一两） 牛膝（一两半去苗） 天雄（一两炮裂去皮脐） 菟
丝子（二
两酒
锉）
覆盆
牡蛎粉
（一
上件药。捣罗为末。炼蜜和捣五七百杵。丸如梧桐子大。每服。食前以暖酒下三十丸。
治虚劳膝冷。补益气力。宜服鹿茸丸方。
鹿茸（三两去毛涂酥炙微黄） 桂心（一两） 石斛（一两去根锉） 蛇床子（一两） 补
骨脂
（一
分去
心）
黄锉）
熟干
上件药。捣罗为末。炼蜜和捣五七百杵。丸如梧桐子大。每于食前。以温酒下三十丸。
治虚劳膝冷。宜服补益黄 浸酒方。
黄 （一两锉） 萆 （一两半锉） 防风（一两半去芦头） 牛膝（二两去苗） 桂
心（一两）
石
附
子
上件药。细锉以绢袋盛。用酒二斗。于瓷瓶中浸。密封瓶头。候三日后。每于食前暖一
小盏
治虚劳损。肾腰疼。膝冷少力。补益驻颜。宜服菟丝子丸方。
菟丝子（三两酒浸三日曝干别捣为末） 车前子（二两） 白术（二两） 桂心（二两）
杜仲
（二
上件药。捣罗为末。炼蜜和捣五七百杵。丸如梧桐子大。每于食前。以温酒下三十丸。
治虚劳膝冷。附子丸方。
附子（半斤每日早以新汲水浸日一度换水浸经七日去黑皮薄切曝干为末） 石斛（四两
去
根锉）
上件药。捣罗为末。炼蜜和捣千余杵。丸如梧桐子大。每于食前。以温酒下三十丸。
治虚劳衰弱。绝阳阴痿。膝冷。宜服钟乳丸方。
钟乳粉（三两） 蛇床子（三分） 石斛（一两去根锉） 菟丝子（三两酒浸三日曝干
别捣为
末）
上件药。捣罗为末。炼蜜和捣三五百杵。丸如梧桐子大。每服。食前以温酒下三十丸。
For those suffering from cold knees due to deficiency exhaustion (Xu Lao), this condition arises from weak Kidney Qi and deficient bone marrow, compounded by invasion of wind-cold pathogenic factors. The Kidneys reside in the Lower Jiao (Lower Burner) and govern the legs and waist. Their Qi nourishes the bones. To treat deficiency exhaustion manifesting as cold knees, impotence, and emaciated weakness in the four limbs, it is appropriate to administer Chuanjiao Wan (Sichuan Pepper Pill).
Chuanjiao (Fructus Zanthoxyli, 1 liang; remove eyes and closed-mouth specimens, slightly stir-fry to remove moisture) Tusizi (Semen Cuscutae, 2 liang; soak in wine for three days, sun-dry, and separately pound into powder) Guixin (Cortex Cinnamomi, 3 fen) Niuxi (Radix Achyranthis Bidentatae, 1.5 liang; scrape off wrinkled skin) Fangfeng (Radix Saposhnikoviae, 1 liang)
The above herbs are pounded, sifted into powder, mixed with refined honey, and pounded 300–200 times until uniform. Form pills the size of paulownia seeds. Take 30 pills each time, administered before meals with warm wine.
To treat deficiency exhaustion causing cold and painful knees, along with depletion of the Lower Yuan (Root of Vitality), it is appropriate to administer Buyi Ganqi Wan (Dry Lacquer Tonic Pill).
Ganqi (Lacus Rhei, 1 liang; crush and stir-fry until smoke emerges) Xuduan (Radix Dipsaci, 1 liang) Shudihuang (Radix Rehmanniae Preparata, 1 liang) Niuxi (Radix Achyranthis Bidentatae, 1.5 liang; remove seed heads) Guixin (Cortex Cinnamomi, 1 liang) Duzhong (Cortex Eucommiae, 1 liang; scrape off rough bark, stir-fry until slightly yellow, and slice) Gouji (Rhizoma et Radix Cibotii, 1 liang; remove hair, stir-fry until dry)
The above herbs are pounded, sifted into powder, mixed with refined honey, and pounded 300–500 times until uniform. Form pills the size of paulownia seeds. Take 30 pills each time on an empty stomach with warm wine, and again after the evening meal.
To treat deficiency exhaustion characterized by fatigue and weakness, cold knees, and lack of strength, it is appropriate to administer Shihu Wan (Dendrobium Pill).
Shihu (Herba Dendrobii, 1 liang; remove root nodes) Huangqi (Radix Astragali, 3 fen; slice) Guixin (Cortex Cinnamomi, 3 fen) Baifuling (Poria, 1 liang) Shanzhuyu (Fructus Corni, 1 liang) Shuyu (Rhizoma Dioscoreae, 1 liang) Ji (Radix Sparganii, 1 liang)
The above herbs are pounded, sifted into powder, mixed with refined honey, and pounded 300–500 times until uniform. Form pills the size of paulownia seeds. Take 30 pills each time on an empty stomach with warm wine, and again after the evening meal.
To treat deficiency exhaustion resulting in depletion, cold knees, weakness, frequent urination, and loss of appetite, it is appropriate to administer Shanzhuyu Wan (Cornus Pill).
Shanzhuyu (Fructus Corni, 1 liang) Shuyu (Rhizoma Dioscoreae, 1 liang) Niuxi (Radix Achyranthis Bidentatae, 1.5 liang; remove seed heads) Tianxiong (Radix Aconiti Lateralis Preparata, 1 liang; processed until cracked, remove skin and navel) Tusizi (Semen Cuscutae, 2 liang; soak in wine for three days, sun-dry, and separately pound into powder) Fupenzi (Fructus Rubi, 1 liang) Moli Fen (Concha Ostreae Powder, 1 liang)
The above herbs are pounded, sifted into powder, mixed with refined honey, and pounded 500–700 times until uniform. Form pills the size of paulownia seeds. Take 30 pills each time before meals with warm wine.
To treat deficiency exhaustion with cold knees and to tonify Qi and strengthen vitality, it is appropriate to administer Lurong Wan (Deer Antler Pill).
Lurong (Cornu Cervi Pantotrichum, 3 liang; remove hair, coat with butter, stir-fry until slightly yellow) Guixin (Cortex Cinnamomi, 1 liang) Shihu (Herba Dendrobii, 1 liang; remove roots and slice) Chuangzi (Semen Cnidii, 1 liang) Buguzhi (Fructus Psoraleae, 1 liang; remove heart) Huangqi (Radix Astragali, 1 liang; slice) Shudihuang (Radix Rehmanniae Preparata, 1 liang)
The above herbs are pounded, sifted into powder, mixed with refined honey, and pounded 500–700 times until uniform. Form pills the size of paulownia seeds. Take 30 pills each time before meals with warm wine.
To treat deficiency exhaustion with cold knees, it is appropriate to administer Buyi Huangqi Infused Wine (Tonifying Astragalus Infusion).
Huangqi (Radix Astragali, 1 liang; slice) Bixie (Rhizoma Dioscoreae Hypoglaucae, 1.5 liang; slice) Fangfeng (Radix Saposhnikoviae, 1.5 liang; remove radicle) Niuxi (Radix Achyranthis Bidentatae, 2 liang; remove seed heads) Guixin (Cortex Cinnamomi, 1 liang) Shinanye (Folium Nandinae, 1 liang) Fuzi (Radix Aconiti Lateralis Preparata, 1 piece; processed, remove skin and navel)
The above herbs are finely sliced, placed in a silk bag, and soaked in 2 dou of wine in a porcelain jar. Seal the jar tightly. After three days, warm one small cup and drink it before meals.
To treat deficiency exhaustion damage, Kidney and lower back pain, cold knees with weakness, and to tonify and preserve youthfulness, it is appropriate to administer Tusizi Wan (Cuscuta Pill).
Tusizi (Semen Cuscutae, 3 liang; soak in wine for three days, sun-dry, and separately pound into powder) Cheqianzi (Semen Plantaginis, 2 liang) Baizhu (Rhizoma Atractylodis Macrocephalae, 2 liang) Guixin (Cortex Cinnamomi, 2 liang) Duzhong (Cortex Eucommiae, 2 liang; scrape off rough bark, stir-fry until slightly yellow, and slice)
The above herbs are pounded, sifted into powder, mixed with refined honey, and pounded 500–700 times until uniform. Form pills the size of paulownia seeds. Take 30 pills each time before meals with warm wine.
To treat deficiency exhaustion with cold knees, there is also the Fuzi Wan (Aconite Pill).
Fuzi (Radix Aconiti Lateralis Preparata, 8 liang; each morning soak in fresh well water, changing the water once daily for seven days, remove black skin, slice thinly, sun-dry, and pound into powder) Shihu (Herba Dendrobii, 4 liang; remove roots and slice)
The above herbs are pounded, sifted into powder, mixed with refined honey, and pounded over 1,000 times until uniform. Form pills the size of paulownia seeds. Take 30 pills each time before meals with warm wine.
To treat deficiency exhaustion with severe weakness, failure of Yang leading to impotence, and cold knees, it is appropriate to administer Zhongru Wan (Stalactite Pill).
Zhongru Fen (Arctostaphylis Powder / Stalactite Powder, 3 liang) Chuangzi (Semen Cnidii, 3 fen) Shihu (Herba Dendrobii, 1 liang; remove roots and slice) Tusizi (Semen Cuscutae, 3 liang; soak in wine for three days, sun-dry, and separately pound into powder)
The above herbs are pounded, sifted into powder, mixed with refined honey, and pounded 300–500 times until uniform. Form pills the size of paulownia seeds. Take 30 pills each time before meals with warm wine.