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Wang Shishan stated: Women belong to Yin and take blood as their root. However, humans emulate Heaven and Earth, where Yin is often insufficient; women additionally suffer consumption from nursing and menstruation, thus many women suffer from blood diseases. Menstrual blood (Jingyue) is formed from body fluids (Jinye) and blood vessels. If Ying and Wei (Nutritive and Defensive Qi) are harmonious, menstruation will naturally occur on schedule, like the waxing and waning of the moon, without deviating from its regular measure, hence it is called "Menstrual Blood." If Qi and Blood encounter even slight disorder, menstruation may come early or late, with unequal volume, or become amenorrheic (Bi Jue), giving rise to various diseases; one must differentiate the cause and treat accordingly. In cases of depletion of True Water (Zhen Shui, referring to Kidney Yin) with internal blazing of Yang Fire, leading to exhaustion of the Sea of Blood (Xue Hai) and cessation of menstruation, one should tonify and nourish Yin Blood, so that menstruation will flow naturally. In cases where Cold pathogens lodge in the uterine gate (Bao Men), causing coagulation and stasis in the uterus (Zi Hu), resulting in blood obstruction and signs of mass formations (Jia), one should disperse Cold and expel Stasis, so that menstruation will flow naturally. However, Blood is the companion of Qi; its ascending/descending, cold/heat, deficiency/excess all follow Qi. Thus, if Qi is hot, Blood becomes hot and dark purple; if Qi is cold, Blood becomes cold and congealed; if Qi ascends, Blood rebels and flows upward (hemorrhage); if Qi sinks, Blood follows and collapses downward (metrorrhagia). Therefore, regulating menstruation prioritizes nourishing Blood, and nourishing Blood prioritizes regulating Qi.

Fang Yuezhi stated: Women function primarily through Blood; when Qi moves freely, there is no disease. Hence, ancient physicians treating women's diseases frequently used Cyperi Rhizoma (Xiangfu), Amomi Fructus Rotundus (Sharen), Aucklandiae Radix (Muxiang), Citri Reticulatae Pericarpium (Qingpi), and Aurantii Fructus Immaturus (Zhike) because these herbs promote Qi movement. Most women's diseases stem from Qi and Blood stagnation; therefore, treatment focuses on resolving stagnation and promoting Qi circulation. Once stagnation is resolved and Qi circulates, menstruation will regulate itself, and various ailments will heal.

Ye Yiqian stated: For irregular menstruation in women, there is often a theory advocating the depletion of Qi and augmentation of Blood. However, Blood is the companion of Qi; if Qi is hot, Blood is hot; if Qi is cold, Blood is cold; if Qi ascends, Blood ascends; if Qi descends, Blood descends; if Qi moves, Blood moves; if Qi stagnates, Blood stagnates. Only in cases where stagnant Fire dominates the Blood level, causing irregular menstruation, can one solely use Xiangfu Wan (Cyperi Pill) or Yi Qi San (Suppress Qi Powder) augmented with Aucklandiae Radix (Muxiang) and Arecae Semen (Binglang) to resolve stagnation and move Qi. If Qi is chaotic, regulate it; if Qi is cold, warm it; if Qi is deficient, tonify it—this applies equally to men and women. When Yang grows, Yin increases; when Qi declines, Blood also weakens. How can one merely deplete Qi? Nevertheless, in some cases, disharmony between husband and wife, or the frustration of maidservants or relatives, leads to persistent Qi stagnation causing irregular menstruation; in such instances, one must examine the patterns of compliance and rebellion to treat them appropriately.